Lipid Lowering Agents (Cholesterol Drugs)

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[@madinaradjabova1668]

HM*G (good for) *CO A (coronary artery)

[@rachael4775]

this is literally the most brilliant little trick ever my jaw is on the floor hahha

[@ruzan6386]

Genius. Will never forget this

[@TheRyanChang]

for PCSK9 inhibitors
Pesky (PCSK-9) muhammad ali (ALIrocumab) Evolved (EVOlocumab) boxing.
This also helps us remember the side effects because you have NEURO effects and soreness (mylagias) from boxing

[@nehadharap700]

ahhh,THANKS DUDE!

[@ruzan6386]

Thank you!

[@erikramos1972]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@justaryana]

Dirty, you did it again. you really did do a better job teaching this than ANYONE else. and in the nick of time for my exam!

[@tesnimhamdan5813]

My exam is in 2 months and your videos are so essential during this period. You just simplify everything, especially pharma which is so hard to memorize. I watched your video on HIV drugs and I answered the UW questions like it was nothing. Now I guess the lipid lowering agents will be a piece of cake as well. Thank you so much!

[@yashpawate1306]

Perfect time for my pharm test tomorrow. Thank you so much!

[@user-eb3ni4bz9q]

Dude, you're like a magical teacher that I go to when ever I stuck in a subject.

[@fireman00742]

Dirty medicine is by far my favorite learning tool. I have not purchased a text book in my FNP program yet. Thank you !!!

[@georgiabessie]

How’s school going? I’m in year two FNP. I love these videos.

[@palomiichimplin2855]

Thank you so much for your support 🇪🇸👏🏽👏🏽👏🏽

[@uswahsiddiqi238]

Thank you so much! Will definitely support via membership once I start earning! THANK YOU

[@yummy1857]

It’s a measure of how interesting your videos are when I’m watching them on my break after exams lol

[@VivaLaVittoria]

Great video. I'm currently studying to be an FNP and your content gives such great overviews of different content areas.

[@doom_inik]

exam in 10 days, coming in clutch with this topic cause first aid had a lot going on with those visuals (same with sketchypharm), but you made this v easy to follow👍

[@sanjananayak4348]

Thank you so much! You have no idea how much anxiety this topic gave me before this video.

[@hehateme1187]

To remember the ↓ LDL exceptions, Fibrates and Niacin, I added this little mnemonic:
fibra↓Tes (↓ TG) and "Nancy is extra Hot!" (Niacin - ↑ HDL - flushing)
For remembering the majority decrease LDL, I remember "All the fatties drop it LOW LOW" (Lipidemia drugs ↓ LDL lol)

[@shanazannaleeguptar8075]

I used your channel and I passed pharm 1, using rn to see if i can pass pharm 2, great work sir

[@sarasims2207]

really was the best explanation i ever heard thus far ! :)

[@hivalee6992]

might be your best video

[@ekrajghai6525]

Thank you so much dirty medicine! Watching your videos makes me forget all the other resources Im using.

[@obeymadzingo6152]

thanks for the table at the end!

[@lauraliranzo]

WOOOOOW thank you so much! much love from DR

[@tjm1434]

Just what I needed. High-yield.

[@nola-baissa2433]

Great video as always. What about Thiazolidinediones?

[@anacarolinacostapontes5506]

Hi!!! Greetings from Brazil! I love your videos! They are incredibly objective and accurate! I just wanted to say thank you so so much and please keep it up! Also, just a small correction: estatins are actually competitive inhibitors and not alosteric inhibitors: they bind to the active site of the enzime HMG-CoA-redutase, taking the place of the substrate HMG-CoA, as opposed to binding to the allosteric site and inducing a conformational chance of the enzime that makes the binding of the substrate to the active site impossible.

[@nurula1783]

running out of things to comment in your videos but they really are helpful

[@ksharma103]

Much needed!!!!

[@MedManiac1]

thank you for saving my life!! 😭😭❤️❤️

[@veenaveena797]

Your teaching method helps to register and retain facts...

[@JaehoonWrestling]

Your lecture is so easy to understand and ty for your contribution!!!

[@bitewmekonnen5862]

what an awesome explanation!!

[@RidaZayn]

The best explanation, Thank you 👍

[@umairjaved4755]

@Dirty med my exam is next month. Kindly upload one video on Adrenergic system.
P.S: Thank u so much for every video. May God bless u for that

[@ann26614]

Thank youuuu so much!!! THIS literally saved me!

[@GabrielSantAnaCarrijo]

In portuguese they translated "Bile acid resins" to "Bile acid kidnappers" which is just 1000% better

[@mariamshabbir198]

Amazing Lecture!

[@usmanwisa3386]

Excellent explanations

[@shen3998]

Amazing work dude 👍keep going

[@vietle1313]

this man the goat

[@maryemmallick2752]

you promised making it easier for us and you kept your promise. KUDOS😍😇

[@25lizfair]

Thank you for the video! one thing to clarify...don't fibrates also increase HDL? via PPAR-a? the take-home points at the end only point out that niacin increases HDL, and that fibrates just reduce trigs

[@duocphamtruongtho4462]

Its so helpful, thanks so much!

[@deeeeep806]

super helpful video, thank you!!

[@user-vt5eg5zj1e]

Thank you very much bro. 🥰

[@drdianellyspintobenamaraap5935]

love this channel

[@omnasharma955]

Could you please make a video on diuretics? Thank you

[@manjushreeinamdar1242]

Thankyou God sent angel

[@professorcensored3647]

9:47 "but who cares?" cracked me up. Thank you

[@Army_Dentist]

Dirty you are super clean with concepts🎉😅👏🏻

[@uzmabaig465]

Thank u so much for this video

[@priyam1550]

Thank you!

[@xaaboopinkly]

Thanks sir!

[@jhalajayraj130]

Life saver video

[@Nishamukherjee1995]

Thanks a lot sir

[@dream_catcher430]

Thank you very much 🙏

[@alih6953]

Thanks

[@nasimmalakoti7031]

You're amazing

[@moji1466]

Not the nerdy academic career 😂 ! Great video

[@moob2020]

Can you please upload a video about opthalmology (especially fundoscopic images )

[@sdnyanzi]

No

[@garrettmorgan9926]

Thanks Dirty! Mnemonics: NPCs are Eze. LFTs are Eze. EzetimIBe Intestinal Brush border.

[@yaalia.s9033]

cant thank u enough

[@TheRebellefleur27]

thank you

[@adaezenwankwo6754]

This guy is good

[@drmoctarali7385]

From somalia you are one in billion

[@williamkudiewu1032]

Dirty is crazy man love this guy

[@Azhrxy]

So thank y dr.

[@beatriz.e.m7545]

hey just a question because you had said the Fibrates second pathway via PPAR a increases the HDL: which would mean that HDL would be increased for both Niacin and Fibrates how come you only put a decreased quantity of triglyceride in fibrates?

[@josephakalonu1052]

HDL would be increased by Niacin only.

[@grace_cee9335]

Thnk u so so much

[@ahmadcheema7198]

Thank you ^_^

[@thesweetpotatogirl]

Thnk you🌟🌟🌟

[@omerhaseebkhan]

salute to u

[@globularfish2074]

You can use "NPCs wearing TIMs are at the IBorder" for the ezetimibe if you need a mnemonic

[@shanemckenzie8681]

Not being mean bro, but your voice soothes me to 😴 stay awesome

[@meethamallawati850]

Please come and teach at our college

[@bandanaghimire6427]

Good

[@lauraliranzo]

You are theeeeee besssttt!

[@zorrento14]

My exam is in June and I'm clenching my pearls rn

[@Kittendoc]

Same

[@HuevoBendito]

Mine's in July. We got this!

[@elizabethdean1209]

Thank you for your incredible generosity in the work you do! You are making the world a better place in a big way! Have you ever considered a life time membership option? I would love to support your work and my ongoing education for life. Dr. Been has the option of one time payment for unlimited access and I love the idea! ✌️ Liz Dean

[@AhsanKhan-wo2ql]

Its the mnemonic juicelord himself

[@mohannedjamal9471]

amazing, just wanted to mention that resins can increase TGs by increasing VLDL

[@johanlalnunmawia3818]

Wow ! Really 😲

[@zuhramuskan5563]

HOW?
WILL YOU MIND TO EXPLAIN IT

[@AN-zg3sr]

Cholestrol is not bad it's the oxidised lipids which are nd in presence of glycation..the combination results in CVD

[@padmajahawaldar4319]

Thank you dirty ❤

[@graywolf2600]

Do you have a source on the dementia adverse effect?

[@DirtyMedicine]

Bottom line seems to be that FDA was concerned enough about cognitive changes. Be it statistically significant or not, it is worth knowing about imo:
link.springer.com/article/10.1007/s40264-015-0296-6
www.ahajournals.org/doi/epub/10.1161/CIRCRESAHA.118.313238

[@arizonablossom8635]

Thanks a lot dirty medicine🙏

[@darkmoon3646]

DIRTY U FREAKING LEGEND

[@puneetgill4994]

💯

[@unicornspoops]

Sketchy pharm is insane for this topic. It explains the physiology but its convoluted and difficult to remember bc of that. I'd say dont bother with it and use this with FA instead.

[@TheGhadaelarbash]

Note: PPAR-Gamma was mentioned in the insulin drugs "Bring Glitta to the party"...Glita was the drugs of TZDS and Party MoA

[@nigelwang2447]

Primates bring stones to the PPARt-ay 😂

[@Angielle_]

❤❤

[@user-sb1ku5hq7h]

Love from Russia 🎉

[@joshmcgoo]

commenting for the algorithm

[@deadricchampion6856]

Based Dirtymedicine

[@jamesgordon8867]

Where is Chromium?

[@sleepytraveler369]

No mention of gallstones with bile acid resins? Wtf dirty

[@Lights0ut]

Find the odd one out
1. Atorvastatin
2. Simvastatin
3. Nystatin
4. Rosuvastatin

[@TusharMathapati.]

Nystatin because it is antifungal and others are not

[@UsmleAspirantPediatrician]

What I think is that although you eat fibers so that you don’t get POOP STONES, FIBRATES make you stones 🧐

[@kayallen7603]

statins = yuck.

[@neya732]

thank you so much dirty

[@MatanLinevitz]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@amanydubai7880]

Thanks