The Science Behind The Most Underrated Supplement | L-Carnitine
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- Опубліковано 28 вер 2024
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Topics Covered
L-carnitine benefits
l carnitine benefits
Carnitine benefits
Bodybuilding
Fat Loss
Weight loss
Cognition
Fertility
Androgen Receptors
Fatty acids are not broken down into ATP. The breakdown of fatty acids releases energy which is coupled to the synthesis of ATP.
Can you make a video comparing oral VS Injectable L-Carnitine and going through the medical research about dangers in TMAO? Love you channel bro!💸
Ya I was hoping he would talk about the injectables cuz I thought you can't intake an ethacasius dose oraly?
@@evanpanch7143 you can take a sufficient dose orally however you have to dose much higher. I dose at 5g during fat loss phases and I definitely notice the difference
You defs need to talk about bioavailability my guy @nutrition library
I don't think he went into the injectables conversation, because almost nobody is going to want to pin every single day for the relatively minor benefits.
@moreplatesmoredates includes this in his video
In the thumbnail picture he uses Gorilla Mind's Carnitine L Tartrate, best for androgen receptor upregulating and fat loss when used at 4g+. When he speaks about cognitive performance at 10:20, it is explaining ALCAR (ALC or Acetyl L Carnitine) which crosses blood brain barrier easily, taken at 500mg-1.5g. And then plain old L-Carnitine. Make sure you know which you are getting, as they may have different benefits
When is the best time to take l carnitine tartrate to maximize its performance?
@@robmagz I feel positiv effects immediately after ingestion on empty stomach.
Can a-l-car still upregulate androgen receptors and if so how much relative to l-car?
@@robmagz Take about 30mins to an hour before workout
@@supercal333 Nothing I can give you on that, but since alcar passes blood brain barrier the dosage is much less than LCLT. If you were to take as much alcar as LCLT you'd def have cognitive effects, maybe positive maybe negative
You didn't make a distinction in your video between L-Carnitine and Acetyl-L-Carnitine, the latter form is the one mostly responsible for cognitive benefits, while the former is the one most beneficial with regards to energy production.
You forgot a very important part: the L-carnitine formulations. In the studies different formulations have been used where for example acelyl-L-carnitine can pass the brain-blood-barrier while other forms like tartrate or fumarate don't and also to enter muscle cells you need to stack it with high IG carbs (insulin needed).
yeah I was taking ALCAR post-workout wit carbs
This is wonderful. Can you talk more about the dosages, times and cycles of how to take it please?
2 gs with some carbs if possible
Since oral supplementation isn't very bioavailable, it is recommended to take 3-4g. I usually take it 30 mins before a workout on an empty stomach or light food. works well for extra energy and fat loss. I take Carnitine L Tartrate from gorilla mind. I have also tried ALC (Acetyl L Carnitine) and seemed to just give me brain fog since it is an acetylcholine precursor
@@mitchellmarshall7298 that’ll give you stomach cancer. Inject L-Carnotine so your gut microbiota doesn’t convert it to TMAO
L-Carnitines, similiar to creatines benefits fade away once usage is stopped and as creatine, does not require on-off cycling. Bioavailability of L-Carnitine taken orally is about 10% so its recommended to take anywhere from 2 grams up to 7 grams as it is very heavily tolerated and has no adverse effects. You can also get doctor prescribed L-Carnitine via intramusscular injection where bioavailability is 100% so the injected dose is usually anywhere from 200mgs up to 2 grams according to Dr. Kyle Gillett
@@mitchellmarshall7298 how many capsules did you take? I took a while ago didn't notice anything really. Maybe I didn't take enough each time
Love the energy and time you put into your videos!!!
Would love for you to take a look at Vitamin D Deficiency. Traditional Hunter-gatherers Vitamin D blood levels are around 115 nmol/L while the current recommended Vitamin D blood levels is 40 - 60 nmol/L… Hope this says a lot and it is definitely worth doing some research on this :)
Hey, do you have a link about this by any chance? From what i researched especially from chris masterjohn, the upper limit seems to be around 60 in the presence of enough vit A, otherwise toxicity symptoms occur and kidney stones form.
@RuXueChiew
You are confused about units!
The recommendation is for 40 - 60 ng/ml. You have to multiply that with 2.5 to get nmol/l for vitamin D.
Great videos brother! Could you make a video on L-Carnitine and TMAO? I’d be curious to get your insight and knowledge on if it’s a concern or not. And if it is not a concern maybe you could explain in depth as to why? Thank you!🤝🏼
More plates more dates has a couple vids on it
It is a concern. Most definitely with oral administration
It’s a concern. Be aware of the risks before taking it.
this guy is awesome, all vids are very informative and this dude researches the hell out of everything
If you make a video like this touting potential benefits from studies I think it's very important to include the doses and also talk about the potential risks. You didn't mention conversion to TMAO and the potential negative effects of long term elevated levels of TMAO.
@5kribbles
A very short scan of research confirmed your concerns, and gave me this story:
The gut microbiome converts L-Carnitine into TMAO, which causes arteriosclerosis. Berberine counteracts that effect of the gut mucrobiome.
And yes, the research seems to indicate that it's not just an accociation between TMAO and arteriosclerosis. It's actually causative.
The increase of TMAO with L-Carnitine was very robust.
The research on Berberine was with Coline induced TMAO, not L-Carnitine.
I don't know if it's the same bacteria. So if it works for L-Carnitine too is yet unknown.
Very interesting thank you! @@larsnystrom6698
Who eats L-Car these days. Inject it.
Excellent information, thank you ! Do you have any suggestions on dosage and when to take L-Carnitine ?
Dosage -> 1-2 St (Steak)
Dosage of zero. Don’t take it. It’s not worth the risk.
Acetyl L-Carnitine is the form needed for crossing the blood brain barrier and will also be used by the body. Regular L-Carnitine will not be the right choice to those looking for the cognitive/brain cellular benefits.
What’s your thoughts on L-carnitine L-tartrate?
Tanks for the info
EXACTLY : Those studies on brain benefits were done with ALCRN, not L- Carnitine.
@@Anthony-pq3bzpretty effective for androgen receptor up regulation, so minor performance boost. potential boost in libido and testicular function (seminal volume) as well. good for cardio as it increases bodyfat utilization.
oral l-carnitine does nothing. you need to inject to really feel the benefits an you need to use a really big needle since its almost like a gel..
been using ALCAR before workout. ive become a machine with no tiredness whatsoever....
Alcar is more for cognitive function. L-Carnitine Tartrate is for physical performance.
@sebastiank7287 there is plenty of crossover between the two
Carnitine is great, but you should review beta-alanine and ALCAR. Beta-alanine is a precursor to Carnosine another promising amino acid, that might be more efficient than taking carnosine directly. ALCAR (acetyl-l-carnitine) has an easier time crossing the BBB.
Citrulline is a precusor to Arginine, not Carnitine.
@@jonnull You are right, editing out the Citrulline comment. I think I meant to say beta-alanine, a better precursor to "Carnosine" which is a different amino-acid with some promising health research. Citrulline and other Nitric-Oxide producers are great for a workout but have more conflicting evidence regarding long term benefits.
Bravo sir yet another excellent and informative video! Would love to see a video on vitamin k2 mk4 and mk7 and it's potential to increase testosterone...
Its a nootropic as well, its amazing
On the Andrew Huberman podcast with Dr Gilette they say to ingest at least 3-5 grams of L carnitine to work ...
I am taking 500 mg and it works just fine to begin with.
Okay so I've been researching fitness supplements for the past year and this is the first time ive heard of this L-carnitine supplementation for these purposes. Very interesting
You’re living under a rock….watch mpmd and educate yourself
when ingesting L-carnitine orally doesn't it have a carcinogenic effect and isn't that why injecting L-Carnitine has become so popular with athletes and bodybuilders?
Yup sure does
I took this in liquid form, i didn't feel any difference whatsoever, however, my sweat started to stink so much, it became unbearable. I never had issues with sweating. Even the clothes after washing continued to smell. I do not recommend it at all. It took me maybe 6 months to fix my sweat smell again and if you want to be walking skunk, go ahead hahah. I gave you friendly warning
Yes, but i doubt it's up to the meat
I read about this on the Amazon reviews for the liquid form, but didn't see any mention of it in pill form 🤔
Just take in minimal amount i guess, but I'll never do it again. And if we eat enough meat we should have enough
Didn't notice any effect on my sweat it makes my urine smell terrible though 😂😂
lol no youre just a putrid
Here is my question, during an extended fast how does mitochondria utilize fatty acids without dietary protein is this when muscle loss begins?
I know it’s an amino acid along with taurine that helps with your heart. It builds your heart muscles too. I had a dog that had congestive heart failure and he was eating dog food that didn’t have them in it.. He ended up passing away.. I also know that L Carnitine helps with muscle building..
Love your videos!!.. would you ever do one talking about magnesium?
How much should I take and in which form?
Would like to know too, studies were promising and now I'm all hyped up haha
Orally you should take 5-6 grams but also take with garlic to lower TMAO production in the gut (a side effect not mentioned in this video) but if you're going to pin it straight to your blood stream you can take much less 1-3 grams. TMAO causes cell oxidation which is very bad for the heart. Garlic is very important. I wouldn't take carnitine without taking garlic.
Carnitine I tried a few times my strength increases were wow same day to 3 days of use. Severe headaches within 2-3 days of use like clockwork. I couldn't continue.
L-carnitine tartate vs acetyl-carnitine
What about its low oral bioavailability? What were the required doses and was it L-carnitine or ALCAR?
Just boof it, dude
@@sanduvieru1623 ?
@@Hbarca8 Administer the supplement rectally to circumvent the first-pass effect.
@@sanduvieru1623 instructions not clear! need a tutorial mate
Shit I already take citrulin mallete, beta alanine, creatine, and ton of other supplements. Am I really about to buy this?
Edit did u just say improves power, my mind, and deez nuts!? Sold
you can cut out the citruline and or the beta alanine for the carnitine
@@zakariyawyatt1416 yeah I'm think of cutting beta alanine, it don't see much strength or endurance gains from it but I do like the tingles
Well i need to try this, i am a total noob when it comes to training but i wanna change that and improve my health and general wellbeing
I'd recommend protein powder and creatine, vitamins, zinc, magnisum, D3. You'll end up like us with a basket full of supplements when u make nookie gains just fine without them
@@agentnukaz1715 I do take protein and creatine, and i am considering getting zinc and magnesium aswell as i am aware that they are very good for muscle and strength gains
@@thetruth4654 that's a good idea. Zinc, mag, and D3 may increase testosterone if your deficient. Maybe consider trying gorilla minds, sigma supplement since it has all of those plus Boron and testosterone boosting herbs such as Fadogia, tomkat, and ashwaghanda.
Recommended dosage?
Recommended time of day for supplementation?
With a meal vs without?
Web search is helpful
I’m only going to take this to improve my tsh. It’s always around .45 - .60. Heart palpitations and anxiety every now and then get annoying. Tsh only ever improved when I was on trt but not looking to do that again rn
Does it help with fat loss ?
Just imagine you eat 300gramms of beef =>500mg Lcarnitine. Cavemen did it, so do i.
Have you seen paul saladino talk about how sucralose when paired with a carb increases insulin resistence? I used to take gorrila mind pre workout but quit taking them a few weeks ago once I found this out because they all use sucralose and other 0 calorie sweeteners.
have you seen doctor sebi talk about how all the food were eating to gain weight for the gym is acidic garbage filling the insides of our bodies and brains with mucus causing disease and a brain thats hard on receiving blood and oxygen because its blocked off from the stuck mucus?
Dosage? Timing?
6:20 I guess somebody did not pay for the paper hahahah
stache and hair lookin great my guy
Excellent information 👍🏽💯
Excellent video!
Acetyl L-Carnitine is the best variant by some way to takes
Anyone count how many times he say aerobic?
Great video! But the following three things need to be explained in more detail:
1. What should we take for better atheletic performance: carnitine or acetyl-carnitine?
2. dosage and timing
3. Should carnitine be taken with carbs or on an empty stomach?
The information on google is quite contradictory and confusing!
First 2 days of Oral L-Carnitine and I felt sleepy and goofy happy within an hour, almost like a weird mix of mild euphoria and sedation.
Has anyone experienced this ??
You had me at ATP
what is the first and second most popular? creatine and preworkout?
YOUR INCREDIBLE KNOWLEDGE BLOWS MY MIND. GREAT WORK. BEST WISHES FROM INDIA
Weight loss ?
Please put chapter
thoughts on supplementing with gaba? (heard it might increase HGH)
@nutrition Library do you need to cycle off, and do you take it everyday? Great content, love your channel
I have a bottle now, and I've been sleeping on it. I barely take it.
Any thoughts on l carnitine and potential TMAO production?
I took L-Carnitine before a workout about 45 mins before. The first time, I had a lot of energy and seemed to minimize inflammation and increase energy. However, the second time I took it, gave me lots of gas (aka - smelly farts) and diarrhea. Does this mean I took too much?! It was only around 250mg! I'm also very small framed - 5 ft 3 inches and only 95 lbs. Thanks!
Hello! I always feel, less is more and suggest taking a smaller mg dosage and monitor how you feel after taking it.
Tf? I take 6 grams a day and never had any of these side effects
@@jadhamad2491 what’s tf stand for?:)
but how much L- carnitine should we take to receive those benefits?
Okay I'm sorry if I missed this but do you need to take it everyday?
Thank you for another gem! Is L-Carnitine and Acetyl L Carnitine the same ?
From what I understand, they’re pretty much similar in terms of function…. Acetyl L Carnitine supposedly has better absorption in the small intestine and crosses the blood brain barrier much better. So dosage could be different? Though not entirely sure.
@@petermiljak thank you so much for your reply, I just bought the Acetyl one for better energy at the gym, glad it’s the same. Again much appreciated
is it true if i take L-carnitine orally i would have to take about 3000-4000mg / day for it to be effective because of its low absorption rate
Did I miss the part about recommended daily dosage ?
L-Carnitine can also cause severe heart palpitations.
How does L-Carnitine compare to ALCAR (Acetyl L Carnitine).
Alcar probably crosses the blood brain barrier better and may be better for the purpose of improving cognition.
Can a-l-car still upregulate androgen receptors and if so how much relative to l-car?
I’ve heard that alcar is the best form to take orally, or you have to inject it. Is this correct?
Here before he reaches a mil subscribers💯💯
can you make an video about ac-262?
Senor El Carnitin
Acetlt l carnitine or just l carnitine?
Dosage anyone ?
I heard you can’t take L Carnitine orally and it has to be an inter muscular injection to achieve these benefits. Most states require you to have a prescription for this. Can you address how to take it and recommended doses. Thanks man, another great video
Wow super supplement that no one talks about 🤯 I'm missing this 👌✨ my pre or intra workouts don't have it 🦾😤🦾
I assume L citrulline was more efficient
you have anything on Kava?
Yeah you didn't mention TMAO.
Hi do you know the product Biogen Rage Testo
I thought oral L Carnitine doesn't absorb well
Hey does the same apply to ACETYL L CARNITINE?
Likely
Tell you what, I haven't got time to watch this right now. But first hand advice.... This is the most powerful fat burner I have ever used.
Whilst is ketosis and with an empty stomach and hungry. Have a couple grams of this with water, then do a heard hour of cardio... You can shred down to 3% body fat like this within two weeks!
come on now...
L-Carnitine is literally in almost every single energy drink lol so I don't think it's unpopular.
lol you wouldnt be getting anywhere close to optimal dosage in an energy drink
Man , do you think TMAO issue is a real concern ?
No
HOWEVER! (repeat 10x per minute)
Just the one survey lol 😂
What foods contain L carnitine? I
l-carnitine nuggets.
Steak, fish, chicken, etc
@@Jbills thnx, I'm wondering if I'd benifit from supplementing with l carnatine if I eat alot of meat
@@agentnukaz1715 it could still be beneficial. Taking amino acids in isolation tends to have unique effects
@@Jbills yeah it seems it would be really tough to meet those levels of l carantine. It's like 500mg if u inject it , oral supplement is 4g to meet the androgenic effects. In 4 Oz of beef is 100mg on avg. But I assume it absorbs much better through meat
What about the w-creatine 😏
yay dr berg!
What about TMAO?
Not worried.
I was consistently supplementing with carnitine for a while back in 2020-2021, and had my blood drawn at the tail end of that period. I noticed that, after my blood was drawn, a small unobstructive clot formed immediately in that area and remained for a couple weeks. Do you think it’s at all possible the supplementation and clot were linked?
@@TheAccountification I don't think there is any evidence of L-Carnitine having this effect on the blood. I would rather consider that it was a result of the blood drawing
@@NutritionLibrary can you combine l carnitime with cialis or viagra? A friend of mine who takes this pre workout i think 50 or 100mg (bodybuilder natty or mostly natty). Wanna take it for the androgen benefits in combinationen wirh 50 to 100mg sildenafil on training days
From what I understand raw garlic stops tmao
Can anyone tell me why L Carnitine Tartrate makes me feel extremely frustrated? Even small doses of the powdered form, or what is in some energy drinks. Never heard anyone mention this before.
Plot twist cocaine is in L-carnatine 😆
Ghost energy drink has 1000 mg of L-Carnitine
Derek sells bunk supps, why use product in thumbnail? 🤔
🤡
@@realname60 what a thought provoking and intelligent rebuttal…🤡
however
I always thought L-carnitine was underrated
Title - Most underrated Supplement.
Literally 6 seconds in - "It is actually the third most popular supplement in America."
Instant dislike
In a time where male fertility is on a rapid decline you did a real disservice not delving deeper into the aspects of how carnitine improves fertility
Great. One more essential thing i gotta buy each month im already a broke bitch lol.
I keep hearing this is a dangerous Supplement and it causes TMAO in the body
The only bad thing about this supplement is that it makes my sweat smells like fish. I'm actually serious, not joking at all. Idk why this happens.
Copper helps with that
Bad review didn't get into injectable vs oral or acytl carnatine. Surface level basic info
Dude read the comments. People asking if you need hormone therapy after l carnitine n stuff. These are surface level people
If our body already makes it. Why make more?
I love the liquid. Very beneficial. Also great for sexual health. You’re loads will be lethal protect them at all cost don’t water Jezebels 😂😂😂😂🤷🏻♂️
how the hell is it underrated if it's popular. do you not know what the words mean?
Selling out to Derek? lol