🌟 -- Rotary evaporator (How to use a Rotavap /Rotovap)

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  • Опубліковано 1 гру 2024

КОМЕНТАРІ • 83

  • @mitramikeextractz4502
    @mitramikeextractz4502 3 роки тому +4

    Great video thank you so .ugh for the teaching ,it has been many long years since I've used a rotovap and this was the best video I have seen to freshen up my brain to use one again,really grateful!

  • @muhammadfitobayubaskara7775
    @muhammadfitobayubaskara7775 3 роки тому +5

    "The beginning is always the hardest" well.. this is gonna be my first time and I hope it will doing well :) Thanks for the instructions!

  • @Sp-fe1eo
    @Sp-fe1eo 2 роки тому +1

    thanks for the video...it's really helped me a lot

  • @henryng439
    @henryng439 5 днів тому +1

    4:46 is it normal for the evaporating flask to be bouncing up and down on the water bath? mine does that too. the tube is not perfectly straight. do I need to buy a replacement tube?

    • @chemfunman
      @chemfunman  4 дні тому

      Not normal in my experience, need to check your setup connectivity

    • @henryng439
      @henryng439 4 дні тому

      @@chemfunman at 4:46 , your flask is also bouncing up and down. It will be more noticeable if you install a larger 2000ml flask.

  • @napbiyo7472
    @napbiyo7472 9 місяців тому +1

    hi thanks for the video! may I ask, can I use the liquid extract sample immediately for further analyses?

  • @lam4888
    @lam4888 Рік тому +1

    great video, thank you so much

  • @thelearner3962
    @thelearner3962 3 роки тому +3

    As always, great video!
    I have a question.
    When I used this in the lab first time, I remember my instructor told me there is a specific sequence of turning on/ off the vacuum tap and the aspirator. He told me the wrong order will spoil the aspirator.
    I remember: aspirator on, tap close, then after evaporation, tap open, aspirator close (as what you did).
    Does it really matter? If after evaporation I turn off the aspirator before opening the tap, how will that spoil the aspirator?
    Thank you :)

  • @z-boxwriter5004
    @z-boxwriter5004 3 роки тому +1

    If you want to install a vacuum controller (vacuum gauge) in this Aspirator, the 'Y' is needed or how you connect it?

    • @chemfunman
      @chemfunman  3 роки тому

      need to attach with a keck clip

  • @adityapatel8156
    @adityapatel8156 Рік тому +1

    Can we use a 10 ml round bottom flask with a connector ? it is because I have a very small volume of samples .samples are very costly.

    • @chemfunman
      @chemfunman  Рік тому

      Yes, it is possible, slow the rotation speed and do it carefully.

  • @Billy011
    @Billy011 3 роки тому +1

    I am doing ethanol cannabi extraction.
    Mainly trying to get around the steeep chiller and vacuum regulator prices.. any help appreciated 🙏

  • @movax20h
    @movax20h 4 роки тому +1

    Nice. Do you sometimes use an ice bath on the receiver flask? What about using higher vacuum? Afaik aspirator pump can't get really high vacuum, unless it is used with some oil instead of water. And how do you clean or replace the seals between moving and non-moving parts in the rotovap?

    • @chemfunman
      @chemfunman  4 роки тому +1

      I do use ice in my receiver sometimes.

  • @almche8978
    @almche8978 2 роки тому +1

    Thank you Dr. for this. I have question : after student finished his synthesis in lab some times have liquid waste , here can throw it with non halogenation solvents or in other container?
    Also, how about solid waste like precipitate , here under which name of container throw it? Thanks

    • @chemfunman
      @chemfunman  2 роки тому +1

      Should not mix them.

    • @chemfunman
      @chemfunman  2 роки тому +1

      Solid waste discard separately.

    • @almche8978
      @almche8978 2 роки тому +1

      @@chemfunman thank you

    • @almche8978
      @almche8978 2 роки тому +1

      @@chemfunman thank you

  • @z-boxwriter5004
    @z-boxwriter5004 3 роки тому +1

    When I use and Aspirator Pump similar to this, for some reason, the water of the tank of the pump goes through the hose to fall inside of the condenser and then to the receiver flask. Do you have a clue why this is happening? Help me, please

    • @chemfunman
      @chemfunman  3 роки тому

      the water? it should be a mix of alcohol and water

    • @z-boxwriter5004
      @z-boxwriter5004 3 роки тому

      @@chemfunman We use only water in the tank, the laboratory doesn't have budget for many things so I do my best in the Lab, but I see this problem and I don't understand what's going about the backflow of the water (common water i.e., a tank filled with running water from faucet)

  • @PepeRoldan1961
    @PepeRoldan1961 3 роки тому +1

    I noticed in the video the vacuum line is not hooked up. Can the rotary evaporator be used without vacuum? Also: How do you know that all the solvent is evaporated out of the liquid mixture? If the compound is resinous, do you leave some solvent and pour it into something else to let the rest of the solvent evaporate?

    • @chemfunman
      @chemfunman  3 роки тому +1

      If the vacuum is absent, it takes longer to evaporate certain solvents. Sometimes, this is even impossible. In my experiments I have used partial vacuum to control the drying process, because for volatile solvents, full vacuum may be too strong and sucks out all my products altogether.

    • @chemfunman
      @chemfunman  3 роки тому +1

      If the product is resinous, I recommend inserting a dry cotton wool at the neck of the glass joint, so that even if the vacuum pulls them into the condenser, the products are collected/ trapped at the cotton wool.

  • @shoaibahmed4746
    @shoaibahmed4746 2 роки тому +1

    How to operate SHZ-D(III) evaporator, please

  • @sabrinasin123
    @sabrinasin123 4 роки тому +2

    Thank you for your sharing, sir. This video really give me some ideas for my lab work. By the way, I have question with the solid / liquid form of sample. Is it because of the solvent that affect the formation of sample after evaporation?

    • @chemfunman
      @chemfunman  4 роки тому +2

      solubility of the solute in the solvent, so yes, when the solvent vaporized, the solid/ liquid will appear!

  • @rotavapuser
    @rotavapuser 7 років тому +4

    good video. I highly recommend the use of a vacuum controller or at least a bleeding valve to get a stable vacuum and not just full vacuum that would increase the loss of solvent to the environment.

    • @chemfunman
      @chemfunman  7 років тому +1

      agree with you! thank you for your support.

    • @Billy011
      @Billy011 3 роки тому

      What do i need to make a bleed valve to keep the vacume pressure stable?
      I can not afford those 1200$ digital regulators...
      Thank you

    • @rotavapuser3093
      @rotavapuser3093 3 роки тому

      @@Billy011 check this out : www.amazon.com/Buchi-047391-Manometer-Needle-Rotavapor/dp/B00BT3XDBK

  • @rainh2135
    @rainh2135 3 роки тому +1

    Im using rotary to evaporate methanol from my microalgae extract so i can get the compound. The sample was in liquid form , how long do i need to evaporate so i get the compound only without the solvent ?

    • @chemfunman
      @chemfunman  3 роки тому

      the boiling point of methanol is pretty high for a rotavap to dry - would you think the microalgae will 'decompose' ?

    • @rainh2135
      @rainh2135 3 роки тому

      @@chemfunman the microalgae cell already been soaked in methanol for 24 hours. We want the compound to be concentrated ? And by using the rotary i could reduce the amount using low temperature than methanol usual bp.

  • @surjitdeka7092
    @surjitdeka7092 3 роки тому

    Sir my sample is black pepper and I want to extract the piperine and then I will quantity it by HPLC..
    Can I extract it through rotary evaporator.
    Now my doubt is that if I put the grinding material plus solvent into the round bottom flux and after removing the sovant 100 percent, there will be lots of residue which will not be dissolved in methanol for HPLC.
    So what should I do
    I think I have to go first for sohxlet extraction then filter it and then have to go for rotary evaporator to remove solvant. M I right sir..

    • @chemfunman
      @chemfunman  3 роки тому

      To use a rotavap, your solute MUST dissolve in the solvent. If you have a suspension, it is unwise to use this method of drying...

    • @surjitdeka7092
      @surjitdeka7092 3 роки тому

      @@chemfunman but I found in a research paper after sohxlet extraction they carried out the rotavator to obtain the final extract. When I used rotavator I found a semi solid extract. And then I put the sample in lyophilizer.. but I m not getting the powder from of my extract
      How can I convert my plant extract into Powder form for hplc analysis

  • @noreenramzan6727
    @noreenramzan6727 4 роки тому +1

    thank u Sir for explanation ..
    Sir i want to know about error related to rotation and heating ... in my uni lab Heidolph rotary apparats avalible. have u any idea about error related to rotation and heating .plz Sir help me

  • @samihakabir812
    @samihakabir812 8 років тому +1

    So I made a fruit ethanol extract but I guess maybe I let the thing run for too long. Now the extract is completely stuck to the wall of the flask, it looks like melted plastic. Idk how to get it out and idk how I'm going to use it now. Please help!

    • @chemfunman
      @chemfunman  8 років тому

      add a solvent and warm, sonicate.

    • @Billy011
      @Billy011 3 роки тому

      A heat gun and a clamp to hold it up to drip..
      Did you get it out?

  • @markopoloasia
    @markopoloasia 4 роки тому +1

    Nice vid!

    • @chemfunman
      @chemfunman  2 роки тому

      thank you! please give us a like and share. Bless you.

  • @noreenramzan6727
    @noreenramzan6727 4 роки тому +1

    by Heidolph Rotary after setting the rotation and temperature ... rotary dnt start and show error below the rotation digits.. how to remove error .

    • @noreenramzan6727
      @noreenramzan6727 4 роки тому

      plz suggest me how to fix error ..😟

    • @chemfunman
      @chemfunman  4 роки тому

      hmm.. any photos?

    • @noreenramzan6727
      @noreenramzan6727 4 роки тому

      @@chemfunman i will make photo tomorrow but at that time i dnt have any... Sir could u tell me your email

  • @angelbenazir9122
    @angelbenazir9122 7 років тому +2

    and if the extracts are stuck to the wall of the round bottom flask!!! How can i remove the extract??
    Thank You
    MPhil Student

    • @chemfunman
      @chemfunman  7 років тому

      use a spatula and scratch

    • @angelbenazir9122
      @angelbenazir9122 7 років тому

      Will it be good if i use about 10 ml of the solvent to re suspend the extract??
      Your opinion would be very much appreciated.
      Thank You

    • @chemfunman
      @chemfunman  7 років тому +1

      sounds ok, depending on the size of RBF

    • @balasinghammayooran7195
      @balasinghammayooran7195 6 років тому

      You can washed with easily evaporated solvent such as diethylether then use funnel and vacuum to get solid results.

    • @acez_up8104
      @acez_up8104 5 років тому

      heat gun

  • @From_the_city_of_Queen_Jhansi
    @From_the_city_of_Queen_Jhansi 5 років тому +1

    Well explained...
    should I use Methanol and Water in Chiller ?

  • @fakhrulnawawi9681
    @fakhrulnawawi9681 3 роки тому +1

    Mantap

  • @ravinaik5385
    @ravinaik5385 7 років тому +1

    very nice video

  • @ezequielsanchez9822
    @ezequielsanchez9822 7 років тому +1

    Hola, ¿cuanto tiempo aproximado se tarda en destilar aceites?,gracias

    • @chemfunman
      @chemfunman  7 років тому

      Si Si, hablas Ingles, amigo? How long ... ?

    • @ezequielsanchez9822
      @ezequielsanchez9822 7 років тому

      yes, How long approximately it takes distill one substance,for example water with Orange peels?because i think buy equipment Similar to this. thank you.

    • @chemfunman
      @chemfunman  7 років тому

      I would not use the rotary evaporator to distill orange oil from the peels... will use steam distillation --> it is in my other video. have a look.

  • @mihaipopa9414
    @mihaipopa9414 5 років тому +2

    Thanks for close caption. Voice a bit hard to understand...

    • @Andrew-my1cp
      @Andrew-my1cp 4 роки тому +1

      Really? Interesting I had no problem understanding his accent. He did speak pretty quietly though.

    • @mihaipopa9414
      @mihaipopa9414 4 роки тому +1

      @@Andrew-my1cp That's what I meant, sorry. I removed the inconsiderate word.

    • @Andrew-my1cp
      @Andrew-my1cp 4 роки тому +2

      @@mihaipopa9414 Oh okay haha. I was just wondering since I hear a lot of accents (some stronger than othere) if I maybe just got better at understanding them over time. It's all good though.

  • @kusalsilva-qt9ej
    @kusalsilva-qt9ej 2 роки тому

    Use fume hood