I took l-glutamine for over a year bc I thought I had leaky gut. When my digestion got better I stopped it. It's been about a year since I took it, but I'm having a lot of the digestion problems again; mainly heartburn & bloating. I also seem to be unable to stop eating wrong foods! I've been having brain fog, constant pain and an inability to get off my couch or make decisions. I'm about to start l-glutamine again as I think I MUST need more than I get. I like most of the foods you listed, I just don't eat much bc of my digestion. I never realized it could have such an impact on thinking, so want to thank you for this info. I've listened to you for YEARS, but rarely see you anymore on my feed. I'll have to remember: NOOTROPICS EXPERT ❣✌
I love you David, you're the most Decent person in this Nootropics community and you're the only person I rely on, on this Topic you helped me a lot. You're like my doctor lol, keep up the good work never give up!
L-glutamine: so many good things for the brain and body. Max upper dosage is 50-60 grams per day. We just started on 3 to 4 scoops per day. Taking for weight issues, but now discovering so many good things from this humble amino acid.
If you are using it to boost athletic performance and speed recovery, both forms of L-glutamine are best taken right before or after a workout. Using it with small meals before or after your workout session can help support your metabolism and weight loss goals. And will assist in muscle building, recovery and maintenance. Other than that you can use it anytime and get the benefits described in this video..
Hi David - the side effects you listed: sweating, flatulence, skin rash, vomiting etc unclear what would causes those? Is it too much L glutamine, imbalance of Glutamate and GABA? Too little Glutamate? Thanks again! Love your videos
Bob, those side effects are rare and most do not experience them. IF someone experiences any of those side effects it could be caused by various things including those you mention. If that happens try cutting back the dose or avoid it altogether.
Can L-Glutamine be taken when someone is on several medications? I’ve been trying to do some research on it for my dad, so far I can only find some of the side affects or when not to take it, but none of those include medication someone might be on
Hello! I suffer from idiopathic chronic constipation , not related to eating habits, lack of hydration or exercise. After seeing 2 gastroenterologist and one colorectal surgeon with very little results. I decided to see a functional doctor. One of the supplements she recommended to take is l glutamine powder. I always do research on what I take and I read that l glutamine can cause constipation. In fact that is how I found your video. I see that you say is very rare but well I am now hesitant to take it. What are your thoughts about someone already constipated taking this? Thanks
The only way to find out if this is true for you is to try the supplement. What's the worst that can happen? You'll be constipated? You are already there so that's not much of a change. But imagine if it solved your problem? Don't let your fear stop you from doing a little experimenting because it feels really, really good to feel better. :-)
Now i know why glutamine not suits for everyone. If anybody have sibo glutamine makes you depressed and anxiety because bad bacteria is not makes glutamine or any other supplements working. So, remove sibo first and try any other supplements what you need.
Will l glutamine cause me to have seizures? I want to supplement for gut health, but I'm scared. I currently take lamotrigine 100mg for epilepsy but in my opinion, it doesn't work and hasn't worked ever.. I have seizures around the menstrual cycle and my Dr says he's never heard of that so he don't believe me 🤦🏾♀️😢 Also, I'm wondering if l carnitine causes seizures too because everytime I've used it, I've had a seizure?? - gym training - I'm trying to better my health and fitness. Should I be avoiding l carnitine?
Debbie, if you are prone to seizures you should avoid using L-Glutamine and carnitine including Acetyl L-Carnitine (ALCAR). Because using either of them could result in you having seizures. If you want to heal a leaky gut check out some of the supplements I mention in this video: ua-cam.com/video/r38OSqyPvyM/v-deo.html. Because what applies for a leaky brain also applies for a leaky gut.
If that isn't working and has never worked it means you don't have a problem with GABA. It is caused by a dysfunction of something else. And the only way to figure it out is try other precursors. See my newest video on anxiety for how to do it. But whatever you do don't use anything that increases GABA while you are on that drug. Including not using L-Glutamine.
can I take this if I am on klonopin and still feeling anxious. I am taking a probiotic that has lactobacillus rhamnosus and L-glutamine.......but if the L-glutamine converts glutamate then will this mess up my downregulated Gaba from the klonopin....my doctor is clueless about this and knows nothing about probiotic. Do you know which probiotic helps anxiety? Thank youl
Irwan, there are some videos that suggest nootropic stacks for various issues. I suggest scrolling through the videos for the ones available for things like ADHD, PTSD, TBI, and others.
So since this is not recommended when you have any form of cancer since it encourages tumour growth this is very worrying as well as confusing. Cancers are apparently occurring in our bodies all the time but normally our metabolism deals with it. Would taking L glutamine then encourage these latent tumours to develop? Also I read somewhere that when you are receiving chemo taking L glutamine can alleviate some of the awful side effects from that treatment. What you are saying suggests that you shouldn't be taking it at all when you have cancer. All this conflicting information is extremely confusing. What would you say to this ?
Christine, it's much more complicated than that. If you want to take a deep dive into the study of glutamine metabolism and cancer cells try getting through this: www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5746034/ The bottom line is supplementing with Glutamine does NOT cause cancer. if it did, all the athletes who use L-Glutamine to boost Human Growth Hormone would be all dying of cancer. And that is not the case.
Hello David i’ve been getting alot of brain zaps lately do you think that means my gaba and glutamate are off ? What would you recommend for it ? Other then good sleep which im lacking as of late :/
Jonathan, you are likely deficient in magnesium. Try 400 mg about 60 minutes before bed of this supplement: pulse.ly/n7m3r65d30. (Amazon) and see if that helps. I may take 4 - 5 days to get your levels up before you'll know.
Hi Dr! If I currently have an endometrioma with endometriosis damaging my gut, should I avoid taking L-glutamine? I thought I could take it yo heal my gut but since you’ve mentioned tumors, now I am not so sure
Some recent research has shown that L-glutamine can stimulate tumor growth. So if you are dealing with any form of cancer you should not use L-glutamine.
I take anti-depressant and have psoriasis and everyone suggesting to take l-glutamine to heal leaky gut to clear my psoriasis. But I am concerns, as you said l-glutamine is converted to glutamate which is harmful in high quality. Please help.
Yash, using L-Glutamine and/or GABA will help keep glutamate in check. And in balance. It's if you are deficient in either glutamine or GABA is when glutamate can go toxic on you.
Some recent research has shown that L-glutamine can stimulate tumor growth. So if you are dealing with any form of cancer you should not use L-glutamine. But no mention of fibroids. I suggest doing a little more research on that before you try it.
@@jjm2948 Jason, no change. It's just I can't keep up with managing comments on this channel for all the videos while running the rest of Nootropics Expert.
Irena, this article is on how to heal a leaky brain but it applies to a leaky gut as well: nootropicsexpert.com/how-to-heal-a-leaky-blood-brain-barrier/. I think I may have done a video on this as well.
I had a neurotransmitter test results come back with high glutamate levels Glutamine and the 5 main neurotransmitter levels were all normal Is l glutamate something I should consider does it normalize glutamate levels? Thanks
Ken, you can normalize the glutamine/glutamate/GABA cycle by supplementing with L-Glutamine. Too much glutamate is not a good thing because excess glutamate is toxic. You can also add a PharmaGABA supplement if L-Glutamine isn't enough.
Vanessa, if you have a severe mental disorder which also includes schizophrenia, mania or frequently have seizures you may want to avoid L-glutamine. Because it could make matters worse.
Hi David, most informative, may I ask ? I’m taking L . Glutamine ( 3-4 gms daily ) for reflux and have found it to be “ amazing “ but as I also have MGUS in your opinion , is it safe for me to continue ? Many thanks ( UK )
I don't think you missed it in the video because I didn't include it. But animal studies show that Vitamin B12 increases GABA which then decreases glutamate (pubmed.ncbi.nlm.nih.gov/9249572/). The cycle glutamine/glutamate/GABA must be in balance. If glutamate or glutamine or GABA gets elevated it messes with this balance and bad things can happen. The easiest way to keep this in balance if using L-Glutamine long-term is to also supplement with GABA. If that alone does not do it then add Vitamin B12 or a high quality B-Complex.
I just got L-Glutamine today and I havent felt this calm and grounded in my body for almost 20 years - Wow!
Samuel, it goes on to produce GABA so it sounds like you were GABA deficient.
I took l-glutamine for over a year bc I thought I had leaky gut. When my digestion got better I stopped it. It's been about a year since I took it, but I'm having a lot of the digestion problems again; mainly heartburn & bloating. I also seem to be unable to stop eating wrong foods!
I've been having brain fog, constant pain and an inability to get off my couch or make decisions.
I'm about to start l-glutamine again as I think I MUST need more than I get. I like most of the foods you listed, I just don't eat much bc of my digestion.
I never realized it could have such an impact on thinking, so want to thank you for this info. I've listened to you for YEARS, but rarely see you anymore on my feed.
I'll have to remember:
NOOTROPICS EXPERT ❣✌
I love you David, you're the most Decent person in this Nootropics community and you're the only person I rely on, on this Topic you helped me a lot. You're like my doctor lol, keep up the good work never give up!
I appreciate it and thank you.
L-glutamine: so many good things for the brain and body. Max upper dosage is 50-60 grams per day. We just started on 3 to 4 scoops per day. Taking for weight issues, but now discovering so many good things from this humble amino acid.
I love the benefits sections, not just sticking with the brain benefits
Thank you for an informative video. Much appreciate your advice
One of the most worthwhile channels on this medium as opposed to The Beast for example
Thank you. Much appreciated. Not sure who the Beast is but tell him or her I send my regards.
Thank you for all this info! What great detail!
Glad you enjoyed it Heidi!
Your channel is the bomb !
Thank you for taking time and giving us this great information.
My pleasure Mohammed. Thank you!
Expert indeed
Great content starting using it,thanks for sharing!!!
Thank you Bhupen.
So what do you notice
FANTASTIC content! 💉
Thank you Darren.
When is the better time to take l glutamine? Before bed, on empty stomach, on morning, during a meal?
If you are using it to boost athletic performance and speed recovery, both forms of L-glutamine are best taken right before or after a workout. Using it with small meals before or after your workout session can help support your metabolism and weight loss goals. And will assist in muscle building, recovery and maintenance.
Other than that you can use it anytime and get the benefits described in this video..
@@NootropicsExpert thank you for the answer and advice.
Thanks again. I read Seyfried's book and am worried about feeding cancer cells if I try to avoid leaky gut. #SMH
Thanx from Egypt 🇪🇬👍
Welcome!
Hi David - the side effects you listed: sweating, flatulence, skin rash, vomiting etc unclear what would causes those? Is it too much L glutamine, imbalance of Glutamate and GABA? Too little Glutamate? Thanks again! Love your videos
Bob, those side effects are rare and most do not experience them. IF someone experiences any of those side effects it could be caused by various things including those you mention. If that happens try cutting back the dose or avoid it altogether.
Thanks for your efforts , do you think l glutamine can help with anhedonia , i have some benign thyroid nodules there is any risk in this case ?
Honestly not sure. It is said to promote tumor growth. But if they're "benign" ...
Can L-Glutamine be taken when someone is on several medications? I’ve been trying to do some research on it for my dad, so far I can only find some of the side affects or when not to take it, but none of those include medication someone might be on
Claudia, I"m not aware of any med contraindications.
Excellent
Thanks
I am suffering stomach and intestinal problems after stopping gabapentin. Will L-glutamine supplement help or hurt me.??
William, it should help rather than hurt you.
Hello! I suffer from idiopathic chronic constipation , not related to eating habits, lack of hydration or exercise. After seeing 2 gastroenterologist and one colorectal surgeon with very little results. I decided to see a functional doctor. One of the supplements she recommended to take is l glutamine powder. I always do research on what I take and I read that l glutamine can cause constipation. In fact that is how I found your video. I see that you say is very rare but well I am now hesitant to take it.
What are your thoughts about someone already constipated taking this? Thanks
The only way to find out if this is true for you is to try the supplement. What's the worst that can happen? You'll be constipated? You are already there so that's not much of a change. But imagine if it solved your problem? Don't let your fear stop you from doing a little experimenting because it feels really, really good to feel better. :-)
Now i know why glutamine not suits for everyone. If anybody have sibo glutamine makes you depressed and anxiety because bad bacteria is not makes glutamine or any other supplements working. So, remove sibo first and try any other supplements what you need.
Will l glutamine cause me to have seizures? I want to supplement for gut health, but I'm scared. I currently take lamotrigine 100mg for epilepsy but in my opinion, it doesn't work and hasn't worked ever.. I have seizures around the menstrual cycle and my Dr says he's never heard of that so he don't believe me 🤦🏾♀️😢
Also, I'm wondering if l carnitine causes seizures too because everytime I've used it, I've had a seizure?? - gym training - I'm trying to better my health and fitness.
Should I be avoiding l carnitine?
Debbie, if you are prone to seizures you should avoid using L-Glutamine and carnitine including Acetyl L-Carnitine (ALCAR). Because using either of them could result in you having seizures.
If you want to heal a leaky gut check out some of the supplements I mention in this video: ua-cam.com/video/r38OSqyPvyM/v-deo.html. Because what applies for a leaky brain also applies for a leaky gut.
What can I take to calm down anxiety if I am taking klonopin 1 mg and it is not helping.....
If that isn't working and has never worked it means you don't have a problem with GABA. It is caused by a dysfunction of something else. And the only way to figure it out is try other precursors. See my newest video on anxiety for how to do it.
But whatever you do don't use anything that increases GABA while you are on that drug. Including not using L-Glutamine.
can I take this if I am on klonopin and still feeling anxious. I am taking a probiotic that has lactobacillus rhamnosus and L-glutamine.......but if the L-glutamine converts glutamate then will this mess up my downregulated Gaba from the klonopin....my doctor is clueless about this and knows nothing about probiotic. Do you know which probiotic helps anxiety? Thank youl
Lactobacillus (L.) rhamnosus (www.ncbi.nlm.nih.gov/pmc/articles/PMC6010276/)
Can i take glutamine for increasing gaba and Deep sleep? Also wanna try taurine for gaba production.
Try l-Glutamine and PharmaGABA because each or both will increase GABA in your system.
@@NootropicsExpert pharmagaba is not available in my country. Any alternate supplement?
Any side effects on kidneys? Thanks
Not that I am aware of.
are therevideos where you discuss about the best nootropic combinations?
Irwan, there are some videos that suggest nootropic stacks for various issues. I suggest scrolling through the videos for the ones available for things like ADHD, PTSD, TBI, and others.
So since this is not recommended when you have any form of cancer since it encourages tumour growth this is very worrying as well as confusing. Cancers are apparently occurring in our bodies all the time but normally our metabolism deals with it. Would taking L glutamine then encourage these latent tumours to develop? Also I read somewhere that when you are receiving chemo taking L glutamine can alleviate some of the awful side effects from that treatment. What you are saying suggests that you shouldn't be taking it at all when you have cancer. All this conflicting information is extremely confusing. What would you say to this ?
Christine, it's much more complicated than that. If you want to take a deep dive into the study of glutamine metabolism and cancer cells try getting through this: www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5746034/
The bottom line is supplementing with Glutamine does NOT cause cancer. if it did, all the athletes who use L-Glutamine to boost Human Growth Hormone would be all dying of cancer. And that is not the case.
Hello David i’ve been getting alot of brain zaps lately do you think that means my gaba and glutamate are off ? What would you recommend for it ? Other then good sleep which im lacking as of late :/
Jonathan, you are likely deficient in magnesium. Try 400 mg about 60 minutes before bed of this supplement: pulse.ly/n7m3r65d30. (Amazon) and see if that helps. I may take 4 - 5 days to get your levels up before you'll know.
Hi Dr! If I currently have an endometrioma with endometriosis damaging my gut, should I avoid taking L-glutamine? I thought I could take it yo heal my gut but since you’ve mentioned tumors, now I am not so sure
Some recent research has shown that L-glutamine can stimulate tumor growth. So if you are dealing with any form of cancer you should not use L-glutamine.
I had a brain tumor removed 5 years ago. Should I not take L-glutamine?
Yes, it's best to avoid L-Glutamine just to be safe.
I take anti-depressant and have psoriasis and everyone suggesting to take l-glutamine to heal leaky gut to clear my psoriasis. But I am concerns, as you said l-glutamine is converted to glutamate which is harmful in high quality. Please help.
Yash, using L-Glutamine and/or GABA will help keep glutamate in check. And in balance. It's if you are deficient in either glutamine or GABA is when glutamate can go toxic on you.
Can you take L-Glutamine if you have uterine fibroids? Those tumors aren’t cancerous but they are tumors. Thank you
Some recent research has shown that L-glutamine can stimulate tumor growth. So if you are dealing with any form of cancer you should not use L-glutamine. But no mention of fibroids. I suggest doing a little more research on that before you try it.
@@NootropicsExpert Thank you so much for answering! I will research further. Thank you thank you
@@jjm2948 Jason, no change. It's just I can't keep up with managing comments on this channel for all the videos while running the rest of Nootropics Expert.
Can i take glutamine,i had 3 years ago 2 aneurizm surgeries,..i have a leaky gut,.. can that help me?
Irena, this article is on how to heal a leaky brain but it applies to a leaky gut as well: nootropicsexpert.com/how-to-heal-a-leaky-blood-brain-barrier/. I think I may have done a video on this as well.
Can you use l glutamine for the gaba and serotonin it produces?
L-Glutamine helps make glutamate, GABA and Human Growth Hormone. it does not directly affect serotonin.
Thank you
How do I use Glutamine for sleep? I'm concerned that I'll be one of those sub-types that have a bad reaction.
Best to try the lowest recommended dose at first to see how you respond. That's the only way to find out if you are "one of those sub-types".
How about L glutamine and uric acid?
What about it?
I had a neurotransmitter test results come back with high glutamate levels
Glutamine and the 5 main neurotransmitter levels were all normal
Is l glutamate something I should consider does it normalize glutamate levels?
Thanks
Ken, you can normalize the glutamine/glutamate/GABA cycle by supplementing with L-Glutamine. Too much glutamate is not a good thing because excess glutamate is toxic.
You can also add a PharmaGABA supplement if L-Glutamine isn't enough.
I'm confused. Are you saying a schizophrenic person should not take L-Glutamine supplement?
Vanessa, if you have a severe mental disorder which also includes schizophrenia, mania or frequently have seizures you may want to avoid L-glutamine. Because it could make matters worse.
@@NootropicsExpert thank you!
Is L Glutamine safe long term?
Rhonda, L-Glutamine is safe to use long-term as long as you stay within recommended dosages.
@@NootropicsExpert Thank you. I am taking 5G max per day. BIG improvements after just 5 days! Thank you for your response :)
Hi David, most informative, may I ask ? I’m taking L . Glutamine ( 3-4 gms daily ) for reflux and have found it to be “ amazing “ but as I also have MGUS in your opinion , is it safe for me to continue ? Many thanks ( UK )
I cannot find any information on Glutamine if you are dealing with MGUS. Best to ask your doctor about this one.
@@NootropicsExpert Many thanks for spending the time to get back to me I will do as you say
@@NootropicsExpert May I just add it is L glutamine safe to take every day for ordinary individuals with no health issues Thanks
Is it true to take B12 if you’re taking glutamine long term to keep glutamate in check? Sorry if I missed it in the video
I don't think you missed it in the video because I didn't include it. But animal studies show that Vitamin B12 increases GABA which then decreases glutamate (pubmed.ncbi.nlm.nih.gov/9249572/).
The cycle glutamine/glutamate/GABA must be in balance. If glutamate or glutamine or GABA gets elevated it messes with this balance and bad things can happen.
The easiest way to keep this in balance if using L-Glutamine long-term is to also supplement with GABA. If that alone does not do it then add Vitamin B12 or a high quality B-Complex.
Is Alpha Ketoglutarate the same thing as L-Glutamine?
Mark, negative. α-Ketoglutarate is transaminated along with glutamine to form the excitatory glutamate.
Third
Second
First
Fourth
Sixth
Fifth.
Fifth