The Story of Deciphering the Ribosome - with Venki Ramakrishnan
Вставка
- Опубліковано 27 чер 2024
- Nobel Laureate Venki Ramakrishnan shares the story behind uncovering the complex structure of the ribosome and his role in the process, in conversation with Vivianne Parry.
Subscribe for regular science videos: bit.ly/RiSubscRibe
Buy Venki's book "Gene Machine": geni.us/Z4torMF
Nobel Prize winner Venki Ramakrishnan tells the story of the race to uncover the structure of the ribosome, a fundamental discovery that resolves an ancient mystery of life itself and could lead to the development of better antibiotics to fight the most deadly diseases. He will chart his unlikely journey from his first fumbling experiments in a biology lab to being at the centre of a fierce competition at the cutting edge of modern science.
Watch the Q&A: • Q&A: The Story of Deci...
Venkatraman ‘Venki’ Ramakrishnan is a Nobel Prize-winning biologist whose many scientific contributions include his work on the atomic structure of the ribosome.
Venki received the Nobel Prize in Chemistry for his work on ribosomal structure and was knighted in 2012. He is a Member of the US National Academy of Sciences, Leopoldina and EMBO, and a Foreign Member of the Indian National Science Academy. In 2015, he was elected as President of the Royal Society of London for a five-year term.
This talk was filmed at the Ri on 18 October 2018.
---
A very special thank you to our Patreon supporters who help make these videos happen, especially:
Darren Jones, Dave Ostler, David Lindo, Elizabeth Greasley, Greg Nagel, Ivan Korolev, Joe Godenzi, Lester Su, Osian Gwyn Williams, Radu Tizu, Rebecca Pan, Robert Hillier, Roger Baker, Sergei Solovev and Will Knott.
---
The Ri is on Patreon: / theroyalinstitution
and Twitter: / ri_science
and Facebook: / royalinstitution
and Tumblr: / ri-science
Our editorial policy: www.rigb.org/home/editorial-po...
Subscribe for the latest science videos: bit.ly/RiNewsletter
Product links on this page may be affiliate links which means it won't cost you any extra but we may earn a small commission if you decide to purchase through the link. - Наука та технологія
My first employment out of college was in a biomedical research lab. After maybe a year of fumbling around, I found my stride and came to be a respected member of the community. That lab structure didn't conform to a "just because you have a PhD, you're infallable" point of view. At any rate, I look back with fondness at the cooperation, camaraderie, and results we achieved. This was in the mid-80s. Primitive by today's standards. But a lot of it was bleeding edge at the time. Nice discussion in the video!
This is just about the best talk I've seen from the RI. Venki Ramakrishnan has the gift of being able to explain complex concepts and ideas in Simple English ... a rare and priceless gift. Not only that he can do it with humour and laugh at himself. A thoroughly enjoyable hour well worth watching ... and I learned a whole bunch about the Ribosome.👍👍👍😎
Even Charles Darwin made the self-deprecating remark; I was amongst the distinguished class of people who achieved second class honours, at Cambridge. He was clearly, one of the most accomplished scholars of all time who was not limited by his seeming initial prospects.
Came here to Decipher the Ribosome, got a poor interview and meandering autobiography instead.
Right. learned nothing. Book has more content. Still it's about the hows of the discoveries. Not the whats.
He is all time my inspiration ❤
Very interesting talk.
just bought the book (epub)
I got so excited after seeing the title.
... ... ...
What a disappointment. Why not prepare a full lecture, stand up, and talk.
Because she is wearing tiger skin.
Because, like BBC Radio 4's "The Life Scientific", hearing HOW a scientist got where they are and did what they've done, is interesting and in most cases inspirational.
Just amazing
I'm usually a little lukewarm about these book tour "lectures", but this one I thoroughly enjoyed.
Excellent talk regarding the history of the discovery of the ribosome and the scientist who did it. As a biologist, I am already well versed in the structure of the ribosome so this history talk was pretty interesting. If anyone here has read the "Double Helix" by watson and crick, it follows the same type of theme...a story of the history of the discovery of the structure...the ultimate structure determined while drinking beer in the Eagle Pub. I have been to the Eagle Pub on a vacation to England!
But I can understand those on here who expected a more biological/structural/function talk. But there are plenty of videos on that subject.
Hmmm. She's got the paperback version of the book, but that's not available until October.
Super . .
Since the Ribosome structure was "uncovered", has it helped anyone to explain how it works? For example, has it shed light on how it counts to 3? A Martian coming down to see what automobiles look like and move still doesn't know how they operate. The word "decipher" means more than seeing what something looks like. If you see a cuneiform document clearly, you still don't understand it until it's deciphered into a known language.
Probably wearing cheetah was not the best wardrobe choice... we’ve read his book before shooting an interview with him last week at the MRC Laboratory of Molecular Biology, Cambridge (we just published the first part). We found particularly interesting how “politics” played a role in his journey. Worth reading it. I’ve read of people complaining that there isn’t much science in this video... just Google Scholar his name... plenty of articles in Nature, Science, Cell to further explore his contribution.
20:51 "Circling the plughole is what the Americans call it"
...no...
Fascinating science, unfortunately not very much of it in this talk. I had to skip through at least half. Wish he'd have just given a lecture.
Jess B At least they get rid of the desk for these.
Yep. I don't have time for this.
Indeed
Impetus to basic science needed here in india
How do they stack ribosomes to form a crystal? how do they ensure no other items are there in that crystal? How big can be this crystal?
Those guys growing the blue crystal had better watch their six for Heisenberg.
no
Can read the book in Google books.
M K Stalin felicitated Nobel Laureate Venkataraman Ramakrishnan. Stalin hosted a grand ceremony on the scale of celebrating Ilaya Raja, Leonel, or a politician like Velu because he had never celebrated a Nobel Laureate. Nevertheless, he wanted to appreciate science in a way never attempted in Tamil Nadu by anybody or the more knowledgeable, English-speaking J Jayalalitha.
How did Venkataraman Ramakrishnan feel when a great and popular politician whose father is Kalainar or an artist in literature or litterateur par excellence felicitated him? What was the atmosphere like? What was it like being in the august and imposing presence of one of the walking colossi of Tamil Nadu politics ever since the Dravidian revolution? Was it a proud and glorious moment when a great litterateur par excellence's son himself felicitated him? How would the Hindu newspaper describe such an electrifying moment and atmosphere? Can the Hindu newspaper tell us what hung in the air? Interestingly and intriguingly, what was the audience like? What was it like being at the center of attraction of such a unique audience who were in awe of a scientist even though they have known and seen only celebrities like Illaya Raja, Lionel, or politician Velu?
Was it a God's Gift?
23:01 there´s no lens for xrays? maybe not a classical lens exactly like in a normal camera but there a hundreds of xray lenses sucensfully in use right now. in telescopes and satellites in all sizes. how does he think xray astronomy works if there were no xray lenses? it´s quite interesting actually how they work and i´m pretty sure theres a talk about it right here on this channel.
It would have been better if she was not on the stage as MC.....! I kept flashing back to scene's from Snowpiercer !!!!
High praise to have one’s presence compared with that of Tilda Swinton.
She was great in »Snowpiercer«. Hell, she was even great in »Doctor Strange«. Cheers!
Advice from Dr Venky : Do not use too many anti-biotics. And he takes atorvastatin.
Congratulations in getting a clear picture of these machines.
What's known about how a Ribosome is generated?
Articles say each of the main two subunits has RNA strings and multiple proteins.
What's the genome? Are they all expressed at one time?
What are the individual rRNA strings called? What are the bases?
How do the strings connect to proteins?
A Ribosome has a third subunit called tRNA.
We know how mRNA is made. How are tRNA subunits made? What are the bases?
Do the bases have patterns as we see in genes (translatable)?
How does a string of tRNA transport amino acid molecules?
What is the energy source?
A lot more "deciphering" is needed.
MACHINES = INTELIGENT DESIGN... nothing random
MIRACULOUSLY.... IS NOT A DARWINIAN WORD... ISNT IT?
This intreview lady has to be the most american british person
Most of the time he is talking about himself how wonderful he is.
Right ? Let us wash his feet and drink the water as they do back in his land.
@@mokujin29 Have you seen anyone to do so? Look, you are not from India. Still you haven't learnt to avoid generalized patriarchal concepts !!!
I don't want to hear about personal lives...
so read the title, and move on.
This is boring.