Transportation of Oxygen : Respiratory physiology USMLE Step 1

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash
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Transportation of Oxygen : Respiratory physiology USMLE Step 1
Oxygen is transported from the lungs to the tissues by the circulatory system. The oxygen-rich blood from the lungs enters the left atrium, then flows into the left ventricle and is pumped out into the systemic circulation via the aorta. The oxygen is then taken up by hemoglobin, the protein found in red blood cells that binds oxygen, and is transported to the tissues.
There are several factors that affect the binding of oxygen to hemoglobin. One of the most important factors is the partial pressure of oxygen in the blood, commonly known as the PO2. As the PO2 increases, more oxygen binds to hemoglobin, and as the PO2 decreases, less oxygen binds to hemoglobin. This relationship is described by the oxygen-hemoglobin dissociation curve.
Another factor that affects the binding of oxygen to hemoglobin is the presence of other molecules in the blood, such as carbon monoxide (CO) and hydrogen ions (H+). CO binds to hemoglobin with a much higher affinity than oxygen, so even small amounts of CO in the blood can displace oxygen from hemoglobin and reduce oxygen transport. High levels of H+ in the blood, as seen in conditions such as acidosis, can also reduce the affinity of hemoglobin for oxygen and impair oxygen transport.
In addition to binding to hemoglobin, a small fraction of oxygen is dissolved in the plasma and transported in the blood. This dissolved oxygen is important because it can diffuse across cell membranes and directly enter the tissues, providing oxygen to areas with poor blood flow.
Overall, understanding the mechanisms of oxygen transport is critical to understanding respiratory physiology and preparing for the USMLE Step 1 exam.
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[@saqibsaeed4992]

Sir not carboxy haemoglobin it is carb aminohaemoglobin .carboxy haemoglobin is when haemoglobin bind with carbon mono oxide

[@vikrams-3954]

Love from tamil nadu

[@FitWithArpit]

very informative

[@maneswarbhatra3375]

Love from odisha

[@nsari-ll7kw]

Superb explanation ...do you teach medicine also...

[@doctorbhanuprakash]

Yes we do it from march 2nd week

[@vikaramvicky6025]

Sir bscmlt antomy physiology class kuda chepu sir

[@YLN786]

Super,, explanation brother.

[@doctorbhanuprakash]

Thanks and welcome

[@ravisai4555]

Thank you sir for this vedio

[@doctorbhanuprakash]

Most welcome.

[@mattaswathi2945]

Thank u so much for this video sir

[@doctorbhanuprakash]

Most welcome

[@sunitajayaramrao5108]

Thank you so much sir 🙏💐

[@doctorbhanuprakash]

So nice of you

[@k.kanikanik.kanikani4409]

Thank you sir 😊

[@doctorbhanuprakash]

Most welcome.

[@alanwaterman1328]

Very clearly explained. Thanks.

[@doctorbhanuprakash]

You are welcome!

[@SoumyaDeshwal]

❤❤

[@amolkelkar7231]

Nice video

[@doctorbhanuprakash]

Thanks

[@noorafaziludeen4199]

Bind blowing class sir

[@doctorbhanuprakash]

Many many thanks

[@Smrutiranjansha]

Best explanation ❤❤

[@doctorbhanuprakash]

Thanks a lot 😊

[@Knowledge_pedia528]

Sir the blood vessel carriyng deoxygenated blood to the lungs is pulmonary artery not veins ?????

[@ramubandari7437]

Yess

[@yeshwanthyesh4143]

Pulmonary artery

[@adeelnaeem2887]

wonderful explanation❤

[@doctorbhanuprakash]

Glad you liked it

[@user-eo4ry9qi7l]

I am an Arab and I cannot understand this doctor .......But his explanation seems very good❤🎉

[@amarjithsp5062]

Hb+Co2..... Carbamino hb???????

[@AbhishekKumarSingh-gv6rg]

yes,as it bonds with the amino chain of hb

[@spreadpositivity-mg4em]

11:10

[@muntazirnajir]

Why u r taking too much.. this is really irritating... You just tell us mechanism of oxygen simply

[@drkanaksingh1907]

CO2
70% bicarbonate
23% hemoglobin
7% dissolved plasma

[@MohdYunus--]

Yes 👍🏻