RNA interference/RNA silencing/RNAi mechanism.

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  • Опубліковано 30 лис 2017
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    mbasic. Vipin-Sha...

КОМЕНТАРІ • 366

  • @shaikimran1132
    @shaikimran1132 4 роки тому +121

    How many of you are irritated by byjus and vedantu ads

  • @mkouser5020
    @mkouser5020 4 роки тому +59

    Thank you sooo muchhhh u made RNAi very easy for me i was so tensed and when i watched this i was likeeee how should i thank uu♥️

  • @suja605
    @suja605 3 роки тому +9

    Thankyou so much sir. I wasn't understanding this particular topic in my class. Now I am all clear. I am so grateful. :)

  • @gulshanhaque3837
    @gulshanhaque3837 3 роки тому +6

    thank you so much for such a great explanation ❤️

  • @soniakashyap6491
    @soniakashyap6491 4 роки тому

    Sir that dsrna virus y transpoon ho sakta mtlb jb hamari y plant body affect hogi tb vo hamere ander aaye tho m plant m complimentary dsrna kese dalte h?

  • @prathamkumar7229
    @prathamkumar7229 5 років тому +1

    From where the tranposons come.

  • @kuldeeparora2768
    @kuldeeparora2768 3 роки тому +7

    thanks for making this topic to get into my head...

  • @anujgupta8447
    @anujgupta8447 5 років тому +10

    I want to ask you
    that you tell ds complementry rna come from any virus having rna as genetic material then how this rna is complementary to ss rna of melodigyne incognitia . Please reply

    • @SajitaKu
      @SajitaKu 5 років тому +2

      I'm also confused at that point..good question bro

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 роки тому +4

      Its actually much more complicated than what its sylabus. You see the DS RNA is then made into a Silencing Complex. One of the RNA strand is made into "Guidestrand? which will guide the silencong complex silence the mRNA of the virus while the other strand is degraded. Thats the very simple explaination of how the silencing happens. There is also other things like the Argonaught protein and the RISC thingie. See this video, it explains all that. But you dont have to worry abput it all if ypu are here for NEET or Boards. :) m.ua-cam.com/video/cK-OGB1_ELE/v-deo.html

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 роки тому +1

      Its actually much more complicated than what its sylabus. You see the DS RNA is then made into a Silencing Complex. One of the RNA strand is made into "Guidestrand? which will guide the silencong complex silence the mRNA of the virus while the other strand is degraded. Thats the very simple explaination of how the silencing happens. There is also other things like the Argonaught protein and the RISC thingie. See this video, it explains all that. But you dont have to worry abput it all if ypu are here for NEET or Boards. :) m.ua-cam.com/video/cK-OGB1_ELE/v-deo.html

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 роки тому

      Its actually much more complicated than what its sylabus. You see the DS RNA is then made into a Silencing Complex. One of the RNA strand is made into "Guidestrand? which will guide the silencong complex silence the mRNA of the virus while the other strand is degraded. Thats the very simple explaination of how the silencing happens. There is also other things like the Argonaught protein and the RISC thingie. See this video, it explains all that. But you dont have to worry abput it all if ypu are here for NEET or Boards. :) m.ua-cam.com/video/cK-OGB1_ELE/v-deo.html

    • @ramakrishnareddy1967
      @ramakrishnareddy1967 3 роки тому +1

      It is there in akash module entire process explained for your doubt but it is not necessary

  • @mdwasi8575
    @mdwasi8575 4 роки тому +7

    You are also best for master level .God bless you,thank a lot.

  • @user-mt7hs5sx6z
    @user-mt7hs5sx6z 3 роки тому +5

    Bst explaination ....u make me crystal clear about dis topic ...✌️

  • @hirakjyotideka1082
    @hirakjyotideka1082 3 роки тому +1

    Sirjee ek baat batau, nematodes during infection apne genes chor deta hein plant cells ke andar??? Wo virus thode hi hein..

  • @MehenazSultana
    @MehenazSultana 5 років тому +5

    Sir agrobacterium se gene Kya tobacco plants K growth K suruwath mein dete Hain...

  • @jyotisnatanwar446
    @jyotisnatanwar446 5 років тому +2

    Thank you such nice knowledge by your veido

  • @shahnawazhossain2740
    @shahnawazhossain2740 3 роки тому +3

    If totally protein synthesis stopped , then how the tabacco plant will survive??

    • @shraddhashetty206
      @shraddhashetty206 3 роки тому +2

      The total protein synthesis of the plant doesn't stop....only the gene(mRNA) of the nematode is inactivated and prevented from forming it's respective proteins which cause the disease.

  • @suchitajoshi8461
    @suchitajoshi8461 4 роки тому +1

    Sir please mera ek doubt hai rnai ko lekar ....apne jo btaya lecture mai vo sab samjh aya..but ncert mai ek line di hai jisme likha hai ki parastie will not survive due to rna interference... please isko clear krr dijiye.....vo specific protein konsa hai jiske na milne se nematode survive nhii kr pa rha hai..please sir..reply!!!!!!!!!!!!

  • @sumanpal3380
    @sumanpal3380 4 роки тому +2

    thank you sir for clearing my doubts

  • @edcullen417
    @edcullen417 6 років тому +20

    does an organism have to wait for being infected so that it can regulate its genes by using rnai mechanisms???

    • @arpitachougala6340
      @arpitachougala6340 5 років тому +4

      No we dont have to wait gor the organism to be affected.thats why we are using agrobacterium vector
      to carry the gene of interest from complementary rna to the plant cell.I think this may be th ans

  • @ayshasiddiqui413
    @ayshasiddiqui413 3 роки тому +2

    Thanku very much !! U just nailed it understood in one go !

  • @dailygs655
    @dailygs655 2 роки тому +3

    Thank you so much for such a descriptive lecture about RNAi before that I think tht wow how hard to learn it is and after watching this I am like how so sily 😂😂🙈✌💫...

  • @raghibakbar2821
    @raghibakbar2821 6 років тому +3

    I am tuoght about it in my bio class but even though i could not understand it but now its clear

  • @Harshsharma-qj4bu
    @Harshsharma-qj4bu 3 роки тому +2

    Thanks our big brother to help us in such a beautiful explanation

  • @sadanvs5072
    @sadanvs5072 6 років тому +1

    Sir what is sense and antisense rna

  • @samridhipunj3916
    @samridhipunj3916 5 років тому +1

    sir what is sense and antisense rna?????

  • @Divyasingh-pc4sb
    @Divyasingh-pc4sb 3 роки тому +5

    It was a amazing lecture 👍

  • @sailatkuri7598
    @sailatkuri7598 3 роки тому +1

    Wher does mRNA get silenced in plant cell or nematode cell

  • @kavitapashine8381
    @kavitapashine8381 6 років тому +1

    clear and awesome explaination..thnks..

  • @khushboodhiman6877
    @khushboodhiman6877 3 роки тому +1

    Thank you for this awesome lecture

  • @deleeppatel8987
    @deleeppatel8987 6 років тому +37

    those who dislike. this wonderfull video
    may be they do not aware about
    translation

  • @anaghasubbaraya8842
    @anaghasubbaraya8842 5 років тому +2

    it was really a good lecture bhai...thank you

  • @d.k824
    @d.k824 5 років тому

    thanks, but transgenic host konse hote h plz tell me

  • @sahilkuniyal3122
    @sahilkuniyal3122 5 років тому +1

    Thanks for your contribution sir 🥰🥰...And sir ek baat puchne the ki..sir ye RNA interferencing AIDS k liye use kyu Nahi Hoti...and
    Jo immunisation wali technique wo bhi kyu use Nahi Hoti h

  • @pinki3560
    @pinki3560 4 роки тому +10

    Ds mRNA (Complimentary) mRNA se kese bind krega...bhaiya Aapne incomplete btaya h ...RISC k bare me btao

    • @dheerajraturi2460
      @dheerajraturi2460 4 роки тому +2

      Bhai tereko pta ho to btade. M yehi dekhne aaya tha jo mila nahi

    • @pinki3560
      @pinki3560 4 роки тому +1

      @@dheerajraturi2460 shamu biology ki video me btaya h risc k bare me vo dekh le

    • @Poetic.rajvir
      @Poetic.rajvir 4 роки тому +1

      DICER IS ALSO HERE

  • @meerakundariya9062
    @meerakundariya9062 3 роки тому +2

    Thank you sir
    I understood very well ☺️✌️✌️👍👍👍👍

  • @kaimsardarni2928
    @kaimsardarni2928 5 років тому +2

    Sir I need your help .......

  • @dr.nitin_kumar1164
    @dr.nitin_kumar1164 6 років тому

    Bhai y to bta y D's RNA ham plant k under dal the h ya nematodes k,

  • @thefeveroffreefire6220
    @thefeveroffreefire6220 6 місяців тому +1

    Thank you so much sir,
    I was very confused about this topic from a month and now it is crystal clear..🤩

  • @snekasneka2833
    @snekasneka2833 3 роки тому +1

    Hi sir... I have a small doubt.. From where the complementary ds rna comes... Please reply to this message

  • @vlogsjunction5763
    @vlogsjunction5763 5 років тому +13

    Thankyou for clearing my doubts nd yess u got ur new subscriber and a person to like nd share each vdos of urs bcz i know if tht vdo helps me thn othrs definitely will... ❤

  • @priyasatapathy5945
    @priyasatapathy5945 5 років тому +3

    thank u..sir ..i never understood this so cleary ..before u taught this

  • @akshita9918
    @akshita9918 3 роки тому +2

    Thank u soooo much sir this really helped me a lot

  • @96vishakhaverma48
    @96vishakhaverma48 6 років тому +1

    Thanku bhya😊

  • @devendrapatel5650
    @devendrapatel5650 6 років тому

    Sir DsRNA mRNA se kaise bind karata hai

  • @sarim5593
    @sarim5593 5 років тому +1

    Why sense and antisense strand produced in host not in pathogen..

  • @yashchaudhary3228
    @yashchaudhary3228 5 років тому +1

    sir can u plzz explain the agrobacterium more cleary

  • @GurshaanGaming
    @GurshaanGaming 2 роки тому +1

    Oh yes ,I was looking for this.

  • @bioblast2961
    @bioblast2961 3 роки тому +1

    When double standard RNA is made inside that little bit, then inside the human body or inside the plant body, why it will make a single stand and if it is still there then how will it be connected with single standard and other double standard

    • @kuldeeparora2768
      @kuldeeparora2768 3 роки тому

      RNA is always single stranded that means initially it is present in single strand in our body and this single stranded RNA will further result for the formation of proteins.....
      If want to stop the protein synthesis so we will induce another RNA intentionally from outside... because of which RNA becomes double stranded and only single stranded RNA can form protein and now it is in double stranded form so there will be no protein synthesis....

  • @diksha4966
    @diksha4966 6 років тому +1

    Thanku so much😊

  • @karthikeyanvenugopal8074
    @karthikeyanvenugopal8074 4 роки тому

    What is transposon sir?

  • @tasleemshaik193
    @tasleemshaik193 4 роки тому +1

    Yeh joh cimplementary rna joh ki kisi virus k dwra laya jaata hy kya iska koi defect nhi hota???? I mean doesn't it harm any way????
    Sir I hope u will look into my doubt pllz

  • @Dev_Sisters
    @Dev_Sisters 4 роки тому +1

    Very nice vidio sir bhot easy way me samjhaya hai aapne or ncert ko cover kerne wala vidio hai thanx sir

  • @smaranikapadhi7280
    @smaranikapadhi7280 3 роки тому +2

    Mind-blowing explanation

  • @kpawar9234
    @kpawar9234 3 роки тому

    I like your explanation it's really helped me 😊

  • @darkwarrior1417
    @darkwarrior1417 3 роки тому +1

    Bhai ,
    What is the difference between ANTISENSE RNA TECHNIQUE AND RNAi

  • @PANKAJKUMAR-un9qt
    @PANKAJKUMAR-un9qt 6 років тому +2

    Thnxx sir....u r the best

  • @renusaini1283
    @renusaini1283 5 років тому +1

    Ty for a nice lecture 😚

  • @noyssam
    @noyssam 4 роки тому +2

    How complementary ds rna silence the ss rna?

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 роки тому +3

      Hey it reality its a lot more complex than this. The Ds RNA will then help form something called a Silencing complex with a couple of proteins. One of the strands act as a guide Strand while the other is degraded and this guide strand will search for a specefic recognition sequence of the Nematode mRNA and the silencing complex will then silence it. Heres a video where it explains RNAi. You dont need to know for exam though though. They wont ask about the RISC complex or Argonaught proteins. :)m.ua-cam.com/video/cK-OGB1_ELE/v-deo.html

  • @princearya412
    @princearya412 5 років тому +1

    It's really very helpful 👍

  • @SunitaDevi-vw9fe
    @SunitaDevi-vw9fe 4 роки тому +5

    Sir nice lecture but it is so time consuming

  • @amitheldobabu4579
    @amitheldobabu4579 2 роки тому +5

    Thankyou sir for such a dedication to class. It helps us to understand complex portions easily. We are very thankful to you sir🥰

  • @ektachhaila6958
    @ektachhaila6958 4 роки тому +2

    dsDNA bind hota h mMNA se??

  • @edwardcullen6886
    @edwardcullen6886 6 років тому +1

    Thank you sir

  • @aditisri8470
    @aditisri8470 4 роки тому +1

    loads of thank you sir

  • @shubhampaikrao3951
    @shubhampaikrao3951 4 роки тому +1

    Thanks brother 👍

  • @manjuagarwal4100
    @manjuagarwal4100 4 роки тому +16

    Outstanding.🤗🤗🤗🏅🥇🥇🏅🏅🥇🥇

  • @ashwiniashwini2110
    @ashwiniashwini2110 5 років тому +1

    befor watching the video only i will like it because i know it will be good

  • @shahnazbegum1463
    @shahnazbegum1463 5 років тому +2

    Thanks sir for coming back on screen 👍👍👍👍👍

  • @anandhuvijayan7027
    @anandhuvijayan7027 6 років тому +2

    you are a powerful teacher , KEEP IT UP thank u

  • @bharathfittness9183
    @bharathfittness9183 3 роки тому +1

    Best techer i ever sown..✨

  • @GurshaanGaming
    @GurshaanGaming 2 роки тому +2

    So main thing is that we silence specific mRNA of the nematode so that Translation could be denied.🤔
    Right?

  • @pawansoni5446
    @pawansoni5446 6 років тому +1

    You are the best biology teacher

  • @mahejabeen906
    @mahejabeen906 4 роки тому +1

    How we provide or from where we provide double strand rna

    • @jyotizine4047
      @jyotizine4047 4 роки тому

      Same doubt

    • @AtoofaHilal
      @AtoofaHilal 2 роки тому

      That may be frm any infection caused by virus having rna genome...since normally our body doesn't hv ds rna

  • @akashsandhu3846
    @akashsandhu3846 5 років тому +1

    Please make a video on BT cotton

  • @SOMVANSHI909
    @SOMVANSHI909 4 роки тому +1

    Thanks bro😊

  • @Asmitneetmedico
    @Asmitneetmedico 4 роки тому

    thank you very much Sir. ..it is very helpful

  • @ashishgadekar3260
    @ashishgadekar3260 6 років тому +3

    Sir u are the best... Sir after this lesson start ecology..

  • @adarshprasad177
    @adarshprasad177 5 років тому +3

    Now i take interest in biology too...thnqq sir your videos and explanation inspired me too study bio...with interest

  • @parulbajpai3721
    @parulbajpai3721 5 років тому +1

    You made it very easy sir tysm

  • @zoyokhan1844
    @zoyokhan1844 5 років тому +2

    Thanks a lot sir your help from all students

  • @jagdishsad7617
    @jagdishsad7617 3 роки тому +1

    Thanks bhaiya

  • @kaimsardarni2928
    @kaimsardarni2928 5 років тому

    will u plz guide me how to make notes of genetic (botany ) class 12

  • @madhurima3208
    @madhurima3208 5 років тому +16

    Please add some more information. Thank you for clearing my doubt 😃😃

  • @RahulSingh-dc8js
    @RahulSingh-dc8js 5 років тому +8

    Main part to samjh hi nahi aaya yaar!!!!

  • @surinderpal7125
    @surinderpal7125 5 років тому +11

    thanku so much sir for this video....i was little confused in this topic..but now all my doubts are cleared...again thanks to u....🙏😊😊

  • @priyajoshi5646
    @priyajoshi5646 2 роки тому

    ❤️ thanku sir..
    Some hr later I have my biology exam

  • @raghibakbar2821
    @raghibakbar2821 6 років тому +1

    Thnxx you so much sir

  • @its_vikram_07
    @its_vikram_07 5 років тому +1

    Excellent teaching sir......

  • @ajinkyatelgote3329
    @ajinkyatelgote3329 6 років тому +7

    sir, please discuss about transposons

  • @chandrabhushan3795
    @chandrabhushan3795 2 роки тому

    Thanks sir from bottom of my heart ❤️

  • @GunjanR516
    @GunjanR516 Рік тому

    God level teaching... Thank uh

  • @jyotipal7209
    @jyotipal7209 6 років тому +1

    thanks sir

  • @someshjaiswal6750
    @someshjaiswal6750 5 років тому +1

    amazing sir

  • @kuchipudigayathrirajasekha2456
    @kuchipudigayathrirajasekha2456 3 роки тому

    Thank you so much sir🙏👌

  • @melotingletales3257
    @melotingletales3257 5 років тому +1

    tons of thanks to you Bhaiya😇

  • @joytm6263
    @joytm6263 6 років тому +1

    thankyou

  • @sahilsingla771
    @sahilsingla771 4 роки тому

    Thnx Bhai ❤️

  • @ravibishnoiravibishnoi8191
    @ravibishnoiravibishnoi8191 4 роки тому +1

    Thanks sir 👍 👌

  • @lalamsandhya8433
    @lalamsandhya8433 6 років тому +1

    Tq so much sir

  • @akankshamishra12thb77
    @akankshamishra12thb77 9 місяців тому

    Jb complementary rna already double stranded hai toh wo nematode kai mrna se kyu bind kre ga .. nematode kai mrna toh free hai uske trna aa-aa kr protein chain bna denge ..

  • @vedantvaswani8823
    @vedantvaswani8823 2 роки тому

    Very well explained!

  • @jyotiray9858
    @jyotiray9858 5 років тому +2

    Sir is these enough for AIIMS?