It’s my understanding Metformin increases insulin sensitivity. Could the inhibition of complex 1 somehow signal the increase in mitochondrial number over time?
44:00 could be that the intracellular medium and the intramitochondria medium are different and for some reason those proteins need to be done inside the mitochondria or (say) the wont fold correctly. Or maybe there wasn't a move of genes, the nucleus could have already the genes and only got deleted form the mitochondria.
It is a very long podcast, but every minute worth your time. I've learned so much in these 2hours and 22 minutes.
Loved this interview. Just ordered Navs book on Amazon. Can’t wait to read it. #KickAss 100YrOld.
The best podcast ever.
Awesome podcast!
Great podcast. I’ve had to order Metabolism at a Glance to understand it!
This was a good one!
I'll have to listen to it again, though!
Excellent Podcast 🙂👍
Very complex topic. I have to rewind. Please have a sequel.
It’s my understanding Metformin increases insulin sensitivity. Could the inhibition of complex 1 somehow signal the increase in mitochondrial number over time?
44:00 could be that the intracellular medium and the intramitochondria medium are different and for some reason those proteins need to be done inside the mitochondria or (say) the wont fold correctly. Or maybe there wasn't a move of genes, the nucleus could have already the genes and only got deleted form the mitochondria.
Oh how fair we've come since "oh no protein and mTOR"
AMPK activates autophagy and burning fat from the liver so there is no mystery in how metformin works.
👍🇧🇷 fantastic
❤
Having the library by the fireplace
Peter , try Jain diet .. no non veg , no milk products , no root vegetables, no leaf .. also no liquor ..
It might be easier/faster to produce and degrade mitochondria as needed, when there are less genes and regulatory mechanisms. Speed > defense
Your take on supplement PQQ?
Everything that was bad is now good, peroxide. Everything good is now bad. I'm gonna stop listening and just do everything in moderation.
Tell them you rob banks... you meet interesting people, the hours are good, it pays well, you're home every day, and you get federal holidays off.
Nobody understands with these two are talking about why is this even on UA-cam?