PHARMACOLOGY; ROUTES OF DRUG ADMINISTRATION by Professor Fink
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- Опубліковано 16 чер 2014
- In this Video Lecture, Professor Fink identifies the major routes of administration of drugs and discusses the advantages and disadvantages of each. Reference is made to enteral routes, parenteral routes, intravenous (IV), intramuscular (IM), subcutaneous (SQ), Inhalation, Transdermal, Topical, elixir, syrup, emulsion, lozenge, troche & suppository.
Check-out professor fink's web-site or additional resources in Biology, Anatomy, Physiology & Pharmacology: www.professorfink.com
Down-loadable e-Books of the Lecture Outlines by Professor Fink can be purchased at: wlac.redshelf.com/
The “hard copy” of the Pharmacology Lecture Outline CAN BE purchased. Please e-mail Mr. Nilhson Zelaya, in charge of sales at the WLAC Bookstore. His e-mail is: ZelayaN@wlac.edu
He can tell you the cost.
I was lost in my pharmacology class until I started watch Dr. Fink's videos. He is phenomenal!
He is such a good teacher . Lucky students who could attend to his classes . I also love that he is clapping from time to time , it makes you pay more attention .
I just loved this lecture.....I am so thankful for this.I have just started my second semester of Pharm.D. and I am overwhelmed to have found this video.
Thank You for comments. You can see the "Playlist" for my Pharmacology Video Lectures at: ua-cam.com/users/professorfinkplaylists
What a brilliant lecture! So glad I didn't listen in class and studied here instead.
OMG I remember watching your videos on a&p for the follicular process and layers of different organs which helped me so much and now I'm watching your pharmacology videos, arriving here by complete coincidence! THANK YOU!!!
Great lecture. Very insightful. I've been curious to learn more about the relationship of a drug's PK/PD with its ROA and the reasons for those relationships and this was very helpful towards achieving that goal.
Your lecture was amazing, you break down pharmacology so well. Thank you!
So beautiful. His lecture is art with the hand gestures and the clarity
Thank you thank you thank you Professor, now I understand it much better even though I took these routes of administration two semesters ago!!
That was really interesting and clear teaching Sir! Thanks a lot!
Thank you Professor Fink , you are the best, I started with your Pharmacology Lectures...you explain so well and easy to understand, Now I have you as my Pharmacology Lecturer :), I also bought your notes to follow up the videos, Praise God...May the Good Lord bless you
Very well presented. Professor Fink makes pharmacology fun. Thank you professor.
Professor Fink you are an excellent teacher!! i enjoy your lectures very much please keep it up. I'm a medical student who's sending you love from Trinidad and Tobago :D
Professor, you are a grade saviour. Thank you !
This was so helpful! Thank you professor, I owe you one ! :)
Dr Fink has an amazing Link with Pharmacology.
Dr Fink your lectures turn me pink like a rose.
Your lectures increase my Zinc.
i can't even blink when see your lectures.
You really make me think,
Dr Fink i drink Milk and then click your link.
Your lectures are so interesting that time passes in a wink.
That is Dr Fink
Great content, very clear and precise. Thanks!
Omg i wish i had him for a lecture!!!!!
Aww! ,This professor make learning fun , I just found this channel and I enjoy it so much , thank you sir , 🥰love from Jamaica 🇯🇲🇯🇲🇯🇲.
I loveeeeee this professor!
kween410 and I love your smile :)
ikr hes just amazing
Like me
It took me one week to complete the tutorial. Was using it for research. I am happy. I did.
Thank you thank you for such a great lecture!!!!
i wonder such a good teacher i would ever get ,his teachings are cool man
What a great doctor and a great lecture !
best professor ever!!!
you are an amazing professor
Thanks very much professor ; I see your videos from Algeria and you re helping me a Lot
Amazing lecture!
You are a fabulous professor 🌸
u r simply amazing! Long live!
Thank you so much sir for your help...
It will be amazing if you provide the discussed notes in soft form as well....
what i can say for or to this prof he is more than elegant really thanks prof
Best explanation ever!!
Great video ....Thank you sir.
thank you very much. excellent lecture.
Thank you professor 👏👏
Thank you Professor
Thank you professor ...i am from india this was helpful
thanks professor this is my 3rd video to watch
Down-loadable e-Books of the Lecture Outlines by Professor Fink can be purchased at: wlac.redshelf.com/
The “hard copy” of the Pharmacology Lecture Outline CAN BE purchased. Please e-mail Mr. Nilhson Zelaya, in charge of sales at the WLAC Bookstore. His e-mail is: ZelayaN@wlac.edu
He can tell you the cost.
from Egypt
thanks doctor
You Welcome! Best Wishes -- professor fink
Wow thank you so much sir,i am an LVN student and i just started pharm;this helped me so much that i don't even need to read my book.lol.thank you
hey my name is kenyetta I am 17, and Im from Mississippi , but im currently studying to be an (CMA) Certified medical assistant in Memphis TN , right now in class we are going over pharmacology. your video lecture is very helpful to me I understand it very well with me being 17, with be being a minor in my classroom some things that are explain I don't really understand so I would have to go back and study it , or Google some of the words I write it down and I study it and I love your Video , I just now started to watch your video and I didn't stop , I love the way you teach . I just love everything about your Lecture , thanks .
Thank YOU, and Best Wishes for your Success!
OMG I cant believe you replied, :) but thanks so much !!!! I will keep watching your video's!!!! your the best !
Very nice sir
I've heard, at least in the case of methadone hcl that if vomiting occurs within 15 minutes of the dose then the patient must be monitored in several hours time and an administration of half of the amount of the original dose considered if withdrawal occurs. So does this mean that it takes only 15 minutes before the drug has passed into the duodenum and vomiting would no longer be an effective means for treating an overdose? I have also noticed the onset time for some benzodiazepines is around 10 minutes when given PO, though the peak levels in the blood aren't reached for another hour or two. But the fast onset seems to also agree with my thinking that vomiting may only be effective up to 15-20 minutes after administration of an overdose. Then again, it's a given that not all of the drug is going to be moved in to the duodenum at the same time, so some may still remain in the stomach after 20-30 minutes. And I wonder what effect drugs which affect gastric motility would have on this, as well as the onset time for some drugs. I guess it would depend on the PH of the drug and whether it's absorbed more readily in the stomach or duodenum.
great videos.do you have notes in power point form ?
Fantastic
This was helpful
Beautiful ❤️
Neither TB testing or allergy testing is done subcutaneously! Both of these tests are administered intradermally.
Here 7 years later
My ritalin is meant to be taken per os, and I do stick to oral with Concerta because it's a modified release, yet it works very well when insufflated, the onset of action comes from 1-2 hours all the way down to 15 minutes and since it's way more bioavailable that way I also can get the same effect with half the dose.
The only HUGE disadvantages are that:
-First of all I'm an addict and although I use my ritalin for legitimate reasons I can't honestly rationalise switching the route of administration to one that is known to have a greater risk of addiction and dependence.
-Secondly, Ritalin (Rilatine from Novartis in Belgium) pills are mostly talc and magnesium stearate, gelatin, starch, lactose and tricalcium phosphate. None of which can be good news for my lungs or even nasal mucus membrane.
-Also, because it is absorbed faster, doesn't get metabolised by the liver first (correct me if I'm wrong there I'm not sure about that), it's effect on dopamine level are also achieved faster which can lead to abnormally elevated levels of dopamine which can cause more side-effects including euphoria (perceived "high") and elevated blood pressure and heart rate.
-Finally, although the onset of action is shorter so is the duration of action which is also 1/4th to an half coming as low as one hour per dose.
So I wouldn't recommend insufflating ritalin if you're not already doing so.
I admit doing it on occasion when I forget to take my meds before school because I can't afford to lose time but still even after years of being treated with Ritalin, (mis)using it this way makes me feel almost too good for my own good so I avoid doing so no matter how pleasurable it is.
Which is a form of self-restraint that I wasn't born with but learned because of opioid addiction (now more than 3 years clean. Yes I sometimes have to push through with horrible pains but I rather do that than losing control of myself.)
And I have no clue why I'm giving you this anecdotal report of my experience… Gotta go back to procrastinating… Cya.
Great
excellent lecture thanks dr
Thank you! I understand better than reading in my native language
Hi
How are you
Which is the fastest method of drug absorption??
Professor please recommend for me which pharmacology book is the easiest and most understanding that i can use...or please tell me the book that you were using for teaching
Check-out professor fink's web-site for additional resources in Biology, Anatomy, Physiology & Pharmacology: www.professorfink.com
Down-loadable e-Books of the Lecture Outlines by Professor Fink can be purchased at: wlac.redshelf.com/
“Hard Copy” Lecture Outlines can be purchased from the WLAC Bookstore at: onlinestore.wlac.edu/fink.asp
Hello Professor,
I have a question regarding the sublingual route, can a patient take any drug sublingually if the bitter taste isn't the matter?
As it absorbs faster than other routes,if injections are not available at that time?
Or if i just make the powdered form of that medicine?
If you have time then please answer.
Thank you!
In fact, very few drugs can be absorbed well when taken sublingually.
@@professorfink Okay Professor, Thank you!
Me too....
Is the sublingual route more effective than buccal for nitroglycerin?
Buccal route appears to have a slight edge over sublingual. Here's a link to a clinical comparison: www.ncbi.nlm.nih.gov/pubmed/3117554
Efficacy of nitoglycerin will be decreased when given orally because if given orally it undergoes first pass metabolism so that almost 90% of the drug will be cleared.......so sublingual route is preferred for nitroglycerin
"Buccal" means within the "oral cavity", so absorption is similar to "sublingual" (under the tongue). "Oral" means SWALLOWED, which -- as you have correctly pointed-out -- will involve passage through the hepatic portal system and "first pass metabolism" through the Liver.
@@professorfink so buccal or transdermal patches is more likely to be used here?
does the sublingual route count as an enteral although it doesn't pass through the intestine ?
Yes, it counts as an "enteral route", which means through the intestinal tract (alimentary) canal). And like the other "enteral routes" Sublingual does not require aseptic technique.
Thank u !
What is the fastest route in absorption rate?!
Sublingual or inhalation?!
IF a patient is inhaling a bronchodilator (such as albuterol), it is acting topically on the airways & the action is immediate. IF a patient is taking a coronary vasodilator sublingually (such as nitroglycerin), it must be absorbed into the bloodstream and start to exert its action on the vascular smooth muscle, which will take a few minutes (to both dilate the coronary arteries -- and more importantly -- reduce Total Peripheral (Vascular) Resistance, which will decrease Cardiac Work Load and myocardial O2 consumption.
professorfink. Thank you professor
professorfink t
hello sir......
I wanna ask about effects of penicillin on E.coli.....
i mean they (E.coli) should also fail to form their cell wall in the presence of penicillin.......
Sir.....thank you so much for your reply........I hope you are generous enough that you would allow me to ask one more question........
We are studying virology now a days........I asked my teacher
"Since viruses can't generate ATP still their capsid contracts to inject their DNA,RNA into host cell....how is this possible...... I wasn't satisfied with his answer..... Can you please......thanks
My English is not that good......I beg your pardon in advance
see the Video Lecture: ua-cam.com/video/EDYfZ-DcNrw/v-deo.html
Sir.....thank you so much for your reply........I hope you are generous enough that you would allow me to ask one more question........
We are studying virology now a days........I asked my teacher
"Since viruses can't generate ATP still their capsid contracts to inject their DNA,RNA into host cell....how is this possible...... I wasn't satisfied with his answer..... Can you please......thanks
My English is not that good......I beg your pardon in advance
Excellent & sophisticated question. Here is a reference that addresses your question: www.mdpi.com/1999-4915/9/5/119/htm
professorfink
thank you so much Sir..........
Do i have lecture notes in pdf plz ?
Check-out professor fink's web-site for additional resources in Biology, Anatomy, Physiology & Pharmacology: www.professorfink.com
100% Down-loadable PDF e-Books of the Lecture Outlines by Professor Fink can be purchased at: wlac.redshelf.com/
i had paused the video ..i was thinking your hAnds couldn't get red rashes by slapping again and again ?i mean i had done twice my hAnds get red ...
It takes about 30 min for rectal route to show action.. Although it is used with unconsiousness(EMERGENCY) how come! Unconsious patient should wait for about half an hour!
In ANY Emergency, the IV (intravenous) Route is used. Rectal route CAN be used for non-emergencies in an unconscious patient.
@@professorfink sir how unconsiousness is not emergency
@@karimaehab8284 Here is an easy article about causes of unconsciousness & levels of unconsciousness: www.verywellhealth.com/what-is-unconscious-1298695