Biotechnology: Crash Course History of Science #40
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- Опубліковано 7 вер 2024
- The history of discovering what DNA is, what it looks like, and how it works is... complicated. But, in this episode of History of Science, Hank Green does his best to lay out the basics so we can understand the beginnings of Biotechnology.
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“Erwin Schrödinger, yeah, the cat guy” You just offended every theoretical physicist ever
Haha :D
- Nick J.
To be fair, if you type Schrödinger into google the first auto-complete is cat. It is clearly what he is famous for :)
It's cruelly ironic that Franklin died because of an error in replicating the structure of her DNA.
Patrick Reding yeah, her own X-rays killed her. Sad.
@Patrick Reding Get. Out.
this channel is useful and i try to make my channel like this
Crashcourse is the gift that keeps on giving
+
Yes, Nice pic btw
streamouss prod
Thanks man
really i found it very interesting and i use its information in my channel
CRINGE
Thanks for another very interesting overview and for giving Franklin more than a passing reference.
It makes you wonder how many scientific discoveries had women who were central to the progress, but got written out of history...
Eyyy, random DCA fan represent!
Mr Shambleface ikr
In our book there are three separate chapters of these topics that you included in freaking 12 minute video.
Freaking admirable
You should talk about the revolutionary techniques that arose in Biotechnology and Biochemistry in the last 70 years, like PCR and the like
"Watson was a psuedo-scientist and stupid" this was the phrase of my teacher who said it at the starting of the lecture when she was teaching genetics. 😂😂
It's almost 4 am. I'm in a lab, imaging gentically modified worms (C. briggsae) ie using biotech.....and watching this.
I used to work with C. elegans! Hello from one nematode person to another.
@@chillsahoy2640 I work on that one too! Yay nematode friends!
Honestly, its so refreshing to hear scientific review and information while simultaneously calling out that community for its many ills. Thank you so much for this.
Hi Crash Course Team! I'm wondering if you guys could do a series on cities? As in town planning. What makes good cities and look at both historical and present theories and cities? Would be amazing!!
Yes!!! I studied this and we did a lot of sequencing! Tough class but very interesting
Crash course history of science is the most interesting crash course of
all crash courses
With CRISPR and such biotechnology is going through another revolution imo!
Your explanation is so good it enable us to learn easily.. Thank for your awesome video sir..😀
You'd think that with time we would understand more of the world, but it usually results in "we now know that it's more complex than that.."
Can you please make a video on HUMAN GENOME PROJECT???😍😍
Shrodin-JER?! With the trend of the unusual pronunciation of names in this series, I feel like you are trolling us :D
He managed the ö very well tho, German isn't easy (Swiss German even less).
@@fionafiona1146
The english language has the "ö" sound. Maybe not on its own, but still. I would be more impressed if the "r" wouldn't be the half gargled, half swallowed "r" ;) .
The first half of the name was quite good, while the second had some problems.
I LOVE THIS SERIES! It brings together two of my favorite subjects! And the discussions are insightful and informative and funny. Truly brilliant job, everyone!
The Secret of Life by Howard Markel gives a great account of the work of Watson, Crick, Wilkins, and Franklin.
Love this channel! I’m inspired to make more videos to help high schoolers !!! 😝😝
Hope your channel goes well
I'm Up Next thank you!!
It is a revelation reading about Schroedinger to be delving his way into biology by simply asking the question: "How does this gene physically encode the information that defines life?" Highly analytical question from a very analytical mind that threw into Physics his famous Schrodinger Equation! Another revelation was the information regarding a woman who was around during the time that the DNA structure was discovered. Years ago, as I read the narration regarding how the DNA Structure was discovered, it left me with an impression that personal conflict can exist between colleagues. It amused me, especially as I looked around and saw little disagreements here and there between famous people in my own sphere. Those observations were simply erased as I look back and digested DNA's discovery and concluded: "The observations I have regarding people's conflict is just small compared to the event on how DNA was discovered!" I was amused then, but not amused now knowing that the notes from Franklin was being used by Watson and Crick without her knowledge! There was a mention of Bragg in that book but I didn't remember of any Franklin. The term you used "BRASH" was not enough... Another revelation regarding a "mole" within a scientific endeavor: As you have said, Wilkins was passing Franklin's notes to Watson and Crick. Is there any punishment for a "Science Spy"? Another revelation which I am going to give in a question form: Is there a possibility to create HUMAN LIFE by means of Biotechnology?
Biotechnology is a technology that involves the use of living organisms. Biotechnology is mainly used in agriculture, food science, and medicine. In biotechnology, living organisms are used to make useful chemicals and products or to perform an industrial task.
So, the used of biotechnology is through DNA sequencing, genomic information is used to create maps of the DNA of different organisms using the biotechnology. Biotechnology, or the use of biological agents for technological progression, has applications in medicine, agriculture, and in industry, which include processes such as fermentation and the production of biofuels. Therefore, this is nowadays are still being used specifically by determining the human genom and phenotype.
Studying life is not complete without studying the biotechnology. And we know that DNA is relates to genes which is related to life. Studying DNA is more like hard to understand on how it connects to each other and how does the genes are being inherited to another generation, how much more when they had discovered DNA. And by this episode it briefly explains how they had studied and discovered the DNA. Biotechnology has a big impact in the history of science because it is related in studying life and many more.
I do not have actually interest about this things like genes, biotechnology and etc. But since it discusses what and how life is I should make some time to understand this thing. Everything is interconnected, by watching this video i learn many things about life, like how this DNAs, genes were the primary twin of life. It drive us in understanding the life. How this thing interconnected to define Life, this biotechnology help us to understand even more the LIFE.
Biotechnology is nearly as old as humanity itself. The food you eat and the pets you love? You can thank our distant ancestors for kickstarting the agricultural revolution, using artificial selection for crops, livestock, and other domesticated animals. When Edward Jenner invented vaccines and when Alexander Fleming discovered antibiotics, they were harnessing the power of biotechnology. And, of course, modern civilization would hardly be imaginable without the fermentation processes that gave us beer, wine, and cheese!
Modern biotechnology provides breakthrough products and technologies to combat debilitating and rare diseases, reduce our environmental footprint, feed the hungry, use less and cleaner energy, and have safer, cleaner and more efficient industrial manufacturing processes.
Recent advances in biotechnology are helping us prepare for and meet society’s most pressing challenges. Currently, there are more than 250 biotechnology health care products and vaccines available to patients, many for previously untreatable diseases. More than 13.3 million farmers around the world use agricultural biotechnology to increase yields, prevent damage from insects and pests and reduce farming's impact on the environment. And more than 50 biorefineries are being built across North America to test and refine technologies to produce biofuels and chemicals from renewable biomass, which can help reduce greenhouse gas emissions.
In my 8th grade, we had a subject called Biotech. And i always look forward to this lecture since i like science so much and that our teacher is really good at explaining things. We always had fun before with learning about DNA. And i admired of couse Watson and Crick for their discovery of DNA, but i was disappointed upon knowing the real story with them copying Franklin's work. This just shows how greedy humans are just for fame and recognition. It's a sad fact in this world. Regardless, biotechnology advanced with the discovery of dna making people think of endless possibilities to do with it. It's exciting really.
Make a crash course on Mathematics man that's only leftover pleaseeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee
8:57 not entirely true. moleculat phylogenetics has truly been a revolution in the study of evolution. however, physical features are still used to study evolution. in fact, it is the only way to study evolution in fossiles, like dinosaurs. dna in evolution can only be used in non-extinct organisms. and physical features are as much reliable as dna, since molecular phylogenetics have many issues and problems as well. in fact, you can get many different results depending on the dna sequence you use, or the algorithm to build the phylogentic tree, or to build the multiple sequence alignment. same basic problems with physical features.
Crash Course General Western Music Theory (with Jacob Collier? Adam Neely?)
Crash Course "Indian Music Theory" (??) (a person who knows their stuff, not a lot of resources out there for english-speakers)
Crash Course Music Theories (with Herbie Hancock? Rick Beato)
Crash Course Written (worldwide, like really) Music History (with Adam Neely? David Hudry?)
Crash Course Popular (worldwide, like really) Music History (with Rick Beato?? Hank Green?)
this could happen. in the next ten years. it's doable. keep up the great work.
This is a great series and I hope to see more like it.
I have a test on biotech tomorrow. Thank you CrashCourse! :)))
I thought most of that sounded familiar. Didn't almost all of the patent-able biotech talk go practically verbatim into the forward of the Novel Jurassic Park. Was getting Velociraptor flashbacks.
Plz do a crashcorse on pharmacy
The matching plaids on Hank's shirt make me so happy
I feel so sad for Franklin
..
More about biotechnology please!!!!!!
Franklin is wearing a left-hand foam #1 glove on her right hand. Thought Bubble are you drunk?
I certainly am looking forward to when Biotechnology finds a cure or vaccine for HIV.
The "cure" is replacing white blood cells by radiation therapy and bow marrow transplant (from someone immune to the strand of HIV in the patient)... That too will keep you on live long imuno suppression, with higher side effects and death rates
But it isn't as easy as removing the HIV strand?
Fiona Fiina is describing what is known as the "Berlin Treatment", I believe. As for removing the HIV itself, the Draco treatment was purported to cause cells with double stranded RNA (which i believe HIV is) within them to self destruct, which could also destroy the immune system of the patient if the infection progresses.
@@TentacleseRex
Since a second case has been without sudden death for 2 years now, we might need a new name tho, especially if the Berlin patient eventually dies.
@@orionanderson6719
Well, have you heard of that crazy chinese doctor, who genetically modified human zygotes? It was all over the news a few months ago.
I'm a chemist, not a biochemist, but here's the gist of it:
HIV is a virus and viruses target specific cells as their host. In the case of HIV it's the white blood cells (which are an integral part of your immune system, which is why HIV is so bad).
How the virus can detect which cell is a host cell is rather simple: Cells have proteins on the outside of their cell-membranes. In biochem, those proteins are called 'tags'. Each type of cell has a unique tag, you can think of them as little name tags if you'd like.
The virus is blind, but has a protein on it's own, which fits to a specific tag of it's target cell - like a lock and a key.
Now back to the story of the crazy chinese doctor: As Hank said in the video, the central dogma in biochem is "DNA to RNA to Protein". To put it more simply: Each section on your DNA is like a blueprint for proteins. Now, remember: That tag on your white blood cells is a protein too.
The chinese doctor modified the DNA of two human zygotes in a way, that the DNA section that codes for that protein tag is not readable. Therefore there's no tag and thus the person with that DNA is immune to HIV.
The doctor implanted those two zygotes into a woman and she bore two kids, who are - as to my knowledge - alive and healthy.
Please bear in mind that, while being able to prevent someone from getting HIV sounds great, there might be side effects, that were not anticipated. And don't even get me started on why this was ethically and morally a very serious issue.
taken by Raymond Gosling
Yeah science!!!
😎👍
I’m taking intro to Biotech for the summer 😅
wow, he makes science sound so amazing!!!!!!!!!
Thanks!
Epigenetics Rules All!
Thanks man! This helped me alot
0:15, don't u mean, what is love?
Baby don't hurt me
Thank you
Good very good ❤
Beautiful work!
You people have not included any information about HARGOBIND KHORANA .
Yeah, Watson seems like a jerk.
It is ironic and interesting that the movement of Earth around sun is also double helix.!
Ironic?
İsn't it a single helix? O_o
I actually work at a biotech company hehe
What do you do?
excelente video, magnificas las graficas usadas
10:32 by the way, that is where Michael Crichton got the idea for his novel Jurassic Park.
can we pls get a redo of biology
Awesome
DNA is the machine language that makes the assembly language of RNA, I feel like that's a comparison I should have heard before today
that's not how any of those work
Yeah but you'd think I would have at least hear it before
10:15, wrong left-handed DNA :/
Called it
I did a big history project about Rosalind Franklin and it was really interesting. It's horrible how she was treated by her colleagues, and if anybody thinks that James Watson is a hero I'd recommend doing some research.
If you have crash course games why don’t you try crash course anime. You could teach people the oldest anime ever and how anime evolved to how popular it is today
Woderfull
I thought you started with 'Let's talk about T&A, and Biotech."
And I was like, sure, not what I expected form the video, but OK.
Need more John and more world history asap
There's some plain incorrect statements in this video:
1. Franklin did NOT make Photo 51, it was made by one of the students in her Group, and was thus automatically credited to her
2. The photo didn't get outright stolen, wilkins showed it privately, which was quite the mistake on his part
I didn't watch the video much further than this, since it was already too incorrect and opinionated at that point.
So, if a discovery is made by a head researchers' team, that discovery should not be credited to the researcher?
@@BalthusHomewood It should be credited to both the Person who made the discovery, and the supervising head researcher - only giving credit to Rosalind Franklin is wrong, but only giving credit to Ryan Gosling would be wrong aswell.
Both are very vital to the creation of the Photo, so both should be credited appropriately.
i read a book "siddhart mukherjee the Gene" it goes along the line of what you are saying. Sci show unfortunately has very opiniated facts.
Woah, DNA!
GATTACA
Billy Trespassers good movie
remember, it's not cursing if you're an atheist.
The video was great, but I wish I could have heard DNA a few more times. Hank, why don't you take it again and really explore the studio space?
Educational!
Life is a cocktail of pain, disappointment and boredom.
Every time he say chromosomes i get TvFilthhFrank vibes
Joegress Shinka!
I can excel at anything if I take it very seriously.
Why humans today dont have multi colors like scientist in the pictures ?
DNA emoji soon.
You should do one on music and nmusic history and that kind of thing!
Are ignoring Tesla on purpose?
YOOOO BROTHER WHATS DOWN CHIEF
next: BOW
💡💡💡💡💡
Two episodes to end ? :(
Hallo Bcasians
Anyone know why hydrogen has a crown? Lol
The birth of IVF? Don't you mean the birth of the birth of ME?
(I'm trying to say 'that sounds interesting because I'm an IVF baby')
Lovely!
nk 8,30
11,40.
10:12 - Nicolas Cage?
Honesty in school they teach you a lot of things useless such as this, but teachers might say we are showing you different things so you might know what you want to do in the future. something along the lines of that. But making me do work i don't like such as this stuff makes me less interested in this stuff and makes me less likely to want to do more things in school, and i think many other students could agree. so dont reply completely hating me, tell me any other claims of why people should learn things useless in school and i already heard to expand knowledge but that idk what major value will that have in someones life on not even a daily maybe not even a weekly basis, i mean usually student forget things they learn in classes like science after summer. so whats the point?
lmao "sexist jerk" got me rolling
The pronunciation of Schrödinger is killing me... Other than that great video :)
Me too. Could someone please tell Hank how to pronounce the names of foreign scientists?
Schr-ow-din-jer... That name comes up a lot, you should look up how to pronounce it.
3:26 in fairness to Watson he is also so astonishingly racist that almost no one is still willing to publicly associate with him.
Is а person from video scientist?
Thanks for trying to make it fun but..you could... add other extractions from videos or edit in your own instead of droning on and on its kinda boring
Sorry I don’t speak sci-fi writer
I am short
Third comment
weird flex but ok
all life came from God.
First
guys it’s this one definitely
how can he mispronunciate all the German names like that? is it on purpose for an inside joke? I can't believe that guy can't say correctly "Schrödinger" after he has been watching The Big Bang Theory for 10 years....
I have never seen someone move as they talk as much as he does.
first to comment
Not first :,(
You talk too fast.