Pheochromocytoma | Symptoms and Treatment
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- Опубліковано 16 сер 2024
- Lesson on Pheochromocytoma: Symptoms and Treatment. Pheochromocytoma is a medical condition caused by a catecholamine-secreting tumor formed by chromaffin cells within the adrenal medulla. This tumor secretes excessive amounts of catecholamines, leading to a variety of symptoms including hypertension, a pounding headache and tachycardia. Pheochromocytoma has a similar presentation to a paraganglioma, which originates from sympathetic nervous tissue as opposed to pheochromocytoma. However, both pheochromocytoma and paragangliomas are managed and treated similarly, so often are categorized together.
Pheochromocytoma is often idiopathic, but can be associated with a variety of genetic conditions including MEN2. Diagnosis of pheochromocytoma involves measuring catecholamine levels and catecholamine breakdown products known as metanephrines in the plasma and urine. When pheochromocytoma has been diagnosed, surgery is often required in order to resect the tumor; however, careful treatment and management is required prior to surgery for successful outcomes. I hope you find this video helpful. If you do, please like and subscribe for more videos like this one :)
Also, please check out some of my other endocrinology lessons.
JJ
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As a resident, I did the anesthesia for a pheochromocytoma removal. It was a bit if a roller-coaster ride, but we were ready for that and everything turned out fine.
Was surgery painful!? How long were u in hospital for ? Cause doctor said I might have to do surgery as well :(.
@@ace_stealth251ace9 I'm sorry, you are asking a question that has little to do with what I said. I never did surgery for this issue.
@@ace_stealth251ace9 ,hello...
I had a right adrenalectomy last Friday..I was discharged on Monday.
Am feeling better.
I went off all drugs immediately after the surgery.
The surgery took around 4 hrs...I took longer to get off anaesthesia ( as I was informed but it was not dangerous
@@mercykaruchia where did you have the surgery?
@@willweed6168,in Nairobi, Kenya...(Agha Khan University hospital)
Hi
Many thanks for your video , i suffered this condition aged 26 which almost cost me my life due to being treated for stress.
Aged 46 I had a second Pheo and wasnt ignored though disbelieved..
I am aged 70 now and being investigated for a third pheo.
My three 24 hour urine tests were high and after 10 blood test i am now due to have a Normetanephrine blood test.
i always thought i caused the tumor as i am an anxious person but now realize its the other way around.
Many thanks Susan . Leicester UK .
Some of us have to wait FOREVER to get a diagnosis....not fair. Take care Susan!
Was it malignant or benign .?
Oh wow I didn’t know you could get the tumor again & I can’t get the dr to remove mine I’m always shaking & bad anxiety & high blood pressure plus other symptoms
@@Watjenu I would find another doctor.
Oh wow I can’t believe you had it removed & it came back,I’m extremely nervous & shakey I’ve seen 2 specialist & they seem to think it don’t need to be removed,my last visit they said my blood pressure was what they call a medical emergency & my pheo tumor is the suze of a egg
Too bad damn near 99% of the time dr just says you have depression , anxiety, or your crazy and moves on while your organs die
Also propanlol is still not a good option even when other therapies fail
I’m on Propanlol and I still get the adrenaline in the stomach feeling!! 😢
I've been on Doxasosin 1mg and 100mg Metoprolol for 6 months. Been having heart rate and BP problems since 2019. Doctors "don't know why" or what is causing it, except for one. He suggested I may have Pheochromocytoma and reffered to Endocrinologist. Almost two years of suffering and only 1 out of the 22 doctors I have seen came up with a probable diagnosis. I have been through urine and blood tests and all cone back normal. These Pheochromocytomas can be tricky and have false positives on tests. I see the Specialist on May 6th....finally.
@@T69bonez how did it go? It’s been a few months now
@@bpohive he died
Datz d saddest part. So much money v pay as bills and it doesn't get diagnozed and they say vrythinv is stress and frame us as psychic
MRI is superior to cat scan in detecting a pheochromocytoma plus a cat scan exposes the patient to the radiation from approx. 300-400 chest X-Rays. So if your doctor/s prescribes a cat scan to rule in or out a pheochromocytoma, he/she either is not aware of these facts, ignores these facts , or has a financial interest in having patients utilize the cat scan in which cases, then find another doctor, (it's your body/your life), protect it.
In addition, only have an knowledgeable/experienced surgeon with a positive outcome history perform your adrenalectomy AND same goes for the anesthesiologist for the adrenalectomy (since this is an exceedingly delicate procedure for an anesthesiologist as well) at medical facility with a positive outcome history in this most delicate of operations in BOTH the open or laparoscopic adrenalectomy.
Best of luck and health.
Can you share as per what guideline MRI is superior to CT scan in detecting pheochromocytoma? Thanks in advance.
See I’ve heard it’s the other way around. Specifically a 3D CAT scan is superior for finding these types of tumors.
I studied and diagnosed one patient at our clinical. It was a nice experience to diagnose this condition.
Hi I'm 26 now suffering from the prblm please help me Or guide me..
B/p: 200/140
Normetanefrons 3000 around, done ct abdomen. But they reported there is little mass in the right adrenal but not conformed pheochromocytoma.. Then stoped the investigation.
@@naveenkumarreddy6758i would seek another opinion.
Or get more demanding from doc..
My heart rate was pounding and I was at work and I didn't lift anything heavy. I started to feel very sick causing me to feel nauseous, vomiting and fast heart rate (Tachycardia) . My manager called paramedics and they said my heart rate was at 160 which was dangeroues. I go to ER then I tell them all my symtpoms. I get admitted to hospital and my blood pressure was quite high. I had the symptoms of "Pheochromocytoma" as I also had shaky hands, sweating, anxiety and my body would twitch and shake which is quite scary. In order to be diganosed I needed a CT scan and a PET scan and when I did both of those scans, it was confirmed I had it. My "Pheochromocytoma" has been in my body for 7 years. How did they know? in 2016, I had an ovarian cyst burst and my endocronlogist pulled up my past CT scan back in 2017 when I mentioned I have PCOS and he was able to see in the old CT scan that this tumor was there and it was never mentioned to me. I am on heart meds and BP meds and surgery will be soon!
Thanks for sharing. This is incredible and glad they found it! Hope surgery goes well 😊
@@Katie-vy5rd Hey no problem! I did surgery 5 months ago, I feel amazing now. Still doing my check up with the drs but I'm all good! 😄
@angg9669 It must’ve been very hard… and you made it through. Congratulations 🙌
Hope you are doing well.
Wish you good health and happiness always ❤
@@priyapathak1582 thank you ❤️🙏🏻 it was definitely scary but I made it through!
Well done understood very well .. keep it up helpful for medical students like me and for others ..
Thank you
I’ve just been diagnosed with a pheochromocytoma it’s 20 cm by 18 cm and it was found after I had a c section. And almost having a stroke. Now I’m just waiting for the next steps in getting it removed
What were your symptoms?
Splenectomy at age 12 following trauma.
Then I have have developed a lot of complex illnesses including CLL, CMV pericarditis, CMV hepatitis, diabetes, heart disease, Osteoporosis #T4, T7, T9 and AF. I have 2 x 2 stents and cardiac ablation last year that did not resolve AF. I discovered that I had a couple of left adrenal abnormalities and one has continued to grow fairly rapidly into a Pheochromocytoma. This explains treatment resistant AF and some other symptoms. PET scan 3 days ago has confirmed 5 cm tumour but no secondaries for the surgeon and I am just waiting for a date. Hopefully my health will improve after surgery and I can go on to lead a happy, health and productive retirement. I mention the splenectomy because i think it could be at the route of a lot of my illnesses. I have 8 medical professionals looking after me and I was a nurse in drug health and mental health for 43 years until I retired last year. Despite my stubborn determination I am still a bit afraid of the surgery as there are risks and I have some complexities to consider including insulin dependent diabetes, AF and a whole raft of medications to control hypertension and BSL. In the last month the tumor has given me increasing pain which keeps me awake sometimes. I take Targin sparingly. My cardiologist had a light bulb moment when he found out about the adrenal tumor and thinks that is the reason for treatment resistant AF and other symptoms such as intermittent episodes of confusion and headaches. I have pain under the lower left rib. Hopefully a couple of small fatty growths on the right adrenal don't turn sinister. I would love to retain one adrenal gland!
Wow. Your are definately strong. God be with you through all this and all the best.
ua-cam.com/video/Jv8IqJm6q7w/v-deo.html
Tomorrow, I start the urine test for this. Exciting.
Nurse Mandy just did my urine test yesterday. Hope yours was negative!
Just did mine and mine are elevated,im going for a CT scan of my adrenals. Im super nervous 😩
Doctor only gave me a blood test for it. Want to do the urine test as I hear they're more accurate
@@applepie3610 Insist on tests dont be ignored . good luck x
Nova how did everything go with you Urine test? How everything worked out. I was just prescribed blood pressure pills but all the symptoms I have im freaked out scared and nervous my doctors says I have an MRI on my abdomen and see what going on and he said I have to do a urine test
Someone please help me I’ve had Lyme disease twice in the past, had multiple ear infections, and have ibs. And literally for the past 3 years I’ve had anxiety and depression, feeling off balance, random chest pain when taking a deep breath, eye snow, tinnitus, and mental issues. I’m 16 and have gone to the doctor many times with multiple urine tests and other c.a.t. scans and mri tests done. I have none of those symptoms of pheochromocytima but I’m just trying to rule this out hopefully. And I don’t know if thid had anything to do with it but I have gone through severe mental abuse and stress with having a parent abuse alcohol and see them wither from age 9-13(I was 13 when the symptoms started).
Buddy, you're not alone. I also suffer from a lot of paranoia and anxiety about my health. I'm also feeling real physical symptoms and searched until I found this video about pheochromocytoma. Some of my symptoms could be another syndrome or nothing at all. Same to you buddy. I'm here for you, though and I hope you're feeling better now. Many people have different ailments but it's how we think or live with them that matters.
Really really thank you sooo much I had understand pheochromocytoma just now👍🏻👍🏻👍🏻👍🏻
I love these lectures ty so much
If anyone haz questions for me I am having these symptoms and have also been through it before, many trips to ER & finally a Rt. adrenalectomy.
Hi may i contact you through Facebook.... I had several went to ER for pulpiation and leads to hypertension.... But all my labs were normal at the end. So we decided to discharge.
Hi. Did you have constant high blood pressure and headaches? Did you lose weight before surgery?
So are you suffering from THIS?
Hope you are healthy and happy my friend ❤️
Hello. I have seen many doctors and I feel like I need help. Would you be willing to talk to me?
I'm having episodes off extremely high heart rate after eating (with different side effects) and have tachycardia. my dad had one so its likely I have it. starting my urine test today. wish me luck
How are you?
How are u now?
How are u
Any progress in diagnosis?
This is a great video! Thank you!
so what do you diagnose with when someone has completed a scan of their stomach twice with nothing being found but have elevated levels of Adrenalin and meet the most symptoms?
Have MIBG 123 scan. Best for finding Pheo.
I feel the same way, adrenaline in my stomach but no palpitations because my doctor put me on Propranolol. This is so frustrating.
@@Dreamangelsrebornnursery how can we detect this by urine test
Very helpful. Thanks!
So my doc thinks I have an adrenal gland tumor. The night before I landed myself in the hospital with V-tach I had a glass of wine. And I was in non sustained v tach on and off for about a full day before I went to the Er because I thought it was just my regular heart palpitations that I get. Maybe i have one of these been having severe unexplained panic attacks since I was 19. I'm 27 now
A tip: watch series on Flixzone. I've been using it for watching lots of of movies during the lockdown.
@Zahir Sonny yup, I have been using flixzone for months myself :)
@@zahirsonny7689 ...what does that have to do w/Blakes medical problem?
Any updates?
Helpful video 👍
lol doctor tried to tell me i had this i just laughed and walked out for real... kinda regret it now i should go see a doctor
I hope you are okay
Would this type of tumor cause extreme, unrelenting chronic pain in the area of the tumor? Temperature changes kill! I’m in agony 75% of the time. It radiates to my right ear and up the back of my head near the occipital region. I also have chronic tinnitus on this side.
My day is spent actively trying not to flare up the pain.
Doctors can’t find anything on scans. I have very high blood pressure. I’m 34. I’ve had this pain since I was about 23. I can feel something moving around in my neck when I palpate it.
The pain originates from a very specific spot. If I press on this spot, it feels like I’be been shot. It also is excruciating when I stop applying pressure to the area. The weather changes flare up this pain as well, specifically cold.
Also, I have a glomus tumor under one of my fingernails. So I know I have the genetic mutation for these types of tumors.
The one on my fingernail is EXCRUCIATING if I accidentally whack it on something or if it gets too cold.
Literally takes my breath away if I hit my finger on something in just the right spot. This is what my neck pain feels like… this exact type of pain, only in my neck. I’m desperate to find answers and get better.
I am so over being in pain all the time. I want my life back.
Ask for a PET-scan
I am your promocytoma patient please help treatment
Great❤
Thnk you so much sir . clean and clear explanation 😁
I’m not sure if I have this or not But I have a lot of the basic symptoms, and been to multiple doctor’s associated with Hypertension and Tachycardia.Ruled out many things and still not found a answer. I am on a medicine Right now that lowers my BP and is working but I still get very Hot all the time and am fatigued most of the time, doctors don’t really seem to care just throwing me to the side. Idk I just really want to know what is wrong with me. I’m not sure how many young people it affects but I am only 12 so Idk.
You need to see a type of M.D. specialist called an endocrinologist. An M.D. who specializes in this branch of medicine will be able to determine whether your problem is being caused by an “endocrine gland” (i.e., a hormone-producing organ) such as the pituitary gland, the thyroid gland, the pituitary gland, one of the adrenal glands, or yet another gland, or whether it is related to another organ dysfunction, such as a problem with the ovaries or kidneys. In the meantime, you are doing the right thing by educating yourself on medical topics and looking for answers everywhere you can. I wish you all the best - don’t lose hope, and keep being your own best medical advocate! People brave enough to do this always are best off in the end results!
Have them test for this
P
How is your sleep? Maybe the hypertension and fatigue is being caused by sleep disordered breathing/sleep apnea/UARS. It might not be this, but this is something doctors don’t usually consider in younger patients.
Kierra. Go to an endocrinologist. Sounds like your thyroid.
Thank you 😊
zit would be helpful if you used layman's terms given most people watching are not medical professions.
Had a 5 cm tumor, had no symptoms what so ever, my blood tests were perfect, the only way we saw somehting was through images... was a healhty 31 old woman :) Had an adrenalectomy for my left adrenal gland.
Hi, can You tell how are You feeling after adrenaloctomy? Do You see any changes in Your body functioning etc.?
So I have high urinary metanephrines and my bp used to cross 200 at night during attacks that lasted few mins.But my CT Scan and MRI reports of whole abdomen came normal.I am just 23 now and it seems to be a borderline case? Maybe that's why the tumour isn't caught in imaging bcoz it's too small.
Do you get excessive sweating randomly...
Thank you sir^^
My normatenephines were 1950.. 18 months ago .. i was tested again last week and they came back higher.. CT tomorrow.
Hey. How you doing now. Any updates?
@@Vanshika2323 thanks for asking.. they couldn't locate a tumor.. I'm waiting on results from a ct on the brain, I have a large arachnoid cyst on the left near the cerebellum close to the brain stem.. I've recently been get really bad hot flushes and night sweats.. also through the day.. trouble focusing, sensitive to light and sound, pain at the base of the skull.. it could be causing some problems just waiting on reports. I'll keep you updated. Cheers.
Update.. I have Eagle Syndrome.
Amazing
Could teo unknown lesiins on both kidneys be phochromocytoma?Needing further imaging
Can you make addison's disease and Cushing syndrome please?
Can a patient have pheochromocytoma without tumor?
Nope, the disease is precisely characterized by a tumor.And catecholamines rushes can be caused by many other conditions
Damn I wish I watched this before my exam lol
My dr diagnosed me with this several years ago & I have all the symptoms except I’m gaining weight not loosing weight & I’m always fatigued,the specialist said it’s the size of a egg & I can’t get the dr to remove it!!
Find one who will because it will get bigger and symptoms will get worse! Could kill you
Did they remove it yet?
Still not removed
I jist saw thru wuest my old blood work or urine it showed a very wnd of normal. But low metanephrine. I have bee having symptoms pf cushings disease. For years i have had lots of weird symptims and two lesions one on each kidney and a simple cyst that was 8cm on my kdney.Any feedback?
What about paraganglioma?
Symptoms are the same as pheo (when it is secreting), but it has different location than pheo.
Is 99 pg/ml metanephrine too high? Hypertension and tachycardia present with fainting.
I take propanolol and tiaziac, kinda works, but I still have episodes of severe tachy. Had an epatch holter monitor for a while, just got the results back and I had episodes of 260+ in my sleep that somehow didn't wake me up. Bout to gets me an implant monitor, and that 24 hour piss test jug lol.
Doxazosin and Metoprolol have helped me a bit. Doxazosin at 1mg and Metoprolol 100mg ER. Id like to get an increase on tbe alpha blocker. 1mg just isnt cutting it in the middle of the day.
My mother diagnosed pheochromocytoma..😪😪😪😪😪 doctor said that its very critical condition and operation. What should i do?
uhhh, get the operation.
Let them operate! She has to get rid of that Tumor. Sometimes it spreads, but if you don't let them operate she may have a stroke! Sorry it took so long to reply
I’ve been dealing with this for about 10 years now,& symptoms get really bad sometimes.I’ve been to 2 specialist here & they don’t want to do surgery they said the surgery is to dangerous due to my blood pressure is always high 🤷🏻♀️
Please tell me does it cause infertility in female after surgery???
Classic triad: headache, hypertension & hyperglycemia
How can primary aldosterisn be related to this?
it's not?
This is what killed my father.
I’ve had a chest x ray and it was clear is it possible they missed it ?
Yes
Yes!!! I went back and forth to the doctor for almost a year before they figured out why I was getting the headaches and blood pressure sky harbor high!
I have one on my right adrenal gland
I just done adrenalectomy. both my adrenal glands were removed completely because of bilateral pheos
Hi.. same is the case here. How your doing now? I hope all is fine.
Sir you forget 10%rule of pheochromocytoma and nest aperiance
10% rule is not valid anymore.
I have 1.6 cm tumor on my adrenal gland and have bout 98% of the symptoms of this.
Get on top of it immediately! You will require a few months of recovery and hopefully it want spread like mine did
My normetanephrines free 160valueand remain aal good
What is problem
🥰🥰🥰🥰🥰🥰🥰
PHEO- CHROMA- CYTOMA
DOMO- ARIGATO- ROBOTO