A practical guide on how to calculate AUC from pharmacokinetic data. Learn more by registering for my course on noncompartmental analysis at www.udemy.com/noncompartmenta...
This is a very good tutorial. However, for the ln C1 - ln C2, the values are not reproducible. Here the equation, AUC = (C1-C2)/(ln C1-C2) x time difference. I actually got the final AUC values exactly to this video. We take 48 hours as example. C1-C2 = 4.269-1.286=2.983 ln C1-lnC2 = ln4.269 - ln1.286 = 1.199 Use the equation, 2.983/1.199 x 12 = 29.83, exactly similar to the value above. p.s.: the values I shown just to demostrate how to calculate.
i am unable to reproduce your math for the lnC1-lnC2 calculation. how exactly are you doing this? natural log (C1) - natural log (C2) or natural log (C1-C2)....
This is a very good tutorial. However, for the ln C1 - ln C2, the values are not reproducible. Here the equation,
AUC = (C1-C2)/(ln C1-C2) x time difference. I actually got the final AUC values exactly to this video.
We take 48 hours as example.
C1-C2 = 4.269-1.286=2.983
ln C1-lnC2 = ln4.269 - ln1.286 = 1.199
Use the equation, 2.983/1.199 x 12 = 29.83, exactly similar to the value above.
p.s.: the values I shown just to demostrate how to calculate.
Thank you! This really helped me!
Thank you so much! This helped me out a lot!
great video!
Hey, Great video! i was wondering if you knew if this could be applied to other types of data, other than drug concentrations?
i am unable to reproduce your math for the lnC1-lnC2 calculation. how exactly are you doing this? natural log (C1) - natural log (C2) or natural log (C1-C2)....
i cant seem to reproduce the math on lnC1-lnC2. how exactly is this being calculated?
values of AUC-linear is not right 1.64/50.26 x 1 is not equal to 82.76..how is it calculated??
Can you calculate total drug release in nanograms from the concentration/time curve?
what is the AUC linear? please help me
thanks you very much
THANKyou
great video!