Developing A New Malaria Vaccine!
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- Опубліковано 24 лип 2024
- We've learned a bit about how hummingbirds see motion in an unexpected way, and scientists are working on a potential new malaria vaccine by genetically manipulating the parasite that causes it!
Hosted by: Hank Green
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Sources:
www.cdc.gov/malaria/about/faq...
www.cdc.gov/malaria/about/bio...
hummingbirds.ucdavis.edu/hummi...
www.malariavaccine.org/files/M...
www.researchgate.net/publicat...
stm.sciencemag.org/content/9/3...
www.sciencemag.org/news/2017/0...
www.eurekalert.org/pub_releas...
www.cell.com/current-biology/f...
Images:
commons.wikimedia.org/wiki/Fi...
www.eurekalert.org/multimedia...
commons.wikimedia.org/wiki/Fi...
commons.wikimedia.org/wiki/Fi...
commons.wikimedia.org/wiki/Fi...
commons.wikimedia.org/wiki/Fi...
commons.wikimedia.org/wiki/Fi...
That moment when you don't realize you're watching a two part video and are trying to figure out what hummingbirds have to do with a new malaria vaccine...
Master Therion lmao
Master Therion
It's pretty simple. Hummingbirds can see a malaria vaccine.
ikr ;D
That moment when you read a comment about someone not paying attention to the video, but leaves a comment anyway.
Dragon Ball Super sometimes you comment about what u thought while watching the video ;D
Imagine spreading vaccines with mosquitoes that would be amazing
Dank Lord Some people can't have certain vaccines, but in general, that's a nice idea
Wild Malaria appears!
Wild Anti-Vaxxer's says "Mosquito bites to apply vaccines!? I'm not gonna give my child THAT!"
It's not very effective.
Scientists used Modified P. falciparum Genome!
It's super effective!
Malaria fainted.
Stupid Moms gained 0 EXP. Points.
Science gained 10000 EXP. Points!
Giving the GAP Malaria to all the mosquitoes would also solve the problem of anti-vaxers! :)
That would suck
Could very well be the future, I really think to defeat malaria we should cure the mosquitoes first to prevent it from spreading any further.
Doctor: "you came to get vaccine against malaria?"
Patient: "ye.."
Doctor:" Pleace step into that room over there and let one mosqitoe byte u."
Patient: "umm.. okey i guess.."
Allan Best Comment
so if 100 of those "mosqitoes" "byte" you, do you get a megabyte?
bah dum tsss
gatomaru More like a million to get "mega" ;)
100 bytes would be a hectabyte, to go for a megabyte, you'd have to get bytten 1000000 tymes
lets be specific here, don't get the dosage wrong, its 1,048,576 bytes for a megabyte
Can you please do one on cerebral aneurysms? I had one rupture at 19 and would love to learn more!
To tell the truth, I think I would rather have a mosquito bite than a shot in the arm.
If you think about it a mosquito is just a flying needle which spits it's previous lunch on you afterwards.
Kinky Fish: That and anticoagulants that cause an allergic reaction that makes you itch.
MuffinTastic And have them make a high pitch noise before inserting it.
This comment train is leading me to think about a Mosquito Doctor Monty Python sketch.
It's all a matter of personal preference. I find the discomfort of a mosquito bite very small relative to the discomfort of an injection, even when factoring in the itching. Lab grown mosquitoes would be free of any other disease. Personally, I wish all my vaccinations could be delivered via mosquito.
These scientists deserve the Nobel prize considering that Malaria is the #1 cause of human deaths in our history. It made the mosquito by far, the most deadly animal man ever encountered.
Lets wait until we know it's effective (as opposed to simply not in itself dangerous) in humans. But if it is, and it works in a high enough percentage of the population to create herd immunity, then they deserve not just the Nobel Prize in medicine, but literally every prize that covers the field of medicine, if only on a technicality.
thank you for creating these episodes and doing all the research. my daughter and I love them
Two amazing discoveries that would have been science fiction when I was a teen. I love science.
"Hummingbirds are basically tiny stunt pilots."
-- Hank Green, Truth-sayer
R.Instro *stunt. How did you manage to fuck this up?
Fixed. ^_^;;;;
Well... they're more like what you'd get if a stunt pilot and plane used a fusion technique
Frank is that you? Come back Frank! We need more True Facts videos!
Hummingbird to other birds:. "Do you even flap, bro?"
"If you have a special someone......." Heh. That was quite funny, Hank.
Will love to see the outakes on this one!
I did a presentation on a very similar thing to the malaria news last year in my immunology class! Very promising stuff!
This combined with the work done with Crispr and Gene Drives could Greatly decrease the spread of malaria.
I got an email to be part of a second round of this testing. I had turned them down cause I didn't want to die, but now I wish they had told me a bit more cause I would have totally be apart of this!
That hummingbirnd experiment sounds like a creepy mad scientist experiment tbh
holy shit.
didn't we always know that hummingbirds are the best birds ever.
and also. I was here under a minute.
Why has no study been done to see if hummingbirds actually hum and what it is they hum? A parabolic dish microphone and high quality recording equipment could get someone a Nobel Prize in Biology!
wow, great news. thanks scientists and those financing this research
If you don't mind my correction, Mr. Green, it's 'gametoCYTES' not 'gametoPHYTES' as you stated. But otherwise a FANTASTIC video as always and I love your presentation of all these facts/theories/allothersciencystuffs! :)
Trying to figure out who in the world would volunteer for the malaria experiment and how much were they paid?!?!
That's so complicated, I have to watch it twice...
hole - 1st drill press channel I don't mean to be an ass but... What did u find complicated?
"if you were giraffe u would have the tastiest pee"..woa..someone tasted every animal's pee!!!!!!!!!!!!!?!!!
yay Hanks back :D
Why does the inside of my winshield get wet? And why doesn't the defroster work in that situation?
The brain on the Symptoms of Malaria diagram is upside-down.
So I found a hair in my fries the other day. It doesn't really bother me. but I was wondering how unsanitary is another person's hair in ones food?
There are pills you can take to prevent malaria. I take them before I travel to tropical countries. How is this vaccine different? Are the pills just for mild forms of malaria?
Sounds like what my Girl did to me...lols inputting electrodes and becoming 24/7 walking movie cyborg
Those cards are so cool
Too bad I won't use them
Wasn't this video uploaded already?
funny, most people hate getting shots from hypodermic needles. Perhaps some people would be a little more open to them knowing a mosquito is a possible alternative.
This vaccine sounds really promising!! Very exciting news!
i want to pet a hummingbird. so smol
Last time I was this early, three days Grace was still relevant
I'd rather be bit by a mosquito cuz it doesn't hurt and I don't want to be stabbed by a needle and feel it
Minecreeps7
....hold up, I think you're on to something
Mosquitos are basically flying needles.
Minecreeps7 +
How strange would it be to get your vaccination via mosquitoes..
woohoo! way to go, science!
Haw haw! You said Phalic!
do a video on ''5 cool things about hummingbirds.''
they volunteered to be infected with malaria? Were they paid? What would have happened if they'd been infected?
why do some people wake up at a specific time? I always wake up at exactly 6:00 and can never go back to sleep.
Holly Crap thank for reminding me valentine' s coming!!! a month to go....
And that, dear children, is the lesson for today
I always knew hummingbirds were related to mosquitos.
I mean just look at them. They gigantic, fluffier versions of the same animal.
HANK GREENNNNNNNNNNNNNNNNN
YEAAAAAAAAHHHHHH
It seems like if you wanted to add emphasis, you'd elongate the "ee" rather than the "n".
I missed Hank 😍
HUMMINBIRD FLIES 50KMH?
FUUUUU
damn you guys are fast...
Wait... did those human subjects agree to that experiment knowing that there was a chance they could contract malaria?
Gillian Hutchinson no doubt. They probably received monetary compensation. Or they just wanted to do a service to mankind.
Potential to save "SOME" lives
woooo, yeah science
All they gotta do is choose a random hydrocarbon from the crude oil and if it reduces malaria symptons 5% better than the control group after 15 years of study then that's your new medicine! Just be sure to waive your right to sue if you develop any one of the 20 pages of known side effects.
... What?
Malia vaccine? Finally! Thanks science.
you know another fact about hummingbirds? their also phil lester's past life animal.
You know, if people are starving to death in Africa as it is with the population being somewhat thinned out by malaria, I expect this could just make a few matters worse.
what is so bad about getting vaccinated through mosquitoes?
pramitbanerjee because we are jaded human beings and would feel... uncomfortable having a professional who's been paid to use nothing less than the new medical and overpriced device compared to carrying a box of mosquitoes
+LPCharlie You can actually produce millions of mosquitoes very quickly. It is gross, though.
Wubba Lubba Dub Dub!
Its funny that they managed to modify the parasite that way but dont know how to get it into a f*cking human XD
why do we have birth marks ?
Woo UBC!!
I don5 see the valentine cards on dftba?
nvm found them im blind
I am well aware that the majority of the world uses kilometers for distance and speed and have no problem with you saying that a hummingbird goes from staying in place to moving at 50 km per hour. For those of us that are I the USA and grew up on miles per hour or miles in general can you at least put a parentheses with how many mph that would be. I understand that you guys are appeasing the majority with the kilometers measurement but you are alienating those of us that are more familiar with miles. Thank you
Anybody else wants to volunteer?
Honestly I would much rather revive a vaxxine from a mosquito then a needle, I mean sure it would be itchy but needles scare me...
Is that not how most vaccines work?
Diego Sanchez Yes, that's how alot work.
Brendan Williams then why did anyone not think of doing this before? Or was it that they couldn't weakend the malaria virus?
Diego Sanchez considering the virus has 5000 genes, finding a suitable attentuated parasite takes time.
Bingo. They couldn't figure out how to infect us with a safe form of the parasyte. They still don't as right now they need to use mosquitoes to do the actual injection :P
Also, I think it's only recently that we've developed a tool (CRISPR) to accurately remove genes from an organism (CRISPR is apparently cheaper & faster than than other alternatives to gene editing).
it's great but i hate needle and i don't want to see them again, but i don't want to get Malaria
it would be great to make a chamber for immunized mosquito to bite us
Dear Universe, I love you to infinity, Be my Valentine... Forever. Tootles... Wade
Like how it says new malaria vaccine when there never was one in the first place...
mala aria
I'm going to be alone on Valentine's Day.
You're not alone...
i think im alone too... wanna team up m8?
I hope to see a world free of Malaria.
Spirochetes.....
who would volunteer to get bit by a malaria infected mosquito?
Some people would gladly give themselves up for the good of mankind, those are the ones who would volunteer.
I mean people go to freaking war in service of the public good. Malaria kills a lot more people than war.
foisttt
A new vaccine.... Great
Is animal testing okay?
PixelPower Think about this, how do we get shampoo that is able to go in our eyes without any effects? We have to spray animals eyes until we find something that works...
well that depends on a lot of factors lol there are actually videos on that.
IlluminAsianYT
It's better than skipping straight to human testing, at least
Why do babies stare at nothing and smile?
I tried to look for an answer online but all i could found are stupid comments about ghosts and angels. I would like to know why babies do this.
why would anyone name a disease after the new first lady? how offensive.
2019: the new vaccine has failed us!
My birthday is February 14
This will certainly save a lot of lives.
Now to find a way so prevent the people who live in these countries to breed an unsustainable population
The planet does not need more human life, tbh I think theres needs to be a limit on the amount of children allowed to be born from any oe individual, say each person, man or woman is allowed one offspring token. It would reduce teenage pregnancies along with slowly controlling population in this world where we as a species are living so much longer
falciparum op, pls nerf
Well at least it doesn't keep endlessly respawning like vivax...
How come we spend so much effort in keeping more people alive when that only makes the future more grim. The more people, the more food they need, the more energy they consume the faster we drive ourselves to Global Climate Change. More people only makes everything worse. And yet we do everything we can to make more people live longer.
felixthecrazy so if you had malaria would you want everyone to give up on you for the "greater good"?
As an individual with an incurable disease that kills 1 in 4, basically yes. I have to fall back to Mr. Spock, "The needs of the many outweigh the needs of the few.” What's the point of curing cancer if the planet is going to kill billions due to global warming? If we don't get some sort of handle on population growth, malaria, cancer, etc, will be drops in the bucket of things that cause death.
If we stop then there's no point in our existence. Some debate the entire point of life is to give birth to new life.
We are also capable of solving these problems by changing our behavior. We can (and are!) slowing down climate change. It is also for the greater good to solve the root of the problem (us), which can be done in two ways, 1) Keep the number of humans (roughly) constant, or 2) Change everyone so that more of us can exist without being a burden on the ecosystem.
We as a species are choosing the the second, because of we care about each other, and the second option doesn't involve a close family member dying for 'the greater good'. "Not having the problem in the first place" is a good solution to most problems, but having these problems and then being forced to solve them leads to pretty awesome things!
We make more effort for other people to live in this world because we want to show them the awesome stuff that we have experienced during our time here, and watch them grow up to show it to the next generation.
Yes we our sloppy and have made some mistakes as a species, but that isn't a reason to stop!
felixthecrazy Hans Rosling has a pretty good talk on this and the problem wouldn't be quite as big if more people were vegans and zero wasters.
But then there really is no point in living if we had to live a vegan lifestyle.
us humans Terra formed a planet, conquered the animal kingdom, traveled into space and back, and has vaccinations for healing
but we don't know why we dream
Psychology and the human brain is very hard to study, unfortunately.
YOU COVERED ONE TOPIC THAT HASN'T BEEN FLOGGED TO DEATH ON FACEBOOK YET ARE YOU FEELING OK IS THIS A CRY FOR HELP
Just in time to save Franco Loja
Vaccines are precautions not cures!
Ow
Right in the joke
Forehead spectrum measurement relief supporter cell determine
I still prefer gin & tonic.
Love story❤️
Man: Such a lovely day
Girl: Yup
Man: Will you ever break up with me?
Girl: Of course not
Man: Do you love me?
Girl: Yes definitely!
Man: Have you ever cheated on me?
Girl: Hell no!
Man: Wanna hold hands?
Girl: Yes
Man: I have to tell you something...
PLOT TWIST!! READ IT FROM BOTTOM TO TOP!!
A vaccine in a mosquito sounds really useful actually... Can't you potentially spread a mass vaccine like that, just like the real virus spreads?
Why can't they just keep using mosquitoes? I'd rather be vaccinated by them than the traditional poke and squirt.
Yo
Stop opening poor Hummingbird's brains... Not cool.
This seems much less problematic than what we do to chickens.
Woooo I'm early
halloooooo
🌍🌋🌎🌋🌏🗻🌐
learn from phillyd whatever your title is talk about that first
Early