The Biology of Addiction

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  • Опубліковано 12 бер 2019
  • Each month The Brain & Behavior Research Foundation hosts a Meet the Scientist Webinar featuring a researcher discussing the latest findings related to mental illness. In March, 2019, the Foundation featured Dr. Eric J. Nestler of the Icahn School of Medicine at Mount Sinai.
    Description: Drugs of abuse target discrete collections of nerve cells-called circuits-in the brain that normally regulate responses to natural rewards in the environment, like food, sex, and social interactions. The areas of brain involved in these circuits are referred to as brain reward regions. Drugs corrupt these brain regions and circuits by activating them with abnormal power and persistence, actions that trigger adaptations at the molecular and cellular levels that are aimed to compensate for the drug-induced effects. These adaptations enable a drug to gradually and progressively take control over a vulnerable individual's life. During this Webinar, Dr. Nestler will describe these molecular, cellular, and circuit actions of drugs of abuse and how knowledge gained from this work can be used to develop more effective treatments of addiction.
    Learn more at www.bbrfoundation.org/event/b...
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КОМЕНТАРІ • 13

  • @eduardoduarte1968
    @eduardoduarte1968 3 роки тому +2

    Dr. Nestler is simply brilliant. These discoveries are exciting and mind-blowing. Thank you!

  • @pauldilley8974
    @pauldilley8974 2 роки тому +3

    Very interesting! I'm no biologist but if I understood correctly, what people get addicted to depends on their particular genetic makeup and the interact of the substance with their genes to produce epigenetic effects. Thus someone might be more affected by alcohol and not by opiates, whilst for another person it could be the reverse.

  • @panaceatherapeutics5148
    @panaceatherapeutics5148 5 років тому +4

    An excellent, precise and clearly articulated Webinar. The biopsychosocial model of addictive processes elucidated over the generally established and allopathically accepted medical model.

  • @JumpingJack6
    @JumpingJack6 Місяць тому

    4:30 Regardless of the genetic predisposition to become addicted, does it not require initial usage to trigger that addiction? Is that not a choice?

  • @VitaminJ7734
    @VitaminJ7734 4 роки тому +1

    This lecture is absolutely incredable - so I am wondering - would intentional inhibition of dopamine or lowering dopaminergic expression result in up regulation- thus' reducing dopamine seeking behavior in the long run?

  • @pacifiquebusiness
    @pacifiquebusiness 3 місяці тому

    🙏

  • @kolomalu100
    @kolomalu100 4 роки тому +1

    Can I please get some references I'm using some of this information in my essay

  • @annak29
    @annak29 Рік тому +1

    52:15 "age-related sensitivity"..."adolescent brain more susceptible to drug-induced changes" "prenatal brain and post-natal brain"
    54:04 "libertarian viewpoint" re: addictive drug legalization

  • @mysonstegman
    @mysonstegman 5 років тому +1

    Some say the addiction is but a symptom of a underlined problem and something that appeals to 12steps putting ones self back together cleaning out the closet righting wrongs (step9) forgive let go of guilt tools for healthy emotion handling being a part of fellowship an allow help from other and help others (12th) having a spiritual awareness

    • @tboyosborne
      @tboyosborne 17 днів тому

      12 steps works
      Also therapy
      Plus meditation
      Lotsa prayers

  • @bekindbehumankind8429
    @bekindbehumankind8429 3 роки тому +1

    How about forcefully induced drug and then becoming an addict like in babies born to drug addict mothers, and in drug induced in sexual violence, and drug induced captured victims...?

    • @stephanieguthrie5186
      @stephanieguthrie5186 11 місяців тому

      You sound sooooo ignorant.
      Babies aren't born addicted.
      They're born dependent.