🌟 -- Rotary evaporator (How to use a Rotavap /Rotovap)
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- Опубліковано 7 сер 2024
- #Rotary #Rotaryevaporator #Rotovap
Rotary Evaporator is used to remove high boiling solvents under low pressure. Here is a demonstration on how to use rotary evaporator at the National University of Singapore.
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Great video thank you so .ugh for the teaching ,it has been many long years since I've used a rotovap and this was the best video I have seen to freshen up my brain to use one again,really grateful!
Glad it was helpful!
very nice video
Mantap
"The beginning is always the hardest" well.. this is gonna be my first time and I hope it will doing well :) Thanks for the instructions!
Glad it was helpful!
great video, thank you so much
You are welcome!
Nice vid!
thank you! please give us a like and share. Bless you.
thanks for the video...it's really helped me a lot
Glad to hear that
I am doing ethanol cannabi extraction.
Mainly trying to get around the steeep chiller and vacuum regulator prices.. any help appreciated 🙏
Thank you for your sharing, sir. This video really give me some ideas for my lab work. By the way, I have question with the solid / liquid form of sample. Is it because of the solvent that affect the formation of sample after evaporation?
solubility of the solute in the solvent, so yes, when the solvent vaporized, the solid/ liquid will appear!
good video. I highly recommend the use of a vacuum controller or at least a bleeding valve to get a stable vacuum and not just full vacuum that would increase the loss of solvent to the environment.
agree with you! thank you for your support.
What do i need to make a bleed valve to keep the vacume pressure stable?
I can not afford those 1200$ digital regulators...
Thank you
@@Billy011 check this out : www.amazon.com/Buchi-047391-Manometer-Needle-Rotavapor/dp/B00BT3XDBK
Nice. Do you sometimes use an ice bath on the receiver flask? What about using higher vacuum? Afaik aspirator pump can't get really high vacuum, unless it is used with some oil instead of water. And how do you clean or replace the seals between moving and non-moving parts in the rotovap?
I do use ice in my receiver sometimes.
As always, great video!
I have a question.
When I used this in the lab first time, I remember my instructor told me there is a specific sequence of turning on/ off the vacuum tap and the aspirator. He told me the wrong order will spoil the aspirator.
I remember: aspirator on, tap close, then after evaporation, tap open, aspirator close (as what you did).
Does it really matter? If after evaporation I turn off the aspirator before opening the tap, how will that spoil the aspirator?
Thank you :)
that works fine as well!
@@chemfunman leq
@@jovicic43 lag
hi thanks for the video! may I ask, can I use the liquid extract sample immediately for further analyses?
Yes
If you want to install a vacuum controller (vacuum gauge) in this Aspirator, the 'Y' is needed or how you connect it?
need to attach with a keck clip
thank u Sir for explanation ..
Sir i want to know about error related to rotation and heating ... in my uni lab Heidolph rotary apparats avalible. have u any idea about error related to rotation and heating .plz Sir help me
Already uploaded
Can we use a 10 ml round bottom flask with a connector ? it is because I have a very small volume of samples .samples are very costly.
Yes, it is possible, slow the rotation speed and do it carefully.
Hola, ¿cuanto tiempo aproximado se tarda en destilar aceites?,gracias
Si Si, hablas Ingles, amigo? How long ... ?
yes, How long approximately it takes distill one substance,for example water with Orange peels?because i think buy equipment Similar to this. thank you.
I would not use the rotary evaporator to distill orange oil from the peels... will use steam distillation --> it is in my other video. have a look.
Im using rotary to evaporate methanol from my microalgae extract so i can get the compound. The sample was in liquid form , how long do i need to evaporate so i get the compound only without the solvent ?
the boiling point of methanol is pretty high for a rotavap to dry - would you think the microalgae will 'decompose' ?
@@chemfunman the microalgae cell already been soaked in methanol for 24 hours. We want the compound to be concentrated ? And by using the rotary i could reduce the amount using low temperature than methanol usual bp.
Well explained...
should I use Methanol and Water in Chiller ?
water
isopropanol + water
what ratio I used to fill the chiller.?
So I made a fruit ethanol extract but I guess maybe I let the thing run for too long. Now the extract is completely stuck to the wall of the flask, it looks like melted plastic. Idk how to get it out and idk how I'm going to use it now. Please help!
add a solvent and warm, sonicate.
A heat gun and a clamp to hold it up to drip..
Did you get it out?
Thank you Dr. for this. I have question : after student finished his synthesis in lab some times have liquid waste , here can throw it with non halogenation solvents or in other container?
Also, how about solid waste like precipitate , here under which name of container throw it? Thanks
Should not mix them.
Solid waste discard separately.
@@chemfunman thank you
@@chemfunman thank you
I noticed in the video the vacuum line is not hooked up. Can the rotary evaporator be used without vacuum? Also: How do you know that all the solvent is evaporated out of the liquid mixture? If the compound is resinous, do you leave some solvent and pour it into something else to let the rest of the solvent evaporate?
If the vacuum is absent, it takes longer to evaporate certain solvents. Sometimes, this is even impossible. In my experiments I have used partial vacuum to control the drying process, because for volatile solvents, full vacuum may be too strong and sucks out all my products altogether.
If the product is resinous, I recommend inserting a dry cotton wool at the neck of the glass joint, so that even if the vacuum pulls them into the condenser, the products are collected/ trapped at the cotton wool.
When I use and Aspirator Pump similar to this, for some reason, the water of the tank of the pump goes through the hose to fall inside of the condenser and then to the receiver flask. Do you have a clue why this is happening? Help me, please
the water? it should be a mix of alcohol and water
@@chemfunman We use only water in the tank, the laboratory doesn't have budget for many things so I do my best in the Lab, but I see this problem and I don't understand what's going about the backflow of the water (common water i.e., a tank filled with running water from faucet)
How to operate SHZ-D(III) evaporator, please
How long you bought it?
Sir my sample is black pepper and I want to extract the piperine and then I will quantity it by HPLC..
Can I extract it through rotary evaporator.
Now my doubt is that if I put the grinding material plus solvent into the round bottom flux and after removing the sovant 100 percent, there will be lots of residue which will not be dissolved in methanol for HPLC.
So what should I do
I think I have to go first for sohxlet extraction then filter it and then have to go for rotary evaporator to remove solvant. M I right sir..
To use a rotavap, your solute MUST dissolve in the solvent. If you have a suspension, it is unwise to use this method of drying...
@@chemfunman but I found in a research paper after sohxlet extraction they carried out the rotavator to obtain the final extract. When I used rotavator I found a semi solid extract. And then I put the sample in lyophilizer.. but I m not getting the powder from of my extract
How can I convert my plant extract into Powder form for hplc analysis
and if the extracts are stuck to the wall of the round bottom flask!!! How can i remove the extract??
Thank You
MPhil Student
use a spatula and scratch
Will it be good if i use about 10 ml of the solvent to re suspend the extract??
Your opinion would be very much appreciated.
Thank You
sounds ok, depending on the size of RBF
You can washed with easily evaporated solvent such as diethylether then use funnel and vacuum to get solid results.
heat gun
by Heidolph Rotary after setting the rotation and temperature ... rotary dnt start and show error below the rotation digits.. how to remove error .
plz suggest me how to fix error ..😟
hmm.. any photos?
@@chemfunman i will make photo tomorrow but at that time i dnt have any... Sir could u tell me your email
Use fume hood
Yes
Thanks for close caption. Voice a bit hard to understand...
Really? Interesting I had no problem understanding his accent. He did speak pretty quietly though.
@@Andrew-my1cp That's what I meant, sorry. I removed the inconsiderate word.
@@mihaipopa9414 Oh okay haha. I was just wondering since I hear a lot of accents (some stronger than othere) if I maybe just got better at understanding them over time. It's all good though.