RNA-based Drugs Including Delivery of Antibodies and Vaccines Using mRNA

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  • Опубліковано 14 жов 2024

КОМЕНТАРІ • 16

  • @hollya.g.86
    @hollya.g.86 4 роки тому +10

    conflicts of interest slide was there for almost exactly 1 second

  • @jwang6954
    @jwang6954 3 роки тому

    I wish they brought in Dr. Kariko-the real brains behind the research!

  • @MrEthanhines
    @MrEthanhines 4 роки тому +2

    So begs the question: can you slap on a corona virus spike mrna into an LNP and get a human antigen response?

    • @yaredarcher3774
      @yaredarcher3774 3 роки тому

      This aged well!!! Wonder if they saw your comment😭😭

    • @voidisyinyangvoidisyinyang885
      @voidisyinyangvoidisyinyang885 3 роки тому +3

      the irony being that Ginger is proven to block the ACE2 receptor also - mimicking the S protein. But you can't patent Ginger. I even uploaded a vid on this but it was censored.

    • @ixtlimrtnz
      @ixtlimrtnz 3 роки тому

      @@voidisyinyangvoidisyinyang885 could you explain this to me?

    • @voidisyinyangvoidisyinyang885
      @voidisyinyangvoidisyinyang885 3 роки тому +3

      @@ixtlimrtnz It is also interesting that theaflavin 3,3'-digallate, a
      phenolic compound present in ginger, was found to interact both with ACE2 receptor...with considerable biding affinities. Our present
      finding of theaflavin 3,3'-digallate and previous results regarding to phenolics as hits
      (8) prompted us to consider their effects against SARS-CoV-2 might be also
      associated with their antioxidant potency. With this rationale, we tentatively suggest
      that marketed antioxidants such as edaravone and intake of ginger with high content
      of phenolics might be beneficial for SARS-CoV-2 patients. Unfortunately, this
      hypothesis and therapeutic approach has been largely ignored during SARS-CoV-2
      outbreak.
      Discovery of anti-SARS-CoV-2 agents from commercially available
      flavor via docking screening
      Jiao-Jiao Zhang1,†, Xin Shen2,†, Yong-Ming Yan1, Yan Wang2,*, Yong-Xian Cheng1,*
      1 School of Pharmaceutical Sciences, Shenzhen University Health Science Center,
      Shenzhen 518060, P.R. China
      2 Center for Translation Medicine Research and Development, Shenzhen Institute of
      Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P.R. China
      pdf link
      files.osf.io/v1/resources/vjch2/providers/osfstorage/5e5c9a92ef5d8902270697ea?action=download&direct&version=1

    • @ixtlimrtnz
      @ixtlimrtnz 3 роки тому

      @@voidisyinyangvoidisyinyang885 thank you so much. I’m going to check that out

  • @erezd8252
    @erezd8252 4 роки тому +1

    amazing