Robertsonian translocation: 21q14q

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  • Опубліковано 29 вер 2024
  • What's the chance that a man with a 21q14q Robertsonian translocation will have a child with Down's syndrome?

КОМЕНТАРІ • 85

  • @haseebali2164
    @haseebali2164 2 роки тому +35

    This is THE best lecture on Robertsonian translocation. So much better than most resources even paid ones.
    You deserve all the appreciation.

  • @blazejp0601
    @blazejp0601 2 роки тому

    I've always had trouble visualising Robertsonian transolactions. This did the trick, just in time before the genetics exam

  • @matthewmillett1225
    @matthewmillett1225 4 роки тому +2

    This was super clear and helpful. Thanks for the explanation and drawings!!

  • @kamber95
    @kamber95 7 років тому +2

    Amazing. Very concise. Thank you :)

  • @kevinl1285
    @kevinl1285 Рік тому

    Legend!

  • @IdkaCoolusername
    @IdkaCoolusername 7 років тому +2

    I didn't need this... but great work.

  • @mahmoudelshrbine6218
    @mahmoudelshrbine6218 4 роки тому

    Really helpful .... Thank you 🌸🌸🌸

  • @abdellahezahraoui4774
    @abdellahezahraoui4774 5 років тому

    merci beaucoup

  • @firasbaklouti8757
    @firasbaklouti8757 Рік тому

    is it possible for the meiosis to give an empty daughter cell while the other has all 3 chromosomes?

  • @tahapondsuehara2345
    @tahapondsuehara2345 7 років тому +1

    what about chromosome 2 fusion ?

  • @ahmedsayed9780
    @ahmedsayed9780 7 років тому +1

    Really really brilliant , well done , good work but I think the chances of healthy child will be 1\3 not 2\3 as they r 2 from 6 which equal 1\3 we don't luv maths , I know 😃😃

    • @weteachmedicine
      @weteachmedicine  7 років тому +2

      Thanks for the feedback, sharp! Indeed, the chance of a healthy child in total is 2/6. But the chance that a child that is alive is also healthy is 2/3. Indeed, I could have clarified this more.

  • @samvelaghajanyan4166
    @samvelaghajanyan4166 6 років тому

    1.25x

  • @kaybenjamin6003
    @kaybenjamin6003 7 років тому +39

    This is the BEST explanation I have ever found of this! Thank you!

  • @illainthesky929
    @illainthesky929 4 роки тому +6

    So, the explanation was amazing. I was trying to understand this theme around 1 hour reading, then I found your video and you save me. Thanks :) Greetings from Peru...

  • @thanigeshrajsankar921
    @thanigeshrajsankar921 7 років тому +10

    wow,, ! i hav been scratching my head for many hrs. Thanks for clearing. The best xplaination given by you which i cudn't find in other videos. thank you pal

    • @weteachmedicine
      @weteachmedicine  7 років тому +1

      That's great to hear! Thanks for the feedback

  • @daniel_schmidt.
    @daniel_schmidt. 4 роки тому +13

    There's actually no single german video about this topic. Luckily, the technical terms are really similar in both languages, so I understood it. Thank you for the video, you explained it really well. Have a great day!

  • @tn7773
    @tn7773 День тому

    Ty. So much . U explained it very well...and so sorry fr this but ur writting is very bad😂, and more better if more examples were given like if mother is only carrier, if both parents are carrier and if either parent is carrier of translocation between 2 chr 21....i am writting all th options of my mcq.

  • @caitlinnguyen7254
    @caitlinnguyen7254 Рік тому +3

    Literally best explanation of this ever. Our professor in class did not draw out the gamete possibilities and already had a picture showing them, so I was lost in an instant. Thank you very very very much!!!!!

  • @F91RPG
    @F91RPG 6 років тому +6

    Best video ever! Save my medical genetics exam

  • @AA-nd9fq
    @AA-nd9fq 2 роки тому +1

    I understood this finally,the best explanation, thank you from Egypt ♥️

  • @samsaon7153
    @samsaon7153 2 роки тому +3

    When you go through every possibility everything becomes more clear, thank-you ✨

  • @1rrrrrrrrrrr544f
    @1rrrrrrrrrrr544f Рік тому

    Best explanation, but I have a question, for down's syndrome to occur ,we need three 21 chromosomes, in case of translocation,familial down's syndrome has 2 21 chromosomes, but third one isn't a complete 21 chromosome, are both primary and familial down's syndrome the same?

  • @turinturambar5946
    @turinturambar5946 Рік тому

    Why is there a difference in the chances of a child being born with down syn. as opposed to a living child being born with down syn. being ( 1/6 vs 1/3 ) ? Confused me a little bit.

  • @seraphczx3466
    @seraphczx3466 2 роки тому

    is the proportion of six gametes really equal? I bet there is a difference among them. Really wanna prove it but I graduated and no longer have access to the lab equipment.....

  • @drmahadev5629
    @drmahadev5629 Рік тому +1

    Exactly what i was looking for. Thanks

  • @heba1708
    @heba1708 Рік тому +2

    You say thanks for watching! We are supposed to thank you for explaining like this, thank you 💗

  • @mojtabazare8071
    @mojtabazare8071 3 роки тому +2

    I realy thank you this is perfect

  • @bloodypowerbp5910
    @bloodypowerbp5910 11 місяців тому

    It's true what they say about the Indian guy explaining a topic, amazing

  • @manuelgutierrez6170
    @manuelgutierrez6170 Місяць тому

    You did so great. Keep going, very good explanation!!

  • @florashlaks
    @florashlaks 2 роки тому +1

    Oh my God I cannot thank you enough! You've saved my time

  • @superspeederbooster
    @superspeederbooster 2 місяці тому

    Unfortuantley real life numbers are way different.

  • @tothemoon130
    @tothemoon130 5 місяців тому

    Amazing lecture, thanks!

  • @nourimoudache6886
    @nourimoudache6886 3 роки тому +1

    thanks a million !

  • @manarterea8784
    @manarterea8784 4 роки тому +2

    That was sooooo good !!! ♥️

  • @ahmedal-mahdy4463
    @ahmedal-mahdy4463 Рік тому

    Thank you very much for this absolutely clearful and amazing explanation, i will use it to explain this topic to my colleagues in arabic , thanks.

  • @tuanminhbui633
    @tuanminhbui633 Рік тому +1

    thanks for your fantastic lecture, hope that there will be more in the future!!

    • @Geneesleer
      @Geneesleer Рік тому

      Thank you for watching and for the compliment! Planning on making more videos soon.

  • @Lasitha2
    @Lasitha2 2 роки тому +2

    This is the most clear explanation I ever came across! Thank you.

  • @stijnnuijten8626
    @stijnnuijten8626 4 роки тому +1

    I love you

  • @V99899
    @V99899 3 роки тому +1

    Thank you for uploading this. This is amazing

  • @uzayyolcusu6344
    @uzayyolcusu6344 8 місяців тому

    Wowww thıs iş best

  • @Killer10015
    @Killer10015 7 років тому +1

    Thank you, great explanation, really helpful

  • @CutiePieDIY
    @CutiePieDIY Рік тому

    thank you so much 😭😭❤️

  • @animeboi4010
    @animeboi4010 Рік тому

    Still helpful after 6 years

  • @rotellezG
    @rotellezG 3 роки тому

    I read that there are actually 4 kinds of meiosis resulting cells, because the 14q 21q cromosome is beside the 14 cromosome, and the 21 cromosome is alone, so 14q 21q cromosome can't go with the 14 cromosome towardsthe same side of the cell. Resulting in just 4 kinds of meiosis resulting cells.

  • @alinamandani6117
    @alinamandani6117 Рік тому +1

    Amazing explanation!

  • @1rrrrrrrrrrr544f
    @1rrrrrrrrrrr544f Рік тому

    Great job ❤❤❤❤❤❤❤

  • @paulobispo2197
    @paulobispo2197 6 років тому

    Thank u!! I'm from Brazil and understand perfectly, thank u so very much. 😊

  • @hello.iselima
    @hello.iselima Рік тому

    Thank you for this explanation, you save me

  • @anustinnewsam13
    @anustinnewsam13 7 років тому +1

    Finally helped me understand this!

  • @mohammadfadawi8577
    @mohammadfadawi8577 3 роки тому

    Better of studying book for thousands hours. 👌🏻💙

  • @backstagebaby4701
    @backstagebaby4701 3 роки тому

    Thank you very much! Simply explained and thus well understood!

  • @jessicam9783
    @jessicam9783 5 років тому

    Which Robertsonian translocation would result in 2 out of 3 chances of the baby living? Does the chance vary from different types? Such as if instead of 21 and 14 being affected, 13 and 14?

    • @ambercouch3406
      @ambercouch3406 4 роки тому

      I'm not sure if this answers your question but 14=miscarriage
      13= trisomy 13 and that can result in miscarriage, death shortly after birth or some live years it's really a shot in the dark with that one. Drs say trisomy 13 is incompatible with life but many times that's not the case

  • @sokinahnasser6065
    @sokinahnasser6065 4 роки тому

    Best video 👌🏻👌🏻👌🏻👌🏻💯💯💯💯 ,, highly recommended

  • @naijanerd9572
    @naijanerd9572 3 роки тому

    Thank you sir for this perfect explanation.

  • @Halitsavafoglu
    @Halitsavafoglu 6 років тому

    Amazing! Thank you :)
    What's the chance that a (woman) with a 21q14q Robertsonian translocation will have a healthy child?

  • @Maddawg31415
    @Maddawg31415 2 роки тому

    Super helpful thank you so much!

  • @5omethingsBetterThanNothing
    @5omethingsBetterThanNothing 5 років тому

    channel name didnt age well, but great video!

  • @5omethingsBetterThanNothing
    @5omethingsBetterThanNothing 5 років тому

    channel name didnt age well, but great video!

  • @nourhanahmed5804
    @nourhanahmed5804 3 роки тому

    Thank you for this great explanation.

  • @alizatasnim4702
    @alizatasnim4702 4 роки тому

    Why it only occurs in chromosome 13,14,15,21&22 PLZZ answer

    • @elenimvr
      @elenimvr 4 роки тому +2

      Because they are acrocentric

  • @WikkydGaming
    @WikkydGaming 7 років тому

    Why can't you have all 3 on the same side of meiosis?

    • @WikkydGaming
      @WikkydGaming 7 років тому +1

      In other words, why can't the dad also contribute the 14, 21, and the 14q/21q all in the same sperm?

  • @coxiellaburnetii4034
    @coxiellaburnetii4034 4 роки тому

    Thanx you are the best ❤❤❤

  • @kavitaprabhugaonkar5112
    @kavitaprabhugaonkar5112 6 років тому

    nicely explained.. thank you

  • @miguelorozco4109
    @miguelorozco4109 3 роки тому

    The explanation was very good, thank you!

  • @anna-mariakhalil5588
    @anna-mariakhalil5588 3 роки тому

    love this

  • @abdellahezahraoui4774
    @abdellahezahraoui4774 5 років тому

    Best video ever

  • @ahmedrefaat7001
    @ahmedrefaat7001 5 років тому

    Yr the best

  • @hiraishfaq675
    @hiraishfaq675 5 років тому

    great job

  • @asyed1497
    @asyed1497 6 років тому

    Phenomenal.

  • @muhamedshaban6087
    @muhamedshaban6087 5 років тому

    Thaaaaanks