Results from the BRESELIBET trial of brentuximab vedotin + chemotherapy for R/R Hodgkin lymphoma

Anna Sureda, MD, PhD, Catalan Institute of Oncology, Duran I Reynals Hospital, Barcelona, Spain, presents the results of the Phase IIb randomized prospective clinical trial BRESELIBET (NCT04378647) investigating salvage chemotherapy alone (ESHAP) or supplemented with brentuximab vedotin (BRESHAP) in patients with relapsed/refractory (R/R) Hodgkin lymphoma (HL). Patients receiving BRESHAP achieved significantly higher metabolic complete remission (mCR) rates, with no difference in toxicity profiles and the success of stem cell collection for autologous stem cell transplantation (autoSCT) between the groups. This study assessed brentuximab vedotin single drug consolidation therapy as an alternative to autoSCT in patients achieving mCR. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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