Synthesis of ATP (2018) Drew Berry and Franc Tétaz
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- Опубліковано 21 жов 2020
- From the wehi.tv "Respiration" (2021) animation collection, presenting the molecular mechanisms that power your cells and tissues, converting food and air into the flow of chemical energy that makes your body be alive.
"Synthesis of ATP" shows how the proton gradient across the mitochondrial membrane powers the ATP synthase enzyme to make ATP.
These animations bring to life the molecular engines inside mitochondria that generate ATP, the main source of chemically stored energy used throughout the body.
Music score and sound design written and recorded by multi-Grammy winning artist Franc Tetaz.
Created in collaboration between wehi.tv and HHMI BioInteractive.org for a new collection of free biomolecular animations designed for classroom science education, "Synthesis of ATP" combines the world's most advanced microscopy techniques, cryo-electron microscopy and molecular models to engage students with accurate inspiring biology. - Наука та технологія
The music Synched with the turning of the molecule is epic as hell.
It feels like doomsday is approaching and the mitochondrion being the bringer of it
Its like lightning in a bottle! 🌩
Incredible animations - keep them coming!
This one gave me shivers (good choice of music).
These animations always blow my mind, they really let me think about biology in ways that I never would have before and I think help my understanding beyond just watching stuff move around. Wonderful work!!
The 3-dimensional structures of each of those moving parts in these animation were figured out in labs by scientists who specialize in a field called structural biology. It’s really cool stuff, you should read up on it if this kind of stuff interests you.
@@xtldc Thank you, I will!
with every video, I am humbled and my mind is completely blown apart. I'm a visual learner and this series has been nothing more than a miracle. Thanks!!!
It not a miracle, a creator created .. very simple .
But it can be a miracle if it just came without a creator .m that would be crazy 😱
@@bestryfulhd2102 Then who created the creator? This only shifts the miracle up the chain of creation.
@@MrSupasonik nobody created the creator .
Creator is perfection of everything, independent and self sufficient that's why he eternal .
Matter is dependent so it can't be eternal cause it depends in someone to make it exists .
But we are going to die and we will see hell and paradise ..
@@bestryfulhd2102 That makes no sense whatsoever. According to you, humans need a creator, but the creator of humans does not need a creator.
This is an absolutely superb combination of art and science. An amazing skill and effort to represent something complex so clearly, eloquently, and most significantly, faithfully.
Thank you!
Thank you so much 😀
The Art comes from the creator. this is actually "just" good science, enabling us to see what is not visible (because of light, no'one's fault! :)
and we like to look at it, of course!
The animation, the explanation and the music...Biology is so fantastic, a masterpiece.
I cant imagine how life finds order amidst this seemingly uncontrollable chaos. Brilliant animation !
A lot of processes in biology (and chemistry) come down to 2 major factors - electric charge (opposites attract and like repels like) and physical size/shape (complimentary shapes fit together like a key in a keyhole - if a key is too big, it won’t fit in a keyhole - if a key is the wrong shape, it won’t fit in a keyhole).
It is one of the reasons why my belief in God strengthened while studying medicine.
"and consider the creation of the heavens and the earth, (and say): Our Lord! Thou createdst not this in vain. Glory be to Thee!"
And if you dare to study evolution itself instead of just medicine your belief would be gone, because of how little it takes to start accumulating complexity at an insane rate, in this systems, and you would be wondering why it took life so long to come up with intelligence.
@@odraz0101 i do understand that complexity is inevitable for sophostication and intelligent processes but one cannot stop but end up personifying this intelligence clearly because its different from other forms of random complex activity that is complex but not so interesting as life. And the fact that we differentiate life from other equally complex activity shows that we value it for its inherent beauty. Everything is complex and much of everything is described by mathematics and other sciences. But that doesnt make the underlying structure any less worthy of appreciation for their beauty. Complexity allows for intelligent and interesting phenomena. But the intelligence and interest is an attribute of the respective processes not of complexity.
Evolution leads to this, nature tries lots and lots of different possible solutions and some prove to be successful in better adapting the organism to its environment.
Our cells are really basically some complex machines made of many "simple" machines. It is really interesting to see, that not all action on a molecular level comes from chemical reactions, but from mechanics as we know it from our macro world as well. Great animation!
I have to say, ATP synthase does not look like a simple machine to me!!
@@RickyPollo Absolutely
g o d bible truth
Lies in the replies @@bretth4988
@@RickyPollo really? It's basically like a turbine and generator. The top part being the generator, and the bottom part being the turbine with the flow of protons making it spin.
Drew Berry, thank you! There are not many videos of this kind on the internet. That makes your works so valuable.
and he got 7 min on Ted xD
@@TOKRocK84 the guy clearly didn't waste his time making his presentation longer than necessary; he kept it simple.
Amazing! Crazy how the real life protein complex is rotating a hundred times a second, and there are trillions and trillions of these running in my body right now.
ABSOLUTELY FANTASTIC VIDEO.
You have brought something that looks boring on paper and shown it in it's life trough an amazing animation.
Thank you so much my test is in 2 days!!
The best video on ATP synthesis. This is beautifully done in terms of animation to audio with narration.
The best channel for animations on molecular biology ever!
I sthere another one of this sort?? :)
And the music... it's just awe inspiring.
Sorry to disagree, but the dreadful music ruins the whole presentation. What we are after in these types of uploads is information, clear and concise information, not some head- banging music which those who like such a thing can find plenty of here on UA-cam. All the best documentaries do not drown out the speech with awful drumming and incompatible 'music'.
With all respect, most people surely watch these amazing uploads to see the scientific content and learn about these natural wonders, they are not here to listen to this dreadful background 'noise' as I call it. This upload is ruined by the so called music and masks the narration. Just look at all the great documentaries like Planet Earth, Walking with Dinosaurs, etc., the sound on which is suitable for the subject matter. Anyone seeking this dreadful kind of background sound can find plenty on UA-cam without having to suffer it here. I hate to have to say it but it does seem to be far worse on US programmes.
@@JP-cy1lw You want all the scientific information but can't "behold!" any of it. And even this comment doesn't make sense to you as you seriously lack experience of life itself.
@@JP-cy1lw like it or not experience and entertainment has a big effect on how we learn things.
this makes these stuff stick to memory alot better than just leaving it bland.
also i dont see how the music on this one is bad. it deafen the speech at all. and the sync of the music to the rhythm of the molecular motor is pretty neat as well.
its mindset like that that makes science in itself hard for the general public to get into. why is there alot of wackjobs like flat earthers anti vaxers that reject science?
its cause of stuff like this that try to make it as clinically un fun as humanly possible.
I love how the rotation of that thing is in sync with the music.
These animations are visually stunning and very great learning tools, but lets give props to the amazing sound design too!
Simulation like this helps to look at biochemical processes from a different point of view. An incredibly efficient and beautiful synthesis process! Great animations!
Such incredible videos make me wonder how hard your team is working to make them. Im so greatful, thank you.
As soon as the video shows the inside of the mitochondrion, the quality settings went down to 240p. This video is high quality; that's what I love!
This kind of quality and precision changes the image that we have of microscopical events in our mind. As a biology undergraduate, i am very thankfull for the animation, it really helps us understand the biomolecular world better
Heaping glowing praise ! Top notch videos!
Fantastic! Such a powerful vibe.
Omfg. Please more! What is ur patreon account?! You are hereby ethically and academicly obligated to produce much more of this content.
Okay maybe the edict about ethical and moral obligation is a bit much, but I do align with the author’s intent 😊
these videos are made by the WEHI organization. sponsor them
Beautiful graphics! Kudos to the creator
Speechless! Thank you so much for your videos!
Brilliant! So many thanks for your hard work! It's easy to forget the dynamism when you're studying the pathways!
These animations are so cool. Biochemistry is absolutely bonkers. But there’s something so creepy about how these molecules look when animated
This music is nearly _exactly_ what I hear when I use DXM. My impression when I first started hearing it was that it was the chorus of countless microscopic entities (cells), the Song of Flourishing Life. That was seven years ago, and now, here I am, with exactly that playing out in this video before my very eyes. Incredible. What a profoundly, inexplicably beautiful world we live in.
Respect for the Brownian Motion that allows all of it to function . . .
I am awed! Thank you for making this type of quality video available!
I love the addition of music in this video
These videos are far better than the sci-fi movies.....🔥🔥🔥🔥...just awesome 👍🏻👍🏻👍🏻👍🏻👍🏻
beautiful work. I liked the audio too.
Cheguei aqui por dica do @oatila.
Obrigado Atila Iamarino. Por tudo.
absolutely love you for making this!
Amazing simulation
Drew Barry you absolute madman!
Mind bogging awesome animated video ,tonnes of knowledge in just 2 mintues
best animations I have ever seen
Excellent visualization!! Bravo 👏👏
its more beautifull than what i imagined .
beautiful animations. sadly youtube compression removes a lot of detail
I remember that back in school I had hadn't realized that ATP was part of the building blocks for DNA and RNA (just like GDP). With this in mind, plus the fact that ribosomes are mostly RNA, the RNA world hypothesis becomes almost obvious in hindsight -- RNA was the genes, the proteins and their means of energy exchange. It would be fascinating to discover that these tiny RNA creatures (if they could be called that) still live among us!
The "A" is also used by RNA and DNA, when connected to another large piece that's common to all 4 bases. Here, it has attached a chain if 3 phosphates (when charged) or 2 phosphates (when discharged).
The ”A” in ATP is the same ”A” code/building block (A, C, G and T/U) in nucleic acids, I get it. There's also CTP, GTP and UTP which were also (rarely) used as source of energy.
Looks like life as we know it had to rely on a Swiss knife kind of chemistry, self unfolding. Makes actually lots of sense.
Mind blown. Mezmirising and astonishing new learning.
What a lovely animation about our organism's analogy to turbine and charging up batteries keep working on this brilliant animations
I love these videos. I wonder what the time scale is.
it's in real time...
it takes months(5-6) to create a final ready to ship animation of 10 minute length at this detail
This is actually in real time :) fascinating!
Yea, Real-Time stuff, that'*s what makes it awesome! Try it as background videos of techno music... or any music... it's just ...cosmic!
@@dacsus It's not. ATP synthase rotates around ~100 per second in real cells.
I'm groovin with the ATP music
I cried.. Nice soundtrack. I love how she repeats the sentences as if they were lyrics, or mantras, to be repeated as an hymn.
"ATP drives biochemical activity inside your living cells, and is a key building block of DNA, and RNA"...
"ATP drives biochemical activity inside your living cells, and is a key building block of DNA, and RNA"...
"ATP drives biochemical activity inside your living cells, and is a key building block of DNA, and RNA".
Are you shitting me? THIS IS THE BEST FUCKING SHIT EVER!!! I've been watching physics videos all my life but this blew my mind away to the next dimension. MOOOORRRRRRRRRREEEEEEEEEEEE!!!!!!!!!!!!!
LOL! so true. It’s funny there are so many responses like this, WEHI knows they were blowing peoples minds.
the video is at ultimate level... Lively feeling
I love the artistic value of your videos!
Unbelievable that this is happening in our body's. It's a miracle.
The creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅
Amazing. Before I began taking many science courses for my undergrad, I had a friend who told me that the human body was a messy, makeshift thing, randomly pieced together in order to function at the most basic level. I knew he was wrong then and I am glad to now be able to explain to him why he is so very wrong.
Our body is SO WEIRD.
I LOVE IT.
What an awesome depiction! Thank you!
Beautiful. Magnificently beautiful.
Thank you very much!
Drew Berry work is awesome, so accurate and perfect.
I absolutely love this Vt...the music sets the grounds for wild Wondering and Pondering......remembering why i absolutely love this channel....Belfast Ireland 🇮🇪 ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤
This is amazing! Thank you.
These animations are a beautiful thing.
The work is amazing. Thank you
The motorized glory of it all. ❤️🔥
Best channel on YT
I wonder if we'll come up with a more efficient method of atp synthesis
I LOVE THIS. I WNAT THIS DONE WITH CHEMISTYR TESTBOOKS TOO. MAYBE AM INTERWCTIVE GAME ? LETTING YOUNG PEOPLE MIX CHEMICALS AND WATCH THIS WAY??? THE TEACHING POTENTIAL..... INSTEA DOF REAIDNGA ND INAGINING ALL THIS... I M SO SO HAPPY TO SE EIT . ITS ABOUT TIME!! WELL DONE!!
Your videos rise my reverence for live!
People really have hundreds of superpowers all working together so we don’t collapse on the ground
thank you mitochondria, thank you so so much.
This is very well done, thank you very much...
these are awe inspiring
UAU, essa simulação ficou muito incrivel
Subscribing because I'm gearing up for food biochemistry course next semester!
Beautiful and excellent work
mind blowing!!! Thank you!!
Question: Would the molecular/subatomic process be so fast, as to appear a blur in real-time? Like a high revving motor?
Yes, actually.
Thank you for this spectacular video
muchas gracias
I've rediscovered the meaning of having your mind blown... thank you 🤯
Incredible video, so fascinating
The animation is fantastic, but the commentary is so succinct and simple that I don't feel like I've learned much.
I think an hour long lecture could be made diving deep in this animation. How does the pump work? What are its parts? How do they interact? How is the pump made and how does it move to its intended spot? Why is there a difference in proton concentration?
More on Cell Respiration
ua-cam.com/play/PL04jnTG4d1nZuxdfgL85V27NPjFTl025Y.html
Free science education visit wehi.tv and biointeractive.org
The creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅
This is now my favorite video
Love these sm
This is amazing, more please🙏🙏🙏🙏
Remember, just a random clump of cells that just "formed together" one day, out of nowhere, for no reason..... I think seeing this lends credence to the fact that life is not coincidental but by design and the most intelligent of designs to ever exist, at least in our 'world'
"for no reason"
cuckoo, there are laws of nature actually
I wonder if one day we ll manage to engineer totally new machine made of such incredible nanomachine/mechanism. Evolution is so awesome.
Thank you!
i've done medical animations for surgeon training, the one that has most views on my channel (now way way out of date) is for "anorectal fistula" - the reference material for which was extremely gruesome and uncomfortable to watch, but i think the animation made it tolerable.
Thank you,good video
These amazing nano-machines.
The creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅
Drew Berry, more!!
Amazing video as always. Is there any way the music could be released as a stand-alone track?
Incredible.
Awesome!!
Mitochondria is the powerhouse of the cell!!
Wonderful!
Love this
Awesome 👌👌👌
Can we just simply fucking appreaciate the beauty of this animation and the skills it takes to make such thing rather than entering a fucking debate about God and creationism, please? Why do people need to bring God into every fucking things that they can't comprehend?
It's caveman brain, plain and simple.
I feel you, so deeply. I don't understand why they feel the need to bring up their religion - and specifically over science stuff like this one. All I can honestly say is that it's probably some evangelization agenda.
If you are so sure of yourself, explain how this process got started. Did you realize the creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅ Actually, God did to it. That's why evolutionists conveniently leave out the full facts.
@@SwanOnChips ATP occurs naturally in the universe. We don't know how, exactly, but they do. There are a bunch of proposed/hypothesized mechanisms on how they could form naturally, I suggest looking them up.
Love your videos!