Adrenergic Drugs Part 1 | Pharmacology | Dr Najeeb👨⚕️
Вставка
- Опубліковано 16 лип 2024
- #drnajeeb #pharmacology #medicines #adrenergic #drugs # adrenergicdrugs
Adrenergic Drugs Part 1 | Pharmacology | Dr Najeeb👨⚕️
Like this video? Sign up now on our website at www.DrNajeebLectures.com
to access 1000+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM UA-cam). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $59 ONLY!
Sign up now on our website at members.drnajeeblectures.com/...
---------------------------------------------------------------------------------------------------------------------------
Why sign up for premium membership? Here's why!
Membership Features for premium website members.
1. More than 1000+ Medical Lectures.
2. Basic Medical Sciences & Clinical Medicine.
3. Mobile-friendly interface with android and iOS apps.
4. English subtitles and new videos every week.
5. Download option for offline video playback.
6. Fanatic customer support and that's 24/7.
7. Fast video playback option to learn faster.
8. Trusted by over 2M+ students in 190 countries.
---------------------------------------------------------------------------------------------------------------------------
▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬
00:00:00 Introduction, Autonomic NS pharmacology, Subtypes
00:05:25 Neurophysiology of sympathetic and parasympathetic nervous system
00:10:30 How sympathetic nervous system activated? Function of hypothalamus and limbic system
00:16:20 Polyneuronal sympathetic descending pathway
00:19:16 Sympathetic outflow, Adrenergic and non-adrenergic receptors, acetylcholine, nor epinephrine
00:25:45 Recap
00:26:15 How nerve endings work? Neurotransmitter synthesis, storage and release
00:30:12 Synthesis of norepinephrine (Tyrosine, DOPA, Dopamine, Norepinephrine)
00:46:46 How norepinephrine release? Depolarization sensitive Calcium channel
00:55:15 Inhibitory function of Alpha 2 receptor
00:58:31 What happens to norepinephrine after its release?
01:07:16 Drugs effect on nerve endings of adrenergic transmission (Metyrosine, Reserpine, Guanethidine, Alpha methyl dopa)
01:29:50 Concept of agonist, antagonist, partial agonist, mixed agonist and antagonist
01:39:38 Adrenoceptor Blocker or antagonist (sympatholytic drugs)
Alpha blockers
Beta blockers
01:47:56 Recap
01:50:14 sympathomimetic Drugs and its classification
01:53:21 A) Direct acting sympathomimetic drugs
02:11:25 B) Indirect acting sympathomimetic drugs (cocaine, TCA)
02:22:40 Distribution of adrenergic receptors on different body tissues
02:43:23 Changes in body under the influence of adrenergic response
02:44:17 a) Changes in hairs
02:46:41 b) Changes in eyes (pupils, ciliary muscles, lens etc.)
03:01:12 c) Changes in GIT
---------------------------------------------------------------------------------------------------------------------------
Adrenergic Agonists are drugs that lead to stimulation of the adrenergic receptors. In doing so, adrenergic agonists generally simulate activation of certain aspects of the sympathetic nervous system and are thus also known as "sympathomimetics".
Mechanisms of Action
Overview
A diverse variety of sympathomimetics exist which operate using distinct mechanisms. In general, these compounds are divided into direct-acting, indirect-acting, or mixed-acting agonists depending on whether they directly activate adrenergic receptors or do so by indirect mechanisms
Direct-acting Agonists
Direct agonists physically bind the adrenergic receptor and simulate binding of an endogenous ligand. These compounds can be highly specific, activating only certain subtypes of receptors, or can be rather promiscuous.
Indirect-acting Agonists
Indirect agonists do not physically bind adrenergic receptors. Instead, these compounds indirectly lead to receptor activation through a variety of possible mechanisms which include promoting release of endogenously-stored norepinephrine from presynaptic terminals as well as inhibition of norepinephrine re-uptake and degradation from the synapse.
Mixed-acting Agonists
Mixed agonists simply refer to those compounds which display both direct and indirect mechanisms of actions. As such, these compounds directly bind adrenergic receptors but also promote the indirect mechanisms described above.
---------------------------------------------------------------------------------------------------------------------------
Join this channel to get access to perks:
Sign up now on our website at members.drnajeeblectures.com/...
/ @doctornajeeb
Follow us on Facebook :- / drnajeeb
Follow us on Instagram :- / drnajeeblectures
Finally I got the real teacher …. Who teachs for knowledge ✨……. not for the marks
The Greatest teacher of all time ever ❤❤❤
Thank you for all the love and support❤️
Proof Medicine has no barriers,.. Love from India♥️♥️
Thankyou sir to clear my consept very clear you are the best teacher of pharmacology. Thankyou so much sir love from India 🇮🇳
SIR,lots of love and prayers for good health for You.May God grant you more power to enlighten us all for ever❤From India🇮🇳
Thank you for your kind words❤️
best medical lecturer, always a pleasure to listen to
Sir aapke charno mein koti koti pranaam🙏🏻❤
Best video collection for medical students and doctors reviewing topics!!! Thank you Dr !
You are welcome❤
Thanks very much Dr najeeb..🍎 you motivate us more to love the professional
Glad to hear that❤ Stay blessed ❤
I haven't met any teacher who can make the concept clear like you👌
Love from🇧🇩.Always best wishes for you❤️
Glad to hear that❤ Stay blessed ❤
00000000000000000000⁰00⁰00⁰000⁰0⁰00
Sir Allah pak keep you in his bless ameen
Great personality Ma Sha Allah 💞 SIR
Thank you❤️ Keep supporting ❤️
Your lectures are very much helping me.
Thanks
JazakAllah
Glad to hear that❤️ Stay blessed ❤️
Thank you Sir
Your lactures are very much helping me ,thank you so much sir! Love from 🇮🇳
You are welcome ❤️ Keep supporting ❤️
Thank you Dr Najeeb🙏
You are welcome❤
Thank you sir.
You are just amazing
So nice of you🌹
You are doing marvelous job...its sadqa e jaaria..may Allah taala gives you immense reward for this..
Thank you so much 🙏
Only Words I can say Great Great Great!!!
Best teacher of my life Dr Najeeb Sir 🌼 Sir I haved clear my FMGE exam through your lecture thank you so much sir
Sir I have one question can I ask because sir you are great teacher I have only one question which always disturb me plz 🙏 sir can I ask ??
Thank you for explaining the concept in a very clear way sir❤
You are most welcome❤
He is simply slaying Pharma 🥵🥵
Beautifully explained 🙏
Thank you so much.
You are welcome dear❤
❤❤❤❤warmly waiting 😘
You're the Great Sir 💙
My allah reward you your dedication of hard job ❤
Thank you for your kind words❤
Tq so much sir great teaching ❤️❤️
Most welcome❤️ Keep supporting ❤️
Best teacher ever❤
Thank you❤
Clear concept👌
May God bless you, Dr.Najeeb
Thank you for your kind words❤
Sir you are the love of my life God bless you
Thank you for all the love and support❤ Keep supporting ❤
Your expectations is awesome sir♥️🥰☺️
Thank you for all the love and support❤ Keep supporting ❤
Love you Dr sahb ❤❤❤
Love you more dear❤
God Bless You
Thank you❤
amazing talent with diagrammatic expression i have a great respect and appreciation for you dr najjep.
It's my pleasure. Stay blessed ❤️
Love you sir❤All times favorite ❤
Love you more dear❤ Keep supporting ❤
Thank u very much sir❤️✨️
Most welcome❤ Keep supporting ❤
The ultramax pro god teacher's lecture is back. Thanks for this sir
You are welcome ❤️ Keep supporting ❤️
God bless u sir
Thank you❤ Keep supporting ❤
Amazing explainable ❤❤❤❤
Glad you liked it
Thank u sir😇
You are welcome❤
Thanks sir
Welcome❤
Excellent lecture sir❤❤❤
Thank you dear❤ Stay blessed ❤
I can't express my way about your method but I want to say that you are a best teacher for mine in the world in medical terms ❤
Thank you for your loving comment. Please keep supporting my work.
Truly defines how a great teacher look like... ❤❤❤
Thank you! ❤
Thanku very much sir,🙏👍
Most welcome
Great sir
Thank you❤
Excellent ❤❤ thank you sir
Most welcome❤
Dr sahb Hayati draz❤
Mindblowing… Kudos to the best teacher of the world. Thankyou Sir
You are most welcome❤
Wonderful lecture
Many thanks
Our teacher is the great
Thank you♥
Ja-Zak-Allah-u-khaira 💖💖💖
Thank you so much sir 💖
Most welcome
Sir you are best....
Thank you for your love and support. :)
Wah g ❤❤
❤❤
Superhero 🎉❤
Thank you so much sir 🎉🎉for helping us.. love from India 🇮🇳🇮🇳❤❤
Keep watching Keep supporting ❤❤
Even nurses are taking your lecture sir you are grooming us❤❤❤❤
Glad to hear that
Thanks sir for making things so simple i think i am blessed 🙏
It's my pleasure❤️ Stay blessed ❤️
May allah bless you sir,
Love from Bangldesh💗
Thank you for your kind words💗 Stay blessed 💗
Praye for Palestinians
Amazing !!
Thanks!! 🙏
Love u and best wishes sir love from core heart
Thank you for your love and support❤
What i am now is yours teaching.. i can’t thank you enough 🙏🙏🙏
Glad to hear that❤ Keep supporting ❤
With out subscription you provide us such important conceptual video.thank you sir❤
It's my pleasure❤
Sir these lectures are very helpful for our med schools❤❤
Love from India❤
Glad to hear that❤ Keep supporting❤
Great lecture ❤
Glad it was helpful!❤
❤......... Unlimited
Thank you so much ❤❤
Love Pak
Lots Of Luv from India Sir❤
Thank you❤
Thank you sir✨ sir plz upload anyi depressants
Will do soon. Happy learning ❤️
Sir I have one question about guanadrel drug...
That in your hypertension lecture you said that this drug go into follicle by Reuptake receptor of norepinephrine and the whole follicle filled with this guanadrel drug so norepinephrine is destroy by enzyme
But here you said different things
So I'm confused
All time fav❤️ heartfully tq sir
Most welcome ❤
I can understand one thing in between stimulation and inhibiting 😢 very confusing
Love ❤️ from India sir
Love you more dear ❤
Amazing teacher with amazing explanation methods
Glad you think so! Keep supporting 💞
How can i get notes of lectures
We don't provide notes instead we encourage students to make notes for themselves.
❤❤❤❤❤bd
🇧🇩❤️💚
❤❤
Thank you so much sir
Most welcome❤
thank u sir
Welcome