In this video, I show you what happens when you put polyethylene glycol in Boyle's self-flowing flask See the full video here: • Boyle's Self-Flowing F... #shorts
Well, there's are are some where the answer is "Maybe if you wait a very long time." Generally the time is on the 'ten to at least three digits' scale.
@@kh6853 Yes, it would break the laws of physics. You'd either have to have something with 0 mass or 0 friction, or something else that's impossible to be 0.
bahahaha lol lmao hehhehehehehehehehehehh polyethylene glycol is covid 19 vaccine silly boi ..and it is the common ingredient found in all the different kinds of covid vaccines that should tell you something right there ! will the real covid vaccine please stand up please stand up pleace stand up '' im a millennial ,,i went to school after 1985 when the 1920 famous movie actor "the jelly bean man " pres, ronny ray gun said let no child be left behind .and with a stroke of ronnie's pin all education in public schools came to a complete dead stop and ever since to this very day ..but not for long as the elite have figured out a way for us to fix everything by pull out all the carbon dioxide form the air and we will be in heaven
Everytime you see one of these the answer will always be no, perpetual motion has been, is, and always will be impossible, we can't do anything about that
@@meenakshiuprit5557I guess you wanted a "fix " that didn't require the activation of brain cells? You COULD have both left a comment, AND found smthn to say... so really you WERE like those 372, you had nothing to contribute either.
@palmerjacob39 well of course by definition your correct, but what it's NOT is "saying something", which is the language I used... and to dissuade further debate confused by semantics, when I say "say something" I mean to contribute unique thoughts to the situation (being that all the ppl who DIDN'T comment apparently had nothing to add, and a comment without substance suggests he was in that same category)
For those who don't understand: "This is an osmotic laxative, commonly known as Miralax. It makes your digestive system flow, but not a perpetual motion machine."
For those still confused as to why it's not moving: Imagine a very long chain. Even those small ones that hold the pen. Now if you pull on the chain and drop it over a table it might eventually pull the rest of the chain down with it. Now take the end that's on the floor and attach it to the end that's on the table. With out you doing anything you'll notice that the chain eventually doesn't move. It needs something to interact with it. You haven't made a perpetual motion device, you've made a necklace.
The reason it works on the bowl is because the liquid is losing potential energy overall, it gains a bit of energy when it goes up the bowl, but that energy is coming from the liquid that's already falling and pulling more liquid. In boyle's flask the liquid would have to gain more energy than it loses to go up that much
@@geneviva1846it’s a southern American way of saying sarcasm or “lip” or being somewhat argumentative/blunt but usually not intending to be overtly rude or offensive. It’s a humorous way of telling people how you really feel without trying to start an argument. Edit: southern American meaning southern USA. Not South American. Two different things entirely.
@@johntheherbalistg8756 i think you will probably wlll die for sure .you ever look up the ingredients for polyethylene glycol ? its made out of ethylene glycol ..its already running though your veins if you took the jab like 280-300 millions of americans have and now all have symptoms of the jab that is the same for antifreeze...bahahahaha
And don't forget your most common Word used by your opinionáted scholars of the academia that scientifically expláins everything in one Word "bull"followed by childish smiley faces of emotional laughter of uneducated goons
A lot of people eat ramen with the water still in the bowl (like a soup), and I’ve never understood why. Feel like that’s just gonna make your noodles too soggy to be palatable unless you eat super quick.
@@AlCapwnedProductions also the salt gets all concentrated in the water so not only it ruins the noodles but it also turns into the unhealthiest part if you drink it
@@ATartaruga Bruh do you really think eating a packet of salt directly on the noodles is somehow more healthy than eating a packet of salt dissolved in water. You might as well just be drinking the entire soup base when you leave the water out.
The principle that makes this thing possible I think is the fact that this fluid has strong intermolecular forces between molecules so when some of the fluid start going down it drags more down with it. But when it comes to a Boyle's self flowing flask the fluid has not enough potential energy to continue flowing so it stops.
Every single accurate measure of energy change in a system that we have ever made has shown that in interactions, the total energy stays the same (1st law of thermodynamics) and becomes distributed more uniformly (2nd law of thermodynamics). People have spent their LIVES proving, verifying, and even trying to break these laws. They hold true every single time. If you’re interested in the technical reasons behind why, I recommend taking a university-level course on thermodynamics.
Or hide the solar PV strip.... That's how the perpetual motion machine in the Toronto Technology (not science) museum operated. It was also a test of observation skills, as it was clearly visible from a ramp between building floors looking down, but not when one was standing near that exhibit.
The weight of the fluid inside the tube is still higher than the part of the tube on top of the funnel so there is a reverse flow. We can induce a temporary flow by artificially adding bubbles in the fluid but once the bubbles are gone the equilibrium returns
haha I was about to look that up until you said that. I'm pretty sure that's what's in "Miralax" Was on that in the hospital after i broke my femur. Those pain meds will block you up! Polyethylene Glycol for the win!
Clinical fact: since polyethylene glycol (PEG) is so thick, it is used as a polymer coat for the enzyme Adenosine Deaminase (ADA) to make PEG-ADA. In patients with a deficiency in ADA, they cannot make use of the enzyme’s normal function to recycle purines (a category of nucleotides). So, there is a buildup in the substrates Adenosine and Deoxyadenosine (dAdo), which the enzyme normally acts on to create Inosine and Deoxyinosine, repsectively. The accumulation of dAdo inhibits Ribonucleotide Reductase (RR), which is necessary to repair DNA. Areas of high DNA replication subsequently become extra susceptible to dying off, since if a cell cannot repair DNA, it is triggered to undergo apoptosis to prevent a faulty cell making it through the cycle. In the Thymus (small gland between your lungs and behind the breastbone (AKA sternum)), your immune T Cells undergo rapid DNA rearrangement during their maturation with their receptor that will allow it to bind multiple different pathogens when it’s functioning. This rapid DNA rearrangement requires RR to repair any mistakes, but since RR was inhibited from dAdo buildup… these poor T Cells cannot mature since they are selected to undergo apoptosis. So, newborns with an ADA deficiency develop Severe Combined Immunodeficiency. Their B and T Cells do not form since RR is inhibited and cannot help them mature. Thus, after the maternal antibodies (IgG) transferred through breast milk wear off newborns will present with Failure to Thrive, recurrent rare infections, and they will likely pass away at about 3-6 months old unless they get a bone marrow transplant (since this is where B Cells mature) or they can be given… PEG-ADA! Giving patients regular ADA to make up for their deficient enzyme doesn’t work well because ADA rapidly deteriorates in the plasma. So by putting a polymer coat around it, it can last longer and successfully recycle Adenosine and Ado so RR does not get inhibited, and therefore normal DNA synthesis and repair is also uninhibited :) I’m happy some of you find this interesting! For those interested in more: Blc-2 is an anti-apoptotic signal, meaning it PREVENTS your cells from exploding. Blc-2 inhibits the formation of BH123 proteins that can come together to form a channel. If this channel forms on the Mitochondrial membrane, then *cytochrome c* can be released to help form an Apoptosome. Once this forms, the cell will be destroyed. Bcl-2 doesn’t want this, so it blocks BH123 from coming together. Unfortunately, Bcl-2 is in very low concentration in the Thymus, where T Cells mature. This is because T Cells undergo something called Negative and Positive Selection. If their T Cell Receptors (TCRs) do not properly respond to dendritic cells presenting antigens that belong to our own body, they are killed off. This is good because we only want the best of the best T Cells made. So, this is why Bcl-2 is low in the Thymus. We do not want to prevent apoptosis (which is what Bcl-2 does), since we do want to destroy T Cells that aren’t doing their job right. The issue is that in people with ADA deficiency, DNA is not being repaired in general due to dAdos building up and inhibiting RR. So T Cells are especially susceptible to apoptosis because the thymus presents a very low Bcl-2 environment, allowing for little to no apoptotic inhibition. This further explains why ADA deficiency primarily targets immune cells, resulting in Severe Combined Immunodeficiency (SCID).
For those who don't know. Glycol tubes are wrapped around beer lines from keg rooms to keep your beer cold. This is essential for keeping beer cold while traveling through a tap line. The friction of traveling through a tube from keg to tap would warm your beer up without Glycol wraps.
These are two different chemicals with very similar names. The chemical used as coolant/antifreeze is ethylene glycol and the chemical in this video is polyethylene glycol which most often used as a laxative.
It’s not the “friction” in the lines that would warm the beer. There is hardly any friction in a liquid flowing through a smooth tube. Rather, it’s the fact that the lines from the keg fridge are exposed to the ambient air temperature and thus they would act as a heat exchanger for the heat in the room to soak into the beer, and when the cold beer is flowing, they would condense humidity on the lines, causing water damage to cabinetry, flooring, etc. The beer is not continuously flowing - it’s the heat soak from the ambient air temperature while it sits there in the lines, not friction. Also - as already mentioned, it’s not the chemical in the video.
You can Say that again .. polyethylene Glycol is a common compound found in all the COVID vaccines...it's Made from antifreeze for your car's radiator that is Ethylene Glycol...there is a warning on every gallon jug of antifreeze telling You that it is toxic poison to humans and pets ..so i looked up the symptoms of antifreeze poisoning and they are roughly the same as the SIDE effects of the COVID vaccines...it's not the antifreeze it's self that kills You but the reaction to the antifreeze that your internal organs do trying to GET rid of the Polyethylene Glycol or Ethylene Glycol...your individual organs put out antitoxins that are not the same from one organ to another and when these antitoxins mix together inside your body that's when You get all these weird symptoms at the same time..i'm no doctor and no rocket scientist ..but i have been told by doctores to always "read the LABEL" .... i am a chronic asthma patient all My life of 73 years ..at age 6 i was having asthma attacks so offen that something had to be done as i was dying fást .i was Taken to a lab and experimentes on and it was found i am allergic to a type of mold that grows on house dust that exist anywhere and everywhere so rather than having to live inside a climent control dust free bubble t took a series of shots for 3 years once pero weekto alter My DNA..that was not a permanent cure all but allowed me to live.and Yes DNA science was not known to scientist for another 20 years
You can Say that again,! Polyethylene Glycol is one common ingrediente in the COVID vaccines ..it's imposible now to tell You any more as i have two phones and a Chrome book and all they are self deleting My words and text after i spent the time over and over again and again of 5 hours and each time on three different devices of i try to Say anything negetive about the "JAB"
Fun fact: Polyethylene Glycol is also the scientific name for Miralax, the stuff that doctors recommend to ingest in order to flush your system out either prior to a colonoscopy prep procedure, or simply because you’re constipated.
Yup, had to take a bunch with Gatorade in middle school and the texture and smell was horrible😭 Can't look at Gatorade without getting flashbacks now lol
Actually it does: Helmholtz, Gibbs, etc. The problem is to get free free-energy. However, small systems can obtain free free-energy (free-lunches) from a reservoir, unprobable that it seems to be (look for Jarzynski Equality). Unfortunately, if N is the size of the system, the probability of getting free free-energy goes as e^{-N}...
PEG is also useful in protein engineering, especially to increase the size of proteins/drugs at their free amines and thiols, helping to keep them circulating in your body longer. All around cool stuff
For those who don’t know, perpetual motion is the action of a device that, once activated, will keep going without any additional energy required to maintain it
Longer hose, then let it flow down through the tube, then stick it back in the fluid? Maybe the pressure of the fluid moving down with the large air bubble will pull enough up?
The reason it doesn't work is because the chain is being pulled upward by the fluid in the tube and downward at the same time by the fluid in the cup. The tension causes the chain to get thinner and thinner until it rips apart.
My favorite thing about perpetual motion questions is that the answer is always “no”
And yet my brain still always wants it to be possible
Well, there's are are some where the answer is "Maybe if you wait a very long time." Generally the time is on the 'ten to at least three digits' scale.
Is it impossible to build one?
@@kh6853 Yes, it would break the laws of physics. You'd either have to have something with 0 mass or 0 friction, or something else that's impossible to be 0.
The earth moving through space would beg to differ. Or any star or planet for that matter.
Ive never heard action labs pull a "no you idiot" move. Usually he is so chill and nice about stupid questions.
chill does not apply for anything perpetual motion-related
It was weird
Action Labs does a thought experiment and concludes idiocy is conserved, so no point fighting it.😊
How is a question about perpetual motion stupid?
@@ayasha89games66probably because the answer is always "no", if I had to guess.
That was the most passive aggressive science short I've ever seen 😂
bahahaha lol lmao hehhehehehehehehehehehh polyethylene glycol is covid 19 vaccine silly boi ..and it is the common ingredient found in all the different kinds of covid vaccines that should tell you something right there ! will the real covid vaccine please stand up please stand up pleace stand up '' im a millennial ,,i went to school after 1985 when the 1920 famous movie actor "the jelly bean man " pres, ronny ray gun said let no child be left behind .and with a stroke of ronnie's pin all education in public schools came to a complete dead stop and ever since to this very day ..but not for long as the elite have figured out a way for us to fix everything by pull out all the carbon dioxide form the air and we will be in heaven
😂😂😂
😂
Everytime you see one of these the answer will always be no, perpetual motion has been, is, and always will be impossible, we can't do anything about that
@@ya_boi2872 can't you do it in space with the rotating bicycle wheel though ?
"The hardest part about creating a perpetual motion machine is hiding the batteries"
What's this a reference to?
Bro atleast watch the full video before trying to be cool 🤷🏻
Electroboom ?
You're probably 10
why are people insulting you lmao you just made a joke
The sass at the end lmao
372 likes with no comment let me not fix this🤟
@@meenakshiuprit5557I guess you wanted a "fix " that didn't require the activation of brain cells? You COULD have both left a comment, AND found smthn to say... so really you WERE like those 372, you had nothing to contribute either.
Writting a comment without actually making any comment is still a comment. @theoriginalmonstermaker
@palmerjacob39 well of course by definition your correct, but what it's NOT is "saying something", which is the language I used... and to dissuade further debate confused by semantics, when I say "say something" I mean to contribute unique thoughts to the situation (being that all the ppl who DIDN'T comment apparently had nothing to add, and a comment without substance suggests he was in that same category)
😂😂
For those who don't understand: "This is an osmotic laxative, commonly known as Miralax. It makes your digestive system flow, but not a perpetual motion machine."
Every three months or so when I overdue it with hot sauce it almost seems like I turn my backside into a perpetual motion machine.
I prefer the Walter white product better
When reading this I’m like…. Laxaday is polyethylene glycol 3350…. Wowza and we’re ingesting that everyday for some folks….
im allergic to peg, it causes me severe mental distress such as tics, irritability, etc. it's pretty crazy.
@@exlliottt
I've heard many comments about PEG being harmful. Count me out.
For those still confused as to why it's not moving: Imagine a very long chain. Even those small ones that hold the pen. Now if you pull on the chain and drop it over a table it might eventually pull the rest of the chain down with it. Now take the end that's on the floor and attach it to the end that's on the table. With out you doing anything you'll notice that the chain eventually doesn't move. It needs something to interact with it. You haven't made a perpetual motion device, you've made a necklace.
That's a nice explanation
The reason it works on the bowl is because the liquid is losing potential energy overall, it gains a bit of energy when it goes up the bowl, but that energy is coming from the liquid that's already falling and pulling more liquid. In boyle's flask the liquid would have to gain more energy than it loses to go up that much
The whole chain falls down
This explained nothing to me
Thank you
"Hold On, This Whole Operation Was Your Idea" - Anakin Skywalker
That is the most sass I have ever seen in an action lab video.
Hope he keeps the sass train rolling. That was gold. 🤣
What is sass?
@@geneviva1846
Solving
Any
Scientific
Shit
@@geneviva1846look it up
@@geneviva1846it’s a southern American way of saying sarcasm or “lip” or being somewhat argumentative/blunt but usually not intending to be overtly rude or offensive. It’s a humorous way of telling people how you really feel without trying to start an argument.
Edit: southern American meaning southern USA. Not South American. Two different things entirely.
Ah, the Water of Life.
*drinks it and dies*
No, you don't die. It helps with constipation. If you drink too much, it might not feel good, but you probably will not die
@@johntheherbalistg8756 whoosh
This is actually a common medication for constipation, over the counter it's called miralax
@@johntheherbalistg8756 i think you will probably wlll die for sure .you ever look up the ingredients for polyethylene glycol ? its made out of ethylene glycol ..its already running though your veins if you took the jab like 280-300 millions of americans have and now all have symptoms of the jab that is the same for antifreeze...bahahahaha
@@johntheherbalistg8756 He was making a reference to Dune, I think 😅
Wait what was that ending 😂 😂
My man used the best effect he could think of 😂
The More You Know jingle is copyrighted
Made me laugh as well 😂
@@PointsofDataand?
@@PointsofDataF*** copyright
Me after accidentally spilling a bit of my polyethylene glycole:
In this house we obey the law of thermodynamics!
D'oh!
Your name worries me
he whom obeys the law of theromodynamics recognises that reaching 0 kelvin will never be possible
I dont
Well we ignore it at mom's house!
“Could we achieved perpetual motion”
My instant reaction: “NO!” 😂
Mine to😂😂😂
And don't forget your most common Word used by your opinionáted scholars of the academia that scientifically expláins everything in one Word "bull"followed by childish smiley faces of emotional laughter of uneducated goons
I read this in Dr robotnik's voice lmao
If it wasn't No 😂 then we would have been in motors of everything
@@donniebaker5984 the future is now old man 😂
The fluid equivalent of plugging a power bar into itself.
ye, i just said to myself
"Its just gonna stabilize with no flow"
Oh shit I have free power now, thanks 👍
I am gun grip
YUW GUYZ GOT ANEH POWEHR BAHRZ!?
Instructions unclear, Now i have 3rd degree burns
Physics really said: Womp womp.
Underated
Not really
only because of his meth'd up flask....the real flask would have worked its already been showcased elsewhere
“Of course it doesn’t work” was my favorite part 😂😂😂😂😂
Ikr
Boyle was Irish, so his flask will pour continuously if you fill it with whiskey.
😂😂😂
This!😂
Nice touch using the Irish spelling - whilst not unique to Ireland it's definitely separate from Scottish Whisky without the "e"
@@izzabelladogalinii always spell its whiskey, never even knew “whisky” was a spelling
😂❤🎉😅
What ramen does when trying to pour out the water:
Underrated comment ngl😂😂
People didn't get that one
A lot of people eat ramen with the water still in the bowl (like a soup), and I’ve never understood why. Feel like that’s just gonna make your noodles too soggy to be palatable unless you eat super quick.
@@AlCapwnedProductions also the salt gets all concentrated in the water so not only it ruins the noodles but it also turns into the unhealthiest part if you drink it
@@ATartaruga Bruh do you really think eating a packet of salt directly on the noodles is somehow more healthy than eating a packet of salt dissolved in water. You might as well just be drinking the entire soup base when you leave the water out.
"oops, I spilled a drop"
The whole liquid: Ima head out
Edit: why tf are you guys arguing about an empty comment
"I'll have what he's having" ah liquid 💀
@@WatchMoreAnalogHorror
An u200c copy and paste comment is above me
@@Andrei_Anton-C20 it’s not that. I just put an “null” character rhere
He sounded so genuinely disappointed in *us* at the end lol
"Why isn't it possible?"
"It's just not."
Doesn't need any explanation, it's basic knowledge
The principle that makes this thing possible I think is the fact that this fluid has strong intermolecular forces between molecules so when some of the fluid start going down it drags more down with it. But when it comes to a Boyle's self flowing flask the fluid has not enough potential energy to continue flowing so it stops.
Every single accurate measure of energy change in a system that we have ever made has shown that in interactions, the total energy stays the same (1st law of thermodynamics) and becomes distributed more uniformly (2nd law of thermodynamics). People have spent their LIVES proving, verifying, and even trying to break these laws. They hold true every single time. If you’re interested in the technical reasons behind why, I recommend taking a university-level course on thermodynamics.
“Why not you stupid bastard?”
@@YuzinhaSzbut an explanation is interesting
Homer: "Lisa get in here."
Lisa: "Yes dad?"
Homer: "In this house we oney the laws of thermodynamics!!"
Lol that's exactly what I was going say 😂 😂
I was mumbling this when I came across this comment 😅
oney the rules!
Dude, I think you meant to say 'obey'
@@Kilvieo No no, he meant Oney as in OneyPlays. We all know Homer is an avid Oney fan
lol i love the energy of the explanation at the end
I love how sassy he was at the end, as if We're the ones who asked him to try it
Thermodynamics really is the fun police of physics.
Gotta keep the world fair somehow
I am gun grip
"The most difficult thing about building perpetual motion machines is figuring out where to hide the battery." ©
Or hide the solar PV strip.... That's how the perpetual motion machine in the Toronto Technology (not science) museum operated. It was also a test of observation skills, as it was clearly visible from a ramp between building floors looking down, but not when one was standing near that exhibit.
How fucking original...
@@Ienteredmynamecorrectly-lt3nu that's why he copyrighted it ©️
That ending made me feel like I was personally being insulted for watching the video.
Clicked for the science. Stayed for the sass.
And I'm loving it.
*197 missed calls from Isaac Newton*
257 likes and no comments? Let me change that.
@@Kuballini Support troops incoming
@@Kuballini⚡️💁🏿♂️⚡️
6 days later and you’ve grown from 257 -> 708
"I may not have a brain gentlemen but I do have an idea."💀
I'm sure I've heard this quote and I remember the delivery and moment being epic.
@@curiousnerdkitteh The blue jelly dude from heros vs monsters (I think that's the name of it).
"Could we achieve perpetual motion?" - No, the answer is always no.
I knew from the start it obviously wouldn't work, but the end sass hurt anyway
The weight of the fluid inside the tube is still higher than the part of the tube on top of the funnel so there is a reverse flow. We can induce a temporary flow by artificially adding bubbles in the fluid but once the bubbles are gone the equilibrium returns
You'd think at least once the correct answer would be "yes, it is magic"
Magic is science that we don't understand, so the answer would never be "magic", it'd be "we don't know yet"
She's just purring the whole time you're brushing her and it's so adorable
The hardest part about achieving perpetual motion is hiding the power source.
"Tonigh on SMNN, scientist have found alien eja..."
Nah bro, blud got some 99.1% pure-
Ejaculate.
“It was found off the coast of Laos. Scientists are testing the sample as we speak.”
AYO
@@PayzTheSithGamerThe coast of Laos
One *couldn't* imagine Boyle happy
Myth of Sisyphus reference?
Almost like a self-fulfilling siphon effect
Fun fact : Polyethylene glycol is commonly used as a medication for constipation
And polyethylene oxide is used for lube
haha I was about to look that up until you said that. I'm pretty sure that's what's in "Miralax"
Was on that in the hospital after i broke my femur. Those pain meds will block you up!
Polyethylene Glycol for the win!
@@randalthor6872 Also the major component of prep solution to empty you out for colonoscopies.
Easy now to see why 😂
Surely there is a ready-made joke in there somewhere!
I stayed til' the end... don't ever talk to us like that again 😂
Clinical fact: since polyethylene glycol (PEG) is so thick, it is used as a polymer coat for the enzyme Adenosine Deaminase (ADA) to make PEG-ADA. In patients with a deficiency in ADA, they cannot make use of the enzyme’s normal function to recycle purines (a category of nucleotides). So, there is a buildup in the substrates Adenosine and Deoxyadenosine (dAdo), which the enzyme normally acts on to create Inosine and Deoxyinosine, repsectively. The accumulation of dAdo inhibits Ribonucleotide Reductase (RR), which is necessary to repair DNA. Areas of high DNA replication subsequently become extra susceptible to dying off, since if a cell cannot repair DNA, it is triggered to undergo apoptosis to prevent a faulty cell making it through the cycle.
In the Thymus (small gland between your lungs and behind the breastbone (AKA sternum)), your immune T Cells undergo rapid DNA rearrangement during their maturation with their receptor that will allow it to bind multiple different pathogens when it’s functioning. This rapid DNA rearrangement requires RR to repair any mistakes, but since RR was inhibited from dAdo buildup… these poor T Cells cannot mature since they are selected to undergo apoptosis.
So, newborns with an ADA deficiency develop Severe Combined Immunodeficiency. Their B and T Cells do not form since RR is inhibited and cannot help them mature. Thus, after the maternal antibodies (IgG) transferred through breast milk wear off newborns will present with Failure to Thrive, recurrent rare infections, and they will likely pass away at about 3-6 months old unless they get a bone marrow transplant (since this is where B Cells mature) or they can be given… PEG-ADA! Giving patients regular ADA to make up for their deficient enzyme doesn’t work well because ADA rapidly deteriorates in the plasma. So by putting a polymer coat around it, it can last longer and successfully recycle Adenosine and Ado so RR does not get inhibited, and therefore normal DNA synthesis and repair is also uninhibited :)
I’m happy some of you find this interesting! For those interested in more: Blc-2 is an anti-apoptotic signal, meaning it PREVENTS your cells from exploding. Blc-2 inhibits the formation of BH123 proteins that can come together to form a channel. If this channel forms on the Mitochondrial membrane, then *cytochrome c* can be released to help form an Apoptosome. Once this forms, the cell will be destroyed. Bcl-2 doesn’t want this, so it blocks BH123 from coming together. Unfortunately, Bcl-2 is in very low concentration in the Thymus, where T Cells mature. This is because T Cells undergo something called Negative and Positive Selection. If their T Cell Receptors (TCRs) do not properly respond to dendritic cells presenting antigens that belong to our own body, they are killed off. This is good because we only want the best of the best T Cells made. So, this is why Bcl-2 is low in the Thymus. We do not want to prevent apoptosis (which is what Bcl-2 does), since we do want to destroy T Cells that aren’t doing their job right. The issue is that in people with ADA deficiency, DNA is not being repaired in general due to dAdos building up and inhibiting RR. So T Cells are especially susceptible to apoptosis because the thymus presents a very low Bcl-2 environment, allowing for little to no apoptotic inhibition. This further explains why ADA deficiency primarily targets immune cells, resulting in Severe Combined Immunodeficiency (SCID).
Peg me
Jesus Christ enough words?
@@I_Like_747s that’s medicine for ya
nice to know the weird self flowing fluid actually saved lives
@@I_Like_747s you have a hard time with that? When was the last time you read a news article?
My favorite thing about perpetual motion is the idiots thinking they're smart for pointing out the obvious that perpetual motion isn't possible
Bruh that’s a magical thermodynamic breaking fluid if I’ve ever seen one
Also a major component in both some automotive coolants AND the prep solution you ingest to prepare for a colonoscopy!
Yay!
They have you swallow antifreeze for the colonoscopy????
Didn’t know such a fluid existed but that would’ve been cool!
It's basically a plastic. So it's actually chained together.
Egg-white behaves pretty similiar.
Sheesh, what a convoluted way to call me stupid 😅
This is just like the update for Minecraft where if you went on stairs you would keep going.
For those who don't know. Glycol tubes are wrapped around beer lines from keg rooms to keep your beer cold.
This is essential for keeping beer cold while traveling through a tap line. The friction of traveling through a tube from keg to tap would warm your beer up without Glycol wraps.
These are two different chemicals with very similar names. The chemical used as coolant/antifreeze is ethylene glycol and the chemical in this video is polyethylene glycol which most often used as a laxative.
It’s not the “friction” in the lines that would warm the beer. There is hardly any friction in a liquid flowing through a smooth tube.
Rather, it’s the fact that the lines from the keg fridge are exposed to the ambient air temperature and thus they would act as a heat exchanger for the heat in the room to soak into the beer, and when the cold beer is flowing, they would condense humidity on the lines, causing water damage to cabinetry, flooring, etc.
The beer is not continuously flowing - it’s the heat soak from the ambient air temperature while it sits there in the lines, not friction.
Also - as already mentioned, it’s not the chemical in the video.
The hardest part about making a perpetual machine is finding where to put the batteries
Walter White: The polyethylene glycol keeps flowing. No matter what.
You can Say that again .. polyethylene Glycol is a common compound found in all the COVID vaccines...it's Made from antifreeze for your car's radiator that is Ethylene Glycol...there is a warning on every gallon jug of antifreeze telling You that it is toxic poison to humans and pets
..so i looked up the symptoms of antifreeze poisoning and they are roughly the same as the SIDE effects of the COVID vaccines...it's not the antifreeze it's self that kills You but the reaction to the antifreeze that your internal organs do trying to GET rid of the Polyethylene Glycol or Ethylene Glycol...your individual organs put out antitoxins that are not the same from one organ to another and when these antitoxins mix together inside your body that's when You get all these weird symptoms at the same time..i'm no doctor and no rocket scientist ..but i have been told by doctores to always "read the LABEL" .... i am a chronic asthma patient all My life of 73 years ..at age 6 i was having asthma attacks so offen that something had to be done as i was dying fást
.i was Taken to a lab and experimentes on and it was found i am allergic to a type of mold that grows on house dust that exist anywhere and everywhere so rather than having to live inside a climent control dust free bubble t took a series of shots for 3 years once pero weekto alter My DNA..that was not a permanent cure all but allowed me to live.and Yes DNA science was not known to scientist for another 20 years
You can Say that again,! Polyethylene Glycol is one common ingrediente in the COVID vaccines ..it's imposible now to tell You any more as i have two phones and a Chrome book and all they are self deleting My words and text after i spent the time over and over again and again of 5 hours and each time on three different devices of i try to Say anything negetive about the "JAB"
Rule 1 of physics: it’s never perpetual motion.
God really said: nuh uh
That ending was amazing 💀
Fun fact: Polyethylene Glycol is also the scientific name for Miralax, the stuff that doctors recommend to ingest in order to flush your system out either prior to a colonoscopy prep procedure, or simply because you’re constipated.
Yup, had to take a bunch with Gatorade in middle school and the texture and smell was horrible😭 Can't look at Gatorade without getting flashbacks now lol
CUUURRSSEEEE YOOUU BOYLE'S SELF-FLOWING FLASK
He just called each viewer an idiot in the politest way
Only those who expected to see perpetual motion.
People who knows: 😶
Remember guys, free energy does not exist
Democrats think everything is free nowadays
Actually it does: Helmholtz, Gibbs, etc. The problem is to get free free-energy. However, small systems can obtain free free-energy (free-lunches) from a reservoir, unprobable that it seems to be (look for Jarzynski Equality).
Unfortunately, if N is the size of the system, the probability of getting free free-energy goes as e^{-N}...
@@wellesmorgado4797thermodynamics is about to ruin your fun
@@wellesmorgado4797 "unprobable"?????
Did I just get called an idiot by a rocket scientist? I'm not smart enough to know for sure 😂
Law of conservation of energy says: energy cannot be created nor destroyed
That's some very incorrect interpretation. It instead says the total energy and mass in a closed system stays the same.
I feel like some perpetual motion machines really should work but physics bends over backwards to ensure its not possible.
PEG is also useful in protein engineering, especially to increase the size of proteins/drugs at their free amines and thiols, helping to keep them circulating in your body longer. All around cool stuff
Foregoing that, the end point always needs to be lower than the start with any kind of siphon
That end was way harder than I ever expected from your channel!
This is my favorite condescending, nerd, “Duh!” Video ever.
Nicely done Sir. I didn’t know it was a thing but you are winning.
Polyethylene glycol is Miralax
Yes this is happening in your ass.
The Water of Life!
You have some serious talent!
I've never seen so much masculinity in a single video
If you wanna be homophobic, at least do it right.
Gf’s dad: what are your intentions with my daughter?
Me:
“The More You Know
★
😂😂😂😂😂😂😂😂😂😂
I've never heard him be sassy before!! 😂😂😂 This was everything!!😅😅😅
And this is the shit they are putting in vapes this is crazy
They put Propylene Glycol in. The one in the video is a completely different compound.
I appreciate the attempts at personal motion
I didn’t know that Charles Boyle was a mathematician
Watching you fumble Pure Vessel was... tough. I've been radianting him almost everyday just cause I love the fight so much.
I swear people argue that perpetual motion exists like there life depends on it🤦
Instructions unclear my coffee escaped and is now going downstairs! what do I do! 😭.
The chunks in it at the beginning we're going to make me sick, I kept gagging 🫡💀
"Aw man i spilled a bit"
Liquid: "WE LEAVE NO MAN BEHIND BOYS"
I needed this 10/10 so satisfying
For those who don’t know, perpetual motion is the action of a device that, once activated, will keep going without any additional energy required to maintain it
Longer hose, then let it flow down through the tube, then stick it back in the fluid? Maybe the pressure of the fluid moving down with the large air bubble will pull enough up?
The hardest part of discovering perpetual motion, is hiding the battery
“Could we attain perpetual motion” Only you would try something like this! And I’m here for it.
What is polyethylene glycol and what is it used for
Bro thought he found a real life chunk loader😂
It is possible, there just isn't any air flow to warrant a gap to fill. In other words liquids can not fill in on themselves. (The more you know).
As a Greg tech player (a very hard Minecraft tech mod) as soon as I heard polyethylene I had shivers down my spine
He just beat us over the head with "how gullible are you?" 😅
Wait a sec i saw the blue thing away
You had me wanting it to work so bad. I had 10 one billion dollar ideas before you shamed my ass for thinking it would work. 😂
The hardest part of designing a perpetual motion device is trying to decide where to hide the battery.
Dude lured me in.... and then... smacked me upside the head.
If you close your eyes during the first 5 seconds, you'd swear this was about to be Mint Mobile commercial
"SIR YES SIR" ahh liquid 💀🙏
The reason it doesn't work is because the chain is being pulled upward by the fluid in the tube and downward at the same time by the fluid in the cup. The tension causes the chain to get thinner and thinner until it rips apart.
Is this the same stuff they put in alcohol or am I just an alcoholic?
The attitude at the end is 👩🍳💋!!!
Two things this world will never see. Perpetual motion, and an honest politician.
true 🙏