Anticholinergic syndrome (mechanism of disease)

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  • Опубліковано 24 кві 2023
  • This is a flowchart on anticholinergic syndrome, covering the etiology, pathophysiology, manifestations, and management.
    ADDITIONAL TAGS:
    Tachycardia
    Risk factors / SDOH
    Cell / tissue damage
    Nervous system path
    Anticholinergic syndrome
    Medicine / drugs
    Infectious / microbial
    Biochem / organic chem
    Immunology / inflammation
    Signs / symptoms
    Tests / imaging / labs
    Environment / toxins
    Genetics / hereditary
    Flow physiology
    Pathophysiology
    + Management
    Etiology
    Manifestations
    Systemic blockage of acetylcholine →
    ↓ parasympathetic nervous system
    ↓ involuntary smooth muscles movement in:
    Gastrointestinal tract
    Urinary tract
    Lungs
    Sweat glands
    Arteries
    Dry mouth
    Thirst
    Constipation
    ↓ bowel sounds
    Paralytic ileus
    Urinary retention
    Warm, dry skin
    Eye
    Flushing
    Midriasis
    Photophobia
    ↑ intraocular pressure
    Glaucoma
    Confusion
    Agitation
    Delirium
    Belladonna poisoning: toxic leaves and berries contain atropine and scopolamine
    Jimson weed / Angel's trumpet (Datura stramonium) poisoning: also contains atropine and scopolamine, causes "gardener's pupil"
    Drugs that are primarily anticholinergic agents
    Drugs with anticholinergic properties / side effects
    Atropine
    Benztropine
    Trihexyphenidyl
    Tricyclic antidepressants (predominantly doxepin, amitriptyline, imipramine, and trimipramine)
    First-generation antihistamines (e.g., promethazine, dimenhydrinate)
    Reversible acetyl- cholinesterase inhibitor
    Physostigmine
    Don’t use with TCA ingestion → asystole
    Hallucinations
    Antipsychotics (clozapine, quetiapine)
    Anticholinergic delirium

КОМЕНТАРІ • 4

  • @MsJazznalex
    @MsJazznalex 9 місяців тому +1

    I have a some with developmental disabilities and PANDAS , our new MHNP thinks our son experiences anti cholingergic syndrome without the meds OD being a issue, this video helped me to understand a lot!

  • @malcolmjelani3588
    @malcolmjelani3588 5 місяців тому +1

    This is an intelligent way to group things and organize information. one could create flowcharts, organized by color and expand on information with flashcards. What app allows you to make the flowcharts?

  • @littlemountaintotherescue8954
    @littlemountaintotherescue8954 Рік тому +1

    Gracias amigo

  • @mikewoo7999
    @mikewoo7999 Місяць тому

    What program is this?