At age 17 in AP Bio class, my teacher described the workings of the mitochondrion in great detail. I was enthralled by the descriptions of carbohydrate metabolism, how energy was withdrawn from it, and how a proton gradient powered actual protein "turbines" that spun as they drove the ATP synthetases. The mitochondrion inspired me to pursue medicine as a career. This video is a wonderous piece of work, a combination of artistic talent and scientific accuracy. It's EXACTLY how I imagined it.
Based upon your username, it looks like you've maintained that passion for medicine as a career. :) As a high school biology teacher, that makes me happy!
@0:41 The bluish barrel-shaped molecule is a chaperone: chaperones help proteins folds into their correct 3-D conformation. @1:11 Together, each rotating “tree” and the stationary part right next to it that keeps the top of the “tree” from rotating is one ATP synthase molecule. @1:14 ADP (yellow-green) is binding to ATP synthase and then ATP (glowing) is being released. @1:28 ADP and ATP are being exchanged through the membrane.
I absolutely love the mitochondria! Without my mitochondria, my cells would be unable to do cellular respiration nor would function properly. My cells biochemical functions wouldn't work properly either. Perhaps its best to have my mitochondria.
+Yuri lol Have you ever read about the Cambrian Period ? Ironically, how you typed from a non living thing(star) come ... the living things (animal, human). If it is chemical evolution then I suppose pain and suffering are chemical imbalance too ...
***** Please allow me to be blunt, evolution is a lie as well as 911, weapon of mass destruction, communists are evil, DDT & cigarettes are harmless. Have u ever heard of Congenital insensitivity to pain ? As the name implied, the person doesn't feel pain, also is a very dangerous condition. In this world we're known & living in, one may be able to take pain away ( only temporary if you have $ ). Some might even minimized suffering through pleasure ... but soon or later they will come back stronger, hence requires bigger "doses" or painkiller and pleasures. Mind you, only one person ever live can help a person who has bigger pain, his name is Jesus ( Yeshua )
Unspeakably beautiful... any plans to add annotations identifying the key proteins, molecules, and ions to help us follow along? I know the basic sequence of events and I could recognize the obvious components (ATP synthase is pretty distinctive!) but it would be awesome to have a step-by-step guide to better appreciate this exquisite intracellular dance!
1. Life has a Motion! [Flatness, Roundness], [Diagonal Alignment], i.e. [The Helix]! 2. What remains? [The Spiral], [The Wave], [A Field of Energy & Particles]! Amen.
This is beautiful. Something so small does such a complicated work. I've just learned this in school (8th grade lol) and it's so fascinating. Some of the functions in our body are done on such a small scale it makes me wonder what a world exists below what our eyes can see.
0:35 I was in bio class today and my teacher had this on when we were in passing period, and that part where you go in is so cool with the music, it becomes to happy then with the guitar as it looks at the atp synthase stuff
It's a good thing no labels or descriptions of what was happening were added to this, because people might start figuring it out. Good job preventing that from happening!
@0:16 The worm-looking thing is a mitochondrion (plural = mitochondria) @0:22 The strand is a protein and it has particles attached to it to keep it linear, so that it can fit through a protein channel in the membrane. @0:24 The particles are released from the protein as it feeds into and through the protein channel in the outer mitochondrial membrane. @0:26 The protein passes through the space between the outer and inner mitochondrial membranes and then through the inner membrane.
@CalyxAsgard It's the powerhouse component of the cell, which generates ATP (the fuel currency of the cell) responsible for catalyzing various biochemical reactions. It's also responsible for cell apoptosis, among other things.
I am studying the effects of HIV and the drugs used to treat it on the mitochondria. Since the Dr.'s think I'm too stupid to understand it I will find out for myself and pass it on. This is the stuff that completely defies any explantion that we were created by chance.
I'm choking up, this is so beautiful! It really brings to life what we've learnt in molecular biology. Trying to understanding the complexity of cellular biochemistry is something I'm confronted with on a daily basis, and every time I find myself saying, "This is fucking insane!"
That was rather beautiful really. It makes you think about your body and how we take for granted that our body just does most things on its own without our truly being conscious about it.
Too much of this Universe I can't comprehend. The sheer size of the Universe, I can't. This 1 cell doing all this work, than knowing we have something like 7 billion or 7 trillion cells in our body all doing this busy work 24/7 for what?... Too much..
I'm taking biology in college and was about to cry because nothing I was reading made sense! After seeing this and other videos showing what's happening in 3D, I think I'm starting to finally get somewhere 😭
@MikeGinnyMD That's really cool. I'm in college right now studying Chemistry and Biomedical Science. I was hoping to get into medical school, but I don't know if I'll get past the dreaded MCAT! Worst case scenario, I have interests everywhere so finding a graduate program I like shouldn't be a problem. Right now I am taking Organic Chemistry, physics and cellular and molecular biology and I couldn't love my classes more.
This was great, thanks, I have been researching "how to increase mitochondrial count" for a while now, and I think this has helped. Have you ever come across - Miyason Mitochondria Masker - (search on google ) ? Ive heard some pretty good things about it and my buddy got great results with it.
"Scientists who utterly reject evolution may be one of our fastestgrowing controversial minorities. Many of the scientists supporting this position hold impressive credentials in science." ~Larry Hatfield in Science Digest "I believe science is pointing strongly toward design. To me, as a scientist, the development of an embryo cries out, `Design!' The Cambrian explosion-the sudden appearance of complex life, with no evidence of ancestors-is more consistent with design than evolution. Homology, in my opinion, is more compatible with design. The origin of life certainly cries out for a designer. None of these things make as much sense from a Darwinian perspective as they do from a design perspective." ~John Corrigan "Jonathan" Wells (molecular biologist)
+brotherbandit It could be intelligent design, but it's NOT some bullshit "God sent his son to perform miracles and die on the cross" fantasy story that we made up thousands of years ago.
@AzraelUK1 That's an enzyme called ATP synthase. It's the very final step in converting sugars and fats into energy the body can use. It basically acts like a water wheel, using the energy of ions flowing through it to create an energy-rich substance called ATP.
Seeing bioscience through understanding become engineering. Gives us hope. I just love the molecules as machines graphics. It would be nice to see the energy enriching process with annotation or commentary. Not just glowly graphic.
The glowing particles are ATP and the turning protein cranking them out is ATP synthase. The particles turn from a green color (ADP) to a glowing color (ATP) with the addition of an inorganic phosphate.
there are words in my vocabulary that can describe this in they way i want to, but it would be inappropriate. but i can say this. THAT WAS SPECTACULAR!!!!!!!!
If this is supposed to be a literal representation of what goes on in a a single human cell, it's pretty awesome. Like universes within universes!!! It would be helpful, however, to have some kind of narration so we can know exactly what we are looking at at any particular moment.
I thought only my school puts out videos with absolutely no descriptions or explanation of what we are looking at. Great animations, but it would be useful if there were slower transitions and you had time to take in the processes.
Note the Supported by the Howard Hughes institute at the end...these guys don't depend on government whims...the on and off faucets of conservative government (stem cell research etc.) So, they deserve our highest rating...and deepest bows.
I am seriously only here because I've been hunting down this video that we watched in Science class with the song "Finale" from Halo 3 is was part of the same playlist.
@ScootleRoyale What I'm saying is that it takes a huge leap of faith to make those parallels since in the case of the electronics and machines you speak of, we know who actually created it and we can trace it back to a designer, whereas we have no way of knowing for living organisms. But we can definitely say that the theory of evolution best explains the diversity of species through studies in genetics, biochemistry, physical chemistry, organic chemistry, zoology, paleontology, etc.
At age 17 in AP Bio class, my teacher described the workings of the mitochondrion in great detail. I was enthralled by the descriptions of carbohydrate metabolism, how energy was withdrawn from it, and how a proton gradient powered actual protein "turbines" that spun as they drove the ATP synthetases. The mitochondrion inspired me to pursue medicine as a career. This video is a wonderous piece of work, a combination of artistic talent and scientific accuracy. It's EXACTLY how I imagined it.
Based upon your username, it looks like you've maintained that passion for medicine as a career. :) As a high school biology teacher, that makes me happy!
@@cynthiaaaa5204 i am also giving mbbs entrance exam NEET in India on 7th may i studied alot from 3 years
same my Biology professor teach this very deep with animations and slides in Cell the unit of life chapter
Yo, you are MD now man. Congrat
@@Flowerthe9big congrats to him
WHY DOES THE MUSIC IN THESE VIDEOS ALWAYS HAVE TO BE SO EPIC?!?!
Try dubbing these videos with ST motion picture (entering the cloud) or wrath of Khan (genesis project) soundtracks ;)
haha I was thinking the same thing!!!
Life is epic
Because of the epicness
Epic music discribe a journey, it is a journey, is it not ?
@0:41 The bluish barrel-shaped molecule is a chaperone: chaperones help proteins folds into their correct 3-D conformation.
@1:11 Together, each rotating “tree” and the stationary part right next to it that keeps the top of the “tree” from rotating is one ATP synthase molecule.
@1:14 ADP (yellow-green) is binding to ATP synthase and then ATP (glowing) is being released.
@1:28 ADP and ATP are being exchanged through the membrane.
Thank you!!!
Thank you !
If there were 3d animations like these for every subject in school I would just love to learn about them!
Found this gem during my studies into Mitochondria, ATP, and Glycolysis.
Amazing sub-cellular eye candy.
Mom's magical mitochondria.
Enjoy!
I absolutely love the mitochondria! Without my mitochondria, my cells would be unable to do cellular respiration nor would function properly. My cells biochemical functions wouldn't work properly either. Perhaps its best to have my mitochondria.
This is pretty amazing all around. A little Morgan Freeman could make this Oscar worthy.
absolutely amazing. A mini factory working away 24/7 without us even noticing
I'm in tears. The human body is fascinating!!! Thanks to chemical evolution, coacervates, DNA, RNA etc. *---* We're all dust of the stars...
+Yuri lol Have you ever read about the Cambrian Period ? Ironically, how you typed from a non living thing(star) come ... the living things (animal, human). If it is chemical evolution then I suppose pain and suffering are chemical imbalance too ...
+Khanh Ly
true that!! it is so fascinating and fancyy
true just think about it we have trillions of nucleuses in our body
***** Please allow me to be blunt, evolution is a lie as well as 911, weapon of mass destruction, communists are evil, DDT & cigarettes are harmless.
Have u ever heard of Congenital insensitivity to pain ? As the name implied, the person doesn't feel pain, also is a very dangerous condition. In this world we're known & living in, one may be able to take pain away ( only temporary if you have $ ). Some might even minimized suffering through pleasure ... but soon or later they will come back stronger, hence requires bigger "doses" or painkiller and pleasures. Mind you, only one person ever live can help a person who has bigger pain, his name is Jesus ( Yeshua )
your profile picture is so aesthetic
a wondrous example of the complexities and phenomena of everything that is
I'm doing a report on mitochondria, and I absolutely love this video! I'm gonna share this with all my science geek friends. Thanks!
1:08 my favorite enzyme: ATPase!
Unspeakably beautiful... any plans to add annotations identifying the key proteins, molecules, and ions to help us follow along? I know the basic sequence of events and I could recognize the obvious components (ATP synthase is pretty distinctive!) but it would be awesome to have a step-by-step guide to better appreciate this exquisite intracellular dance!
1. Life has a Motion! [Flatness, Roundness], [Diagonal Alignment], i.e. [The Helix]!
2. What remains? [The Spiral], [The Wave], [A Field of Energy & Particles]! Amen.
This is beautiful. Something so small does such a complicated work. I've just learned this in school (8th grade lol) and it's so fascinating. Some of the functions in our body are done on such a small scale it makes me wonder what a world exists below what our eyes can see.
The mind of the creator is big
0:35 I was in bio class today and my teacher had this on when we were in passing period, and that part where you go in is so cool with the music, it becomes to happy then with the guitar as it looks at the atp synthase stuff
This is so beautiful. I wish I knew more precisely what's happening throughout - a voiceover would be nice.
It's a good thing no labels or descriptions of what was happening were added to this, because people might start figuring it out. Good job preventing that from happening!
@0:16 The worm-looking thing is a mitochondrion (plural = mitochondria)
@0:22 The strand is a protein and it has particles attached to it to keep it linear, so that it can fit through a protein channel in the membrane.
@0:24 The particles are released from the protein as it feeds into and through the protein channel in the outer mitochondrial membrane.
@0:26 The protein passes through the space between the outer and inner mitochondrial membranes and then through the inner membrane.
@CalyxAsgard It's the powerhouse component of the cell, which generates ATP (the fuel currency of the cell) responsible for catalyzing various biochemical reactions. It's also responsible for cell apoptosis, among other things.
I am studying the effects of HIV and the drugs used to treat it on the mitochondria. Since the Dr.'s think I'm too stupid to understand it I will find out for myself and pass it on. This is the stuff that completely defies any explantion that we were created by chance.
This is so awesome when you know what's happening. Sometimes being a Biology major is just plain cool
i love the ending part, it's so beautiful.
All praise to time and chance. The random development of even one of those enzymes would take (10^(10^(10^*(10^(10....))))) years.
WHY DOES THE MUSIC IN THESE VIDEOS ALWAYS HAVE TO BE SO EPIC?!?!
21
This world is amazing~~
woow !!
I'm choking up, this is so beautiful! It really brings to life what we've learnt in molecular biology. Trying to understanding the complexity of cellular biochemistry is something I'm confronted with on a daily basis, and every time I find myself saying, "This is fucking insane!"
The mind of God is big
That was rather beautiful really. It makes you think about your body and how we take for granted that our body just does most things on its own without our truly being conscious about it.
There's a mistake. The c-ring should be rotating clockwise (looking it from the cytosol) while synthesizing ATP.
no, that's a cell from a left-handed person
Gracias a videos como estos es más fácil comprender estos procesos e ir más haya de las explicaciones orales. Muy bueno(:
wow this brings all those bio classes to another level...
You/makers of this are...MAGICAL!
Too much of this Universe I can't comprehend. The sheer size of the Universe, I can't. This 1 cell doing all this work, than knowing we have something like 7 billion or 7 trillion cells in our body all doing this busy work 24/7 for what?... Too much..
Life battles entropy - it's all about keeping it together and focusing energy. The Zen masters were right all along.
I'm taking biology in college and was about to cry because nothing I was reading made sense! After seeing this and other videos showing what's happening in 3D, I think I'm starting to finally get somewhere 😭
i wish they could of showed me this in school instead of reading 20pages about how mitochondria works..... DAMN YOU SCHOOL
@MikeGinnyMD That's really cool. I'm in college right now studying Chemistry and Biomedical Science. I was hoping to get into medical school, but I don't know if I'll get past the dreaded MCAT! Worst case scenario, I have interests everywhere so finding a graduate program I like shouldn't be a problem. Right now I am taking Organic Chemistry, physics and cellular and molecular biology and I couldn't love my classes more.
The Wonders of Creation Reveal Gods Glory!
correct me if im wrong...but is mitochondria the powerhouse cell?
Watching this reminds me that we are magical beings. Beautifully done!
I want a Mario game set in this world.
Sabbat-X you fight Virus Bowser at the end.
Super Mario Cell?
This was great, thanks, I have been researching "how to increase mitochondrial count" for a while now, and I think this has helped. Have you ever come across - Miyason Mitochondria Masker - (search on google ) ? Ive heard some pretty good things about it and my buddy got great results with it.
Damn this is beautiful.
Just the phospholipid membrane looks gorgeous!!! Wonderful job!!!
listened to this in school. LOVED IT!!!!
Thanks for explanation
Would be great for someone to do a voice over to explain what it is that we are seeing. Thanks
animation, lighting, and rendering is of supreme quality and i enjoy watching this video.
How fucking weird is this? When you think about it, it's like we're made up of some weird super advanced alien technology.
Austin Texas That's actually very interesting!
You think this is cool? Search for 'Motor Protein'.
+Austin Texas u r dum and
"Scientists who utterly reject evolution may be one of our fastestgrowing controversial minorities. Many of the scientists supporting this position hold impressive credentials in science."
~Larry Hatfield in Science Digest
"I believe science is pointing strongly toward design. To me, as a scientist, the development of an embryo cries out, `Design!' The Cambrian explosion-the sudden appearance of complex life, with no evidence of ancestors-is more consistent with design than evolution. Homology, in my opinion, is more compatible with design. The origin of life certainly cries out for a designer. None of these things make as much sense from a Darwinian perspective as they do from a design perspective."
~John Corrigan "Jonathan" Wells (molecular biologist)
+brotherbandit It could be intelligent design, but it's NOT some bullshit "God sent his son to perform miracles and die on the cross" fantasy story that we made up thousands of years ago.
Good video!! I've really enjoyed it
Visual with Music makes us interested in science
love it. makes anatomy n phisiology so much more entertaining
@AzraelUK1 That's an enzyme called ATP synthase. It's the very final step in converting sugars and fats into energy the body can use. It basically acts like a water wheel, using the energy of ions flowing through it to create an energy-rich substance called ATP.
thus far best movie i've ever seen, great job!!!
Best of luck to your in the rest of your education and career! We need more people like you in the US!
Wunderschön...
Sehr beeindruckend!
Seeing bioscience through understanding become engineering. Gives us hope. I just love the molecules as machines graphics. It would be nice to see the energy enriching process with annotation or commentary. Not just glowly graphic.
The glowing particles are ATP and the turning protein cranking them out is ATP synthase. The particles turn from a green color (ADP) to a glowing color (ATP) with the addition of an inorganic phosphate.
That mitochondrion reminded me of a CCS-class Covenant battlecruiser from Halo 1...
i hope no one ever knows that i'm crying over a mithocondria
The Creator of Human being is the most awesome Game Disainer and the most Awesome DJ.
Are we sure that Joker does exist?!
Sencillamente IMPRESIONANTE ¡¡¡
there are words in my vocabulary that can describe this in they way i want to, but it would be inappropriate. but i can say this.
THAT WAS SPECTACULAR!!!!!!!!
Wonderfull! This is the art of the nature! Who can imagine the hard and incredible proceess that Mithocondria's do?
Sorry bad english XD
If this is supposed to be a literal representation of what goes on in a a single human cell, it's pretty awesome. Like universes within universes!!! It would be helpful, however, to have some kind of narration so we can know exactly what we are looking at at any particular moment.
I would enjoy seeing a narrated version of this. As wallpaper it's very compelling, but it would be nice to understand what we're seeing.
The body is indeed a marvelous micro apparatus
Amazing video! It would be nice to have some narration though. Keep up the great work!
I thought only my school puts out videos with absolutely no descriptions or explanation of what we are looking at. Great animations, but it would be useful if there were slower transitions and you had time to take in the processes.
That is pretty sweet graphics, i wonder what type of software they used to make it?
awsome video it's very beautiful. This is very graphical for understand the biology of the cell. Very great job.
absolutely brilliant!!!!! thumps up. shows how exciting the field of biochemistry is.
This looks soo Beautiful :) of how ATP goes to ADP :D and Electrons,Ions,ect...
Thank you, great job. Wonderful presentation.
That was Brilliant.
amazing video I love biology
It looks like a machine. A bit freaky actually. But also extremely beautiful at the same time.
Note the Supported by the Howard Hughes institute at the end...these guys don't depend on government whims...the on and off faucets of conservative government (stem cell research etc.) So, they deserve our highest rating...and deepest bows.
Thanks you mother
Beautiful and imaginative uncovering. God is amazing and takes such care and pays such attention to detail.
I had a crush on biomolecular science
THIS BLEW MY MIND
I am seriously only here because I've been hunting down this video that we watched in Science class with the song "Finale" from Halo 3 is was part of the same playlist.
How can we not like it? It's my favorite too!
wonderfully made
its amazing that every part of protein can helps the cell to live.....and to form to a greater structure.... and into an social organism
I studied mitochondria and the krebs cycle and i am going ga-ga.. thank you harvard
beautiful
Thanks for the mitochondria, mom. Happy mothers day. Love you.
fark yea! love a good ATP synthase!
I took biology in higher secondary after seeing this video !!!back in 2013
@ScootleRoyale What I'm saying is that it takes a huge leap of faith to make those parallels since in the case of the electronics and machines you speak of, we know who actually created it and we can trace it back to a designer, whereas we have no way of knowing for living organisms. But we can definitely say that the theory of evolution best explains the diversity of species through studies in genetics, biochemistry, physical chemistry, organic chemistry, zoology, paleontology, etc.
Beautiful video! How close to reality are the textures and movements of the video to what we understand them to be in real life?
biology is pretty cool.
This is just our best 3d visualization, the best we have even in this age is 2d
No explaination what?
@Daniel Meyers Thanks for pointing out! ua-cam.com/video/vkYEYjintqU/v-deo.html
Wow! So good!! So good!! Cool video!!
Is there a narration to it?
Would be nice, thank you for uploading this great animation!
Rudi Metzger-Wang Hey, your profile picture is my phone’s wallpaper! That’s Endeavor against the sunset, right?
Yes there is. This is just the version so you can narwarate yourself
My G-d! There's a whole universe inside each of our cells! Awesome1
This is so awesome!