Ketamine Could Treat Depression (Dr. John Krystal Interview)

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  • Опубліковано 23 гру 2024

КОМЕНТАРІ • 148

  • @lilys7431
    @lilys7431 2 роки тому +21

    I have fought depression for so long, can’t even imagine what it would be like to wake up with a non depressed brain.

    • @Kuro_Tsuki
      @Kuro_Tsuki 2 роки тому

      Hoy, I feel ya...

    • @jeremytrajkoski6111
      @jeremytrajkoski6111 2 роки тому

      Yeah . Me too

    • @sandyjohnson5111
      @sandyjohnson5111 2 роки тому +1

      I was there also, for what felt like my entire life. I also got to the point where I believed suicide was an option, because why should I be forced to continue trying to survive feeling this horrid pain. Don’t give up TMS is an option that insurance is starting to cover. It sounds like this ketamine works also. While I haven’t seen this covered under most insurance, it maybe in the future.

    • @kimberlydragone6015
      @kimberlydragone6015 2 роки тому

      @@sandyjohnson5111 yes so sorry. therapist are required to talk you down off the bridge of course, but it feels unfair for them to insist you stay and endure such pain day in and day out. It’s absolute torture. I’m sure the constant cortisol that courses through my body is cutting my life short anyway.

    • @solarmoon33
      @solarmoon33 2 роки тому

      If you haven't already, consider dietary changes. Have had depression on and off for like 2 decades, found out recently a lot of it is related to my gastrointestinal health. GI health and mental health is definitely related in some people's cases.

  • @kittyconnell8842
    @kittyconnell8842 2 роки тому +18

    I just finished 12 Ketamine sessions and can say that they helped me more than a lifetime of meds that either did not help or made me suicidal. Ketamine is a game-changer. I think that psilocybin is also very helpful. Thank goodness these meds are available for us.

    • @kimberlydragone6015
      @kimberlydragone6015 2 роки тому

      Out of pocket or did insurance help you? …If you don’t mind

    • @cocoknows
      @cocoknows 2 роки тому

      Same! I have become an evangelical for ketamine therapy!

    • @kittyconnell8842
      @kittyconnell8842 2 роки тому +1

      @@kimberlydragone6015 - Out of pocket. I worked with a program that offers sublingual Ketamine therapy at home. It is much less expensive than IV Infusions, and it worked for me.

    • @sandyjohnson5111
      @sandyjohnson5111 2 роки тому

      @@kittyconnell8842 So is your depression in total remission? Is it something you have to continuously have or do a series of infusions result in remission? I too, am so grateful new treatment options are now available for treatment of depression. I truly got my life back. I’m sure without a doubt, I would be on disability and unable to work if I hadn’t found the TMS therapy. I’m just always afraid the treatment will stop working. Good to know there is still another option out there for me.

    • @kittyconnell8842
      @kittyconnell8842 2 роки тому

      @@sandyjohnson5111 - No, the depression is not in total remission. The ketamine helped immensely, though, and I'm functioning at a much higher lever than I was before the treatments. I suspect that I will need an occasional "booster" but it was definitely worth the expense to get the help.

  • @sandyjohnson5111
    @sandyjohnson5111 2 роки тому +11

    I live with treatment resistance Major Depressive Disorder. Two years ago I was ready to try ECT and go on disability. My psychiatrist had just start treating his patients with rTMS. This is a game changer. It’s FDA approved and covered by most insurance (including Medicaid and Medicare). It’s non invasive and you don’t even need to miss work. It’s a series of 20 minute sessions 5 days a week for 11 weeks. After the first series, my depression was In total remission. It was at the beginning of the pandemic and I had an ungodly stressful job. I ended up have a second series. It’s been about 18 months and my depression is still in remission. This doesn’t mean I don’t have a bad day now and then, but it’s not devastating. rTMS therapy has been around and FDA approved for well over 10 years. It just takes a long time for insurance companies to see a cost benefit. I do think on down the road ketamine infusion will be covered by health insurance.

    • @kimberlydragone6015
      @kimberlydragone6015 2 роки тому

      So glad it’s helping you 😊

    • @matthewgiannotti3355
      @matthewgiannotti3355 2 роки тому +1

      rTMS is great, unless you need to remember things. It causes horrible memory loss for many people. Ketamine saved my life and I do not have memory problems. Ketamine is also fda approved and covered by most insurances. I am happy that worked for you though.

    • @sandyjohnson5111
      @sandyjohnson5111 2 роки тому

      @@matthewgiannotti3355 Really. The only side effect I had was a bit of dizziness afterwards. While ketamine infusion clinics are popping up in the area I live in, I haven’t seen any insurance that covers it yet.

    • @mulatso7959
      @mulatso7959 2 роки тому

      I'm struggling too with a treatment resistance major depressive disorder, I just started a psilocybin assisted therapy, and I really hope it all gets better. I'm really happy that your therapy worked for you! My best wishes.

    • @sandyjohnson5111
      @sandyjohnson5111 2 роки тому

      @@mulatso7959 Don’t give up. There are so many treatment options out there today.

  • @cocoknows
    @cocoknows 2 роки тому +3

    Thank you for talking about this! I have been doing Ketamine treatments for about 9 months and it has changed my life!

  • @WM-ln4dz
    @WM-ln4dz 2 роки тому +23

    Unfortunately, ketamine treatment is thousands of dollars for an entire course, and not covered by insurance.

    • @thesultrystrangerdanger6824
      @thesultrystrangerdanger6824 2 роки тому

      We can work something out 😱😱😜🧐😭🥳👻

    • @dogloversmith7139
      @dogloversmith7139 2 роки тому

      It’s my understanding Ketamine is only recommended for long term debilitating depression.

    • @oxymoron5167
      @oxymoron5167 2 роки тому +1

      @@dogloversmith7139 I’d recommend anyone take it at least once in their life. It’s eye opening and may put things in perspective for some, plus it’s cheap and readily available. It’s not physically addictive either 🎉

    • @parkestanley2436
      @parkestanley2436 2 роки тому +3

      I just called my insurance United Healthcare, they cover 67% of the cost of ketamine. I have an appt with a psychiatrist this coming Thursday

    • @Aashka_The_Mystic
      @Aashka_The_Mystic 2 роки тому

      True and you have to keep getting it.. I did it but it didn't really help

  • @scottsmyth87ss
    @scottsmyth87ss 2 роки тому +2

    Thank you for this, David.

  • @bradswanson6788
    @bradswanson6788 2 роки тому +17

    Should have a follow-up discussion regarding the benefits of treating depression with psilocybin. Interesting times now in this field...

    • @TheNotSure
      @TheNotSure 2 роки тому

      MAPS has been working on psychedelics for years. A lot of research.

    • @TheNotSure
      @TheNotSure 2 роки тому

      @@djancak That's not true at all. Try to actually READ the studies. Or look up MAPS. Don't be spreading bullshit.

    • @FleurPillager
      @FleurPillager 2 роки тому

      Should be telling people how effective, safe and inexpensive generic SSRI and SNRI medications are at treating clinical depression and other psychiatric disorders for most people.

  • @sebastianfelipe515
    @sebastianfelipe515 2 роки тому +5

    I can't find a source anywhere for any good psychedelics in my area, I suffer some pretty bad depression and i got a chance to try K and man it was a miracle substance, I felt free,the only high or euphoria was from the relief of my vices being released, that's exactly what it did

    • @johnkeleher5563
      @johnkeleher5563 2 роки тому

      The psychedelic experience is temporary but many people have permanent results

    • @fluffypineapples8852
      @fluffypineapples8852 2 роки тому

      Mushroom completely turned my life around and my anxiety and panic attack disappeared and my personality changed into a much more generous loving person

    • @evelynbecker4916
      @evelynbecker4916 2 роки тому +1

      Check
      (doctor_mckenzie)
      He's got psych's

    • @lisadavidson1523
      @lisadavidson1523 2 роки тому

      I had 3.5 grams dried lemon tek most beautiful experience ever!!

    • @fluffypineapples8852
      @fluffypineapples8852 2 роки тому

      @@evelynbecker4916 Is he on on Instagram or what?

  • @StreetLore
    @StreetLore 2 роки тому +11

    I actually just finished my ketamine treatments and I have to say it was absolutely incredible I did 4 treatments

    • @StreetLore
      @StreetLore 2 роки тому

      Also just started a new approved drug that simulates the same mechanisms of ketamine

    • @doctorthirteen1700
      @doctorthirteen1700 2 роки тому +1

      What's the cost? Does your insurance cover it? I'm just curious and have been considering it.

    • @7mike2300
      @7mike2300 2 роки тому

      What changes have you noticed?

    • @StreetLore
      @StreetLore 2 роки тому +1

      @@doctorthirteen1700 at this point insurance doesn’t cover it. It was $400 a session.

    • @StreetLore
      @StreetLore 2 роки тому +2

      @@7mike2300 immediate hope. I would say it pulled me out of one of my darkest times really quickly

  • @7mike2300
    @7mike2300 2 роки тому +3

    Been looking into this recently. Thinking about setting up my sessions for the beginning of next year.

  • @djignatin4043
    @djignatin4043 2 роки тому +3

    Thank you for bringing this up David. I am studying for my Masters in Psychology. I have heard about this.

  • @bettyveronica9880
    @bettyveronica9880 2 роки тому +3

    Extremely interesting topic. David, more neuroscience topics and please allow for longer duration. Thank you, sir!

  • @FleurPillager
    @FleurPillager 2 роки тому +1

    I'm concerned that media in general does not talk about current, effective, inexpensive available medical treatments for clinical depression and other psychiatric disorders. SSRI's are effective for most people who take them. It makes me wonder if they aren't telling people to call their doctor because most SSRI's are now off patent and available in inexpensive generics. It seems that once the pharmaceutical companies stopped profiting from them they switched media messaging to experimental alternatives.

  • @matthewgiannotti3355
    @matthewgiannotti3355 2 роки тому +1

    The title of this video should be "Ketamine Does Treat Depression". Ketamine saved my life, I have been receiving ketamine treatment for over a year.

    • @FleurPillager
      @FleurPillager 2 роки тому

      Great as long as they exhausted the many less expensive, evidence-based, decades of long-term use with great safety record medications first. SSRI's and SNRI's are effective for most people.

  • @avaz5490
    @avaz5490 2 роки тому +2

    Thanks for doing this segment. It was very enlightening and interesting.

  • @reddawn2031
    @reddawn2031 2 роки тому +4

    I do ketamine and it's a lifesaver.

  • @kimberlydragone6015
    @kimberlydragone6015 2 роки тому +3

    I was a subject in the Yale ketamine study about 8 years ago. It was quite lengthy and had some painful and very uncomfortable parts to it. Unfortunately, I was disqualified when my BP went up and stayed up after they tried putting a massive/ painful intravenous line in my arm, missed and I was bleeding profusely. I was more upset that they let me go after I had almost completed the study. I have non-responsive/ treatment resistant depression and so much wanted to see if ketamine would help me. Sadly, I didn’t get that far. 😢

    • @kimberlydragone6015
      @kimberlydragone6015 2 роки тому +1

      @@djancak thank you. Been living like this for decades. Daily, I wonder why I should stay. It’s very very dark and not much of a life at all.

    • @cocoknows
      @cocoknows 2 роки тому

      It's dangerous if you have high blood pressure, unfortunately. It's best you didn't continue with it. I'm sorry you had that experience, though. I'm also sorry that you are still suffering from depression.

    • @Kuro_Tsuki
      @Kuro_Tsuki 2 роки тому

      @@kimberlydragone6015 I feel that. I've had seizures and severe anxiety and depression since the age of 15.
      Almost hitting 40, and haven't been able to support myself my entire life. Thank goodness for the Canadian health care system, or I'd have been done with it all a long time ago...

    • @kimberlydragone6015
      @kimberlydragone6015 2 роки тому

      @@cocoknows thank you. I don’t know if the Ketamine is dangerous for high BP, but high BP was a symptom that knocked me out of the study. My BP is pretty much under control now, depression anxiety is not. 😔

    • @kimberlydragone6015
      @kimberlydragone6015 2 роки тому

      @@Kuro_Tsuki I’m so sorry. yes that’s my story as well, sans seizures and add 20 years. Keeping employed is always a problem. Currently no income and wondering how I’m going to survive.

  • @marypike8149
    @marypike8149 2 роки тому +2

    David thank you for doing a segment focusing on mental wellness. IMO we'd be foolish to ignore new information/technology; I find no wisdom in refusing to consider any & all healthy alternative approaches.

    • @FleurPillager
      @FleurPillager 2 роки тому

      Most people respond well to older medications like SSRI's and SNRIs. They are now inexpensive and not profitable for a certain industry which is why we are seeing so much advertising for expensive experimental alternatives.

  • @lorikendrick5076
    @lorikendrick5076 2 роки тому

    Thank you for this. I will be talking to my doctor about this treatment

  • @Dax893
    @Dax893 2 роки тому +2

    A lot of narcotics could help with depression. I don't know why this is news, but at least David is starting the conversation.

  • @MaJoRMJR
    @MaJoRMJR 2 роки тому

    As someone who is related to someone who has suffered from extreme depression, the drugs don't work, because they don't get to the root cause of the problem, you need to address the cause otherwise progress cannot be made, drugs alone are a waste of time, they just level out the extreme ends of ups and downs. Cognitive therapies are the best solution.

    • @FleurPillager
      @FleurPillager 2 роки тому

      That is incorrect. Cognitive behavioral therapies are not first line treatments for major depressive disorder, bipolar disorder or schizoaffective disorder. Medication is.

  • @kahetiger
    @kahetiger 2 роки тому

    Is this primarily just for depression? I’m Bipolar 1 and what my psychiatrist calls a ‘rapid cycler’. I can go from depression to mania throughout the day or sometimes depression for a few days, back to mania and so on.

  • @fieldandstream9362
    @fieldandstream9362 2 роки тому +1

    If it works it will be incredibly expensive and not accessible to those who probably need it the most.

  • @tylerhackner9731
    @tylerhackner9731 2 роки тому +1

    Interesting interview

  • @ronward3949
    @ronward3949 2 роки тому

    Going back to voluntary/involuntary muscles, autonomic responses versus voluntary muscle responses and those underlying Nervous systems response to the drug's effects, on board, until those effects begin to recede and allow for physical re-coordination efforts followed by additional voluntary muscle control continues in drugged Individual.

    • @liveandletdie7187
      @liveandletdie7187 2 роки тому

      Well antidepressants are worse and very deadly..

    • @ronward3949
      @ronward3949 2 роки тому

      @@liveandletdie7187 keeping check on my own Health, Peace out!

  • @TheBumpdjs
    @TheBumpdjs 2 роки тому

    Gd interview! More like this please

  • @FleurPillager
    @FleurPillager 2 роки тому

    What is "depression"? Doctors treat medical conditions like bipolar disorder, major depressive disorder and other psychiatric disorders not "depression". Depression is a mood and all psychiatric disorders have multiple symptoms independent of simple mood. Any good doctor would list all of the symptoms and tell people to call their doctor because there are many effective medical treatments right now. Exercise and diet alone are not an effective treatment for any psychiatric disorder and if you have any good research to the contrary I'd love to see it.

  • @jeffafa1730
    @jeffafa1730 2 роки тому

    What about PTSD? I could see the application there.

    • @cocoknows
      @cocoknows 2 роки тому

      Yes, it's very effective for otherwise untreatable depression, anxiety, *and* PTSD. I have been using it for PTSD and have had amazing results.

  • @FDLrick
    @FDLrick 2 роки тому +1

    I've been on Sertraline for over 30 years now, I'm so thankful it has worked for me. The problem is, if I'm off of them for over 2 to 3 days, it seems like an electrical shock is going through my brain and it's kind of like grabbing onto an electric fence. It lasts only a second but, repeats itself more and more if sertraline hasn't been taken. As soon as medication is taken, within an hour or so, the shocks disappear. I talked to the Dr. at the VA and he states he knows the problem exists but hasn't an answer what's causing it. Could you please help me out on this one. Thanks, Rick

    • @clintparsons3989
      @clintparsons3989 2 роки тому +1

      If it's worked for thirty years I wouldn't mess with it. Take it like you're supposed to and problem solved.
      I take Pristiq. Bad electrical shocks if I miss one pill. I just take it every day.

    • @oxymoron5167
      @oxymoron5167 2 роки тому +3

      My partner has this too, she’s coming off very slowly. I’m not a doctor but would suggest it’s nothing to worry about as long as you reduce slowly

    • @liveandletdie7187
      @liveandletdie7187 2 роки тому

      It can take many many years to get off of any antidepressant.. They are deadly

    • @FDLrick
      @FDLrick 2 роки тому

      @@liveandletdie7187 Today you can go to the local herb shop and pick up some pretty good shit. It works for me.

    • @liveandletdie7187
      @liveandletdie7187 2 роки тому

      @@FDLrick what is it ??

  • @iConformed
    @iConformed 2 роки тому

    I tried ketamine therapy for my clinical depression. Didn’t work for me unfortunately but ketamine is a hell of a trip!

    • @Aashka_The_Mystic
      @Aashka_The_Mystic 2 роки тому

      It was, I hated it actually

    • @iConformed
      @iConformed 2 роки тому

      @@Aashka_The_Mystic I loved it but I can see how it’s not for everyone, it’s pretty intense

    • @cocoknows
      @cocoknows 2 роки тому +1

      I'm sorry that it didn't work for you. I have had life changing results.

    • @iConformed
      @iConformed 2 роки тому

      @@cocoknows thanks, really glad it helped you! It sucks being treatment adverse, I’ve tried pretty much everything with no effects at all. It’s ruined my life, hoping I can bounce back eventually!

    • @cocoknows
      @cocoknows 2 роки тому +1

      @@iConformed I hope you are able to find relief soon.

  • @Aashka_The_Mystic
    @Aashka_The_Mystic 2 роки тому +1

    It didn't work for me.

  • @johnwilliams2247
    @johnwilliams2247 2 роки тому +1

    Been doing it for over three years now.....night and day improvment!

  • @youdontseeanoldmanhavinatw4904
    @youdontseeanoldmanhavinatw4904 2 роки тому

    My mother treats her PTSD with ketamine.

  • @dreamsofhallerbos5261
    @dreamsofhallerbos5261 2 роки тому

    Ketamine is effective for pain, CRPS, Intractable Chronic Migraine, Fibromyalgia.

  • @blenderstuff9191
    @blenderstuff9191 2 роки тому

    That would make Yoda the happiest creature ever

  • @ptv1856
    @ptv1856 2 роки тому

    👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽👽😖

  • @gavingleemonex3898
    @gavingleemonex3898 2 роки тому

    Unwise.

  • @ronward3949
    @ronward3949 2 роки тому +1

    Animal tranquilizers basically in general historical record.

  • @DharmaPunk111
    @DharmaPunk111 2 роки тому

    Not a fan of ketamine. Psilocybin is much better in my opinion.

    • @DharmaPunk111
      @DharmaPunk111 2 роки тому

      @@djancak no. It could just be me. Psilocybin works really well for me and I've never had a bad trip with it but everyone's different so I wont judge

    • @cocoknows
      @cocoknows 2 роки тому

      Better for you. However, there are many reasons Ketamine can be better for some people.

  • @Hagbard1138
    @Hagbard1138 2 роки тому

    Drugs man.

  • @SneakySteevy
    @SneakySteevy 2 роки тому

    Adequate thoughts also treats depression

    • @jesnoggle13
      @jesnoggle13 2 роки тому

      You win the dummy award.

    • @SneakySteevy
      @SneakySteevy 2 роки тому

      @@jesnoggle13 You have all the rights you want to have inadequate thoughts if you prefer to. It’s your choice your life man!

    • @SneakySteevy
      @SneakySteevy 2 роки тому

      @@djancak the ones that are in concordance with your values, needs and nature.

    • @SneakySteevy
      @SneakySteevy 2 роки тому

      @@JustADudeGamer it has everything to do. It’s not the way that you think that you must change. It’s the way that you manage your life. Set values, find your needs, respect yourself and your thought will change.

    • @SneakySteevy
      @SneakySteevy 2 роки тому

      @@JustADudeGamer taking dopamine will not solve the core problem.
      Positive thoughts are relative.
      One could say that the idea of missing a day of work to take cocaine is a positive thought because he feel good about it but I doubt that this behavior is in line with his value, needs and nature.
      I encourage you to read « the Spinoza miracle » by Frederic Lenoir. Very good philosophy about Baruch Spinoza, the father of the modern world.

  • @spacey118
    @spacey118 3 місяці тому

    How is it you have 2.5M followers and 5k views… but 290 likes? Oh… bc this is federal propagandaaaaaaaaa pandaaaaaaa