Which combination of drugs will you choose for treatment of Parkinson’s disease?

Which combination of drugs will you choose for the treatment of Parkinson’s disease?
Options are:
A. Amantadine, carbidopa, and entacapone.
B. Levodopa, carbidopa, and entacapone.
C. Pramipexole, carbidopa, and entacapone.
D. Ropinirole, selegiline, and entacapone.
E. Ropinirole, carbidopa, and selegiline.
The correct answer is
Levodopa, carbidopa, and entacapone.
Because Levodopa will increase the dopamine levels in the brain. But to avoid the metabolism of levodopa in the body by Dopa decarboxylase enzyme, carbidopa will be needed. And to avoid metabolism by
catechol-Omethyltransferase enzyme, Entacapone will be needed.
Therefore, with the help of carbidopa and entacapone, more levodopa will enter the brain.
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