I just want to give words of encouragement to other stage IV metastatic prostate cancer patients. I have been following the regimen discussed in this video, under the care of Dr. Eugene Kwon, for a year now (Lupron, Nubeqa, Taxotere, Radiation.) and it has worked to perfection.
Hi Fred, thank you for that , good to know, I am interested what country are you in to get this what I would call straight forward sensible treatment ?, I am in UK, north , my oncologists etc are also in UK the problem is I am in 2024 they are in some where around 1976 regarding treatment options
I will second this comment. I wasDiagnosed in Nov 22, did radiation on bone Mets followed by triple therapy (taxotere, firmagon, nubeqa) and have had an undetectable PSA last nine months. Looking forward to getting off ADT if I can.
Grand Rounds in Urology, Cancer Patient Lab are also excellent. These three I watch regularly, although it can be depressing as a good number of these treatments are not available in Canada yet.
I live in the UK and I have a PSA of 80 & I'm 62yrs old. It was all a surprise as I am asymptomatic apart from getting up a few times in the night. I asked my doctor for a PSA test 7 months ago but I was talked out of it as he said PSA test are not reliable and cited false positive and painful biopsies etc. I've had my 1st ever PSA test in the last few weeks and following bone scans and an MRI scan, I've been diagnosed with metastatic prostate cancer which has spread some of my bones. I am due a biopsy this week to see what type of cancer it is and these 3 treatments have been mentioned as part of ongoing treatment etc. As you can imagine, I'm very angry as 7 months is a long time for the cancer to have spread. I know that I can't be sure of this but I would urge anyone in the UK to insist in having a PSA test as a matter of urgency. Our NHS (public medical) is great in an emergency but is severely lacking during primary care. You videos have help me immensely and give me hope that there is a future. I hope my consultant is just as revered and competent as #MarkScholzMD
Best wishes to you in your journey! As you’ve probably seen from watching these videos, there IS light at the end of the tunnel. My advice is to watch all the videos,, take good notes, and collate them however works best for you, so you are armed with at least as much knowledge (if not more) than your doctors. The treatments nowadays are amazing. Follow the regimen, stay determined and ever grateful for all the good you’ve experienced in life, and you can get through this!
Diagnosed in Feb 20, 2024 63 yrs old. PSA 255. Urologist treated me for urinary infection said come see me in six weeks. My family Doc set me up an MRI, showed large tumor in prostate and widespread throughout my pelvis. Had PSMA-PET scan. Went on Eligard , Nubeqa, had radiation therapy to bone and prostate, and now going in for my 5th Docetaxel treatment on the 13th. PSA was 1.2 last treatment. I have never had a prostate biopsy only bone biopsy. Thank you PCRI
Thank God for your family doc, and best wishes in your battle. I was diagnosed in February as well, via a prostate biopsy. PSMA Pet scan revealed cancer in half of prostate, one seminal vesicle, and one local lymph node. Firmagon and Aberiterone lowered PSA from 87 to 3 in less than four weeks. Since then I’ve completed 28 radiation sessions. Will get my PSA checked again in October. The docs all agreed that checking any sooner might be confusing due to irritation caused to the prostate by radiation. I’m still on hormone therapy, of course, feeling good and hoping to continue making progress in my own battle. Take care! Update: PSA is undetectable as of October , 2024. Doing weight training 3 to 4 times a week to address the worst of the hormone treatments side effects. Feeling good in December and hoping to continue making progress!
@@bluloj7121 emotions, brain fog, sweats, all manageable. The hormone therapy is the worst of the treatments. PSA 0.1 in seven months, I'm in remission.
I appreciate all the information this channel is providing to everyone as a 77yrs young person having to undergo radical prostatectomy at age 68 and was told I was fully cure with psa 0.080 for 7 yrs, with a recurrence in 2022 with psa10 having done PSMA Pet scan shows a small nodule that was extracted and psa fell to 0.080 started on lupron22.5mg (Eligard) every 3months after which i did a full pect ct scan that shows metastasis on my L5 and hip bone since then still on lupron injection 22.5 mg bicalutamide 50mg daily and abiraterone 250mg, recently did a blood test that shows psa at 42.3 and Dr increased dosage of aberaterone to 1000mg and 10mg presdnisone and requested another pect ct scan.Its been rough but the good Lord takrs care of us and must be patient.thanks for your so important info.❤
My question is about the survival rate of metastatic prostate cancer over 5 years. Many sites on the internet say men have a 30% chance of surviving 5 years. I get the impression that this is quite a bit higher these days as 30% is quite low. How can l get accurate information regarding survival rates? My husband has metastatic pc with 2 bone mets and 2 lymph nodes affected. He's 69 . He is on 1st and 2nd generation hormone therapy but not chemo yet. His doctor said he has years not months but this is pretty vague . Thankyou.
A family member was scheduled for 6 cycles of Taxotere, but decided not to do the 6th cycle due to onset of Neuropathy which caused balance issues after the 5th cycle. The PSA went down to .18 after the 5th cycle. A repeat PET PSMA is scheduled.
🎯 Key points for quick navigation: 00:00 *📈 Introduction to Triple Therapy for Advanced Prostate Cancer* - Discusses diagnosis and high PSA with metastatic activity, - Introduction of Dr. Mark Scholz, focused on prostate cancer, - Key questions: what is triple therapy, side effect concerns, and treatment availability. 00:45 *💼 Eligibility for Triple Therapy* - Typical case for triple therapy: high PSA, metastatic disease, - Benefits of first and second-generation hormone treatments plus chemotherapy, - Higher Gleason scores more likely for this situation. 03:38 *🎯 Deciding on Triple Therapy* - Criteria for triple therapy: bone versus lymph node metastasis, - Debate over chemotherapy necessity with lymph node-only disease, - Quality of life and cure considerations influence treatment decisions. 07:28 *🌟 Triple Therapy in Young Patients* - Importance of cure over control in younger patients, - Lack of solid data on cure rate improvement with triple therapy, - Potential for higher cure rates with additional treatments. 09:06 *🩺 Side Effects of Treatment* - Hormone therapy side effects are well known and manageable, - Taxotere side effects, excitement about preventing hair loss, - Consideration of side effects in treatment decision-making. 11:38 *⏳ Timing and Duration of Treatments* - Hormone therapy usually starts immediately post-diagnosis, - Flexible timing of radiation and chemotherapy, - Typical hormone therapy duration for metastatic disease. 13:31 *🔍 Role of PSMA in Therapy Decisions* - PSMA scan's utility before ceasing hormone treatment, - Patients' misconceptions on PSA levels and hormone therapy continuation, - Insignificant utility of PSMA scans when PSA is very low. 15:20 *💊 Chemotherapy Specifics in Prostate Cancer* - Taxotere as a standalone treatment rather than in combination, - Lower doses than in other cancers, reducing side effects, - Differentiating prostate cancer chemo from other types. 18:03 *🔄 Treatment Recurrence and Future Planning* - Possibility of repeating treatments like hormone therapy, radiation, - Consideration of future treatment innovations versus current aggressive treatment, - Strategy adjustments based on disease progression or recurrence. 19:29 *🏥 Importance of Treatment Location* - Variation in care quality between community and specialized centers, - Radiation precision as a key risk factor for long-term outcomes, - Recommendation to seek experienced centers for radiation therapy. 20:55 *🏥 Importance of a supportive medical team and communication* - Critical to have a communicative medical team to address treatment side effects, - Having a support system including caregivers and/or support groups is beneficial, - Managing the psychological and financial stresses of prostate cancer. 22:06 *💪 Quality of life and weightlifting benefits* - Quality of life should be prioritized alongside disease control, - Weightlifting can alleviate treatment-related fatigue by up to 80%, - Future plans for a weightlifting program to aid in muscle mass building. 23:01 *📞 Available support and information resources* - Importance of acknowledging personal needs and communicating them, - The availability of a helpline for guidance on prostate cancer-related inquiries, - Encouragement to utilize resources for better patient outcomes. Made with HARPA AI
Wow, that is me. All three, I came in with PSA 51 and G9, biopsy confirmed 1-12-2024. Bone scan found met.in 5 area. After watching you videos, begged Oncologist to request a PMSA scan, they said they don't usually order those because never approved. Ins.spproved it, since I have stage 4 met.cancer with 2 years to live. This is what they said to me. We did the PSMA scan and found more tumors on lung, liver,spin,throt and stomach. My question is, if all three don't work, what is the best secondary treatment I should be looking at. Thank you again. John
I don't know which is best for you, you should consult this with your medical oncologist. Here are some choices: Pluvicto (Lutetium-177). Stronger chemo: add carboplatin to docetaxel/cabazitaxel. Olaparib (Lynparza) if you have BRCA1/2 genome. The least toxic of these may be Pluvicto.
My husband 65, had a PSA of 4.7--but because it went up 2 points in 6 months, Gleason 4+3=7, MRI, PSMA, 4k, he has prostate cancer. He is in treatment right now.
A family member was checked, found to have high PSA and difficulty peeing. Urologist was repeatedly convinced it was just Prostatitis and prescribed antibiotics and did ultrasound which showed nothing. This went on for months. Family member said I am not getting better and then finally an MRI was done which showed suspicions for cancer. Then biopsy and diagnosis of stage 4 Metastatic Prostate CA with mets in bones and a lymph node. The family member happened to tell this MD on his first consultation that his father had prostate cancer and that should have been a red flag for the MD. Almost a year lost in treatment.
My husband has stage 4 metastatic prostate cancer with spread to 2 lymph nodes and 2 bone mets. My question is just 1st and 2nd generation hormone therapy enough for his situation? You say people with 5 or more metastasis sites should have taxotere. So as he has 4 mets is hormones therapy enough or should we push for taxotere as well? Also we asked the oncologist about a having a break from hormone therapy when psa is negligible and she said ithe cancer is in the bloodstream and he can never stop taking it. We are in Australia if this makes a difference. Thankyou Alex snd Dr Scholz for all your wonderful information to prostate cancer sifferers all over the world.And thank you for answering my last uestion about survival rates for metastatic prostate cancer. Your answer was very reassuring. God bless you both ❤😊
A 78 year old man went for regular PSA tests and physical exams, latest check August 2023. No indication of a problem. January 2024 he had blood in urine. In March 2024, PSA scan showed multiple lesions on axial skeleton, spine, pelvis, scapula etc. Stage 9 Gleason. PSA at 10. Was placed on Eligard / Lupron in February. By late May PSA had dropped to 0.36. Oncologist recommended not proceeding with chemotherapy due to rapidly dropping PSA score. Rather keep chemotherapy in reserve. Should the patient proceed with chemotherapy?
Hi. Some links to the research on triple therapy would be useful. My PSA started at 3,500, heavily metastasized, over six months on ADT dropped to 0.6 Spoke to my medical oncologist about triple therapy but he wants to keep tools in reserve. I could do with maybe showing him some papers.
In 10/2023 my PSA was 310, Gleason 5+4 and metastasised throughout skeleton ( Bone and CT scans - PSMA PET not available ) Was started on 1st generation ADT, immediately followed by Chemotherapy x 6 and 2nd generation Nubeqa. PSA dropped to .10 ( or below ) in 03/2024. Now on ADT and Nubeqa until PSA increases.
What do you suggest who was (61 yrs) diagnosed with Gleason 9, with negative PSMA PET Scan treated with radical radiation therapy and ADT for 3 years. His PSA is beginning to rise again and the repeat PSMA is still normal. Can he go back on ADT with our workout chemo?
Hello, we are not able to answer case questions on our comment section but we can help you through our Helpline who can speak with you either by phone or email. Here is the link to contact them: pcri.org/helpline
Hello, we are not able to answer case questions on our comment section but we can help you through our Helpline who can speak with you either by phone or email. Here is the link to contact them: pcri.org/helpline
Husband, age 60 had only12 lymph nodes in pelvis/abdominal region at dx. He had a severe reaction after 1 infusion of docetaxel and was discontinued. He's only on Xtandi, since refused ADT, and PSA is slowly rising now and urologist is wanting to add Pluvicto. I am worried about neutropenia because of chemo reaction. What other options do you suggest? He doesn't qualify for BAT because of high Testosterone. Also he has not had any radiation yet. Looking into prostatic chemoembolization as an option.
Was that an allergic reaction to docetaxel? Has he had Benadryl prior the infusion? If he tried docetaxel again then maybe try slower speed of delivery, Benadryl and steroids (dexamethasone), maybe . Or try to switch to cabazitaxel instead of docetaxel. Against neutropenia: Routine in top hospitals is to use Neulasta (with claritin) with docetaxel or cabazitaxel. He should consider ADT. Fatigue can be dealt with working out, possible temporary erectile dysfunction can be treated with pills.
@SeekingWisdom17 I didn't know about Neulasta then as I do now. We tried to ask about doing lower dose docetaxel but MO refused saying there is no efficacy which I have found supporting evidence that there is. However, he won't do it anyway. I don't believe he has an allergy to docetaxel. It was cytotoxic reaction resulting in fluid restoration. He went syncope several times after that chemo for a few days. I have been trying to convince him to start orgovyx. One of the guys from PCRI called and explained it to him. So I think he is on board now. He wants to do another psa and if it's elevated again he will start.
I wonder why LDR (low dose radiation) brachytherapy is not discussed more? Dr. Ankit Agarwal and Dr. Steven Kurtzman, are Radiation Oncologists in Mountain View, CA, they are the two best MD's for this procedure in the nation.
@@shelleyhale563 While that may be true, I clipped this from a Joe Rogan video before it was removed. >>Was diagnosed with Prostate cancer Gleason 7 (3+4) at the age of 37. I knocked back all urologists recommendations and used Fenbendazole 1500mg-2000mg a day. My recent 2 year biopsy stated I have eradicated 3 out of my 4 tumors. I personally believe this stuff works
@@shelleyhale563 I have dozens of these, of course, they will be removed, however, Dr. Tom Roger's video on artemisinin and fenbendazole is still up and the comments are pretty wild as well. >>Fenbendazole! My brother-in-law has been symptom free for three years now, from Stage 4 metastatic prostate cancer , using this drug daily
Yes but they don't always give it here in Texas. Stage 4, I want to try it all to save my self. The Dr. Won't speak to me about alternative or diet. As if they just want money and not cure. Only my thoughs, I want this 6 month nightmare to end...
All the information shows me that I do not want to live through this.I am on adt 4 months and I see only worsening side effects and deteriorating mental health. My wife died of breast cancer 22 years ago. The medical industry failed her and deceived me with optimism that was unfounded.
I just want to give words of encouragement to other stage IV metastatic prostate cancer patients. I have been following the regimen discussed in this video, under the care of Dr. Eugene Kwon, for a year now (Lupron, Nubeqa, Taxotere, Radiation.) and it has worked to perfection.
Hi Fred, thank you for that , good to know, I am interested what country are you in to get this what I would call straight forward sensible treatment ?, I am in UK, north , my oncologists etc are also in UK the problem is I am in 2024 they are in some where around 1976 regarding treatment options
@@n.c.b.8832I understand that Dr. Kwon operates in the USA.
I will second this comment. I wasDiagnosed in Nov 22, did radiation on bone Mets followed by triple therapy (taxotere, firmagon, nubeqa) and have had an undetectable PSA last nine months. Looking forward to getting off ADT if I can.
@@n.c.b.8832Hi. I’m also in the UK. Similar diagnosis to Fred. Have had the same treatment but without Radiation. PSA was 310 - now down to below .01.
This channel is the best by far for prostate cancer information. I have learned so much by watching your videos.
Thank you.
Grand Rounds in Urology, Cancer Patient Lab are also excellent. These three I watch regularly, although it can be depressing as a good number of these treatments are not available in Canada yet.
@@frankperham5629 I totally agree - it's a great channel.
From Dublin, Ireland. 🇨🇮
I live in the UK and I have a PSA of 80 & I'm 62yrs old. It was all a surprise as I am asymptomatic apart from getting up a few times in the night. I asked my doctor for a PSA test 7 months ago but I was talked out of it as he said PSA test are not reliable and cited false positive and painful biopsies etc. I've had my 1st ever PSA test in the last few weeks and following bone scans and an MRI scan, I've been diagnosed with metastatic prostate cancer which has spread some of my bones. I am due a biopsy this week to see what type of cancer it is and these 3 treatments have been mentioned as part of ongoing treatment etc. As you can imagine, I'm very angry as 7 months is a long time for the cancer to have spread. I know that I can't be sure of this but I would urge anyone in the UK to insist in having a PSA test as a matter of urgency. Our NHS (public medical) is great in an emergency but is severely lacking during primary care. You videos have help me immensely and give me hope that there is a future. I hope my consultant is just as revered and competent as #MarkScholzMD
Best wishes to you in your journey! As you’ve probably seen from watching these videos, there IS light at the end of the tunnel. My advice is to watch all the videos,, take good notes, and collate them however works best for you, so you are armed with at least as much knowledge (if not more) than your doctors. The treatments nowadays are amazing. Follow the regimen, stay determined and ever grateful for all the good you’ve experienced in life, and you can get through this!
Diagnosed in Feb 20, 2024 63 yrs old. PSA 255. Urologist treated me for urinary infection said come see me in six weeks. My family Doc set me up an MRI, showed large tumor in prostate and widespread throughout my pelvis. Had PSMA-PET scan. Went on Eligard , Nubeqa, had radiation therapy to bone and prostate, and now going in for my 5th Docetaxel treatment on the 13th. PSA was 1.2 last treatment. I have never had a prostate biopsy only bone biopsy. Thank you PCRI
Thank God for your family doc, and best wishes in your battle. I was diagnosed in February as well, via a prostate biopsy. PSMA Pet scan revealed cancer in half of prostate, one seminal vesicle, and one local lymph node. Firmagon and Aberiterone lowered PSA from 87 to 3 in less than four weeks. Since then I’ve completed 28 radiation sessions. Will get my PSA checked again in October. The docs all agreed that checking any sooner might be confusing due to irritation caused to the prostate by radiation. I’m still on hormone therapy, of course, feeling good and hoping to continue making progress in my own battle. Take care!
Update: PSA is undetectable as of October , 2024. Doing weight training 3 to 4 times a week to address the worst of the hormone treatments side effects. Feeling good in December and hoping to continue making progress!
@@edg531 The best to you as well, thank you.
@@ovidididaho Hoping for a speedy recovery.
How bad or not so bad were your side effects?
@@bluloj7121 emotions, brain fog, sweats, all manageable. The hormone therapy is the worst of the treatments. PSA 0.1 in seven months, I'm in remission.
@@edg531 wow! you are doing good. keep it up.
I appreciate all the information this channel is providing to everyone as a 77yrs young person having to undergo radical prostatectomy at age 68 and was told I was fully cure with psa 0.080 for 7 yrs, with a recurrence in 2022 with psa10 having done PSMA Pet scan shows a small nodule that was extracted and psa fell to 0.080 started on lupron22.5mg (Eligard) every
3months after which i did a full pect ct scan that shows metastasis on my L5 and hip bone since then still on lupron injection 22.5 mg bicalutamide 50mg daily and abiraterone 250mg, recently did a blood test that shows psa at 42.3 and Dr increased dosage of aberaterone to 1000mg and 10mg presdnisone and requested another pect ct scan.Its been rough but the good Lord takrs care of us and must be patient.thanks for your so important info.❤
Hope you have recovered. God bless.
My question is about the survival rate of metastatic prostate cancer over 5 years. Many sites on the internet say men have a 30% chance of surviving 5 years. I get the impression that this is quite a bit higher these days as 30% is quite low. How can l get accurate information regarding survival rates? My husband has metastatic pc with 2 bone mets and 2 lymph nodes affected. He's 69 . He is on 1st and 2nd generation hormone therapy but not chemo yet.
His doctor said he has years not months but this is pretty vague .
Thankyou.
A family member was scheduled for 6 cycles of Taxotere, but decided not to do the 6th cycle due to onset of Neuropathy which caused balance issues after the 5th cycle. The PSA went down to .18 after the 5th cycle. A repeat PET PSMA is scheduled.
Below de wormer?I've been treated for 5 yrs and say there's nothing else than they can do for me,thanks for all your info for the last 5 yrs❤
Very enlightening to us patients. Thank You so much! Highly appreciated!
I’m advanced p ca . I’m so grateful for your work.
Very helpful and comprehensive video on triple therapy, thanks!
🎯 Key points for quick navigation:
00:00 *📈 Introduction to Triple Therapy for Advanced Prostate Cancer*
- Discusses diagnosis and high PSA with metastatic activity,
- Introduction of Dr. Mark Scholz, focused on prostate cancer,
- Key questions: what is triple therapy, side effect concerns, and treatment availability.
00:45 *💼 Eligibility for Triple Therapy*
- Typical case for triple therapy: high PSA, metastatic disease,
- Benefits of first and second-generation hormone treatments plus chemotherapy,
- Higher Gleason scores more likely for this situation.
03:38 *🎯 Deciding on Triple Therapy*
- Criteria for triple therapy: bone versus lymph node metastasis,
- Debate over chemotherapy necessity with lymph node-only disease,
- Quality of life and cure considerations influence treatment decisions.
07:28 *🌟 Triple Therapy in Young Patients*
- Importance of cure over control in younger patients,
- Lack of solid data on cure rate improvement with triple therapy,
- Potential for higher cure rates with additional treatments.
09:06 *🩺 Side Effects of Treatment*
- Hormone therapy side effects are well known and manageable,
- Taxotere side effects, excitement about preventing hair loss,
- Consideration of side effects in treatment decision-making.
11:38 *⏳ Timing and Duration of Treatments*
- Hormone therapy usually starts immediately post-diagnosis,
- Flexible timing of radiation and chemotherapy,
- Typical hormone therapy duration for metastatic disease.
13:31 *🔍 Role of PSMA in Therapy Decisions*
- PSMA scan's utility before ceasing hormone treatment,
- Patients' misconceptions on PSA levels and hormone therapy continuation,
- Insignificant utility of PSMA scans when PSA is very low.
15:20 *💊 Chemotherapy Specifics in Prostate Cancer*
- Taxotere as a standalone treatment rather than in combination,
- Lower doses than in other cancers, reducing side effects,
- Differentiating prostate cancer chemo from other types.
18:03 *🔄 Treatment Recurrence and Future Planning*
- Possibility of repeating treatments like hormone therapy, radiation,
- Consideration of future treatment innovations versus current aggressive treatment,
- Strategy adjustments based on disease progression or recurrence.
19:29 *🏥 Importance of Treatment Location*
- Variation in care quality between community and specialized centers,
- Radiation precision as a key risk factor for long-term outcomes,
- Recommendation to seek experienced centers for radiation therapy.
20:55 *🏥 Importance of a supportive medical team and communication*
- Critical to have a communicative medical team to address treatment side effects,
- Having a support system including caregivers and/or support groups is beneficial,
- Managing the psychological and financial stresses of prostate cancer.
22:06 *💪 Quality of life and weightlifting benefits*
- Quality of life should be prioritized alongside disease control,
- Weightlifting can alleviate treatment-related fatigue by up to 80%,
- Future plans for a weightlifting program to aid in muscle mass building.
23:01 *📞 Available support and information resources*
- Importance of acknowledging personal needs and communicating them,
- The availability of a helpline for guidance on prostate cancer-related inquiries,
- Encouragement to utilize resources for better patient outcomes.
Made with HARPA AI
Wow, that is me. All three, I came in with PSA 51 and G9, biopsy confirmed 1-12-2024. Bone scan found met.in 5 area. After watching you videos, begged Oncologist to request a PMSA scan, they said they don't usually order those because never approved. Ins.spproved it, since I have stage 4 met.cancer with 2 years to live. This is what they said to me. We did the PSMA scan and found more tumors on lung, liver,spin,throt and stomach.
My question is, if all three don't work, what is the best secondary treatment I should be looking at.
Thank you again.
John
Lutetium 177, my guess
Call the number of Prostate cancer research institute. You can get information there.
I don't know which is best for you, you should consult this with your medical oncologist. Here are some choices: Pluvicto (Lutetium-177). Stronger chemo: add carboplatin to docetaxel/cabazitaxel. Olaparib (Lynparza) if you have BRCA1/2 genome. The least toxic of these may be Pluvicto.
Hello John, please reach out to our Helpline at pcri.org/helpline. They can talk to you about further options.
I would like you to address paralysis caused by metastaes prostate cancer.
My father 69 at the time went from a PSA of 3.9 to 5000 in one year (2021/2022) it’s not always a lack of checking.
Wow. I had no idea that was possible.
How about HDT and cardio and stroke side effects? Do not hear anything mentioned about it ...
Hi abi, I too got caught out in 2021, no checks done , why ? Covid !!! It will not say Covid on my death certificate but a massive contribution Phil
My husband 65, had a PSA of 4.7--but because it went up 2 points in 6 months, Gleason 4+3=7, MRI, PSMA, 4k, he has prostate cancer. He is in treatment right now.
A family member was checked, found to have high PSA and difficulty peeing. Urologist was repeatedly convinced it was just Prostatitis and prescribed antibiotics and did ultrasound which showed nothing. This went on for months. Family member said I am not getting better and then finally an MRI was done which showed suspicions for cancer. Then biopsy and diagnosis of stage 4 Metastatic Prostate CA with mets in bones and a lymph node. The family member happened to tell this MD on his first consultation that his father had prostate cancer and that should have been a red flag for the MD. Almost a year lost in treatment.
Exercise video I'm looking forward to, that is not easy to find good information about. Thanks for all your efforts and videos to get us informed!
More information on cognitive & emotional side effects of triple treatment would be helpful.
My husband has stage 4 metastatic prostate cancer with spread to 2 lymph nodes and 2 bone mets. My question is just 1st and 2nd generation hormone therapy enough for his situation? You say people with 5 or more metastasis sites should have taxotere. So as he has 4 mets is hormones therapy enough or should we push for taxotere as well?
Also we asked the oncologist about a having a break from hormone therapy when psa is negligible and she said ithe cancer is in the bloodstream and he can never stop taking it.
We are in Australia if this makes a difference.
Thankyou Alex snd Dr Scholz for all your wonderful information to prostate cancer sifferers all over the world.And thank you for answering my last uestion about survival rates for metastatic prostate cancer. Your answer was very reassuring. God bless you both ❤😊
I'd like to know if the prostate has been removed in these scenarios.
A 78 year old man went for regular PSA tests and physical exams, latest check August 2023. No indication of a problem. January 2024 he had blood in urine. In March 2024, PSA scan showed multiple lesions on axial skeleton, spine, pelvis, scapula etc. Stage 9 Gleason. PSA at 10. Was placed on Eligard / Lupron in February. By late May PSA had dropped to 0.36. Oncologist recommended not proceeding with chemotherapy due to rapidly dropping PSA score. Rather keep chemotherapy in reserve. Should the patient proceed with chemotherapy?
Is he also on second-generation ADT like Xtandi/Zytiga/... ?
@@SeekingWisdom17yes
Hi. Some links to the research on triple therapy would be useful. My PSA started at 3,500, heavily metastasized, over six months on ADT dropped to 0.6 Spoke to my medical oncologist about triple therapy but he wants to keep tools in reserve. I could do with maybe showing him some papers.
In 10/2023 my PSA was 310, Gleason 5+4 and metastasised throughout skeleton ( Bone and CT scans - PSMA PET not available ) Was started on 1st generation ADT, immediately followed by Chemotherapy x 6 and 2nd generation Nubeqa. PSA dropped to .10 ( or below ) in 03/2024. Now on ADT and Nubeqa until PSA increases.
What is your opinion of “predict” to determine your prognosis and possible treatment paths.
What do you suggest who was (61 yrs) diagnosed with Gleason 9, with negative PSMA PET Scan treated with radical radiation therapy and ADT for 3 years. His PSA is beginning to rise again and the repeat PSMA is still normal. Can he go back on ADT with our workout chemo?
Was your tumor on both sides of prostate and what was your psa when you were first diagnosed?
Hello, we are not able to answer case questions on our comment section but we can help you through our Helpline who can speak with you either by phone or email. Here is the link to contact them: pcri.org/helpline
Please if a patient has prostate CA which is responsive to hormonal therapy, and confided to only the prostate, should they have radiotherapy,
Hello, we are not able to answer case questions on our comment section but we can help you through our Helpline who can speak with you either by phone or email. Here is the link to contact them: pcri.org/helpline
Husband, age 60 had only12 lymph nodes in pelvis/abdominal region at dx. He had a severe reaction after 1 infusion of docetaxel and was discontinued. He's only on Xtandi, since refused ADT, and PSA is slowly rising now and urologist is wanting to add Pluvicto. I am worried about neutropenia because of chemo reaction. What other options do you suggest? He doesn't qualify for BAT because of high Testosterone. Also he has not had any radiation yet. Looking into prostatic chemoembolization as an option.
Hello Shelley,
We would love to help. Here is the link to our Helpline. They can give you information for your husbands case: pcri.org/helpline
Do the all three, find Chemo that he can stan, and live your life.
Was that an allergic reaction to docetaxel? Has he had Benadryl prior the infusion? If he tried docetaxel again then maybe try slower speed of delivery, Benadryl and steroids (dexamethasone), maybe . Or try to switch to cabazitaxel instead of docetaxel.
Against neutropenia: Routine in top hospitals is to use Neulasta (with claritin) with docetaxel or cabazitaxel.
He should consider ADT. Fatigue can be dealt with working out, possible temporary erectile dysfunction can be treated with pills.
@SeekingWisdom17 I didn't know about Neulasta then as I do now. We tried to ask about doing lower dose docetaxel but MO refused saying there is no efficacy which I have found supporting evidence that there is. However, he won't do it anyway. I don't believe he has an allergy to docetaxel. It was cytotoxic reaction resulting in fluid restoration. He went syncope several times after that chemo for a few days. I have been trying to convince him to start orgovyx. One of the guys from PCRI called and explained it to him. So I think he is on board now. He wants to do another psa and if it's elevated again he will start.
@@shelleyhale563 If he got intense hot flashes from ADT then transdermal estrogen patches would help him with that.
Have you ever heard of someone trying fendbezodol dog de worker? And it working? As a last resort?
👍
Don't wait, true it has none for me side affect.
Do have any more information?@DCGreenZone
@johnmartinez9295 Do you have anymore information?
I wonder why LDR (low dose radiation) brachytherapy is not discussed more? Dr. Ankit Agarwal and Dr. Steven Kurtzman, are Radiation Oncologists in Mountain View, CA, they are the two best MD's for this procedure in the nation.
Hi! Here is a presentation they did with us in September: ua-cam.com/video/GZTK6IcGI-w/v-deo.html
@@ThePCRI Thank you
Thanks
Looking forward for your exercise video.
Cheers
Thanks for the info.
I tick a lot of box's from your phone list.
Do they send medication or from your nominated chemist?
Mebendazole has been added to Docetaxel by the University of Glasgow. Thoughts?
Wow, how can I try that?? Can I ask the Oncologist? Or is this a trail?
If not, I can order Fembendazol, a cousin to that.
Mebendazole is the only version approved now for human use. Integrative oncologists csn order from a compound pharmacy.
@@shelleyhale563 While that may be true, I clipped this from a Joe Rogan video before it was removed.
>>Was diagnosed with Prostate cancer Gleason 7 (3+4) at the age of 37. I knocked back all urologists recommendations and used Fenbendazole 1500mg-2000mg a day. My recent 2 year biopsy stated I have eradicated 3 out of my 4 tumors. I personally believe this stuff works
@@shelleyhale563 I have dozens of these, of course, they will be removed, however, Dr. Tom Roger's video on artemisinin and fenbendazole is still up and the comments are pretty wild as well.
>>Fenbendazole! My brother-in-law has been symptom free for three years now, from Stage 4 metastatic prostate cancer , using this drug daily
Yes but they don't always give it here in Texas. Stage 4, I want to try it all to save my self. The Dr. Won't speak to me about alternative or diet. As if they just want money and not cure. Only my thoughs, I want this 6 month nightmare to end...
Are you aware of HIFU therapy? Who does that work for. Why does not one seem to use it or bring it up . High Frequency.
All the information shows me that I do not want to live through this.I am on adt 4 months and I see only worsening side effects and deteriorating mental health. My wife died of breast cancer 22 years ago. The medical industry failed her and deceived me with optimism that was unfounded.
Fenbendazole is plainly listed for humans on Amazon, 222mg and 444mg. No disrespect, but that's a fact Shelley.