A Scientist Huffed Gas In A Balloon. This Is What Happened To His Kidneys.

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  • Опубліковано 6 сер 2022
  • All references including the book are in this description, see below
    Patient MB portrayed by Abram Cutshall, Toast Scientist by Jake Rattan
    Special thanks Westminster Christian Academy
    Production Assistant Jake Rattan
    In-depth channel ‪@HemeReview‬
    Secret channel ‪@BigEmus‬
    This video has been dubbed using an artificial voice via aloud.area120.google.com to increase accessibility. You can change the audio track language in the Settings menu.
    IG me: / chubbyemus
    Tweet me: / chubbyemu
    Music by ‪@Lifeformed_‬ ► lifeformed.bandcamp.com
    Music by T4N3 ► / t4n3
    Medicine ► • Medicine
    These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
    References:
    Poisoning by arseniuretted hydrogen of hydrogen arsenide, its properties, sources, relations to scientific and industrial operations, symptoms, post-mortem appearances, treatment, and prevention. John Glaister. 1908. archive.org/details/poisoning...
    Tox and Hound Fellow Friday- Metal Hydries I. toxandhound.com/toxhound/ff-m...
    Sun HD, Ma L, Hu XC, Zhang TD. Treatment of acute promyelocytic leukemia by Ailing-1 therapy with use of syndrome differentiation of traditional Chinese medicine. Chin J Comb Trad Chin Med West Med 1992;12:170-171
    Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide. www.nejm.org/doi/full/10.1056...
    Acute on Chronic Arsenic Poisoning www.nejm.org/doi/full/10.1056...
    Mechanisms of arsenic: sites.dartmouth.edu/toxmetal/...
    Severe acute arsine poisoning treated by plasma exchange. www.tandfonline.com/doi/full/...
    Interaction of Arsine with Hemoglobin in Arsine-Induced Hemolysis. academic.oup.com/toxsci/artic...
    Arsine toxicity: Chemical and mechanistic implications www.tandfonline.com/doi/abs/1...
    Arsenate replacing phosphate - alternative life chemistries and ion. www.ncbi.nlm.nih.gov/pmc/arti...
    Arsenic Binding to Proteins. www.ncbi.nlm.nih.gov/pmc/arti...
    A biography of arsenic and medicine www.hkmj.org/system/files/hkm...
    Memorial Sloan Kettering Image by Kenneth C. Zirkel
  • Наука та технологія

КОМЕНТАРІ • 3,1 тис.

  • @chubbyemu
    @chubbyemu  Рік тому +9207

    WOOOOO yeah baby that's what i've been waiting for that's what it's all about

  • @adoptdontshop3911
    @adoptdontshop3911 Рік тому +8449

    A teacher huffing random gases he makes in front of students. Truly one of the moments of all time.

    • @Ebani
      @Ebani Рік тому +157

      Well yeah, it cannot not be one of the moments of all time 🤔 🤦‍♂️ 😅

    • @contingenceBoston
      @contingenceBoston Рік тому +474

      Undoubtedly one of the events in history

    • @OmegaLesPaul
      @OmegaLesPaul Рік тому +72

      he did it for the banter

    • @magnifeck4669
      @magnifeck4669 Рік тому +162

      Truly a moment that happened in time.

    • @zyaphyr
      @zyaphyr Рік тому

      Memento Mori fren

  • @mumtrz
    @mumtrz Рік тому +2305

    Man you have to REALLY keep an eye on this guy, previously he rubbed a whole tub of pain relief cream on his crotch and now inhaling 3 litres of poisonous gas?

    • @Candicedickinsonllc
      @Candicedickinsonllc Рік тому +269

      But he always comes back alive

    • @WooMaster777
      @WooMaster777 Рік тому +90

      Fans of this channel in the know. 😉🤣😂

    • @GeoNoob
      @GeoNoob Рік тому +62

      He is immortal though

    • @danishbutter1847
      @danishbutter1847 Рік тому +71

      @@Candicedickinsonllc he's Kenny, in Southpark he can't be killed

    • @chocolate198
      @chocolate198 Рік тому +9

      @@danishbutter1847 lmao 💀

  • @africanfartingfrog
    @africanfartingfrog Рік тому +1384

    Unfortunately for this guy, dialysis was still 125 years away. Makes you appreciate modern medicine

    • @Yeah_Nahhh
      @Yeah_Nahhh Рік тому +38

      2:20 “he struggled to call for 911” apparently there was phones and cars in the early 1800’s… 🙄
      3:09 blood tests didn’t exist then & anemia wasn’t even known about nor did watches & I doubt they used a sundial

    • @DedRucktheDuck
      @DedRucktheDuck Рік тому +107

      @@Yeah_Nahhh the story is dramatised but the case is from the 1800s look at 12:48

    • @codefreak8
      @codefreak8 Рік тому +94

      @@Yeah_Nahhh It's a dramatization based on a real event, but adapted into a situation that modern viewers would know what to expect if it happened to them.

    • @exantiuse497
      @exantiuse497 Рік тому +34

      @codefreak8 It has modern elements like calling 911 and blood tests, but then they just let him die as if modern treatments didn't exist. It's inconsistent; it should either have been written as it would've happened back in the day (e.g. instead of him calling 911 his assistant would've found him and taken him to the hospital on a horse carriage), or as it would happen today (he calls 911 and gets all the modern treatments and survives), not a weird mix of both

    • @BritishEngineer
      @BritishEngineer Рік тому

      @@exantiuse497 Mm

  • @secretsauceskateboarding4337
    @secretsauceskateboarding4337 Рік тому +511

    ChubbyEmu: “If you don’t need to put it in your lungs, don’t put it in your lungs.”
    Vapers: 😮

    • @therabbithat
      @therabbithat Рік тому +54

      Smokers: didn't react because they're already not alive

    • @The_Raven_1025
      @The_Raven_1025 Рік тому +51

      You mean this methamphetamine I got for Christmas isn't healthy?!

    • @lukethelegend9705
      @lukethelegend9705 Рік тому +24

      Smokers of tobacco, weed, crack, heroin, meth, etc: This sign won’t stop me because I can’t read

    • @LugaresYJuegosTM
      @LugaresYJuegosTM Рік тому +1

      ​​​@@lukethelegend9705 some vapers die from vaporized water overdose which is ridiculous I find vaping so gay 😂

    • @lukethelegend9705
      @lukethelegend9705 Рік тому +16

      @@LugaresYJuegosTM no need to bring homophobia into this

  • @Tommymad1
    @Tommymad1 Рік тому +1585

    "MB was a 31 year old man. As he fell he struggled to call his horse, who took him where he is now, the apothecary"

    • @WooMaster777
      @WooMaster777 Рік тому +30

      🤣😂🤣😂

    • @valkyriav
      @valkyriav Рік тому +380

      “The horse, when questioned about whether he knew what had happened to his rider, replied neigh.”

    • @TechneMakre
      @TechneMakre Рік тому +142

      @Aluzky while the horse is conditioned in its stable, MB is certainly not in a stable condition

    • @lleonard8854
      @lleonard8854 Рік тому +4

      😂

    • @seraphale
      @seraphale Рік тому +2

      Looool

  • @threebloodrubies2132
    @threebloodrubies2132 Рік тому +2193

    My favorite thing about the Wikipedia article for arsenic poisoning is that it lists "Drinking water without arsenic" as prevention

    • @spiritmatter1553
      @spiritmatter1553 Рік тому +152

      Yay Wikipedia, coming in clutch!

    • @tkat6442
      @tkat6442 Рік тому +310

      "Which type of bottled water would you prefer? With or without arsenic?"
      "I'll have without, please!"

    • @bruh-pj3kq
      @bruh-pj3kq Рік тому +90

      I mean… that’s factual

    • @lauriepenner350
      @lauriepenner350 Рік тому +48

      Citation needed

    • @Cairannx
      @Cairannx Рік тому +18

      @@tkat6442 I read that in Leslie Nielsen's voice in Airplane!

  • @labrabellart1380
    @labrabellart1380 Рік тому +204

    The fact that you explain why each thing is named the way it is, is so amazing. I'm autistic, and learning things the "normal" way by just taking in information and attributing names to it is really difficult for me. But learning the information behind those names helps me to understand it much better - not to mention the fact that I'll also be able to somewhat understand the meaning of OTHER names that use those same naming methods. It's extremely refreshing to see :D

    • @ilyouschka
      @ilyouschka Рік тому +2

      thats why…. nvm 🤦‍♀️

    • @ravenID429
      @ravenID429 7 місяців тому +4

      @@ilyouschka??

    • @DreamyyArt
      @DreamyyArt 5 місяців тому +2

      helll yeah no wonder i loved these
      im an aspie and i go "wait whazzat" and the video literally tells me about it for me and i dont have to google it immediately after, helps me understand what in the fuck is goin on

    • @criidawg
      @criidawg 2 місяці тому +2

      mfw i think im not autistic and then i see someone have the same struggles as me, and its because they are autstic: 😀
      (POSITIVE IM JUST RELATING LOL

    • @labrabellart1380
      @labrabellart1380 2 місяці тому +2

      @@criidawg Aah, that's relatable for sure! I spent a long time not really believing if I was autistic or not, but the sheer amount of times I came across autistic people who literally just described my habits as if they knew me, it kind of came clear.
      Kind of unsolicited advice here, sorry. But there's a test you can do online, did you know? It's called the Autism Quotient (AQ) test. If you're ever interested in finding out if you have more symptoms of autism, or even just ruling it out, that's a great place to start.

  • @goose5654
    @goose5654 Рік тому +665

    There is no way you paid the actor to mouth “WOOOO BABY! That’s what I’ve been waiting for, that’s what it’s all about!”

  • @ionymous6733
    @ionymous6733 Рік тому +1270

    if I ever present to the emergency room with some weird symptoms like this, my last words will be "Please, just contact Chubby Emu!" They'll be like, "Add delirium to his list of symptoms."

    • @manictiger
      @manictiger Рік тому +131

      Doc, you don't hear that music?

    • @poiuy2782
      @poiuy2782 Рік тому +5

      Hahhah

    • @JavaScrapper
      @JavaScrapper Рік тому +188

      “EMIA MEANING PRESENTS IN BLO-“
      *flatlines*

    • @gnarlynicholasreviews
      @gnarlynicholasreviews Рік тому +75

      @@JavaScrapper “Did the patient just say -emia meaning presence in blood…?”
      LMAO

    • @_Muser23
      @_Muser23 Рік тому +7

      This brought me the first laugh of the day 😂

  • @oliverwilson11
    @oliverwilson11 Рік тому +34

    Respect to this hero teacher who died trying to make chemistry entertaining and interesting for his students

    • @Mernom
      @Mernom Місяць тому

      You mean the teacher that set his students the example of huffing random lab chemicals?

    • @JosieJOK
      @JosieJOK 19 днів тому +2

      Ah, the age of scientific discovery, when scientists experimented on themselves! “Congratulations, you’ve discovered how to synthesize Arsine gas! Too bad you were your own lab rat!”

  • @WooShell
    @WooShell Рік тому +284

    Revisiting a centuries old case is some really nice and highly interesting change to the channel. Would appreciate if you did something like that every now and then 🙂

    • @Feyser1970
      @Feyser1970 Рік тому +3

      Cold cases

    • @Triadii
      @Triadii Рік тому +1

      I did not quite get whether he died from watching once, but I guess he died

    • @CoasterTeaFox
      @CoasterTeaFox 8 місяців тому

      Agreed

  • @priscilam.9808
    @priscilam.9808 Рік тому +2652

    My dad was born in 1945 in Brazil. He was treated for his severe asthma as a child with arsenic. He told the story that one day his stomach hurt so bad he was taken to the hospital and doctors figured he had arsenic poisoning. His family owned a chemical lab and he became a chemist later on. Another one of his treatments as a child for asthma was crushed up cockroaches made into a powder.

    • @bola5671
      @bola5671 Рік тому +329

      Well I'm curious if no one's asking. What were the crushed up roaches supposed to be a cure for?

    • @miscelaneasdealguem
      @miscelaneasdealguem Рік тому +110

      Que louco...

    • @Ebani
      @Ebani Рік тому +184

      They certainly weren't in it for the science

    • @screamingmimi90
      @screamingmimi90 Рік тому +17

      @@bola5671 I’d also like to know.

    • @OwlyFisher
      @OwlyFisher Рік тому +219

      @@bola5671 for asthma. reread the comment

  • @evilferris
    @evilferris Рік тому +2510

    Chemist here. Never, ever, drink or eat something that has been in laboratory glassware. Even if you personally and thoroughly washed it, some chemicals in trace amounts will do terrible things to your insides. This stunt at 0:56 makes me physically recoil. Besides, you shouldn’t be consuming food or drink anywhere near the inside of a laboratory.

    • @radicalbarrel2729
      @radicalbarrel2729 Рік тому +141

      Thanks chemist

    • @spindleblood
      @spindleblood Рік тому +378

      I hope they just opened those fresh out of the box and they'd never been used before. I keep telling myself that so I don't cringe like you did lol.

    • @TysonJensen
      @TysonJensen Рік тому

      We know this thanks to the noble sacrifice of many, many nineteenth century chemists who did just about every stupid thing possible with various reagents. Don’t make their sacrifice in vain! Avoid inhaling random substances from your lab!

    • @kalidwapur
      @kalidwapur Рік тому +41

      Yay and in biology our offices are often directly inside the lab...

    • @pluto8404
      @pluto8404 Рік тому +119

      Thank you for the insight. Found out my prescription meds were made in a lab, never taking those things again. Who knows how much damage those blood pressure meds made in lab equipment have done to me.

  • @neveragainlilhomie
    @neveragainlilhomie Рік тому +59

    these actors are top tier

  • @shawbros
    @shawbros Рік тому +76

    When I was a kid, I accidentally inhaled some acid fumes.
    It burned my sinuses, and really screwed up my sense of smell.
    I was beginning to think my smell would never recover, but gradually over a couple/few days it returned to normal.

  • @Diana3229
    @Diana3229 Рік тому +26

    I just found this channel and I am so so glad that someone out there is making videos that alert of the dangers of poisoning. I had been breathing in a small gas leak in my apartment for five months and not only did doctors not know what was going on at the time, but they also don’t know how to treat my symptoms. And this is in 2021-2022. Thankfully I am alive and recovering.
    The risk of poisonings in general are too high for us not to have more widespread information about them and the actual dangers it accompanies. Thank you thank you thank you for doing what you do!!!

    • @n646n
      @n646n 5 місяців тому +2

      Same happened to us, we'd been breathing in a natural gas (methane) leak for years due to improper installation of pipes. Luckily it isn't dangerous but the inspector smelled it immediately, somehow, despite nobody else ever smelling it.

  • @darkfent
    @darkfent Рік тому +2246

    Finally...I thought it would never came back. Afraid we would lose an episode just like that but thankfully it made a full recovery

    • @glenngriffon8032
      @glenngriffon8032 Рік тому +284

      A youtube video went to processing. This is what happend to its audio.

    • @MiTaReX
      @MiTaReX Рік тому +67

      Not just a full recovery, it is now better than before!

    • @dosmastrify
      @dosmastrify Рік тому +32

      It would never come back, he thought.

    • @JCSolis_Lit
      @JCSolis_Lit Рік тому +44

      A full recovery, unlike the patient of this video. ☠️

    • @barneyrubble4293
      @barneyrubble4293 Рік тому +3

      Definitely one of those of the world.

  • @Batmans_Pet_Goldfish
    @Batmans_Pet_Goldfish Рік тому +7

    Loved that you could tell what he was shouting by reading his lips due to how expressive the actor is.

  • @kenossa666
    @kenossa666 Рік тому +4

    I think that you telling a story which is really easy to understand and entertaining, while even informative-the actors are such a superb idea to add to this! I'm really glad I found your channel ♥

  • @MsGrilo12
    @MsGrilo12 Рік тому +3764

    I'm a chemist and I did not see that coming. Also, that's an excelent rule of thumb. If you don't need to get it in your lungs then don't (or at least try not to). Specially if you don't know exactly what it is. Excellent content, love your videos, I'am wating for next month already.

    • @gustavedelior3683
      @gustavedelior3683 Рік тому +79

      These things remind me of other incidents, such as the incident with the demon core or the incident with the professor who would put liquid nitrogen in his mouth and blow it out but one time ...he accidentally swallowed it. It would seem bravado and showmanship can be a detriment to science and the minds behind it

    • @timothyb.4928
      @timothyb.4928 Рік тому +31

      That's why i use needles for my H. Stay safe out there

    • @TheDragonLake
      @TheDragonLake Рік тому +49

      Also a chemist. I work with industrial hazmat. I just finished 2 weeks of computer safety training and spent 1 day in the lab so far. I dont remember the exact test but testing the hazmat fluid for cyanide, sulfates, or oxidizers involves mixing with sulfuric acid first. I've barely been in that lab but my ass whould be grass if anyone even thought about doing stuff like this. The dean at my undergrad school whould show us as freshmen the reaction of HCl + NaOH -> H2O + NaCl by drinking it. Really hope he stopped doing that by now for reasons like this. Reagents not made for consumption could be contaminated

    • @Mr.LaughingDuck
      @Mr.LaughingDuck Рік тому +46

      To be fair, why do you think today's labs are so highly regulated?
      Because some braggart did something predictably stupid, and was killed/maimed in a very disturbing manner.

    • @johnr797
      @johnr797 Рік тому +30

      @@Mr.LaughingDuck it's a good rule of thumb, if you see an oddly specific warning label on something, you *know* why it's there

  • @egodeathwish
    @egodeathwish Рік тому +68

    after five days in the hospital, MB was able to make a... contribution to science

  • @laurapeterson559
    @laurapeterson559 Рік тому +2

    These are the highlight of my month! I always think that I'm going to save it for a rainy day when I need to pick me up, but I never hold out for long. Please keep them coming!

  • @no.onecares
    @no.onecares Рік тому +2

    I started watching these videos like 2 years ago with my bf and I still find myself enjoying every story. Best way to distract myself from everything else, and also very informational. Thank you chubbyemu :)

  • @FramerTerminater
    @FramerTerminater Рік тому +715

    I work in a laboratory where we have large canisters of various pure gases such as hydrogen, argon, nitrogen, etc. In our safety training we received explicit warning not to use the gas to pitch our voices as there was a recent documented death of someone who passed out doing it, hit tiled floor face first, and died. Another victim of voice pitching...

    • @-grumpygold1155
      @-grumpygold1155 Рік тому +76

      Every time an intern walks in on their first day
      Intern: Oooh these gases seems fun 😏
      Supervisor: *sighs* Here we go again… ok, as per the newly added standard protocol, DO NOT inhale any of the gas canisters

    • @yoyo762
      @yoyo762 Рік тому +15

      Such professionalism.
      Higher education at work.
      Kind of like the warnings chain saws have about not touching the blades while they are in motion.
      I guess we need some Yogi Barra's about how the obvious is hard to see apparently.

    • @BeckBeckGo
      @BeckBeckGo Рік тому +52

      So when we were kids, my sister decided, on her birthday, to nonstop huff the helium tank my parents got for her balloons later that day while they were out getting her cake from the bakery.
      I did it too, once or twice, because who doesn’t want to sound like a cartoon? But she kept going. And going and going. And eventually she tried playing the fainting game with our friend and collapsed. And at first I though “ok, idiot daredevil is playing the fainting game” but she didn’t really get up.
      I was in lifeguard training at that time, so I checked her out, waited a few seconds, and then did CPR. She came around. I have no idea if she had just fainted or had suffered asphyxia from too much helium. (It’s an inert gas so it’s not toxic. But too much can suffocate you)
      Anyway, she was fine and my parents flipped their shit on both of us (unfair… but I wasn’t going to turn her in)
      Don’t do inhalants, kids.

    • @-grumpygold1155
      @-grumpygold1155 Рік тому

      @@BeckBeckGo its probably because she just had lesser o2 than its required to send to her brain, the helium takes up the o2 slot with each breath of the funny gas she took, good job on resuscitating her! she could had damaged her brain if no help came along immediately

    • @PrimericanIdol
      @PrimericanIdol Рік тому +5

      @@yoyo762 Gun safety is perfectly acceptable, and highly encouraged. Why not safety advice for everything else?

  • @fangbozhu7379
    @fangbozhu7379 Рік тому +593

    anyone ever notice the actors in the videos and just how well they're at presenting the state of mind of the kind of people who decide to literally snort up a balloon

  • @maryprantephd6736
    @maryprantephd6736 Рік тому +1

    I love your beautiful, rich color pallettes; you're not only artistically sophisticated, you're also technologically adept. Great episode. Thanks, Dr Bernard!🖼😊

  • @kellylynch975
    @kellylynch975 Рік тому +8

    Do more historical cases, please & thank you! I loved when you touched on the evolution of surgery sanitation.

  • @katanafourzeronine
    @katanafourzeronine Рік тому +404

    Not wanting to end up as a subject of a ChubbyEmu video is possibly the main reason why I've gotten my health act together in recent months.

    • @AB-ee5tb
      @AB-ee5tb Рік тому +80

      He said as he ate 100 multi vitamin gummies.
      These will make me healthy he thought, after all, they are vitamins.

    • @KonradTheWizzard
      @KonradTheWizzard Рік тому +38

      HK is a fan of this channel and devoted to a healthy life. Every day he goes to the local market to get fresh healthy organic food. But today while strolling through his favorite market section he breaks down with severe stomache pain. Horrified he watches the world around him turn dark while a cat is chasing a mouse between the market stalls... minutes later emergency services arrive and try to assess his state, but all he can mumble is "...emia means presence in blood...". HK is rushed to the ER where we are now...

    • @chaseshaw9130
      @chaseshaw9130 Рік тому +5

      same. his video on the homeless woman that ate all the cookies, and he proceeds to explain about insulin and refeeding syndrome, really helped me understand blood sugar and led me towards an almost-keto diet. it helps a lot now!

    • @fakename8956
      @fakename8956 Рік тому +7

      Me too, i quit snorting cocaine.
      Smoking crack cocaine contains less contaminants and is therefor much healthier.
      Thanks dr youtube :)

    • @erikb4407
      @erikb4407 Рік тому

      @@AB-ee5tb you got me audibly laughing like a psycho for a whole two minutes

  • @Findecommie
    @Findecommie Рік тому +919

    Would love to see more historical cases adapted, people did some crazy shit before anyone really understood biochemistry

    • @asandax6
      @asandax6 Рік тому +20

      Like the Curies.

    • @dr.altoclef9255
      @dr.altoclef9255 Рік тому +26

      In my college physics course we covered nuclear physics and they showed us an old ‘Revigator’…where you would put water in to make radium water. Because “this is so cool so it probably does great stuff if you drink it”.

    • @tylern6420
      @tylern6420 Рік тому +8

      @@dr.altoclef9255 bro really thought drinking radiation would turn you into luffy 💀

    • @dr.altoclef9255
      @dr.altoclef9255 Рік тому +15

      @@tylern6420 Pretty much. Like “well we discovered this new thing so…it probably fixes all our problems and let’s try it. Don’t bother testing it first, it’s fine I’m sure.”

    • @tylern6420
      @tylern6420 Рік тому

      @@dr.altoclef9255 tho tbh if it did actually turn me into rubber i would drink it

  • @stevepotts7024
    @stevepotts7024 Рік тому

    I am glued to your webinars! Very insightful. The mug was stylin'. Thank you Dr. Bernard! P.S. I mention your website other people all the time...

  • @kellyford8832
    @kellyford8832 Рік тому

    thank you bro, and best of wellness to you and all who you know and their friends and family too

  • @maximvf
    @maximvf Рік тому +140

    The first successful dialysis was performed in 1943. No chance for poor guy back in time.

  • @DrJohnWatson8
    @DrJohnWatson8 Рік тому +100

    “If you don’t have to put it in your lungs, don’t put it in your lungs”
    Words of wisdom

    • @twixxtro
      @twixxtro Рік тому

      I don't have to put air in my lungs only if i want to survive

    • @marks6663
      @marks6663 Рік тому +1

      That applies equally well to anuses, too.

    • @CloudyStxr_
      @CloudyStxr_ Рік тому

      ​@@marks6663 huh? xD

    • @FatalShotGG
      @FatalShotGG Рік тому +1

      *reads this while smoking weed*

  • @iananderson8363
    @iananderson8363 Рік тому

    I love the way the music changes, you have a great production value Dr!

  • @DelfinaKS
    @DelfinaKS 2 місяці тому

    Modern medicine is wonderful but it has evolved to a great extent due to the meticulous documents kept over centuries. It is amazing that back then this case was recorded in such detail. You are doing a wonderful job to document current understanding in video format but with proper references in the description. It is people like you who help make progress in medicine. Keep up the good work!

  • @momothebug
    @momothebug Рік тому +374

    I really appreciate the information about arsenic's use in Chinese traditional medicine and how that lead to some modern cancer treatments. It was also cool to hear you use a couple of Chinese names, it's neat to hear it pronounced properly and to hear you use a little bit of Chinese, thanks as always Dr Bernard!

    • @Objectified
      @Objectified Рік тому +4

      Arsenic use in the treatment of a variety of illnesses evolved independently in a number of areas. Arsenic derivations for blood illnesses and cancers were in use in the U.S. well before the advent of Arsenic trioxide for APL. Arsenic trioxide itself was in use for other purposes when the Chinese study on APL was released.

    • @momothebug
      @momothebug Рік тому +5

      @@Objectified thank you for the information :) I like learning about these things because all I knew prior to this was "arsenic is a dangerous, poisonous substance" and didn't know it was used in medicine, traditional or western. Very interesting.
      I suppose there are a lot of "dangerous" things that are used in medicine, from opium and amphetamines to viper venom and mercury. Arsenic is just one I hadn't heard anything about before.

    • @vinslungur
      @vinslungur Рік тому +4

      Chinese sounds so cool to me. Tones are so important to the meaning of chinese words

  • @windCR
    @windCR Рік тому +458

    This case made me even more grateful of medical treatments we have compared to even 30 years ago, thank you chubbyemu for bringing this up!

    • @ROGER2095
      @ROGER2095 Рік тому +5

      No better time to be alive than now.

    • @ousarlxsfjsbvbg8588
      @ousarlxsfjsbvbg8588 Рік тому +8

      @@ROGER2095 In comparison to the past, of course, but I’d rather have been born 10000 years in the future.

    • @LordCoeCoe
      @LordCoeCoe Рік тому +6

      @@ousarlxsfjsbvbg8588 What if humanity has been enslaved by aliens in that time?

    • @ROGER2095
      @ROGER2095 Рік тому +11

      @@ousarlxsfjsbvbg8588 10,000 years - That's way beyond my imagination. I have an encyclopedia from the 50's that says by the 1980's, robots will be doing almost all the work, and humans will be living a life of leisure. Still waiting . . . .

    • @ShadeSlayer1911
      @ShadeSlayer1911 Рік тому +3

      @@ousarlxsfjsbvbg8588 but we have no idea if the future is good or not. I'm usually the optimist who believes that humanity will always find a way to kve forward In an overall positive way. But I can't pretend to know that 10k years in the future will definitely be a good time.

  • @stephaniemixon6386
    @stephaniemixon6386 Рік тому

    Love your channel…Perfect the way it is. I learn so much.

  • @rohitchaoji
    @rohitchaoji Рік тому +2

    These actors are great, they give a nice and hilarious performance for subjects so serious

  • @ryanlee5593
    @ryanlee5593 Рік тому +396

    As a undergrad phosphorous chemist, we had a similar incident involving diphenylphosphene (the phosphorous depiction 6:37, but with two of the H's replaced with phenyl rings). This sample came in a broken ampule in our lab and unexpectedly blew up in a lab member's face (he's doing fine don't worry). There is a lone pair on the phosphorous that can easily be oxidized and releases a LOT of energy in doing so. In case anybody was wondering about the spontaneous body combustion that was described.

    • @akshinbarathi8914
      @akshinbarathi8914 Рік тому +4

      phosphot properties are used for weight loss supplements lol, like 2,4 dnp

    • @zath3153
      @zath3153 Рік тому +17

      Holy shit! I totally missed that the first time around. It can cause spontaneous human combustion when IN the body!? That's terrifying.

    • @pierrecurie
      @pierrecurie Рік тому +12

      @@zath3153 That claim is highly sus, and I can't find a source for it. Phosphine is highly flammable, but causing spontaneous human combustion is very unlikely.

    • @AhmetOzdemir-om3bj
      @AhmetOzdemir-om3bj Рік тому +3

      @@akshinbarathi8914 DNP does not have a phosphorus atom.

    • @akshinbarathi8914
      @akshinbarathi8914 Рік тому

      @@AhmetOzdemir-om3bj yeah my miatske

  • @DoctorAzmain
    @DoctorAzmain Рік тому +209

    Pro tip from a doctor: PLEASE don't inhale random gases - nitrous, your own farts, ESPECIALLY not arsine. Like, just why would you? How would you explain it in the ER?

    • @Eibarwoman
      @Eibarwoman Рік тому +61

      Don't be an arse, avoid arsine gas!

    • @DoctorAzmain
      @DoctorAzmain Рік тому +23

      @@Eibarwoman haha this should be a tagline in chemistry labs across the world 😂

    • @MLG_Kitten
      @MLG_Kitten Рік тому +22

      Well. In my city we have a lake full of arsenic, so some summers we have to boil our water.
      If you're curious, it's the Great Slave Lake (guess how many times I've been cancelled over that) I live in Yellowknife, somewhere north on the lake lol.

    • @mightbetoad6786
      @mightbetoad6786 Рік тому +20

      farts???

    • @Finkelfunk
      @Finkelfunk Рік тому

      If you actually know half the shit an ER nurse has seen just this morning I doubt that even the most embarrassing explanation is gonna raise an eyebrow.
      ER nurses and doctors have seen it ALL.

  • @Timok67
    @Timok67 Рік тому

    This channel gives me a greater appreciation for the complexity of the human body that we take for granted on a daily basis.

  • @Mina-gs8tq
    @Mina-gs8tq Рік тому

    Thank you for the best comments section I've seen in a while!

  • @Fiverr7890
    @Fiverr7890 Рік тому +45

    I love the way he says "Take care of yourself, be well." It's euphoric honestly.

  • @AngelWish3
    @AngelWish3 Рік тому +133

    I hope that the real patient can look down from wherever he is and appreciate that his death helped educate us on how to treat this type of poisoning. His sacrifice may have not been on purpose, but such accidents are part of why we learned how to help people. I hope he can take pride in that fact, wherever he is.

  • @AlkisGD
    @AlkisGD Рік тому +3

    “People would suffer illness and be found not alive days later, just like M.B.”
    What a way to deliver the devastating news! 😭

  • @Gratefullydead2k2
    @Gratefullydead2k2 Рік тому

    I love your videos so much. It helps me not think of all my medical stuff going on oddly enough

  • @chesthoIe
    @chesthoIe Рік тому +42

    If you turn on subtitles, you get at 8:14 "It was used as a pesticide, and the Romans knew it as the King of Poisons, it was a poison of Kings because it was an untraceable way to get rid of someone. English sources say that the French at one point knew arsenic as the Powder of Inheritance, where it was used in untraceable deaths of the elderly. "I totally have no idea what happened to them, they just got sick from the food!" would be brought up to insurers, and wealth and an estate would be passed on."

    • @JFDSmit-rm6tw
      @JFDSmit-rm6tw Рік тому

      @@MadeOfConfusion play it at the slowest setting.

  • @andyb1653
    @andyb1653 Рік тому +30

    "The biggest difference between poison and medicine, is dosage"
    -My Endocrinologist

  • @dn5662
    @dn5662 Рік тому

    Watched all your videos. The more you know the more you realize you're not in control of your body in a molecular level. Disrupt that balance, bad thing can occur. Just like the ecosystem, the air we breathe, combustion engine, to name a few.
    Thank you Bernard, for your knowledge and the way you deliver them.

  • @DRZWhisperer
    @DRZWhisperer Рік тому +1

    A good video as always. I really enjoy the history lesson along with it. Well done.

  • @marukomu_7105
    @marukomu_7105 Рік тому +16

    1:50 the meme lord never fails to put Easter eggs in his videos

  • @lisaschuster686
    @lisaschuster686 Рік тому +76

    Scientists had very short life spans when these compounds were being discovered. Chemists always recorded taste, for example. If you don’t need to put it on your tongue...

    • @BlurbFish
      @BlurbFish Рік тому +14

      Chemists of old had some workplace practices that today seem insane. They would mouth-pipette, haphazardly use solvents such as benzene, chloroform, carbon tetrachloride and carbon disulfide, and they'd work in areas without adequate ventilation. Smoking in the lab wasn't entirely uncommon, either.

  • @melissahowtonpoole.1120
    @melissahowtonpoole.1120 Рік тому

    I've watched many of your videos and I enjoy learning the science from them. I wish you could do more than one a month, but I understand you have life besides the videos. Thank you.

  • @janeosborne165
    @janeosborne165 Рік тому

    Good one ~ I had absolutely no clue about what was causing MB's problems.

  • @if860
    @if860 Рік тому +174

    Ah, the "good old days" where sulfuric acid was always contaminated with arsenic, mercury, lead, sometimes selenium, thallium, and tellurium, cause this elements frequently are present in pyrites and sulfide ores, and also in lead used for lining of the apparatuses for H2SO4 production. Even nowadays when we have reagents available that are so pure that contaminants are given in ppm you can still buy special grade of zinc described as "free of arsenic", meant to be used in demonstration of Marsh's test, since marsh test is so sensitive for As and Sb.

    • @evelynu3550
      @evelynu3550 Рік тому +17

      Ah, thallium. Nothing gets rid of unwanted (and wanted) hair better.

    • @chemistryofquestionablequa6252
      @chemistryofquestionablequa6252 Рік тому +11

      @@evelynu3550 gets rid of life too...

    • @if860
      @if860 Рік тому +6

      @@chemistryofquestionablequa6252 GETS RID OF UNWANTED PERSONS :D

  • @drhandcraft
    @drhandcraft Рік тому +323

    Chubby, this is so cool!
    I actually worked in the basic research lab right across Pier Paolo Pandolfi, which is referenced in the Sloan Kettering paper. This is soo cool!
    My research project actually entailed using ATO (Arsenic Trioxide, in conjunction with All Trans-retinoic Acid (vitamin A) to treat not only APL but also breast and pancreatic cancers.
    This is so neat! I learned a lot from this video!!

    • @noob19087
      @noob19087 Рік тому +4

      You seem like someone I could ask. Why isn't the arsenic trioxide toxic? Is it just a case of "the dose makes the poison"?

    • @coffeetoffee0x019
      @coffeetoffee0x019 Рік тому +7

      @@noob19087 could also similar to why sodium chloride doesn't explode or get insanely poisonous, like sodium and chlorine respectively

    • @krisreddish3066
      @krisreddish3066 Рік тому +12

      @@noob19087 I think you are right, or the selective dose kills the selective cancer cells more than it kills other cells in this case. Like how many chemotherapy class drug works.

    • @chrisnotyou
      @chrisnotyou Рік тому +1

      Uh..
      Spoilers. Gah!

    • @solarmoth4628
      @solarmoth4628 Рік тому +8

      It’s wild that the comment I saw right after was someone describing how they had been treated with this exact regiment. It must feel cool to see your research in action.

  • @astarryeyedgirl
    @astarryeyedgirl Рік тому

    I am HERE for the actor you chose! Good one!

  • @tonyquark493
    @tonyquark493 Рік тому

    As usual, your videos are informative, entertaining, and speak to humanity as a whole. Great job and great info!! Wow, that was a lot of information I never knew, and I thought I knew a lot :)

  • @localmenace3043
    @localmenace3043 Рік тому +45

    Man, I always hate it when the patient dies. The fact that this case happened almost 200 years ago - and that it can still happen today? Wild.

  • @Shikujiru
    @Shikujiru Рік тому +454

    Hah! Glad you got the audio fixed! Like I said last time: As always, informative and thought-provoking. Your manner of presenting these problems is enough to make me think fondly back on the chemistry and biology classes I took in high school and remember my love of science. These videos help me understand why I should and shouldn't worry about my health and move me toward making better, more-informed decisions when I do feel ill.

    • @brambl3014
      @brambl3014 Рік тому +9

      I did see when this video was uploaded the deleted quickly few days ago

    • @faithdorey5919
      @faithdorey5919 Рік тому +5

      @@brambl3014 yah! I thought that was because UA-cam didn't like it and it got demonitised or something

    • @thedeviouspanda
      @thedeviouspanda Рік тому +2

      Yes, I tried to play it on my way home and I thought it was my Bluetooth acting up.

    • @maciejp7829
      @maciejp7829 Рік тому +2

      didnt notice any audio issues when I watched it few days ago. Probably because I watch at 1,5 speed.

    • @artwithsoli5450
      @artwithsoli5450 Рік тому +1

      @@brambl3014 I saw it for a split second and then when I came back it was gone hah, I thought I was hallucinating or something

  • @CircsC
    @CircsC Рік тому

    This actor brings wonderful chaotic energy to the role

  • @ATIbbettMedia
    @ATIbbettMedia Рік тому +6

    I was treated for APML with arsenic trioxide, been in complete remission for 3 years!
    Great video Chubbyemu

    • @dshe8637
      @dshe8637 Рік тому +2

      That's so good x

  • @hemaurr
    @hemaurr Рік тому +13

    YES I WASN'T ABLE TO SEE IT THE FIRST TIME ITS FINALLY UP

  • @ItsJustJessOkay
    @ItsJustJessOkay Рік тому +14

    1:42 Scientist mouths the words!! Woooo baby! That's what I've been waiting for, that's what it's all about!!

  • @Viddough
    @Viddough Рік тому

    This is the most fascinating channel on UA-cam

  • @sandipanchatterjee5017
    @sandipanchatterjee5017 Рік тому

    His “Be well” can make everyone becoming well

  • @drivers99
    @drivers99 Рік тому +27

    “This video is ready to be uploaded. I won’t have to fix and re-upload it,” he thought.

    • @tkat6442
      @tkat6442 Рік тому +4

      But he made a "FULL RECOVERY"!!

  • @joshuamlnarik5942
    @joshuamlnarik5942 Рік тому +124

    The quality of your content is easily putting you at the absolute forefront of a much much needed niche. And your pragmatic organization of the information and the way you relay it in concise language simple enough for any laypeople to understand. Somebody smelt an ingot into a chubby 24K golden emu award. You're doing a service to the world 🌟

  • @angrypastabrewing
    @angrypastabrewing Рік тому +4

    As a Chemist, he should at least test the metal shavings first for contaminants if he still insist on inhaling hydrogen gas

  • @themightyai-5302
    @themightyai-5302 Рік тому

    I just love documentation. Good documentation makes everything better.

  • @SubaruLove
    @SubaruLove Рік тому +45

    I worked in a pharmacy cleanroom. I accidentally shattered a glass ampule of arsenic trioxide while preparing a dose. I immediately thought I was going to die, until I saw the patient was getting 10ml of it. Sharp glass and poisons are a scary combination.

  • @82dorrin
    @82dorrin Рік тому +22

    " ...he struggled to call 911."
    Well, yeah. Telephones weren't invented yet. Neither was 911.

    • @Kyanzes
      @Kyanzes Рік тому

      Yeah, sounded out of place.

    • @dr.altoclef9255
      @dr.altoclef9255 Рік тому +1

      He probably called for a servant to get his horse or something.

  • @minakimiz
    @minakimiz Рік тому +8

    hi chubby, i love that you speak and pronounce chinese correctly and refer to its medical history and practice. it feels so good to see eastern asian history represented in videos !

  • @darrelllancaster9554
    @darrelllancaster9554 Рік тому

    Kudos to your actors. As well as the excellent content of the videos.

  • @pegasBaO23
    @pegasBaO23 Рік тому +17

    I would say the chemist was dumb for inhaling whatever he made, but in the 1800s chemists would taste, smell and even inhale their chemical discoveries so they can record it in their journal

  • @marcelomagofke1743
    @marcelomagofke1743 Рік тому +31

    I love your sound design. The music you use for exposition during the symptoms before and during the hospital visit is fantastic at building tension! Your analysis and graphics used, combined with the real-life dramatizations really play together to create a professionally made video that deserves all the praise. Can't wait for the next Heme Review

  • @AdmiringObserverR
    @AdmiringObserverR Рік тому +1

    I love your content Dr. 🧡 wonderful job as always.
    I can't help but think about vaping trends with that warning of keeping things out of your lungs.

  • @beatiger9361
    @beatiger9361 Рік тому

    I like the way you tell the story. With excellent actors.

  • @Xclub40X
    @Xclub40X Рік тому +24

    0:49 MB WAS a scientist.
    *now he is no more*
    *For what he thought was H2O*
    *was H2SO4*

  • @00kidney
    @00kidney Рік тому +113

    Thank you for another amazing video! Learning about how they treated patients back then makes me really grateful for all the incredible advancements medical science made and that can help us today.

    • @TheMessiahOfThe99Percent
      @TheMessiahOfThe99Percent Рік тому

      WWII, Post-War and the Great Society
      a) Why did the American economy boom during WWII?
      b) How did government initiatives stabilise and support the economy in WWII?
      c) What populations economically benefited from the war?
      d) How did the GI Bill support the American Dream for WASP men?
      e) How did suburbs develop after the war?
      f) How is the Great Society an example of progressivism?
      g) What is the link between the Great Society and the Vietnam War?
      The Sickened Economy, Reaganomics and the Obama Era
      a) What is stagflation?
      b) Why did the USA enter a period of stagflation in the 1970s?
      c) What is OPEC? How did their embargo impact the American economy?
      d) How did Nixon, Ford and Carter attempt to address the economic issues?
      e) What is supply-side economics?
      f) What is a deficit? Why did Reaganomics create a high deficit?
      g) Where did Reagan focus federal spending during his administrations?
      h) What caused the economic crisis of 2007-08?
      i) How did the government respond?
      j) What is the Affordable Care Act?
      k) Why were Americans so divided over the Affordable Care Act?
      Following are some debate points to consider for ‘The Business of American Business’ as a whole These must be DEBATE points - questions where there are at least 2 potentially opposite perspectives. These are not ‘research questions’.
      Reflect on the key themes that have been introduced and revisited throughout this unit:
      The Growth of Capitalism The Establishment of Big Business
      Class division Personal wealth

    • @ryandoyle3413
      @ryandoyle3413 Рік тому

      I recommend Sawbones, a podcast about just that! A doctor and her husband going over old times cures, modern wellness trends, and current events

  • @leegoddard2618
    @leegoddard2618 Рік тому

    Suddenly recently you been popping in my feed. Glad you pOpped Up. 😁👍

  • @etanz
    @etanz Рік тому

    the music getting off as hes getting sicker is a good touch :)

  • @barretprivateer8768
    @barretprivateer8768 Рік тому +25

    That was like a speedrun to kill your kidneys, the reaction was almost instant after he inhaled it. Someone let Tomatoanus know.

  • @verukasault9065
    @verukasault9065 Рік тому +30

    Fascinating case! Thank you, Dr. Bernard. I like the mix of discussing a historical case and today's technology. RIP to MB.

  • @boughtbythecross
    @boughtbythecross Рік тому +1

    I was just recently diagnosed with chronic t cell large granular lymphocytic leukemia. When going through the testing I had already decided come what may I would not go through treatments. Thankfully this is not one that requires chemo. I cannot imagine purposely putting things into your body to heal you that would normally kill you! That's crazy how that works...

  • @maxblanchard5258
    @maxblanchard5258 Рік тому +1

    It always hits different when they share your name, and then they die at the end

  • @cbmx1x1
    @cbmx1x1 Рік тому +17

    Seriously, I wonder how many kids have developed a love of science, chemistry, and medicine as a result of these videos. Excellent work!

  • @KomradZX1989
    @KomradZX1989 Рік тому +11

    The music you play when people take drugs or whatever is so off putting yet perfect. Every time I hear it play in your videos I think “oooh, things are gonna get good now!” I love it!

  • @lowkeyyogitremendous
    @lowkeyyogitremendous Рік тому

    This is amazing, I really appreciate this

  • @marikamariamagdalenam
    @marikamariamagdalenam Рік тому

    Love the video, especially the guy who portraits the teacher, so enthusiastic 😛🤯

  • @brandonrhys21
    @brandonrhys21 Рік тому +48

    Thanks for bringing us great, medical-scientific content monthly.

  • @argoth83
    @argoth83 Рік тому +8

    These videos never cease to be incredibly interesting. Easily one of the best channels on UA-cam, and important.

  • @henriettewisti7728
    @henriettewisti7728 Рік тому +1

    I just love how excited this guy is about inflating a balloon

  • @TwentyNineJP
    @TwentyNineJP Рік тому

    Cutshall is devouring the scenery and I love it

  • @paramchaudhary3583
    @paramchaudhary3583 Рік тому +8

    4:00 I love that Charlie screaming WOOOOOO YEA BABY is still a meme

    • @Styrac
      @Styrac Рік тому

      He also does it at 1:50, lmao

  • @firesandflowers
    @firesandflowers Рік тому +142

    I had APL & had to have arsenic trioxode (intravenously) & All-Trans Retinoic Acid (ATRA) in 2015. The arsenic trioxide actually wasn't so bad. But the ATRA pills (which technically is just a vitamin A derivative in very high doses) gave me *debilitating* headaches (like, vomiting from pain, back in the hospital kind of headaches). It was awful. Most people don't have that side effect though aparently, so I guess I was just unlucky.

  • @michaelhicks8603
    @michaelhicks8603 Рік тому

    Thankyou! Another fantastic video. It was especially good that you took the time to explain why these chemicals (despite their toxicity) should not be feared but respected due to their critically important uses. As an inquisitive amateur chemist, I find public perception of chemistry to be poor, and plagued by dogmatic rhetoric and intense ignorance. I hope that more professionals and creatives can slowly change the perceptions, especially with content just like this!

  • @j.d.4697
    @j.d.4697 Рік тому

    This was an exceptionally educational episode!