I visited the antimatter factory at CERN a few years ago. They have dogs at the exit who are trained to smell positrons so you don't leave with any by accident.
There was one that escaped with anti-photon. He was never seen again. At least they caught the one that made out with the gravitons, but he got a light sentence.
I was surprised there was no reference to it for 2015... Should have been easy enough to predict 🤣 Oh well it was still one of the best in every way for a time flick series. And one of the few where the sequels held up their end of the deal.
I love your digs at De Beers. Both of my parents worked for them, and my father was actually responsible for wiring and installing a lot of the diamond presses. My mom was a safe administrator, and handled the diamonds made in those very same presses. I'm really glad I've found your videos about De Beers and diamonds in general as it's shown me the truth about a company that has literally shaped part of my life, nevermind the entire country I live in.
Zolgensma is not a cure for SMA1(the form of SMA discussed in the video). It modifies the disease to be much less devastating, but the kids who were given it remain severely impaired compared to kids without SMA1. For milder forms of SMA(ones that don't kill the patient as an infant), this drug might be curative but it is too early to know.
@@toodlespoodles9842 I've got the privilege of doing the coding to get a person's insurance to accept said cost. Good news in this story was with the medical proof of SMA, it was an instant approval.
What this video doesn't explain is _why_ Zolgensma is so prohibitively expensive. Is it purely because of greed? Or is there some exceedingly time and/or resource-intensive process for creating the drug? A drug that, you know, is the difference between a baby-sized grave and somebody leading a long and fulfilling life.
@@JohnGardnerAlhadis There are other very expensive gene therapy drugs for rare conditions. The cost is mostly upfront, in the research project to understand the genetic pathway of the disease and then create and test a therapy that treats it. The rarer the disease, the more money they need to make per dose to recoup their costs. And single-dose cures are more expensive than ongoing treatments. (Trikafta, not technically a gene therapy drug though still a precision-engineered one, halts the progress of cystic fibrosis for $300K a year.) This makes it hard to figure out what a fair price actually is. Probably pretty high, but that doesn't mean they aren't still price-gouging patients. Sometimes they'll provide it free to uninsured patients, since they aren't losing any money from that.
anti-matter as a cure for cancer makes perfect sense.. the anti-matter and cancerous cells would destroy each other leaving no trace of either.. im very keen on reading more about this experimental treatment..
Tritium exit signs are incredibly rare. You're not going to see one in any cheap public business like a theater. Maybe a hospital, or some other super intense situation or government institution. If it looks "cheap", then it is indeed a $20 LED sign with a battery, and they work just fine. Even in critical applications it is very rare that a sign would need to light for more than a few minutes, it's meant to get people out and then stay out until things are fixed.
They have been less popular since the price went way up and LED signs are an appropriate technology for most uses. Also the buyer has to ship them back at the end of life, one issue is that they tend to end up in a dumpster at renovation.
I can just imagine them watching Terminator 3 or four? The one where Schwarzenegger takes his power cell out of his chest and throws it into the desert after fighting the lady Terminator
Plutonium was so scarce, thus so valuable, once some arrived at Los Alamos for the scientists to start testing with, the gold they had been testing and designing their equipment with became less valuable. How much value did the gold lose? Well, the few pound chunk of gold was relegated to becoming a doorstop for the door to the room where the plutonium was stored.
As a geologist, it wouldn’t surprise me; every rock becomes a doorstop eventually. The story at my undergrad was that one time a prof tested a doorstop that had been there forever and found that it was the (then) oldest rock ever dated.
I read a history of Hanford. I was most amazed by the fact that they invested this enormous amount of money and built a city without being sure the whole project was going to work.
Just like a couple decades later with the Apollo program, even though we didn't know if we could make it work at first, we HAD to make it work before the other guys did.
Gold has been used for an analogue in numerous different types of experiments in the nuclear weapons sector over the years. The cool part is in most cases the labs don't have to pay for what they use. They can literally borrow the gold from the US gold reserve. Obviously very careful accounting is followed to ensure the same amount withdrawn is returned, but as long as it comes back borrowing the odd ton of gold is reasonably simple within the DOE. Incidentally, the same practice was used early in the Manhattan project when a huge number of cyclotrons were built for Uranium enrichment. Rather than use copper, obviously a very important metal in wartime, the cyclotrons were built with silver wire with the silver borrowed from the US national reserves.
Gotta pay for research. Who told you kids are priceless? They are expensive! At best they are an investmemt. I'd say... The cheapest kid is at least as expensive as the costs to give birth to it. So if you feed the mother just milk and potatoes, with some foraged plants for other vitamins you could get it down to about 50k to produce one. Probably earliest before you can put them to work is six. Have them help you making shoes or soccer balls. Maybe an Asian rice farm. Only then can you start making your money back. Only by six are they start becoming worth something.
You can regenerate dim tritium exit signs by removing the tritium lamps and baking them in a high temperature oven till red hot and maintaining that for an hour. Let them cool and glue into the sign, it has about 80% the original brightness. The dimming is partly due to the decay of the tritium but mostly due to phosphor burnin. The heat regenerates the phosphor crystals but bout half the tritium is used up, but the phosphor inside doesnt need the full 15 curies to light up fully. 🤓
As someone who watched a ton of the Dark History Channel and only recently came across Simon and all his channels I have to say that I enjoy Simon's videos 10,000% more and wish teachers had been more like Simon when I was in school....
In what way? I mean I'm sure that it would be a lot of fun, I had a teacher in highschool, my 9th grade homeroom/global geography teacher, who's real actual name was Mr. Sharky. The guy was fairly non confrontational but if class got too loud he would throw a chair across the room. Everyone loved the guy, super high energy. A new student drew a cat girl in a bikini folded it into an airplane and threw it at him. The absolute legend took it, unfolded it, and pinned it up on his wall of art that he'd gotten from students and his own children over the years.
The Voyager spacecraft aren't "shuttles". They're better described as "probes". A shuttle is something that goes back and forth, like a shuttlecock or the shuttle on a weaving loom. Or a shuttle bus service between two places, like airports use. The idea of the Space Shuttle was that it would be a cheap and regular way of getting to space, and could be turned around, fixed up, once it landed, quickly and then be launched again. A shuttle, there-and-back service. It didn't work because some of the money came from the US Air Force, who ran their own, secret, missions on it. The USAF had requirements for the Shuttle to be able to deliver certain heavy payloads into polar orbit. This was past the initial remit NASA had for it. So they had to compromise, and by that I mean bodge. It's why the Solid Rocket Boosters were added, not originally part of the plan. Giant fireworks, that, once lit, burned at a certain rate, no more, no less, and unable to be throttled or otherwise controlled. Once they burned out, the Shuttle dumped them. It was a terrible idea. They were dangerous. And due to another political decision, the boosters were made in Utah. This required them to be manufactured in big long sections, rather than one solid piece, so that it would be possible to ship them to NASA's launch facilities. Being sections, meant joints between them, and that's what failed, leading to unwanted fire leaking out the side, and blowing up Challenger's fuel tank. The original design had no solid rocket boosters at all, because they're dangerous and uncontrollable. They were very much a bodge. They, and the other changes made, meant the Shuttle took much longer to turn around after landing, back into launch conidition. So launch was much more expensive. The idea of an easy, cheap, regular shuttle to space was doomed. Because the USAF put unreasonable demands on it. The original design would have been great, much safer, cheaper, and actually regular. An *actual* shuttle to space! Shame, a huge waste of money and a design that became pointless in the end. As a regular, cheap transport to space, it could have done all sorts of science and launched all sorts of payloads, that actually required a manned crew. The other heavy launch stuff the USAF wanted could have been better done on dumb, unmanned rockets. But, they built the thing, so they had to get use out of it, even though it was pointless. Maybe the Air Force jocks wanted a way to bare their arses over Moscow. A moon mission for the '80s.
The second most expensive thing after Printer Ink is Government Sourced Concrete Thing (GSCT): Doesn't matter what that thing actually is, due to the immutable laws of the universe it will be at least 4500 times more costly than exactly the same thing bought by a private person or company.
@@joesutherland225 if you think that's propaganda, just look at the F-35 program and how it completely failed to meet its objectives to the point it became the problem it was trying to solve. The program was literally the US government throwing 1.7 billion dollars in the trash
On the military industrial side I agree but on construction of infrastructure no as it is all low bid gets the job unless cronyism kicks in as has happened more than once but that's true in business too .
@@toodlespoodles9842 no it's not, the Australian government pays the difference. Price arrangements are made with pharmaceutical companies, who apply to sell their drug in Australia, and ~ $13 billion was paid the last financial year (jul20-jun21), 26 million people. There's plenty of health and drug research funded by Australia but those costs aren't passed to the consumer. There is also legislation banning end-user advertising by drug companies so they doing have the marketing costs here.
@@chlorineismyperfume In Switzerland too. Where Novartis is from... they will sell insulin for pennies to the insurance in Europe and ship the same insulin to America where a week's worth can be 100$. And the medication isn't even expensive. It's mass produced by ton. Lots of European and Asian pharma companies sell to America for much more than anyone else. Sometimes order of magnitude. Part of my healthcare research is funded by Americans being ripped off and billed thousands for a few pills or an injection.
I have a couple of contributions here: Francium and Astatine. Both are elements with no known stable isotopes with very short half-lives...and they are also both from the two most chemically reactive columns on the periodic table. Francium is an alkali metal in the same group as Sodium and Potassium, and Astatine is a halogen in the same group as Fluorine and Chlorine. Theoretically, they would react with each other extremely violently to produce Francium Astatide, if either of them could be isolated in any reasonable amounts and last long enough after isolation to even be reacted with each other. In any case, based upon current demand and tech, I'm not entirely sure that antimatter would be any more expensive than this theoretical compound.
Only problem is that they are so rare they are used for nothing. Value is what someone will pay for something, if nobody wants to buy it has no cash value.
My wife carries the SMA-1 gene, and we were fully prepared to take on a lifetime of debt if it meant our then-unborn daughter would have a full life. Thankfully, I'm not a carrier and our daughter came out happy and healthy. Still, 2 million is a small price to pay to save a child's life.
Keep in mind that in the 1800's Aluminium was as valuable as silver and approaching gold in price because it's manufacture was so difficult. One that was cracked it became commonplace. A lot of the items on this list may one day also be commonplace.
Well, the difference is that Aluminum was never rare as an element, it was just always alloyed or bonded with other elements and was difficult to purify. Many of these other substances are just flat-out rare, which is a different issue, and one much less likely to be solved.
Corection: RTG use Pu 238 which has a half-life of 87.7 years. Plutonium-238 is a very powerful alpha emitter; Because alpha particles are easily blocked, this makes the plutonium-238 isotope suitable for use in radioisotope thermoelectric generators and radioisotope heaters. Pure plutonium-238 is prepared by neutron irradiation of neptunium-237 or by the neutron irradiation of americium in a reactor. It can not be used in nuclear device. Weapon grade Pu 239 is reactor-bred by exposure of U 238 to neutron flux for a limited time and it has to have 3-7 % Pu 240 to be used in device because Pu 240 will cause predetonation and result in fizzle. Supergrade Pu 239 has less than 3% Pu 240.
Tritium near certainly finds its largest use in certain discharge lamps - it is used as a starter - by decaying it produces electrons to start electrical discharge.
Not exactly my field but the Tritium signs are probably close to break even considering the cost of installation and maintenance for traditional emergency lights and battery banks. The batteries are going to need replacing probably every 5 years. However, there are so many other things in a modern building that will require the back up power you might as well just go with regular signage.
German health insurance also has covered the cost of treatment with Zolgensma, but the parents had to sue first, which was of course nerve-wracking as the drug will not be given after the child is two years old. So it is a battle against time. The parents won though. :-)
@@01oo011 Omg thank you, I was binge watching WhistlerVerse after a weeks holiday and I thought i'd just tripped out a whole episode that wasn't actually there.
I have a English built battle sight SUIT (Sight Unit Infantry Trilux) made in 1976! I had the tritium element replaced for $US 125.00. The life expectancy on the element states a half life of 7 years. Love the green glow that is really visible from dawn to dusk and very cloudy days! Best of all no batteries with their weight, short life,loss of capacity at low temperatures and fragility! Really enjoy your programs and their information value and entertainment!
This goes back a decade or so, I haven't had to price it in a while, but thrombolytics such as TPA used as clot busters. That will break up clots that are responsible for embolism strokes, and pulmonary embolism. Which usually require 1 injection, went for somewhere near $15,000 a dose. It does come with side effects, such as turning an embolism stroke, into a hemorrhagic stroke with poorer out comes. If you're facing the devastating effects of a stroke ... will you take the chance
@@UnicornsPoopRainbows I believe it's expensive everywhere, due to 1 manufacturer and what it does. Here's the thing there's a shit load of misconceptions about American medicine and it's cost m, that are just untrue. Same goes for American prices. If you need it you get it ... no matter your ability to pay or not. Its unethical, and actually illegal to with hold life saving treatment because of I ability to pay. You can show up at out ER doors, homeless and destitute. If you need to be taken care of, needing surgery or in this case theombolytics ... you get it. One reason US Healthcare is expensive, people don't use their primary care Dr's ans wait until its too late, and head to the ER ... which is always going to cost more. Prices for aspirin will be high, because the hospital has added 2 more Cat Scanners at 1 million a pop, in order to get as many patients life saving diagnostics in a timely fashion. If you have 2 different patients who are having a stroke ... and time is of the essence as you has a short window to give thrombolytics. If you already have 1 in the CT scanner, the 2nd had to wait. If you have 2 scanners, now both can get scanned quickly. If you have 3 now you can get the guy in the car accident in as well. So those prices are paying for the equipment, the techs, nurses and the Dr's The Electric to run the machines, the malpractice insurance that covers the hospital and all the employees in it. Except usually the Dr's who carry their own. As they're contractors to the hospital, not employees of it. Neurosurgeons can pay 1 million a year in malpractice. OB-Gyns malpractice pract. Is expensive as hell too. Bottom line, you walk in. You need treatment you get it. No one is refusing your care of you can't pay. Hospital also have to do a percentage of indigent care a yr to keep the ability to get Medicare Medicaid dollars. My hospital in was well over 250 million a year in free Healthcare. No one will take your house, garnish wages nothing. You can set up a payment for $5/mo. There are programs, if you make less than something like 50K year or have kids that will pay the bills. There are county clinics that you can get primary dr and see any and all specialist for $20 .... people won't use them. So they go to ERs where it costs more. I talked about hospitals putting in more CT scanners. In countries with universal Healthcare. They won't add new scanners, people just wait. With a stroke... if you have to wait more than 4 hours, you can't use theomolytics. But it's free. You won't get Dr's in the US to work for what they get paid in the UK ... first foremost they're still paying down their student loans for med school. Second, they'll take their smarts and go to where the money is. That's what's happening with primary care Dr in US. There's a shortage, because they're all going into specialties. Why .... $ I can talk this all day. I've worked in both types of systems. And from seeing one run by the state ... you don't want it. I've seen 24-36 hour waits in the waiting room. Why because they had to do tge keast expensive test possible and get tge results back before moving to the next expensive test and so on They're difficult to sue if they screw up or it's capped at like 50K ... It's called Sovereign Immunity
Soliris is an incredibly expensive drug. While it's not nearly as expensive as the drug mentioned in the video it's not a cure so it has to be taken regularly and it can cost upwards of $450,000 per year. Luckily, it is considered an "orphan drug" so it's cost is usually covered. Or else, no one could ever possibly utilize it.
exactly why Zolgensma is honestly the better option in the long run, at least from a cost standpoint. You'll spend more on Soliris in less than 5 years, but that one dose of Zolgensma will halt SMA-1's progression entirely.
@@OGA103 sorry i thought you were referring to the other treatment there is for SMA-1, i was thinking of Spinraza. Spinraza costs between $625,000 and $750,000 for the first year of treatment and then $375,000 a year for the rest of the patient's life.
One of ny sons cystic fibrosis meds was £350000 a year until it was made free, and another one he has once a day is be about £15000 a year. Meds shouldn't cost this much for anybody.
@@bmstylee it costs billions of dollars to bring a drug to market - and that is those that actually make it all the way to approval. so many never make it that far, so they lose billions on all the research and development and time lost on those that never go to market. i do think that meds are overcharged, but there's a lot that goes on behind the scenes that nobody takes into account either.
I have no issues with making a profit. But what some of those companies charge for meds is outrageous. I guess you guys are happy knowing they make billions in profit while many people have to choose between having meds or putting food on the table.
@@bmstylee literally never said that. i said that med costs are ridiculous, especially for established meds outside of their patent (e.g. epipens). but yes. with the new wave of cell and gene therapies that are either tailored to the individual patient (sometimes even using their own blood) or are for conditions so rare, companies will never really recoup costs or if they do it will take decades. however, these orphan drugs are needed for those with rare disorders or they’ll just keep on ignoring them since there’s no profit to be made there. that’s why they need to profit elsewhere, to make those other treatments possible.
Someone tried quark rustling at CERN. They turned on the charm, and went up and down, but then things turned strange. The top and bottom of it was that some boson called Higgs positively negated their scheme when they were photoned making a quantum leap. They were dicharged and had to turn over a neutrino before they were let out of containment. The atmosphere was electric until the gravity of their situation hit them. The alternative would have been a strong spin for a weak in the collider.
I'd like to watch a video entirely dedicated to Plutonium batteries (and other sorts of batteries that don't run on the chemical reaction between metal and acids).
4:02 that 87.7 year half life is for Pu-238, which is used in thermal power supplies (e.g. for long-haul space probes), the kind used for nukes, Pu-239, has a half life of 24,100 years.
11:43 As an author, the more I learn about anti-matter the more I want to learn. Anti-matter engines, anti-matter control chips, anti-matter mining.....the possibilities are endless
Mrs Richards: "I paid for a room with a view !" Basil: (pointing to the lovely view) "That is Torquay, Madam ." Mrs Richards: "It's not good enough!" Basil: "May I ask what you were expecting to see out of a Torquay hotel bedroom window? Sydney Opera House, perhaps? the Hanging Gardens of Babylon? Herds of wildebeest sweeping majestically past?..." Mrs Richards: "Don't be silly! I expect to be able to see the sea!" Basil: "You can see the sea, it's over there between the land and the sky." Mrs Richards: "I'm not satisfied. But I shall stay. But I expect a reduction." Basil: "Why?! Because Krakatoa's not erupting at the moment ?"
3:04 , well, I'll just say that this is somewhat of a misconception. You can actually get your hands on Plutonium quite easily. And it's legal, under a certain amount/weight. It's incredibly small in terms of amounts, but it's still enough to know for a fact that it's there. It's just that most sources available to normal people are from old smoke detectors called the RID-1 and the RID-6M, which are legal to own in the US. There may be a few others out there, but you can indeed get Plutonium out of them in the form of their ion sources. The 6M's are the most popular (and cheapest, at least in the states) and can even be bought on popular selling sites like ebay. I actually have like 8 of the 6M's and can easily detect them with my Geiger counter. Same can be said about Uranium. I have several ounces of the metal, as well as some granular chunks of Thorium metal. I can also get things like Actinium Sulfate, Technetium metal plated on a strip of foil like from the Periodic Videos YT video on it, etc. Another cool one is heavy water, or Deuterium Oxide. It has Deuterium as the Hydrogens in the water and it's the middle isotope between Hydrogen and Tritium. Though it's not radioactive. Again, this is all legal as long as you keep your samples under a certain amount of the materials. Now, anything weapons grade is illegal. But none of these samples are the isotopes that are illegal or even used for war.
Looking at the UK guidelines briefly it seems to be broadly similar to normal explosives. The material e.g high explosives doesn't seem to be the problem, its more that you are storing it safely, that its not a risk to others, and that the fire services know exactly where it is. But obviously they aren't going to give a licence to a terrorist, but a terrorist probably wouldn't be stupid enough to apply for one either!
@@Darth-Claw-Killflex not all do, the ones with tritium cost around $300-400. If they are used the glow is pretty dim and you can buy them for less than that
i knew Zolgensma would be on this list as the most expensive pharmaceutical in the world. my company handled the transportation of the drug while it was in development and also handles global distribution for all doses now that it is in commercial production. it's truly amazing the possibilities there are with these new gene therapies to replace faulty genes causing genetic disorders like SMA-1 and effectively curing them.
@@firstmkb haha no but then again it's not like it's something that has much in the way of street value and it's not like people would know what was in the vehicle like armored trucks carrying money or whatever would.
Tritium: As a "Federally registered Nuclear radiation worker" In Canada, I have witnessed personally, Ontario Hydro workers, using tiny suction bottles picking up Tritium out of cracks in the concrete after a spill ...
Tritium does not glow, it is a phosphor coating on the glass that glows when hit by alpha particles. Plutonium is made by hitting Uranium 238 with neutrons, not deuterium!
funny thing about the plutonium in BTTF is that it's shown as a red liquid (not green at least i suppose...) rather than a grey solid . Didn't realise emergency signs used radioactive material though, but makes sense when you think about it
What exactly do you mean by there not being any money in it? For what reason? If because the power would be too cheap, then that's the same kind of nonsense as claims that pharma doesn't want to cure anything because that would eliminate the market.
Apparently the sentiment is more apathy, dealing with activists / protests and realising the misinformation about radiation is embedded in many populations means they've struggled to get public, and therefore government support. Def in Australia anyway, which is a shame.
30000 bucks a gram? So, why aren't the Japanese extracting the stuff from the cooling water in Fukushima Daiichi? Oh right, it's so little that it's not worth it, and won't do any environmental damage if diluted further.
Zolgensma cures a very rare disease so it makes sense to be expensive with the low number of dossis sold and the required research. Insulin is quite cheap to produce, the costs of its research and development are already paid in full many times over. It's the combination of an inefficient healthcare system and crooked morals by big pharma what makes it so expensive. So yeah, not really the same.
@@andiward7068 I have had mine for 14 years. But just got a new one a month ago that has like a wifi thing that transmits all the info. But yeah I would have to go every 6 months and the rep would put this halo thing over the pacemaker and press buttons and play God. Lol yeah its weird. I got the pacemaker at 27 years old. Crazy times
@@mattpaul5441 Mine is pm/defib. I've got the wifi box too but I need to connect it. I prefer going in person because they can tell me what was going on but w/the box I'll only know if it's something major. It's a mental thing, I'm working on it. I was 38 but still youngest recipient at that hsp. Yay us! Early adopters unite.
@@mattpaul5441luckily it's never gone off. My function was nearly normal in hsp before the implant and it was debatable if I really needed it. Drs decided to err on the side of "jic". (Idiopathic CHF.)
you can actually harvest antimatter in the same way you produce xrays. lightning for instance creates antimatter - we know this from satellite observations. so the price per gram is actually very far from optimal. i would imagine antimatter could be scarry cheap in the near future.
I actually heard about this drug. The company that makes it says that insurance nearly always covers it. It pretty much is *the* definition of "medically necessary". The one issue is that treatment does sometimes require more than 1 dose. Insurance company bureaucrat: "And what happens if the kid doesn't get this?" Doctor: "The kid dies." Insurance company bureaucrat: "And how likely is that?" Doctor: "Just about 100%." Bureaucrat: "Ok."
I thought it best to point out emergency exit signs are required by code (building and fire) to work for "at least 8hrs", and they're required to be tested periodically. (when moving into new office space, we can't get a certificate of occupancy without them being power-out tested for 8 hours.) Thus, those LED based signs will work for hours; probably many more hours than they ever need to. (when the power is out, I usually leave within 8 hours.)
Probably doesn't cost much to make; that's irrelevant. How much was spent on developing it - that's where the cost is. It's not like a regular Joe stumbled across it by accident. Scientists aren't cheap!
@@dennishilmas3423 yep, and of course that's the problem with such medicines. Firstly this is an incredibly rare disease, a couple of thousand patients a year globally. The drug would have cost hundreds of millions to develop. Unlike, say, a flu vaccine, which will be sold in hundreds of millions of doses, this drug will be sold in its tens of doses. Now I am not one for forgiving drugs companies, some of their practices are disgusting, but the reality is that such drugs need money to develop them and in order to raise the money a return on the investment is needed. It would help the drug company 's causes if they were transparent on their profit margins. The answer to funding these doses is in the funding of treatment. Models to raise the funds to treat sick children are where the focus needs to be and Novartis say, subsidising the cost of such funded doses rather than a 'lottery 'would be more egalitarian and also fairer.
8:40 I wouldn't say any parent, you have way too much faith in humanity. It's far cheaper to just let it die and start over and try again, a pregnancy and raising a kid to a year old while waiting for it to die only costs about 1% as much, about $21k.
@@Anonymous-df8it Only if the cops find out about it. Home birth + mother stays home the whole 9 months = no one will even be aware anyone was killed or missing. It happens more often than you think. And that's for outright murder/manslaughter. Letting nature do it because you can't afford to prevent it = nope, not the parent's' fault so no charges if nature does it. In the US 3 people a minute die 24/7 due to not being able to afford health care or some overpriced treatment.
The Russians and I should think a lot of large companies use those plutonium generators from voyager for radio controlled operations in areas where power lines couldnt get to. This is a pretty similar use as the voyagers. Uses included dam gates operation and signal repeaters or communications towers to power radio equipment and linear amplifiers for amplifying radio signals over very large spaces. As for antimatter it is used in medicine all the time. They use it for P.E.T. scans hence the P for positron the antimatter equivalent of an electron. Really makes me mad when people moan about CERN creating antimatter as it is done a lot in nuclear medicine . It is very very hard though to produce whole atoms of antimatter and CERN are doing that but the parts of an atomic structure frequently decay and when this happens we get anti matter particles that last less than a nanosecond being emitted as part of atomic decay. They call antimatter in a sizeable amount anti matter rice . They have not made that much yet but thats what they call it.
The batteries last 90 min on exist signs. And should be replaced about every two years. You can test them with a button by the little green or red led on the side or bottom.
I visited the antimatter factory at CERN a few years ago. They have dogs at the exit who are trained to smell positrons so you don't leave with any by accident.
Underrated comment
I heard you could sneak past them by telling the guards they're actually electrons, then walking backwards through the exit.
There was one that escaped with anti-photon. He was never seen again.
At least they caught the one that made out with the gravitons, but he got a light sentence.
@@rsrt6910 probably the best comment
thats really cool actually
"I'm sure that in 1985, plutonium is available in every corner drugstore, but in 1955, it's a little hard to come by." -- Dr. Emmett Brown
I was surprised there was no reference to it for 2015... Should have been easy enough to predict 🤣
Oh well it was still one of the best in every way for a time flick series. And one of the few where the sequels held up their end of the deal.
I wanna push the thumbs up but it's at 88....mph? 🙂
I love your digs at De Beers. Both of my parents worked for them, and my father was actually responsible for wiring and installing a lot of the diamond presses. My mom was a safe administrator, and handled the diamonds made in those very same presses. I'm really glad I've found your videos about De Beers and diamonds in general as it's shown me the truth about a company that has literally shaped part of my life, nevermind the entire country I live in.
@Whatsap±1707𝟽𝟸𝟸𝟶𝟹60 Sideprojects scammer channel
Your parents were parent of one of the worlds biggest monopolies
So DeBeers makes its diamonds? I thought they only mined diamonds…
@@billhaviland4380 they have both mining and synthetic operations. It's extremely interesting.
EVILCOMPANY
Dude you have like 20 damn channels. You're grind is unmatched. Much respect man.
0:40 - Chapter 1 - Tritium
3:05 - Chapter 2 - Plutonium
5:50 - Chapter 3 - Taaffeite
8:15 - Chapter 4 - Zolgensma
10:30 - Chapter 5 - Anti matter
you da real mvp
Thank You Very Much 😋😋
The hero we need but don’t deserve.
Ty
Thank you!
Printer ink is actually the most expensive material.
Truth
@E Van That helps for sure
Black gold
Apparently you can buy a gram of printer ink for just 400 tonnes of HP printers.
Agreed
Zolgensma is not a cure for SMA1(the form of SMA discussed in the video). It modifies the disease to be much less devastating, but the kids who were given it remain severely impaired compared to kids without SMA1. For milder forms of SMA(ones that don't kill the patient as an infant), this drug might be curative but it is too early to know.
I’ve prepared doses for a few patients. When I’ve informed my coworkers the price, fortunately only their jaws dropped 🤣
@@toodlespoodles9842 I know all to well how expensive some medications can be, one of the things I take is about 150k a gram 😭
@@toodlespoodles9842 I've got the privilege of doing the coding to get a person's insurance to accept said cost.
Good news in this story was with the medical proof of SMA, it was an instant approval.
What this video doesn't explain is _why_ Zolgensma is so prohibitively expensive. Is it purely because of greed? Or is there some exceedingly time and/or resource-intensive process for creating the drug? A drug that, you know, is the difference between a baby-sized grave and somebody leading a long and fulfilling life.
@@JohnGardnerAlhadis There are other very expensive gene therapy drugs for rare conditions. The cost is mostly upfront, in the research project to understand the genetic pathway of the disease and then create and test a therapy that treats it. The rarer the disease, the more money they need to make per dose to recoup their costs. And single-dose cures are more expensive than ongoing treatments. (Trikafta, not technically a gene therapy drug though still a precision-engineered one, halts the progress of cystic fibrosis for $300K a year.)
This makes it hard to figure out what a fair price actually is. Probably pretty high, but that doesn't mean they aren't still price-gouging patients. Sometimes they'll provide it free to uninsured patients, since they aren't losing any money from that.
anti-matter as a cure for cancer makes perfect sense..
the anti-matter and cancerous cells would destroy each other leaving no trace of either..
im very keen on reading more about this experimental treatment..
My day would not be complete without watching Simon's great videos, thanks guys.
Thanks :)
Tritium exit signs are incredibly rare. You're not going to see one in any cheap public business like a theater. Maybe a hospital, or some other super intense situation or government institution. If it looks "cheap", then it is indeed a $20 LED sign with a battery, and they work just fine.
Even in critical applications it is very rare that a sign would need to light for more than a few minutes, it's meant to get people out and then stay out until things are fixed.
They have been less popular since the price went way up and LED signs are an appropriate technology for most uses. Also the buyer has to ship them back at the end of life, one issue is that they tend to end up in a dumpster at renovation.
Zolgensma is covered in Poland too. They recently added it to funded list.
"What the hell is antimatter?"
"doesn't matter."
So there's still half a dozen people walking around who can honestly boast they're nuclear powered?!😁🤣
I can just imagine them watching Terminator 3 or four? The one where Schwarzenegger takes his power cell out of his chest and throws it into the desert after fighting the lady Terminator
Not powered but regulated
@@wingerding It's a _joke_
Nuclear regulated grandma
Plutonium was so scarce, thus so valuable, once some arrived at Los Alamos for the scientists to start testing with, the gold they had been testing and designing their equipment with became less valuable. How much value did the gold lose? Well, the few pound chunk of gold was relegated to becoming a doorstop for the door to the room where the plutonium was stored.
As a geologist, it wouldn’t surprise me; every rock becomes a doorstop eventually. The story at my undergrad was that one time a prof tested a doorstop that had been there forever and found that it was the (then) oldest rock ever dated.
Nowhere near the same level, but at a lab I worked at the boss had a silver ingot he used as a door stop.
I read a history of Hanford. I was most amazed by the fact that they invested this enormous amount of money and built a city without being sure the whole project was going to work.
Just like a couple decades later with the Apollo program, even though we didn't know if we could make it work at first, we HAD to make it work before the other guys did.
Gold has been used for an analogue in numerous different types of experiments in the nuclear weapons sector over the years. The cool part is in most cases the labs don't have to pay for what they use. They can literally borrow the gold from the US gold reserve. Obviously very careful accounting is followed to ensure the same amount withdrawn is returned, but as long as it comes back borrowing the odd ton of gold is reasonably simple within the DOE.
Incidentally, the same practice was used early in the Manhattan project when a huge number of cyclotrons were built for Uranium enrichment. Rather than use copper, obviously a very important metal in wartime, the cyclotrons were built with silver wire with the silver borrowed from the US national reserves.
Now, every parent would tell you that you can't put a price on a child's life, but this pharmaceutical company disagrees" this is perfect 🙏
All pharmaceutical companies disagree
@@ferrusmanus184 Well, the company either charges enough to make up for their costs, or the medicine doesn't get made, so...
Nothing but Devils and when they find a cure for cancer it will only be for the rich..
Gotta pay for research.
Who told you kids are priceless? They are expensive! At best they are an investmemt.
I'd say... The cheapest kid is at least as expensive as the costs to give birth to it. So if you feed the mother just milk and potatoes, with some foraged plants for other vitamins you could get it down to about 50k to produce one.
Probably earliest before you can put them to work is six. Have them help you making shoes or soccer balls. Maybe an Asian rice farm.
Only then can you start making your money back. Only by six are they start becoming worth something.
Every parent: “You cannot put a price on a child’s life!”
Unless you put life insurance on the child…
You can regenerate dim tritium exit signs by removing the tritium lamps and baking them in a high temperature oven till red hot and maintaining that for an hour. Let them cool and glue into the sign, it has about 80% the original brightness. The dimming is partly due to the decay of the tritium but mostly due to phosphor burnin. The heat regenerates the phosphor crystals but bout half the tritium is used up, but the phosphor inside doesnt need the full 15 curies to light up fully. 🤓
Makes sense. The first thing to go would naturally be the phosphors.
As someone who watched a ton of the Dark History Channel and only recently came across Simon and all his channels I have to say that I enjoy Simon's videos 10,000% more and wish teachers had been more like Simon when I was in school....
In what way? I mean I'm sure that it would be a lot of fun, I had a teacher in highschool, my 9th grade homeroom/global geography teacher, who's real actual name was Mr. Sharky. The guy was fairly non confrontational but if class got too loud he would throw a chair across the room. Everyone loved the guy, super high energy. A new student drew a cat girl in a bikini folded it into an airplane and threw it at him. The absolute legend took it, unfolded it, and pinned it up on his wall of art that he'd gotten from students and his own children over the years.
@@atashgallagher5139 I have ADHD so how Simon will go on tangents and other things helps keep me focused and engaged
what by showing you an ad every 2 minutes?
Dark History as in Bailey Sarian? I mean, I love Simon - but he's no Bailey 😂😂😂
The Voyager spacecraft aren't "shuttles". They're better described as "probes". A shuttle is something that goes back and forth, like a shuttlecock or the shuttle on a weaving loom. Or a shuttle bus service between two places, like airports use.
The idea of the Space Shuttle was that it would be a cheap and regular way of getting to space, and could be turned around, fixed up, once it landed, quickly and then be launched again. A shuttle, there-and-back service. It didn't work because some of the money came from the US Air Force, who ran their own, secret, missions on it. The USAF had requirements for the Shuttle to be able to deliver certain heavy payloads into polar orbit. This was past the initial remit NASA had for it.
So they had to compromise, and by that I mean bodge. It's why the Solid Rocket Boosters were added, not originally part of the plan. Giant fireworks, that, once lit, burned at a certain rate, no more, no less, and unable to be throttled or otherwise controlled. Once they burned out, the Shuttle dumped them.
It was a terrible idea. They were dangerous. And due to another political decision, the boosters were made in Utah. This required them to be manufactured in big long sections, rather than one solid piece, so that it would be possible to ship them to NASA's launch facilities. Being sections, meant joints between them, and that's what failed, leading to unwanted fire leaking out the side, and blowing up Challenger's fuel tank.
The original design had no solid rocket boosters at all, because they're dangerous and uncontrollable. They were very much a bodge. They, and the other changes made, meant the Shuttle took much longer to turn around after landing, back into launch conidition. So launch was much more expensive. The idea of an easy, cheap, regular shuttle to space was doomed. Because the USAF put unreasonable demands on it. The original design would have been great, much safer, cheaper, and actually regular. An *actual* shuttle to space!
Shame, a huge waste of money and a design that became pointless in the end. As a regular, cheap transport to space, it could have done all sorts of science and launched all sorts of payloads, that actually required a manned crew. The other heavy launch stuff the USAF wanted could have been better done on dumb, unmanned rockets. But, they built the thing, so they had to get use out of it, even though it was pointless. Maybe the Air Force jocks wanted a way to bare their arses over Moscow. A moon mission for the '80s.
The second most expensive thing after Printer Ink is Government Sourced Concrete Thing (GSCT): Doesn't matter what that thing actually is, due to the immutable laws of the universe it will be at least 4500 times more costly than exactly the same thing bought by a private person or company.
that's cuz every friend of the government needs to take a cut to make/produce said thing .
Propaganda
And will take 50x longer to complete
@@joesutherland225 if you think that's propaganda, just look at the F-35 program and how it completely failed to meet its objectives to the point it became the problem it was trying to solve. The program was literally the US government throwing 1.7 billion dollars in the trash
On the military industrial side I agree but on construction of infrastructure no as it is all low bid gets the job unless cronyism kicks in as has happened more than once but that's true in business too .
My daughter has been treated with Zolgensma and your explanation for those who may not have any medical knowledge is fantastic
How rich are you?
@@Anonymous-df8it It's free in the UK
@@grantrimmell9005 How do you know where she lives?
@@Anonymous-df8it it's also free in Australia.
LOVED the casual remark to De Beers!
zolgensma is also covered in Australia :) apparently It only costs $42.50 (with the rest covered), or $6.80 for people with concession cards.
And that’s why the price is higher elsewhere so company can recoup research costs
@@toodlespoodles9842 More likely the government is buying at market price and the $42 is the copay
Don't confuse what the patient pays with the cost.
@@toodlespoodles9842 no it's not, the Australian government pays the difference. Price arrangements are made with pharmaceutical companies, who apply to sell their drug in Australia, and ~ $13 billion was paid the last financial year (jul20-jun21), 26 million people. There's plenty of health and drug research funded by Australia but those costs aren't passed to the consumer. There is also legislation banning end-user advertising by drug companies so they doing have the marketing costs here.
@@chlorineismyperfume In Switzerland too. Where Novartis is from... they will sell insulin for pennies to the insurance in Europe and ship the same insulin to America where a week's worth can be 100$. And the medication isn't even expensive. It's mass produced by ton. Lots of European and Asian pharma companies sell to America for much more than anyone else. Sometimes order of magnitude. Part of my healthcare research is funded by Americans being ripped off and billed thousands for a few pills or an injection.
The first time I learned of Tritium was as an army cadet getting to handle the SA80 and being told the SUSAT is radioactive.
I have a couple of contributions here: Francium and Astatine. Both are elements with no known stable isotopes with very short half-lives...and they are also both from the two most chemically reactive columns on the periodic table. Francium is an alkali metal in the same group as Sodium and Potassium, and Astatine is a halogen in the same group as Fluorine and Chlorine. Theoretically, they would react with each other extremely violently to produce Francium Astatide, if either of them could be isolated in any reasonable amounts and last long enough after isolation to even be reacted with each other. In any case, based upon current demand and tech, I'm not entirely sure that antimatter would be any more expensive than this theoretical compound.
Only problem is that they are so rare they are used for nothing. Value is what someone will pay for something, if nobody wants to buy it has no cash value.
@@michaelkirchner8379 If Astatine weren't so rare, it would have uses in medical imaging.
The big problem is if you have enough of either of them in one place, the heat from their nuclear decay is going to instantly vaporize them.
My wife carries the SMA-1 gene, and we were fully prepared to take on a lifetime of debt if it meant our then-unborn daughter would have a full life. Thankfully, I'm not a carrier and our daughter came out happy and healthy. Still, 2 million is a small price to pay to save a child's life.
Or just adopt. Not very responsible to produce a child when there is a large possibility of big negative health affects or extreme expenses.
Every time I tell my fiancee about the things I learned on this channel, she's like "alright, thats enough...take off your clothes" 😆😆 thankyouuuuu
As she laughs and runs off with her ‘side project’ 😉🦸♂️
@10:54
Me: eats banana
Me: "I run on anti-matter"
Since today Poland will also cover the cost of Zolgensma and other SMA drugs
Keep in mind that in the 1800's Aluminium was as valuable as silver and approaching gold in price because it's manufacture was so difficult. One that was cracked it became commonplace. A lot of the items on this list may one day also be commonplace.
Well, the difference is that Aluminum was never rare as an element, it was just always alloyed or bonded with other elements and was difficult to purify. Many of these other substances are just flat-out rare, which is a different issue, and one much less likely to be solved.
Can we all take a moment to recognise Simons absolute hatchet job of pronouncing Tanzania 😂
I noticed that, but I'm far too polite to post...wait a minute, no I'm not. 🙂
Corection: RTG use Pu 238 which has a half-life of 87.7 years. Plutonium-238 is a very powerful alpha emitter; Because alpha particles are easily blocked, this makes the plutonium-238 isotope suitable for use in radioisotope thermoelectric generators and radioisotope heaters. Pure plutonium-238 is prepared by neutron irradiation of neptunium-237 or by the neutron irradiation of americium in a reactor. It can not be used in nuclear device.
Weapon grade Pu 239 is reactor-bred by exposure of U 238 to neutron flux for a limited time and it has to have 3-7 % Pu 240 to be used in device because Pu 240 will cause predetonation and result in fizzle. Supergrade Pu 239 has less than 3% Pu 240.
"Jusy eat more bananas, that's how it works, right?" 🤣🤣🤣
Tritium near certainly finds its largest use in certain discharge lamps - it is used as a starter - by decaying it produces electrons to start electrical discharge.
Zolgensma is actually free in our contry, our universal healthcare program fully covers the 2,1 millions dollars cost. (Canada)
Not exactly my field but the Tritium signs are probably close to break even considering the cost of installation and maintenance for traditional emergency lights and battery banks. The batteries are going to need replacing probably every 5 years. However, there are so many other things in a modern building that will require the back up power you might as well just go with regular signage.
German health insurance also has covered the cost of treatment with Zolgensma, but the parents had to sue first, which was of course nerve-wracking as the drug will not be given after the child is two years old. So it is a battle against time. The parents won though. :-)
I swear one of your channels was talking about tritium recently... am I hallucinating.
You’re not crazy, it’s called unusual isotopes or something on Top10s.
@@01oo011 Omg thank you, I was binge watching WhistlerVerse after a weeks holiday and I thought i'd just tripped out a whole episode that wasn't actually there.
I thought for sure we would see horseshoe crab blood on this. Supposedly the most expensive liquid in the world or something like that.
I heard that mouse milk is expensive also. Needed for experiments.
I have a English built battle sight SUIT (Sight Unit Infantry Trilux) made in 1976! I had the tritium element replaced for $US 125.00. The life expectancy on the element states a half life of 7 years. Love the green glow that is really visible from dawn to dusk and very cloudy days! Best of all no batteries with their weight, short life,loss of capacity at low temperatures and fragility! Really enjoy your programs and their information value and entertainment!
Woman skin care and beauty products are #1. Saved you all the view.
Loving the pronunciation of Tanzania, which is the way I have always pronounced it. It’s wrong, but thank you for being my pronunciation twin Simon.
because if the power goes out in a building I want to have at least 12 years to get out.
Outside of a nuclear meltdown, the yearly radiation exposure of a power plant worker is less than the radiation absorbed from eating a banana.
This goes back a decade or so, I haven't had to price it in a while, but thrombolytics such as TPA used as clot busters. That will break up clots that are responsible for embolism strokes, and pulmonary embolism. Which usually require 1 injection, went for somewhere near $15,000 a dose.
It does come with side effects, such as turning an embolism stroke, into a hemorrhagic stroke with poorer out comes. If you're facing the devastating effects of a stroke ... will you take the chance
Is that American prices or Rest of the World prices?
@@UnicornsPoopRainbows
I believe it's expensive everywhere, due to 1 manufacturer and what it does.
Here's the thing there's a shit load of misconceptions about American medicine and it's cost m, that are just untrue. Same goes for
American prices.
If you need it you get it ... no matter your ability to pay or not. Its unethical, and actually illegal to with hold life saving treatment because of I ability to pay.
You can show up at out ER doors, homeless and destitute. If you need to be taken care of, needing surgery or in this case theombolytics ... you get it.
One reason US Healthcare is expensive, people don't use their primary care Dr's ans wait until its too late, and head to the ER ... which is always going to cost more. Prices for aspirin will be high, because the hospital has added 2 more Cat Scanners at 1 million a pop, in order to get as many patients life saving diagnostics in a timely fashion. If you have 2 different patients who are having a stroke ... and time is of the essence as you has a short window to give thrombolytics. If you already have 1 in the CT scanner, the 2nd had to wait. If you have 2 scanners, now both can get scanned quickly. If you have 3 now you can get the guy in the car accident in as well.
So those prices are paying for the equipment, the techs, nurses and the Dr's
The Electric to run the machines, the malpractice insurance that covers the hospital and all the employees in it. Except usually the Dr's who carry their own. As they're contractors to the hospital, not employees of it. Neurosurgeons can pay
1 million a year in malpractice. OB-Gyns malpractice pract. Is expensive as hell too.
Bottom line, you walk in. You need treatment you get it. No one is refusing your care of you can't pay. Hospital also have to do a percentage of indigent care a yr to keep the ability to get Medicare Medicaid dollars. My hospital in was well over 250 million a year in free Healthcare.
No one will take your house, garnish wages nothing. You can set up a payment for $5/mo.
There are programs, if you make less than something like 50K year or have kids that will pay the bills.
There are county clinics that you can get primary dr and see any and all specialist for $20 .... people won't use them. So they go to ERs where it costs more.
I talked about hospitals putting in more CT scanners. In countries with universal Healthcare. They won't add new scanners, people just wait.
With a stroke... if you have to wait more than 4 hours, you can't use theomolytics. But it's free.
You won't get Dr's in the US to work for what they get paid in the UK ... first foremost they're still paying down their student loans for med school. Second, they'll take their smarts and go to where the money is. That's what's happening with primary care Dr in US. There's a shortage, because they're all going into specialties. Why .... $
I can talk this all day. I've worked in both types of systems. And from seeing one run by the state ... you don't want it. I've seen 24-36 hour waits in the waiting room. Why because they had to do tge keast expensive test possible and get tge results back before moving to the next expensive test and so on
They're difficult to sue if they screw up or it's capped at like 50K ... It's called Sovereign Immunity
Simon: Extra care needs to be taken when handling the hazardous substance Tritium.
Me: Pins tritium vial to the end of a magnum revolver...
Calcium 48 would have been a good candidate on that list at $250K/gram
Soliris is an incredibly expensive drug. While it's not nearly as expensive as the drug mentioned in the video it's not a cure so it has to be taken regularly and it can cost upwards of $450,000 per year. Luckily, it is considered an "orphan drug" so it's cost is usually covered. Or else, no one could ever possibly utilize it.
That explains why the all the TV ads are telling me to ask my doctor about it.
exactly why Zolgensma is honestly the better option in the long run, at least from a cost standpoint. You'll spend more on Soliris in less than 5 years, but that one dose of Zolgensma will halt SMA-1's progression entirely.
@@alexismonetti well the fact that these two meds treat completely different diseases make the cost comparison look like apples and oranges anyways.
@@OGA103 sorry i thought you were referring to the other treatment there is for SMA-1, i was thinking of Spinraza. Spinraza costs between $625,000 and $750,000 for the first year of treatment and then $375,000 a year for the rest of the patient's life.
@@alexismonetti yiiikes.
Was surprised that horseshoe crab blood didn't make the list, cos i know that's hella expensive too
Hen’s Teeth are the rarest thing in the known universe.
One of ny sons cystic fibrosis meds was £350000 a year until it was made free, and another one he has once a day is be about £15000 a year. Meds shouldn't cost this much for anybody.
Gotta make shareholders profits.
@@bmstylee it costs billions of dollars to bring a drug to market - and that is those that actually make it all the way to approval. so many never make it that far, so they lose billions on all the research and development and time lost on those that never go to market. i do think that meds are overcharged, but there's a lot that goes on behind the scenes that nobody takes into account either.
I have no issues with making a profit. But what some of those companies charge for meds is outrageous. I guess you guys are happy knowing they make billions in profit while many people have to choose between having meds or putting food on the table.
@@bmstylee literally never said that. i said that med costs are ridiculous, especially for established meds outside of their patent (e.g. epipens). but yes. with the new wave of cell and gene therapies that are either tailored to the individual patient (sometimes even using their own blood) or are for conditions so rare, companies will never really recoup costs or if they do it will take decades. however, these orphan drugs are needed for those with rare disorders or they’ll just keep on ignoring them since there’s no profit to be made there. that’s why they need to profit elsewhere, to make those other treatments possible.
Someone tried quark rustling at CERN. They turned on the charm, and went up and down, but then things turned strange. The top and bottom of it was that some boson called Higgs positively negated their scheme when they were photoned making a quantum leap. They were dicharged and had to turn over a neutrino before they were let out of containment. The atmosphere was electric until the gravity of their situation hit them. The alternative would have been a strong spin for a weak in the collider.
Get a half life.
Imagine giving birth to a $2.1 mil dollar price tag😬
May I introduce you to college fees!
I'd like to watch a video entirely dedicated to Plutonium batteries (and other sorts of batteries that don't run on the chemical reaction between metal and acids).
This is what you want: ua-cam.com/video/TgxiE8hXfhs/v-deo.html
@@dansands8140 ... You're right! Thanks! 😀
4:02 that 87.7 year half life is for Pu-238, which is used in thermal power supplies (e.g. for long-haul space probes),
the kind used for nukes, Pu-239, has a half life of 24,100 years.
So when it goes off you mean that area is radioactive for basically the end of humanity?
11:43 As an author, the more I learn about anti-matter the more I want to learn. Anti-matter engines, anti-matter control chips, anti-matter mining.....the possibilities are endless
lets all appreciate how 1 man has built as big of a content farm as troom troom and 5 minute crafts
Mrs Richards: "I paid for a room with a view !"
Basil: (pointing to the lovely view) "That is Torquay, Madam ."
Mrs Richards: "It's not good enough!"
Basil: "May I ask what you were expecting to see out of a Torquay hotel bedroom window? Sydney Opera House, perhaps? the Hanging Gardens of Babylon? Herds of wildebeest sweeping majestically past?..."
Mrs Richards: "Don't be silly! I expect to be able to see the sea!"
Basil: "You can see the sea, it's over there between the land and the sky."
Mrs Richards: "I'm not satisfied. But I shall stay. But I expect a reduction."
Basil: "Why?! Because Krakatoa's not erupting at the moment ?"
One of my favourite comedic moments of all time 🥰
Slightly off topic though 🙃
@@thepartysjustbegun5557 I JUST SIGN MELBURY !
Actually gas station beef jerky is the most expensive item on the planet earth.
3:04 , well, I'll just say that this is somewhat of a misconception. You can actually get your hands on Plutonium quite easily. And it's legal, under a certain amount/weight. It's incredibly small in terms of amounts, but it's still enough to know for a fact that it's there. It's just that most sources available to normal people are from old smoke detectors called the RID-1 and the RID-6M, which are legal to own in the US. There may be a few others out there, but you can indeed get Plutonium out of them in the form of their ion sources. The 6M's are the most popular (and cheapest, at least in the states) and can even be bought on popular selling sites like ebay. I actually have like 8 of the 6M's and can easily detect them with my Geiger counter. Same can be said about Uranium. I have several ounces of the metal, as well as some granular chunks of Thorium metal. I can also get things like Actinium Sulfate, Technetium metal plated on a strip of foil like from the Periodic Videos YT video on it, etc. Another cool one is heavy water, or Deuterium Oxide. It has Deuterium as the Hydrogens in the water and it's the middle isotope between Hydrogen and Tritium. Though it's not radioactive. Again, this is all legal as long as you keep your samples under a certain amount of the materials. Now, anything weapons grade is illegal. But none of these samples are the isotopes that are illegal or even used for war.
Looking at the UK guidelines briefly it seems to be broadly similar to normal explosives. The material e.g high explosives doesn't seem to be the problem, its more that you are storing it safely, that its not a risk to others, and that the fire services know exactly where it is. But obviously they aren't going to give a licence to a terrorist, but a terrorist probably wouldn't be stupid enough to apply for one either!
@@engineeringvision9507 I don’t know iv heard about a LOT of dumb criminals/terrorists.
Americium
Was not expecting exit signs to be that expensive
They aren't, those signs sell for under $100...I checked.
@@Darth-Claw-Killflex not all do, the ones with tritium cost around $300-400. If they are used the glow is pretty dim and you can buy them for less than that
i knew Zolgensma would be on this list as the most expensive pharmaceutical in the world. my company handled the transportation of the drug while it was in development and also handles global distribution for all doses now that it is in commercial production. it's truly amazing the possibilities there are with these new gene therapies to replace faulty genes causing genetic disorders like SMA-1 and effectively curing them.
Does it travel in an armored car with a squad of mercenaries?
@@firstmkb haha no but then again it's not like it's something that has much in the way of street value and it's not like people would know what was in the vehicle like armored trucks carrying money or whatever would.
Tritium:
As a "Federally registered Nuclear radiation worker" In Canada, I have witnessed personally, Ontario Hydro workers, using tiny suction bottles picking up Tritium out of cracks in the concrete after a spill ...
Not surprised 😲
So why aren’t bananas exploding on my counter top?
The Voyager probes were exactly that, probes, not "shuttles".
the chance of a banana creating a explosion bigger than most nuclear bombs is low, but never zero
Tritium does not glow, it is a phosphor coating on the glass that glows when hit by alpha particles.
Plutonium is made by hitting Uranium 238 with neutrons, not deuterium!
tritium is a hard one because it’s so light so having one gram is a LOT
Apparently the money in my bank account is made of antimatter… as soon as it hits the account, it explodes and disappears. 😂💸
Emotionally burdening and ethically questionable is the best description for you i have ever heard.
The last one explains why my bananas keep exploding.
funny thing about the plutonium in BTTF is that it's shown as a red liquid (not green at least i suppose...) rather than a grey solid .
Didn't realise emergency signs used radioactive material though, but makes sense when you think about it
I’m convinced that the world doesn’t harness responsible nuclear power because there is no money in it.
What exactly do you mean by there not being any money in it? For what reason?
If because the power would be too cheap, then that's the same kind of nonsense as claims that pharma doesn't want to cure anything because that would eliminate the market.
Apparently the sentiment is more apathy, dealing with activists / protests and realising the misinformation about radiation is embedded in many populations means they've struggled to get public, and therefore government support. Def in Australia anyway, which is a shame.
I've got a tritium keyring, the exact one as shown at 2:12 it's cool
Hey this ain’t Michael from v sauce
I love it that you called out DeBeers! 🤣
30000 bucks a gram? So, why aren't the Japanese extracting the stuff from the cooling water in Fukushima Daiichi? Oh right, it's so little that it's not worth it, and won't do any environmental damage if diluted further.
Not surprised a drug is on the list. My $1700 insulin doesn’t sound to bad compared to this one.
Zolgensma cures a very rare disease so it makes sense to be expensive with the low number of dossis sold and the required research.
Insulin is quite cheap to produce, the costs of its research and development are already paid in full many times over. It's the combination of an inefficient healthcare system and crooked morals by big pharma what makes it so expensive.
So yeah, not really the same.
10:59 That's why Doc Brown put's bananas in his DeLorien!
Most of my firearms have tritium sights, lol.
There is something satisfying about that green glow sitting on the nightstand.
I just got a pacemaker. It's crazy the technology in such a small device.
Fyi the device check where they use the pacemaker to increase your pulse is wild. It's just a few secs but weird.
@@andiward7068 I have had mine for 14 years. But just got a new one a month ago that has like a wifi thing that transmits all the info. But yeah I would have to go every 6 months and the rep would put this halo thing over the pacemaker and press buttons and play God. Lol yeah its weird. I got the pacemaker at 27 years old. Crazy times
@@mattpaul5441 Mine is pm/defib. I've got the wifi box too but I need to connect it. I prefer going in person because they can tell me what was going on but w/the box I'll only know if it's something major. It's a mental thing, I'm working on it. I was 38 but still youngest recipient at that hsp. Yay us! Early adopters unite.
@@andiward7068 I hear ya. Sorry you had to go threw that. The defib. Is no joke.
@@mattpaul5441luckily it's never gone off. My function was nearly normal in hsp before the implant and it was debatable if I really needed it. Drs decided to err on the side of "jic". (Idiopathic CHF.)
3:42 No wonder Donatello Hamato is so hell-bent on acquiring military-grade uranium lol
would love to see a video on the viability of these radioactive fuel sources in cars
Viability: None whatsoever.
He did a video about nuclear powered vehicles on this channel titled "Nuclear Powered Vehicles: Cheap, Sustainable, and Potentially Deadly"
you can actually harvest antimatter in the same way you produce xrays. lightning for instance creates antimatter - we know this from satellite observations. so the price per gram is actually very far from optimal. i would imagine antimatter could be scarry cheap in the near future.
Tritium is also used in night sights for handguns.
Zolgensma is also available for free on the NHS in the UK
Thanks for your research ❤️
I actually heard about this drug. The company that makes it says that insurance nearly always covers it. It pretty much is *the* definition of "medically necessary". The one issue is that treatment does sometimes require more than 1 dose.
Insurance company bureaucrat: "And what happens if the kid doesn't get this?"
Doctor: "The kid dies."
Insurance company bureaucrat: "And how likely is that?"
Doctor: "Just about 100%."
Bureaucrat: "Ok."
Popcorn in a theater has a 1200% markup. Ouch.
Simon really dropped the ball. No mention of black printer ink!?!
So Zolgensma is just extortion, because it could easily be made cheaper for the benefit of humanity.
4:30, *Insert Energizer Bunny here*
I thought it best to point out emergency exit signs are required by code (building and fire) to work for "at least 8hrs", and they're required to be tested periodically. (when moving into new office space, we can't get a certificate of occupancy without them being power-out tested for 8 hours.) Thus, those LED based signs will work for hours; probably many more hours than they ever need to. (when the power is out, I usually leave within 8 hours.)
And who wants to bet that the Zologensama costs next to nothing to make?
Probably doesn't cost much to make; that's irrelevant. How much was spent on developing it - that's where the cost is.
It's not like a regular Joe stumbled across it by accident. Scientists aren't cheap!
@@dennishilmas3423 yep, and of course that's the problem with such medicines. Firstly this is an incredibly rare disease, a couple of thousand patients a year globally. The drug would have cost hundreds of millions to develop. Unlike, say, a flu vaccine, which will be sold in hundreds of millions of doses, this drug will be sold in its tens of doses.
Now I am not one for forgiving drugs companies, some of their practices are disgusting, but the reality is that such drugs need money to develop them and in order to raise the money a return on the investment is needed. It would help the drug company 's causes if they were transparent on their profit margins.
The answer to funding these doses is in the funding of treatment. Models to raise the funds to treat sick children are where the focus needs to be and Novartis say, subsidising the cost of such funded doses rather than a 'lottery 'would be more egalitarian and also fairer.
@@dennishilmas3423 So I assume that when the costs have been covered, the price will plummet drastically?
So, you are thirsting and lost in the desert?
Pay me 2 millions for half a liter of luke warm water.
Ha, I found the new most expensive material!
8:40 I wouldn't say any parent, you have way too much faith in humanity. It's far cheaper to just let it die and start over and try again, a pregnancy and raising a kid to a year old while waiting for it to die only costs about 1% as much, about $21k.
Wouldn't you get charged with first-degree murder though?
@@Anonymous-df8it Only if the cops find out about it. Home birth + mother stays home the whole 9 months = no one will even be aware anyone was killed or missing. It happens more often than you think. And that's for outright murder/manslaughter. Letting nature do it because you can't afford to prevent it = nope, not the parent's' fault so no charges if nature does it. In the US 3 people a minute die 24/7 due to not being able to afford health care or some overpriced treatment.
Another great video from the hardest working man on the internet!!
I don't think mineral have species, though that was only animals??
The Russians and I should think a lot of large companies use those plutonium generators from voyager for radio controlled operations in areas where power lines couldnt get to. This is a pretty similar use as the voyagers. Uses included dam gates operation and signal repeaters or communications towers to power radio equipment and linear amplifiers for amplifying radio signals over very large spaces. As for antimatter it is used in medicine all the time. They use it for P.E.T. scans hence the P for positron the antimatter equivalent of an electron. Really makes me mad when people moan about CERN creating antimatter as it is done a lot in nuclear medicine . It is very very hard though to produce whole atoms of antimatter and CERN are doing that but the parts of an atomic structure frequently decay and when this happens we get anti matter particles that last less than a nanosecond being emitted as part of atomic decay. They call antimatter in a sizeable amount anti matter rice . They have not made that much yet but thats what they call it.
My guy legit lookin like Bargain bin Michael Stevens
The batteries last 90 min on exist signs. And should be replaced about every two years. You can test them with a button by the little green or red led on the side or bottom.
The "Plutonium battery" is called a SNAP drive..