Oh my Allah... i can't stop laughing each time i watch your videos: Dr medicosis: ok! If you didn't watch my previous videos, your chance to understand this topic i ZERO! 😂😂😂
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You are absolutely brilliant and really have a gift when it comes to teaching! I have told everyone about your channel and wish you all the success! Thank you so much for your top quality work ❤
Thank you once again. A doctor who once doctored my husband passed away from ALL in January, 2021 after one year of treatments. He was 48. So incredibly sad.
Wow I'm so surprised that you're not a doctor. Your lesson and video are so much better than what I've learn from hospital. Thanks for sharing the knowledge.
I am creating a nursing case study question set for RN's preparing for NCLEX-RN and loved your RDW videa as well as the ALL video (also, I am mom to a person with Down syndrome). Can you share a common value of RDW% for a T21 patient with ALL RDW%? I cannot find an actual example value online anywhere for my made up lab report
Acute...the patient is younger ? does not count for acute myeloid leukemia. Acute means rapid in this context. But still, remarkable video and abo is on !
Great video, so recently my nephew of 5 years of age was diagnosed with PRE-B ALL which was a terrible news for us, we fought through it, his first biopsy showed more than 95% blast cells in his bone marrow, however they didnt make it to his blood stream, and his other test was fine as well some cpf or cpr some spine test to see if the brain is fine or not I dont really know I'm not a doctor, Anyway, we started off his treatment and immediately even through in his first few weeks of chemotherapy he started showing good improvements like no more bone pains and could start to walk again and do some normal children chores again, we started seeing hope and him being an amazing warrior started battling hard, he started eating a lot which is quite common since his medical team told us because they started giving him steroids and we were happy that our son is doing well diet wise, he has started to gain weight. Long story short it has only been a bit more than a month into his treatment and his last major biopsy, I call it major because it was supposed to show the percentage of the blast cells in his bone marrow because in that biopsy they also took a tiny bit of his bone as well. The doctors said that the could not calculate the percentage of the blast cells because there number was very less so the machine couldn't calculate it. There are a few things that I'd like to add here, I'm a bit concerned about how chemo can have effects on reproduction, and also his gene panel showed ETV6-RUNX1 fusion. Anyone that can help me understand a bit would be much appreciated. Anyway, what my concerns are that is he doing really fine? I mean we can see the improvements in his health but I'm not a doctor so I cannot know for sure, if please you could share some insights. Thanks One thing that I would like to add here for everyone is Do not lose hope if you are given this horrible disease. Always be hopeful and there is light for sure at the end of the tunnel. Peace
I went here to understand, why it's hard to get cured of this disease. My family is heartbroken because my older sister's nephew died the other day because of this type of leukemia. I just hope that scientists may find other treatments that have promising results especially when chemo drugs stop working.
seriously i dont know why youtube prioritizes these lame crashcourse videos, and videos like yours are impossible to find. Thankgod i subscribed or i dont think I would of found you again
Hi my name is Raymond Batisai My nephew Denzel Mavhunga is 8 years old .He now has relapse after only 3 months .We are looking for help for stem cell transplant We are looking funds to find the process in Zimbabwe where we come from there are no resources .Please help
Thank u so much sir..i can understand clearly each n every point😊but i have 1 doubt sir..u told ALL occurs in less than 14yrs..but in the last question 21yr old male had ALL...i am little bit confused sir
I have a question if i made a bone marrow test and the result was 0.001 leukimia blood left in my bone marrow then how much time do i need for treatment and taking chemo
OKAY SO, I have a presentation on this and I wanted to confirm a piece of information with you. So there is the type of classification which divides ALL according to morphology, immunology and genetics (which I want to assume is the same as cytogenetic, correct me if I am wrong). And then there is the classification depending on which lymphocyte precursor is being affected, whether that be the T or B lymphocyte. Anyways, I was planning on using the classification based on morphology etc and briefly (in the introduction) speak about the genetics regarding ALL; however, I was planning on mostly speaking about the gene translocation on chromosome t(9:22) and t(12:21) and rather just presenting the other types of mutations. Anyways, could you please tell me if I have understood correctly all this info? And do you agree that I should talk more in depth about the classification I told you about. Bear with me, I know it is a long post but hopefully I have expressed myself correctly (english is not my first language).
My wife and I lost our just turned 2 year old son 7 months ago to Aml. He had MLL gene rearrangement or subtype KMT2A or 11q23. He had a translocation between chromosomes 6 and 11, t(6;11). He received cytarabine, daunorubicin, etoposide, gemtuzumab ozagamicin then mitoxNtrone and cytarabine. He relapsed after the second chemo which signified refractory Aml which had a poor prognosis. Decitabine with mylotarg was then used. He died shortly after from within 4 months of treatment. Some side effects he had were bloody nausea and diahrea. Horrible bloody mouth sores. He was in pain all over. His right eye was covered by a leukemia pool that ended up bleeding.He had a lot of liquid in his lungs which they thought was pnemonia. He ultimately died from a brain bleed within 24 hours caused we think by the chemo.
@@MedicosisPerfectionalis U should make page on fb about ur new comming video series..most of people dont know u...Ur channel and method is excellent soon u will be in top ranked...
At the risk of sounding dumb, I want to ask something, I don't understand the classification of ALL, what is the meaning of pre B all and pre T all, there is increased proliferation of lymphoblasts right, what is the meaning of B and T here
A 46-year-old female patient presented with nose bleeding, she had pallor but no icterus or cyanosis, spleen was enlarged 1 cm below the right costal margin and there was mild hepatomegaly. CBC: WBC - 124,2 х 109/L, Band Neutrophils - 5 %, Segmented Neutrophils - 15 %, Monocytes - 10 %, Eosinophils - 0 %, Basophils - 0 %, Lymphocytes - 5 %, Blasts 65 %. Since they don't mention what kind of blasts there are, what other ways are there to differentiate between ALL and AML?
iv been through the whole set of videos and now have a great understanding of hematology. Thanks alot for the great videos. could you pls explain what u mean by WBC being 100,000. But the question in the video says 50,000?
Hey! Thanks a lot for watching...I think you misunderstood the WBC count point...I did NOT say, that WBCs will be either < 10,000 or > 100,000...I said that the WBC count can range from less than 10,000 up to >100,000...So leukemia can have WBC count of 8,000 , 20,000 , 50,000, 100,000 or 130,000,...etc...The WBC count can be anything....Hope it helps :)
Thank you so much for your videos. You made most of your discussions seem like a walk to the park compared to the books that I've been reading for hours and made me feel like I'm being punished in hell lol
Because the bone marrow is diverting all of its resources in making tons of lymphocytes, and sacrificing “crowding out” all the other cell lines (e.g. RBCs and platelets). Does that make sense?
1 think where is the mention of units? like you're talking about WBC and say 100,000 do you mean 100,000/MicroLiter? Why not just mention the units? Other than that your videos are amazing! so much better than my prof teaching which is kind of sad lol my hematology course has 7 professors lol
Thank you so much 😊 You’re right, I should have added the measuring units. It’s just common practice among physicians to refer to normal WBC count as 4,000 to 11,000
♥️ Cardiac Pharmacology: www.medicosisperfectionalis.com/
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😊😊
How are you not a doctor???
I've reached a new level where I watch your videos for fun.
😁😁😁
It says a lot about you.
You are a great person who is passionate about knowledge and education...I am honored...Thank you 😊
SAME HERE I LOVE YOUR COMMENTARIES 😂
Thanks a million!
YES YES I was about to comment the Same thanks a lot MEDICOSIS
Me too!
I’m starting to like this hematology thing because of you, thank you for making it so fun to listen to 😂💖
Wow 🤩
likewise
Oh my Allah... i can't stop laughing each time i watch your videos:
Dr medicosis: ok! If you didn't watch my previous videos, your chance to understand this topic i ZERO! 😂😂😂
Haha 😂
Thank you so much for watching!
@@MedicosisPerfectionalis how do we know the previous videos. There's no outline .please can you direct me. Thanks
@@SylviaAputazie the heme onc playlist fam!
Best teacher ever seen😍
U r far more magnificient than anyone else
Genius u are 👍👍
Stay safe keep going😇
Thank you so much 😊
💊 👨🏫 Antibiotics Lectures: www.medicosisperfectionalis.com/products/courses/antibiotics/
💉 📜 My Notes, cases and courses www.medicosisperfectionalis.com/
😍🖼Animated Mnemonics (Picmonic): www.picmonic.com/viphookup/medicosis
📗 Get my notes in pdf files at www.medicosisperfectionalis.com/
If you like my videos, please consider leaving a tip at www.paypal.me/perfectionalis/
Why it's ALL ..it's can be AML also ..please explain..?
Incorporating Ethics was cool :)
50 hematology 💉 *cases*: www.medicosisperfectionalis.com/
You are absolutely brilliant and really have a gift when it comes to teaching! I have told everyone about your channel and wish you all the success! Thank you so much for your top quality work ❤
Thank you so so so much, dear...I am truly speechless! Thanks 🙏
I wish you were my lecturer for all my courses. Very simple, and trust me it takes a lot for me to understand something.
Thank you so much 😊
I appreciate you!
How do you manage to teach these topics sooooo well when you're not a doc?!!!!!😭😭
I just love ❤️ medicine!
@@MedicosisPerfectionalis you're a genius ❤️❤️❤️ thank you for making these topics so easy for us ❤️
video is kinda lacking...(med student)
Thank you once again. A doctor who once doctored my husband passed away from ALL in January, 2021 after one year of treatments. He was 48. So incredibly sad.
Excuse me, why does he passed away? Is he allergic to the chemotherapy or else or other reasons? I also have ALL.
Awesome!!!! Dude where was ur channel all these years.
Hiding in the haystack 😁
Wow I'm so surprised that you're not a doctor. Your lesson and video are so much better than what I've learn from hospital. Thanks for sharing the knowledge.
My pleasure 😇
I am creating a nursing case study question set for RN's preparing for NCLEX-RN and loved your RDW videa as well as the ALL video (also, I am mom to a person with Down syndrome). Can you share a common value of RDW% for a T21 patient with ALL RDW%? I cannot find an actual example value online anywhere for my made up lab report
You are brilliant, funny, a helper, and a doctor. What else to wish?
Thank you for your contribution !
Thank you so much 😊
he said he's not a doctor...
You deserve more views! I honestly forget that I am studying when watching your videos. Thanks!
How do I watch the videos in sequence. How can I get that outline so I follow them topic after topic
Go to my channel. Click on playlists, and choose “hematology”.
ALL level 3 survivor here. Nice explanation.
Thank you so much!
How is your health now?
@@MedicosisPerfectionalis I got cured in 2005 and I am very much healthy and fit now.
OMG! I just stumbled into your channel and thank God I did! Your videos are really helpful for my board exam preparations. Good work bro 😄
Thanks a million! Good luck to you!
I just want to see the face behind this voice 😂
:)
📝 Download my handwritten notes: www.medicosisperfectionalis.com/
Acute...the patient is younger ? does not count for acute myeloid leukemia. Acute means rapid in this context. But still, remarkable video and abo is on !
I LOVE LOVE LOVE THE WAY YOU EXPLAIN THINGS.
Thank you so much 😊
Medicosis Perfectionalis Btw Im studying Medicine in Alexandria,Egypt. Your home country! May I know where did you study medicine? :)
Amazing! Have one month left for my MD Pediatrics exam..your videos have helped me a lot.Thank you so much.
😬😬😬
You are so great ! Excellent presentation and very simple😍❤️
Thank you so much 😊
hey medicosis, it's not "periodic" it's per- iodic acid shiff
You’re correct! Thank you!
Great video, so recently my nephew of 5 years of age was diagnosed with PRE-B ALL which was a terrible news for us, we fought through it, his first biopsy showed more than 95% blast cells in his bone marrow, however they didnt make it to his blood stream, and his other test was fine as well some cpf or cpr some spine test to see if the brain is fine or not I dont really know I'm not a doctor,
Anyway, we started off his treatment and immediately even through in his first few weeks of chemotherapy he started showing good improvements like no more bone pains and could start to walk again and do some normal children chores again, we started seeing hope and him being an amazing warrior started battling hard, he started eating a lot which is quite common since his medical team told us because they started giving him steroids and we were happy that our son is doing well diet wise, he has started to gain weight.
Long story short it has only been a bit more than a month into his treatment and his last major biopsy, I call it major because it was supposed to show the percentage of the blast cells in his bone marrow because in that biopsy they also took a tiny bit of his bone as well. The doctors said that the could not calculate the percentage of the blast cells because there number was very less so the machine couldn't calculate it.
There are a few things that I'd like to add here, I'm a bit concerned about how chemo can have effects on reproduction, and also his gene panel showed ETV6-RUNX1 fusion. Anyone that can help me understand a bit would be much appreciated.
Anyway, what my concerns are that is he doing really fine? I mean we can see the improvements in his health but I'm not a doctor so I cannot know for sure, if please you could share some insights. Thanks
One thing that I would like to add here for everyone is Do not lose hope if you are given this horrible disease. Always be hopeful and there is light for sure at the end of the tunnel. Peace
I went here to understand, why it's hard to get cured of this disease. My family is heartbroken because my older sister's nephew died the other day because of this type of leukemia. I just hope that scientists may find other treatments that have promising results especially when chemo drugs stop working.
seriously i dont know why youtube prioritizes these lame crashcourse videos, and videos like yours are impossible to find. Thankgod i subscribed or i dont think I would of found you again
Thank you so much 😊
Incredible way of teaching.. You're a lifesaver bruh♥️
Thank you so much 😊
Wait a minute...who drew that picture?! I’m cracking up over here 😂 you’re messed up in a perfect way
:)
Thank you. Thank you, Thank you .... ❤❤
You are so welcome!
In the 2nd case the 21 yr old guy, why should it be ALL? Why not AML or chronic leukemia? Just wondering
Blasts are > 20% makes acute leukemia more likely...His age bracket and testicular issues makes ALL more plausible than AML.
Love your videos, extremely helpful and fun to listen to. You’re awesome!
Thank you so much 😊
Hi my name is Raymond Batisai My nephew Denzel Mavhunga is 8 years old .He now has relapse after only 3 months .We are looking for help for stem cell transplant We are looking funds to find the process in Zimbabwe where we come from there are no resources .Please help
Thank u so much sir..i can understand clearly each n every point😊but i have 1 doubt sir..u told ALL occurs in less than 14yrs..but in the last question 21yr old male had ALL...i am little bit confused sir
Awesome..best of its kind! Make more videos please!
Thank you so much 😊
I will
Amazing. Thanks a lot for simplifying ALL. Your hematology videos are 💯💯🔥🔥👏
amazing video as always ❤
Thank you!!
I have a question if i made a bone marrow test and the result was 0.001 leukimia blood left in my bone marrow then how much time do i need for treatment and taking chemo
Talk to your oncologist
wth do you mean by you're not a doctor? lol explain pls !
Walker Donna Hernandez Amy Lopez Brenda
OKAY SO, I have a presentation on this and I wanted to confirm a piece of information with you. So there is the type of classification which divides ALL according to morphology, immunology and genetics (which I want to assume is the same as cytogenetic, correct me if I am wrong). And then there is the classification depending on which lymphocyte precursor is being affected, whether that be the T or B lymphocyte. Anyways, I was planning on using the classification based on morphology etc and briefly (in the introduction) speak about the genetics regarding ALL; however, I was planning on mostly speaking about the gene translocation on chromosome t(9:22) and t(12:21) and rather just presenting the other types of mutations. Anyways, could you please tell me if I have understood correctly all this info? And do you agree that I should talk more in depth about the classification I told you about. Bear with me, I know it is a long post but hopefully I have expressed myself correctly (english is not my first language).
My wife and I lost our just turned 2 year old son 7 months ago to Aml. He had MLL gene rearrangement or subtype KMT2A or 11q23. He had a translocation between chromosomes 6 and 11, t(6;11). He received cytarabine, daunorubicin, etoposide, gemtuzumab ozagamicin then mitoxNtrone and cytarabine. He relapsed after the second chemo which signified refractory Aml which had a poor prognosis. Decitabine with mylotarg was then used. He died shortly after from within 4 months of treatment. Some side effects he had were bloody nausea and diahrea. Horrible bloody mouth sores. He was in pain all over. His right eye was covered by a leukemia pool that ended up bleeding.He had a lot of liquid in his lungs which they thought was pnemonia. He ultimately died from a brain bleed within 24 hours caused we think by the chemo.
I’m very sorry to hear 😢
Thankyou 😊
My pleasure!
there's discrepancy in poor prognostic factors in ALL, Pro-B-cell ALL actually has a poor prognosis (Source - Kumar and Clark)
Your channel is a blessing, thank you Doctor Medicosis
I am honored! Thank you, Eiliya!
thank you sooooo much medicos. god bless you
Thanks!
Thanksssss❤
My pleasure!
Wowwww! Love from India! :)
Thanks 🙏
Listen in 1.5 × speed
Thanks me later ☺️
Hello so your not a doctor as I understand?The videos are great!
Thank you...for nice explanation....
very nice lecture simplified easy for internal exam and board exam , you will not concentration for a moment.Thanks alot
My pleasure...thank you:)
Very nice
Thank you 🙏
U man just nailed All special pathology Every lecture is awesome...i luv u yrr
❤️❤️
@@MedicosisPerfectionalis U should make page on fb about ur new comming video series..most of people dont know u...Ur channel and method is excellent soon u will be in top ranked...
Can you add coagulation cascade? I can't find anything yet. thank you! By the way I love your videos, they are amazing.
Great news! It's here: goo.gl/XrhddJ
At the risk of sounding dumb, I want to ask something, I don't understand the classification of ALL, what is the meaning of pre B all and pre T all, there is increased proliferation of lymphoblasts right, what is the meaning of B and T here
Pre-B cells are more immature than B cells.
A 46-year-old female patient presented with nose bleeding, she had pallor but no icterus or cyanosis, spleen was enlarged 1 cm below the right costal margin and there was mild hepatomegaly. CBC: WBC - 124,2 х 109/L, Band Neutrophils - 5 %, Segmented Neutrophils - 15 %, Monocytes - 10 %, Eosinophils - 0 %, Basophils - 0 %, Lymphocytes - 5 %, Blasts 65 %.
Since they don't mention what kind of blasts there are, what other ways are there to differentiate between ALL and AML?
To watch your videos as a member is $149/month???😵💫😵💫😵💫 Common sense, anyone?🍷🚫
I really appreciate ur channel existence on UA-cam 🥺❤️ Thank u alot
My pleasure 😇
Thank you so much very amazing.
Thank you 🙏
Would you please help me by sharing?
or Mirror, Minor & milder :) & thnx for the videos.
/DR Mahmood Ramazan :)
I don’t understand!
Hi just a quick question, can a patient be in "remission of leukemia" but actually still have it? (15 y/o male with down syndrome ALL), thank you!.
Leukemia 💯 well understood because of you🔥
Thank you ☺️
iv been through the whole set of videos and now have a great understanding of hematology. Thanks alot for the great videos.
could you pls explain what u mean by WBC being 100,000. But the question in the video says 50,000?
Hey! Thanks a lot for watching...I think you misunderstood the WBC count point...I did NOT say, that WBCs will be either < 10,000 or > 100,000...I said that the WBC count can range from less than 10,000 up to >100,000...So leukemia can have WBC count of 8,000 , 20,000 , 50,000, 100,000 or 130,000,...etc...The WBC count can be anything....Hope it helps :)
oh! i get it now. Thanks alot for getting back so soon. :)
Of course...Good luck!
you are doing a good job. God bless you
Thank you so much :)
you’re my superman .. thank you so much forever
Thank you 😊
You are a lifesaver🥺
Thank you 🙏
1:59
❤ medicosis perfectionalis ❤
👏👍
you are just perfect!
Thank you, dear!
Thank you so much ❣️lots of love from nepa
My pleasure 😇
I can't believe you're not a doctor, you know so much that you're basically a doctor. It's a shame you don't treat patients, you would be the best.
Thank you so much for your videos. You made most of your discussions seem like a walk to the park compared to the books that I've been reading for hours and made me feel like I'm being punished in hell lol
Haha 😂
I am so delighted that you found my videos helpful!
Thank you 🙏
plz introduce yourself i am curious
It’s a secret 🤫
Tomorrow is my prelims exams
Good luck!
But, what are prelims exam? 🤷♂️
thank you so much your videos ate amazing
My pleasure 😇
Can you please help me by sharing?
Thank you for posting this video, it was so helpful!!
But it is TdT not tDt
What are the chances of survival 5 year old has 80% leukemia ?
I went through 4 years of treatment when I turned 18
How is your health today?
Best medical channel I have ever seen.
Thank you 🙏
It is only affecting lymphocyte, they why anemia, thrombocytopenia(bleeding)?
Because the bone marrow is diverting all of its resources in making tons of lymphocytes, and sacrificing “crowding out” all the other cell lines (e.g. RBCs and platelets).
Does that make sense?
@@MedicosisPerfectionalis yes..... thankyou
ALL is the most common cancer in pediatrics, but in Down syndrome patients AML M7 is most frequent.
Blurred
1 think where is the mention of units? like you're talking about WBC and say 100,000 do you mean 100,000/MicroLiter? Why not just mention the units?
Other than that your videos are amazing! so much better than my prof teaching which is kind of sad lol my hematology course has 7 professors lol
Thank you so much 😊
You’re right, I should have added the measuring units.
It’s just common practice among physicians to refer to normal WBC count as 4,000 to 11,000
heyyy you said are not a doctor?????
I don’t practice...I teach!
did you just say you're not a doctor ??????? how on earth
30 Jan
Allah bless you 🌹
You too
you have missed the genetic part (NOTCH, RANX genes)
Thank you!
I can’t possibly cover everything about ALL in one video.
@@MedicosisPerfectionalis no problem just wanted to share my thought :)))
You are literally a lifesaver, I support you on patreon and owe you so much more
I appreciate you so much!
Obtain a curte order is it standard in All countries? Or only USA??
Edd Gould anyone?
Thank you very much sir.
my teacher ileen😂 watches your video's .No more headaches.
Var caught
Thank you so much
You're most welcome!
how is he not a doctor he is smarter then my profs