260 ‒ Men’s Sexual Health: why it matters, what can go wrong, and how to fix it

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  • Опубліковано 31 тра 2024
  • Full episode and show notes: bit.ly/3Pu6LL0
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    Mohit Khera is a urologist with expertise in sexual medicine. In this episode, he provides an overview of male sexual health. He first goes in-depth on erectile dysfunction, shedding light on its prevalence across different age groups, diagnostic methods, and its intriguing connection to cardiovascular disease. He then ventures into Peyronie's disease, penile fractures, penile enlargement treatments, prolonged erections, premature ejaculation, and anorgasmia. Mohit then delves into the intricate workings of testosterone, DHT, and estrogen, emphasizing their physiological significance and interplay. He explains blood tests for diagnosing low T, the correlation between symptoms and blood levels in cases of low T, and the various methods for increasing testosterone. He concludes with a conversation about the role of testosterone in patients with prostate cancer and addresses concerns surrounding DHT, finasteride, and post-finasteride syndrome.
    We discuss:
    0:00:00 - Intro
    0:01:18 - Mohit’s career path and interest in sexual medicine
    0:03:25 - The anatomy of the male genitalia
    0:05:06 - The prevalence of sexual dysfunction & impact on quality of life
    0:08:58 - Erectile dysfunction (ED): definition, diagnosis, pathophysiology
    0:13:41 - The history of medications to treat ED and the mechanisms of how they work
    0:18:21 - Relationship between aging & erectile dysfunction and Mohit's approach to treating patients
    0:29:14 - The impact of lifestyle on sexual health & the association between ED and cardiovascular disease
    0:37:52 - Causes and treatments for Peyronie’s Disease & penile fracture
    0:48:32 - The value of ultrasound for ED diagnosis and management strategies
    0:51:55 - Various treatment options for ED: injections, penile prosthesis
    0:59:38 - Priapism (prolonged erection)
    1:05:40 - Shockwave therapy as a treatment for ED
    1:11:46 - Stem cell therapy for ED
    1:15:48 - Platelet-rich plasma (PRP) injections as a treatment for ED
    1:18:36 - Premature ejaculation (PE): prevalence, pathophysiology, and treatment
    1:26:34 - Anorgasmia: causes and treatment
    1:31:52 - Sex hormones, impact of aging, symptoms of low T, & considerations for testosterone replacement therapy (TRT)
    1:44:49 - Methods for increasing endogenous testosterone
    2:00:03 - Testosterone replacement therapy: various forms of exogenous testosterone & weighing risk vs. reward
    2:11:03 - The physiology and purpose of testosterone and DHT, why some men feel fine even with “low” testosterone, personalized approaches to treating low T
    2:18:25 - Post-finasteride syndrome
    2:26:42 - The role of testosterone in prostate cancer and addressing the notion that TRT could increase risk
    2:38:29 - The effects of testosterone as an adjunct to therapy for estrogen-sensitive breast cancer in women
    2:40:08 - Resources for those looking for healthcare providers
    -
    About:
    The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health & more.
    Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
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  • Наука та технологія

КОМЕНТАРІ • 401

  • @PeterAttiaMD
    @PeterAttiaMD  11 місяців тому +40

    In this episode, we discuss:
    0:01:18 - Mohit’s career path and interest in sexual medicine
    0:03:25 - The anatomy of the male genitalia
    0:05:06 - The prevalence of sexual dysfunction & impact on quality of life
    0:08:58 - Erectile dysfunction (ED): definition, diagnosis, pathophysiology
    0:13:41 - The history of medications to treat ED and the mechanisms of how they work
    0:18:21 - Relationship between aging & erectile dysfunction and Mohit's approach to treating patients
    0:29:14 - The impact of lifestyle on sexual health & the association between ED and cardiovascular disease
    0:37:52 - Causes and treatments for Peyronie’s Disease & penile fracture
    0:48:32 - The value of ultrasound for ED diagnosis and management strategies
    0:51:55 - Various treatment options for ED: injections, penile prosthesis
    0:59:38 - Priapism (prolonged erection)
    1:05:40 - Shockwave therapy as a treatment for ED
    1:11:46 - Stem cell therapy for ED
    1:15:48 - Platelet-rich plasma (PRP) injections as a treatment for ED
    1:18:36 - Premature ejaculation (PE): prevalence, pathophysiology, and treatment
    1:26:34 - Anorgasmia: causes and treatment
    1:31:52 - Sex hormones, impact of aging, symptoms of low T, & considerations for testosterone replacement therapy (TRT)
    1:44:49 - Methods for increasing endogenous testosterone
    2:00:03 - Testosterone replacement therapy: various forms of exogenous testosterone & weighing risk vs. reward
    2:11:03 - The physiology and purpose of testosterone and DHT, why some men feel fine even with “low” testosterone, personalized approaches to treating low T
    2:18:25 - Post-finasteride syndrome
    2:26:42 - The role of testosterone in prostate cancer and addressing the notion that TRT could increase risk
    2:38:29 - The effects of testosterone as an adjunct to therapy for estrogen-sensitive breast cancer in women
    2:40:08 - Resources for those looking for healthcare providers

    • @RikimaruNobunaga
      @RikimaruNobunaga 11 місяців тому +2

      Terrible terrible advice to take a neuro toxic SSRI everyday for erectile disfunction. Truly unbelievable. SSRIs are clearly toxic to the human body and should not be prescribed like they are. Please Peter.

    • @TECHNOSINNER.
      @TECHNOSINNER. 11 місяців тому +7

      Antidepressants have caused me permanent damages

    • @DEricKuhn
      @DEricKuhn 11 місяців тому

      .

    • @FedeArgentina
      @FedeArgentina 10 місяців тому

      PERSONAL CONSULTATION:
      30 years old,
      I can have an erection, I can have sex without problems,
      But if we 'change position' or stop for only 10... 15 or 20 seconds... My erection is gone (+50% of the time), and I have to get exited again.
      Do I suffer ED?
      Or it's just in my mind? ... My theory all this time is that if I focus on talking about something else, whether it's answering a question like "what was that noise?" or stop the relationship and a phone starts ringing, then there is no sex for 10/20 seconds... I have no idea if losing an erection in those cases is normal for all men

    • @rickc6264
      @rickc6264 5 місяців тому

      Can

  • @HARRYSANDHUTEAMBOSS
    @HARRYSANDHUTEAMBOSS 8 місяців тому +18

    You conduct the best interviews - you let them speak - you interject for the viewer clarity - you ask the right questions - you rarely miss any key points.
    Master of your craft, Pete.
    Thank you

  • @afkVahn
    @afkVahn 11 місяців тому +107

    Post-Finasteride Syndrome (PFS) has utterly destroyed my life. I suffer from genital numbing, penile tissue deformations and shrinkage, zero libido/arousal, ED and other physical symptoms. This has been going on for a years and it’s driving me to suicide because no one is taking it seriously and the suffering is inhumane. Please doctors, I don’t want to be another statistic in this. Help us with raising more awareness, funds and research. It’s so badly needed for all the people who are suffering from this horrific disease.

    • @JCPProductions01
      @JCPProductions01 11 місяців тому +8

      I'm sorry to hear that. I wonder if anabolic/ androgenic steroids would help. For example, high test or trenbolone for the very high libido and drive side effect

    • @Abdullah-mt9ns
      @Abdullah-mt9ns 11 місяців тому +13

      It is way more common than people think

    • @afkVahn
      @afkVahn 11 місяців тому +7

      @@JCPProductions01 no, it’s been tried. People with PFS don’t respond (correctly) to high doses of test or any steroid for that matter. Imagine that.

    • @JCPProductions01
      @JCPProductions01 11 місяців тому +2

      @afkVahn thank you! I was definitely curious

    • @cupofmozzarella
      @cupofmozzarella 11 місяців тому +4

      You think you have other issues because finasteride nowhere near as invasive as you proclaim it to be.

  • @christykirkendolwatsonm.d.3419
    @christykirkendolwatsonm.d.3419 11 місяців тому +26

    As a physician in the TRT/HRT world this was phenomenal and changed my practice! SOOOO much information. Keep more like this coming!

    • @ronmexico79
      @ronmexico79 9 місяців тому +2

      Hello, I'm currently looking for trt/hrt treatment, but I don't know where to begin. Can you help??

    • @christykirkendolwatsonm.d.3419
      @christykirkendolwatsonm.d.3419 9 місяців тому +1

      @@ronmexico79 yes absolutely. Where do you live?

    • @ronmexico79
      @ronmexico79 9 місяців тому

      @@christykirkendolwatsonm.d.3419 wilmington delaware

  • @AC-ns4gu
    @AC-ns4gu 11 місяців тому +47

    Thank you so much Dr. Khera and Dr. Attia for shedding light on Post Finasteride Syndrome (PFS). This condition is devastating and we badly need support. I am a 27 year old man who has been suffering for 4 years and my life has been totally destroyed. I am broken neurologically, physically and sexually.
    I’ve spoken to countless men all over the world who are being subjected to inhumane torture as a result of finasteride. I’ve even had a good friend take their own life because of PFS.

    • @patrickr9931
      @patrickr9931 11 місяців тому +1

      Was that Marc?

    • @AC-ns4gu
      @AC-ns4gu 11 місяців тому +1

      @@patrickr9931 yes it was

    • @ballislife9924
      @ballislife9924 11 місяців тому +8

      This podcast raises suspicion to the validity of PFS. I don't understand how you can be happy with this video as it basically denies the possibility of PFS if you really understand what these two are talking about.

    • @TheLocalDank
      @TheLocalDank 10 місяців тому +5

      @@ballislife9924-Kevin Mann cult member

    • @patrickr9931
      @patrickr9931 10 місяців тому

      @@ballislife9924 shut commerce gimo

  • @charleneshaver7146
    @charleneshaver7146 10 місяців тому +25

    As the wife of someone who has recently developed Ed, this is gold! It was a great way to help my husband. He watched the podcast, and it is helping guide us through the interventions with his urologist. We never would have known where to look for help! Dr Khera explains everything is such a calm reassuring way, that it really put my husband at ease. He had talked to the NP at our PCP's office, who presented all the options in a much scarier way, not intention, I'm sure but my husband was convinced, "I'm getting old, this happens to everyone and why bother." Such a same bc we've always had a healthy robust sexual relationship, and now bc of this information, there is hope. Thank you both Dr Attia and Dr Khera.

    • @slong8602
      @slong8602 2 місяці тому

      I'm on a gel and run a consistent 1200 test. After the last 3 years of the Covid jab there's no way I trust Big Pharm. I'm sure they will be adding MRNA if not already..No thanks

  • @rethinktestosterone
    @rethinktestosterone 11 місяців тому +40

    More conversations like this are needed! Well done Dr. Khera and Dr. Attia!

  • @allisa-vi7lp
    @allisa-vi7lp 8 місяців тому +10

    Please help these young men (and old) who are suffering from PFS (Post Finasteroid Syndrome). It is so tragic and life changing. It reminds me of damage that can result from benzo withdrawal. Please please use your platform to shed light on this. (Oh just saw you discussed this later in the broadcast, but more is needed)

    • @Yiahi65
      @Yiahi65 7 місяців тому

      You’re too kind

  • @Redjamm90
    @Redjamm90 11 місяців тому +11

    Wish they had also talked about PSSD, SSRI have caused me sexual dysfunction. Ruined my life.

  • @deepak70413
    @deepak70413 11 місяців тому +11

    What about post SSRI Sexual dysfunction (PSSD). Many ppl are suffering from it. Please spread the awareness

    • @cartertodd6061
      @cartertodd6061 11 місяців тому

      exactly what i was gonna say !!! he has no problem giving those out lol

  • @lowestprime
    @lowestprime 11 місяців тому +49

    Love that Peter is aware of PFS @2:18:00. Would be amazing to have a finasteride/PFS specific episode with a prominent researcher.

    • @cupofmozzarella
      @cupofmozzarella 11 місяців тому +4

      An episode about PFS with facts? Good luck with that!

    • @ayan0834
      @ayan0834 11 місяців тому +11

      Great point. I would also be fascinated to hear similar discussions on the effects of SSRIs on sexual health (even after cessation) from experts in both mental health and sexual health, and revisit whether as a society, we are grossly overusing these drugs without adequate respect towards potentially life-changing adverse outcomes.

    • @ethanbaggoo1513
      @ethanbaggoo1513 11 місяців тому +5

      ​@@ayan0834I would like to see this as well

    • @JZGreengo
      @JZGreengo 11 місяців тому +8

      With PSSD I’m stoked it was mentioned, thank god people are speaking up about Post Finasteride Syndrome, the awareness sufferers are doing must be working 💪🏻

    • @patrickr9931
      @patrickr9931 11 місяців тому +1

      Should I off myself extreme pfs at forty six

  • @randallsample1005
    @randallsample1005 11 місяців тому +16

    Oh, man, the parts of this discussion regarding prostate cancer really hit home. I was diagnosed with a high grade, high volume prostate cancer and underwent a radical prostatectomy about a year and a half ago, at the age of 62 (relatively young for this to happen, and in otherwise very good health). Dr. Attia is absolutely right in his recommendation of surgery. For me, the decision was a no-brainer, very clear. Nonetheless, there is the possibility of biochemical recurrence. If that were to happen, I'd really hope that the principles of the Transformer Trial have become more well known and applied! Excellent episode.

    • @nickstrapko7549
      @nickstrapko7549 7 місяців тому +1

      Glad youre doing good. Im about to do a mri and bone scan for my cancer

  • @poostenbrug3053
    @poostenbrug3053 7 місяців тому +3

    Thank you for shining light on PFS and all your hard work doctor. I myself have PFS and have been suffering for 7 years. Started when i was 22 after only 5 months of finasteride. 0 libido and 0 erections. I was always healthy and exercised a lot. I've started TRT a year ago as a hail mary but still no effect on erections and libido.

  • @ethanbaggoo1513
    @ethanbaggoo1513 11 місяців тому +16

    Thanks for putting a spotlight on pfs - many of us sufferers appreciate it greatly

    • @anneboyer6359
      @anneboyer6359 11 місяців тому +1

      Please seek help with proper doctors and rule out other issues too. Mohit Khera is funded by the post finasteride foundation. Go look up his studies.

    • @Kalley_Kavia
      @Kalley_Kavia 10 місяців тому +7

      ​@@anneboyer6359And why do you think that is? Because sufferers of this condition are desperate to find answers. If the medical community took this seriously from the beginning more people wouldn't get their lives destroyed by a cosmetic "medication".

    • @ethanbaggoo1513
      @ethanbaggoo1513 10 місяців тому

      ​@anneboyer6359 Are you serious man? You do realize us sufferers regularly donate to the damn foundation because we have pfs. This condition only arose once I took finasteride, it is most certainly that damn drug that gave me these enduring side effects. Get educated.

  • @garyyencich4511
    @garyyencich4511 11 місяців тому +29

    Great episode. Your video setup is always top notch but Dr Khera speaks so clearly and concisely and having him on-site took it to yet another level. The interplay between the various hormones and drug treatments coupled with individual situation is so complex it’s mostly beyond the ability of the average patient to make sense of. Even if that was the only thing I took away from this podcast it still would have been totally worthwhile. No one else is doing these kind of discussions at this at this level. Bravo!

  • @mickcunningham7786
    @mickcunningham7786 29 днів тому +1

    Absolutely loved this one. Please do a follow-up episode.

  • @aaronbailey9454
    @aaronbailey9454 11 місяців тому +9

    Good grief Peter let the guy finish one thought lol. There were a few times there where I really wanted to hear the rest of what he was saying.

  • @kentwright5346
    @kentwright5346 8 місяців тому +5

    Dr.Attia, This is an excellent lesson that is absolutely a residency-level lecture for any physician who treats men. Many thanks for your work!

  • @petermartff
    @petermartff 11 місяців тому +7

    Dr. khera is great at explaining this topic. Very knowldgable and communicative. Great questions by Dr Attia

  • @aaronbailey9454
    @aaronbailey9454 11 місяців тому +42

    Ok, this is really crazy. In 2017, at age 35 I started having ED issues. 2 years later I had a massive heart attack. This podcast should’ve happened 6 years ago! 😆

    • @ballislife9924
      @ballislife9924 11 місяців тому +2

      This podcast raises suspicion to validity of PFS if anything

    • @bardsamok9221
      @bardsamok9221 10 місяців тому +2

      ​@@ballislife9924Arron's comment has nothing to do with "PFS". Did you even watch the podcast or just the PFS section as you suggested before?

    • @bardsamok9221
      @bardsamok9221 10 місяців тому +4

      Absolutely! Much respect to the candour of this discussion. The description connection between sexual and heart health is eye opening! Perfect two people to discuss it so clearly at a high level. Best of luck.

    • @ballislife9924
      @ballislife9924 10 місяців тому +2

      @bardsamok9221 Yes, my bad. Didn't read carefully enough.

    • @aaronbailey9454
      @aaronbailey9454 10 місяців тому

      @@ryu_street_fighter561 not really

  • @monroetinker9844
    @monroetinker9844 11 місяців тому +14

    Great episode thank you for this information. I worked primary care as an NP for over six years and I can't tell you that males have an extremely difficult time talking about sexual issues in general. Just getting patients into the office to control diabetes and hypertension let alone a annual physical is a challenge itself. Ty Dr. Attia.

    • @monroetinker9844
      @monroetinker9844 11 місяців тому

      Dr. Attia, Is it possible to send me a link where I can purchase a lactate monitor that you discussed in your zone 2 to training? It would be greatly appreciated. I am a fitness enthusiast.

  • @MXF11
    @MXF11 11 місяців тому +7

    Cialis is the best drug for BPH, too! I tried the others. Horrible side-effects! Cialis also makes me very vascular!

  • @eliteboxfitness
    @eliteboxfitness 11 місяців тому +4

    Thanks for this conversation drs. Learned a lot .
    Can't take anything for granted.

  • @supermellow1
    @supermellow1 9 місяців тому +3

    This is one of the best, most informative podcasts I’ve ever heard.

  • @sirdwayne8504
    @sirdwayne8504 11 місяців тому +1

    Have the Dr. On again. So informative and so eloquent. Awesome Dr. Attia. Thank you.

  • @HoraceFoca
    @HoraceFoca 10 місяців тому +2

    Such a magnificent discussion, thank you for making it available for us Peter

  • @user-cc5ij3co6e
    @user-cc5ij3co6e 9 місяців тому +3

    Fantastic conversation - its missing and needed! For clinicians also!!! I hope Dr. Khera is teaching therapists and other health professionals.

  • @skmrgoo5717
    @skmrgoo5717 11 місяців тому +8

    What I was disappointed about is that you didn’t ask him what is known about the risk of using a PDE-5 inhibitor such as Cialis long term. Some interesting melanoma papers have surfaced throughout the years and I think that he needed to give his take on them
    Other than that a fascinating podcast!

  • @Alistair_Spence
    @Alistair_Spence 11 місяців тому +2

    Very insightful questions, and very comprehensive answers. I learned a ton listening to this.

  • @carlynnerau
    @carlynnerau 11 місяців тому +3

    Thank you both for this in-depth conversation! 🙌💙 I look forward to Dr. Attias podcast on Breast Cancer. 🙏🎗️

  • @Ph4t3
    @Ph4t3 11 місяців тому +12

    As a long-time member, what a tremendous episode! I had to laugh at @2:22:25 when Peter just can't help himself and outlines a study design Mo should've done instead, basically telling him the one he did was trash, in a nice way though. Insane density of info and topics covered on this one, loved Mo as a guest, more like this please. These are the topics that it's extra hard to find advice you can trust.

    • @Kevin-qy9wf
      @Kevin-qy9wf 9 місяців тому

      I couldn't help but notice the same thing, that "ahh" and eye roll is so uncharacteristic of Dr. Attia but you can't blame him when Dr. Khera had already shared false information by that point.

    • @xyzzy4567
      @xyzzy4567 6 місяців тому

      I’m glad he pushed back. It doesn’t appear the issue is settled. It’s good to bring up, but there were clearly serious issues with the design of that particular study. Hopefully research dig into this further over time and get some more solid evidence one way or another.

  • @TruthQuest4700
    @TruthQuest4700 9 місяців тому +2

    This has been a very enlightening discussion and the idea of receiving this level of medical care and fine-tuning is off of my radar!
    My physician put me on T therapy in my mid-forties because it was below 200 and never ordered tests to check LH and FSH. I eventually found an endocrinologist to check LH and FSH but had to get off T therapy for six weeks before testing and being off T for six weeks is not pleasant. The test levels came back in range except now I can't get copies of the results from the lab because for some reason the lab orders indicated female and so the lab has no record of the results I can access.
    With the exception of obesity, I have all of those symptoms mentioned even with T therapy and it's very frustrating just trying to improve stamina.

  • @davidgrimes4726
    @davidgrimes4726 10 місяців тому +1

    Mohit was a fantastic guest! Just his smile is contagious! 😃 I also loved the discussion about PFS. At this point I think the most important question for any patient to ask a new physician is: what non-consensus views do you hold and why. If they can't come up with anything move along!

  • @christopherdixon2310
    @christopherdixon2310 5 місяців тому

    This doctor nailed it. Most comprehensive talk.

  • @ludobmw540i
    @ludobmw540i 11 місяців тому +5

    Androgen receptor density is increased by strength training, so one could argue that a 50 plus male who trains hard could benefit from going on trt

  • @Laz3rs
    @Laz3rs 11 місяців тому

    Amazing episode. This guest is great to listen to.

  • @LALA-dw2ez
    @LALA-dw2ez 11 місяців тому +4

    I hope that many people try it for premature ejaculation. The more people the problem PSSD have the bigger the desire to search for a solution.

  • @patricksandridge6242
    @patricksandridge6242 11 місяців тому +3

    Thank you 👨‍⚕️ & 🧑‍⚕️ this was an amazing episode with so much information

  • @Novilicious
    @Novilicious 3 місяці тому

    Incredible podcast Dr Attia. Please have Dr Gundry and Dr Lustig on your podcast as well. You ASK THE BEST QUESTIONS. No other MD quite like you!

  • @Snapkrackpop
    @Snapkrackpop 10 місяців тому +3

    Dr Khera is has been my doc for a few years now. He really is one of the best MDs out there. He has been treating me for hyposexual desire disorder. I’m thrilled to see him in this show as a guest.

    • @_FightForYourFreedom_
      @_FightForYourFreedom_ 9 місяців тому

      You are very lucky. Very few doctors know their subject the way he does. Which city is he located in please?

  • @giovannitolenaars1879
    @giovannitolenaars1879 11 місяців тому +24

    I skipped the video to PFS part, will watch the whole interview later. This man is woke about Finasteride, thanks for speaking out and taking PFS seriously! Time will tell alot and more then ever before.

    • @ballislife9924
      @ballislife9924 11 місяців тому +5

      This podcast actually raises suspicion of the validity of PFS if you actually listen to what they are saying. Kheras points get dismantled and questioned. And it's no coincidence that Khera is on the PFS Foundations payroll while having his studies FUNDED by the PFS Foundation. That's a real problem when it comes to objective research.
      He also says stuff that is just plain wrong.
      I don't understand how you can be happy with this video.

    • @anneboyer6359
      @anneboyer6359 11 місяців тому +2

      What? finasteride has been around for more nearly 30 years. what are you talking about?

    • @ethanbaggoo1513
      @ethanbaggoo1513 10 місяців тому +1

      ​@@anneboyer6359what's your point? There have been people reporting getting pfs ever since it hit the market.
      People have been reporting getting pssd for decades now as well, antidepressants still being readily prescribed doesn't discount the validity of pssd in the slightest

    • @bardsamok9221
      @bardsamok9221 10 місяців тому +1

      ​@@ballislife9924Quote something that's "plain wrong". Humour us with your expertise, instead of throwing pointless jibes with no substance.

    • @bardsamok9221
      @bardsamok9221 10 місяців тому

      ​​@@ethanbaggoo1513Did you even watch the video? He's perfectly clear about PFS being real in his opinion, and even explains the scientific basis for it being real.
      Pay attention.

  • @armandofelipe3462
    @armandofelipe3462 10 місяців тому +5

    Dear Dr Attia
    Thank you so much for bringing this subject to your podcast, I follow most of your content attentively.
    I have been suffering from PE for these last 5 years, I’ve visit with two urologist specialist and they both prescribed SSRIs. And sprays medication. Nothing has really help… I am an active person in considerably good health, 36 years old. I’ve tried it all. But sadly, nothing works
    I live in Richmond TX, in the greater Houston area. Is there anyone that you or Dr. Mohit can recommend so I can seek treatment…Thank you so much. 🙏🏻
    God bless

  • @Zoe.TheBody360
    @Zoe.TheBody360 11 місяців тому +6

    Brilliant information.

  • @MusixPro4u
    @MusixPro4u 11 місяців тому +10

    Highly informative, much appreciated! If there's one point of critique; Peter sometimes really does have a hard time containing his excitement, which outs itself in slightly jarring interruptions of the guest.

  • @paddy3622
    @paddy3622 11 місяців тому +9

    it almost sounds, to me, that taking 5mg prophylactically is the way to go. even if everything is good downstairs.

    • @TheBswan
      @TheBswan 11 місяців тому

      I assume you mean 5mg Cialis, rather than some of the other drugs mentioned. I'm not a doctor, but I agree that could make sense

    • @danilascercovas6226
      @danilascercovas6226 10 місяців тому

      Sometimes it's even considered as longevity drug

  • @IgrwOw
    @IgrwOw 10 місяців тому +16

    Post-finasteride syndrome is real. My life changed after taking topical finasteride for only 14 days. I have insomnia, anxiety, ED, low libido, tinittus, dry skin, dry hair, suic1de ideation and brain fog. its been 6 months I stopped taking finasteride and I still suffer.

    • @FedeArgentina
      @FedeArgentina 10 місяців тому

      Do you exercise?
      Zero .. or Some hours / week?

    • @IgrwOw
      @IgrwOw 10 місяців тому +1

      @@FedeArgentina I have been going to gym for 1 year every single day. 6 months before finasteride and 6 months after. I try hard and have low fat and defined muscles . 700 total testosterone, 20 free testosterone and 14 shbg. I should have up to 8 hours exercise weekly not including 1 hour cardio(runnings). My sleep was good, 9 hours daily, straight.

    • @IgrwOw
      @IgrwOw 10 місяців тому

      @@FedeArgentina I'm only 28 btw..

    • @IgrwOw
      @IgrwOw 10 місяців тому

      @@FedeArgentina been to a cardiologist before finasteride and before even goin to gym, my blood was simply perfect with close to zero bad cholesterol and very high good cholesterol. Been on diet since I was 18. Low sugar and fat diet.

    • @Casey53736
      @Casey53736 6 місяців тому +1

      @@IgrwOw I’ve heard low fat diets can be harmful for sexual health. Also you don’t need to go to the gym everyday you need some time for recovery

  • @ahrengroesch8774
    @ahrengroesch8774 7 місяців тому +1

    I'm asking my doctor about daily tadalafil because of this. I check all the boxes pointing to it addressing my problem. Atrophy makes too much sense. Thank you.

  • @Abdullah-mt9ns
    @Abdullah-mt9ns 11 місяців тому +10

    PFS ruins lives!

  • @christianstetz5235
    @christianstetz5235 10 місяців тому +1

    The Traverse study mentioned was published in NEJM July 13, 2023, and showed testosterone treatment did not increase the risk of ischemic heart disease.

  • @maximilian8339
    @maximilian8339 11 місяців тому +36

    Thank you for speaking out about Post-Finasteride Syndrome! It is a terrible chronic disease triggered by Finasteride that is destryoing the life of thousands around the globe and has caused hundreds of suicides already! We need more research to find treatment options!

    • @ballislife9924
      @ballislife9924 11 місяців тому +3

      This podcast actually raises suspicion of the validity of PFS if you actually listen to what they are saying. Kheras points get dismantled and questioned. And it's no coincidence that Khera is on the PFS Foundations payroll while having his studies FUNDED by the PFS Foundation. That's a real problem when it comes to objective research.
      He also says stuff that is just plain wrong.
      I don't understand how you can be happy with this video.

    • @AlexM-jd2ro
      @AlexM-jd2ro 8 місяців тому +1

      Agree wholeheartedly....in some countries they already figured out that Finasteride destroys prostate gland...

  • @JL2LB
    @JL2LB 11 місяців тому +4

    awareness is key! thank you

  • @SenorSS
    @SenorSS 11 місяців тому +5

    There are three isozymes of 5α-reductase encoded by the genes SRD5A1, SRD5A2, and SRD5A3. The guest said that there are only two. He also didn't even mention the PFS study conducted at Baylor, where he practices.
    pubmed.ncbi.nlm.nih.gov/34247957/

  • @robertkraychik1884
    @robertkraychik1884 9 місяців тому

    tremendous episode. thank you, gentlemen.

  • @ashdgee
    @ashdgee 11 місяців тому +2

    What an insightful podcast

  • @hkpestcontrolpestcontrol9216
    @hkpestcontrolpestcontrol9216 6 місяців тому

    Mohit khera is a great doctor.

  • @ConsiderItHealth
    @ConsiderItHealth 10 місяців тому +1

    Dr. Atilla, thank you for your continued high quality episodes.
    I would ask to please let the guests talk more and interrupt them less. We know how brilliant you already are and sometimes trying to clarify the minutia can distract from the big picture and enjoyment of listening to the info.

  • @clarencecalistro169
    @clarencecalistro169 7 місяців тому

    Good information, thank you very much.

  • @Annhienmoingay3333
    @Annhienmoingay3333 5 місяців тому +1

    You can forget many things but don't forget to exercise. Because health is a prerequisite to help you have a fully happy life.🥰

  • @Thechroniclespodcast
    @Thechroniclespodcast 9 місяців тому +1

    Let’s continue to cover these topics my good people!👍🏿👍🏿👍🏿

  • @N02tradamus
    @N02tradamus 2 місяці тому

    amazing interview

  • @rogerp1477
    @rogerp1477 11 місяців тому +1

    Very fascinating interview. Lots of good information. One question though. Dr. Mohit says he doesn't like Finasteride. For BPH he recommends alpha blocker or daily cialis? What about people who use Finasteride for hair loss? Any alternative? Thanks.

  • @ayan0834
    @ayan0834 11 місяців тому +9

    These are so important and enlightening conversations! Thanks a lot, docs! If I had a chance, I would like to get both of your views on SSRIs having "lingering" impacts on sexual health, along similar (e.g., epigenetic) or different pathways as 5AR inhibitors. SSRIs are so commonly doled out (much more commonly than 5AR inhibitors, in my experience), that any small risk of post-SSRI (lingering) sexual side-effects warrant a much more thorough look, including well-designed trials, etc., in my opinion. It tends to simply get shrugged off by professionals in the mental health profession, since it has been made out to be the "lifeblood" in treating anxiety and depression. Since Dr. Khera touched upon the "therapeutic use" of SSRIs in sexual medicine even (e.g., to decrease genital sensitivity, prolonging IELT by >10x), I would be fascinated to have real-world insight from people like him, as to whether SSRIs can potentially--in a small population of men--cause permanent negative sexual side effects, much like finasteride, which I personally agree with Dr. Khera's insight as being a "bad" drug to prescribe to men, period.

    • @ethanbaggoo1513
      @ethanbaggoo1513 11 місяців тому +3

      To have both of these persistent syndromes discussed like this in the mainstream is very heartening. If conversations like these continue to occur we could have a real shot at moving towards treatment for us sufferers. Acknowledgement is the first step.

  • @NY2CALINiclk
    @NY2CALINiclk 8 місяців тому +1

    I'm grateful for coming across this information. I'm 54 and 1 year post Radical Prostatectomy plus a nerve. Pulling my MF hair out.... I'm trying to spread the word for people to pay attention and get checked out...

  • @patrickr9931
    @patrickr9931 11 місяців тому +9

    Men are dying through suicide because compost finasterude syndrome. Unwilling shortly be one of them in likelihood I havemuwcleneastage and impotence.I had offensive 2009 and was mild for years in fact it i had visited theatricality he could have cured me.but Imlive innEyrope. I took seroquel for sleep and crashed again lost muscle libido total we I am a huge suicide risk also.bad insomnia

    • @jonathanmitchell8668
      @jonathanmitchell8668 6 днів тому

      Has it gotten any better? Any update? I hope things are going well.

  • @davetherave4599
    @davetherave4599 9 місяців тому +2

    Great episode. So much incredible information! Question. What do you do if you live in country (Israel)where HRT is hardly ever prescribed, no matter your symptoms. Or even blood work. If you're a woman, no problem. Gay and "transitioning?" Easy as pie. But a regular straight guy with all the classic symptoms, and with a Testosterone level normal only for a centarian? You are out of luck. What should be such a person's next step. Telemedicine? The black market and wing it? Any suggestions would be greatly appreciated.

  • @michaelsing5988
    @michaelsing5988 6 місяців тому

    It's a shame this type of information wasn't available when I was younger. I was pretty good at massaging but all of the preparation leading up to actually messaging wasvery little to none. You depended on your male friends to share the best way to approach the subject. Obviously, that was often a disaster. I would love to have those opportunities back again. I'm starting late, but at least I'm starting.
    Thanks for your videos. They're great!

  • @mr.o4610
    @mr.o4610 7 місяців тому

    Great Episode!

  • @erwinrogers9470
    @erwinrogers9470 9 місяців тому

    Great interview 🔥

  • @albertmeneses3132
    @albertmeneses3132 3 місяці тому

    I’m totally inspired by these guys and check out their biceps!

  • @mindofown
    @mindofown 9 місяців тому +4

    What might help men is to begin acknowledging the value of the prepuce and to stop removing the foreskin a functional pleasure giving sex organ from males especially as its done before they consent

  • @macfin4862
    @macfin4862 11 місяців тому +10

    Tramadol for premature ejaculation sounds like a recipe for disaster.

    • @paddy3622
      @paddy3622 11 місяців тому +2

      Ultram. Yikes. I agree with you

  • @willemvanriet7160
    @willemvanriet7160 10 місяців тому +3

    I had ED at 43. Was 100% psychological. I'm now 53 and only need Cialis after multiple consecutive days. It's mostly in the mind. Delay meds as long as u can.

    • @contrerasmcr100
      @contrerasmcr100 9 місяців тому +3

      Is in the mind but you need cialis? Come on man.....

    • @RHt09
      @RHt09 5 місяців тому

      You clear didn't watch the video where he explains why it works in psychogenic ED@@contrerasmcr100

  • @serinodiaz4140
    @serinodiaz4140 9 місяців тому

    Thank you! Do you use any of these knowledge on yourself or if you ever needIt?

  • @kvsurdas
    @kvsurdas 8 місяців тому +2

    Isn't GFC ( Growth factor concentrate ) better than PRP ( Platelet rich plasma ) ?
    For any treatment??

  • @qeva_
    @qeva_ 11 місяців тому

    Wow.. that's a ton of information

  • @MajorSpam
    @MajorSpam 11 місяців тому +1

    So the electrical treatment would be at 2hz, I assume?
    What about other non-medical, non-surgical treatments like ultrasound theraphy? Would it help to promote angiogenesis? At which frequency? 40khz, 60khz, 80khz, 1mhz, 3mhz?

  • @Pccoffee1776
    @Pccoffee1776 10 місяців тому +1

    Very informative lots to unpack. Why no mention of using Pregnenolone and DHEA to increase hormone down chain in HRT. Dr. Khera focuses on percent of free testosterone. I am curious to why not just increase amount of free testosterone vs increasing percentage?

  • @hfud11
    @hfud11 11 місяців тому +13

    PSSD ruined my life

  • @tamil1001
    @tamil1001 6 місяців тому

    I am a 50 year male suffering from a severe case of post finasteride syndrome since 2015 without improvement. I have multiple sexual side effects, chronic fatigue, muscle weakness, inability to gain any muscle mass, and insomnia. Its a horrible, horrible illness.

  • @Doormat00
    @Doormat00 9 місяців тому +1

    My lifelong type of anorgasmia is due to not feeling enough phyisical stimulation from coitus. I have a history of phimosis until I got circumsized 5 years ago. What can I do to remedy or improve sensitivity so that I can reach climax?

  • @fhowland
    @fhowland 10 місяців тому +1

    Was hoping to hear him talk about bike riding and how much of a risk factor it is for ED.

  • @kwats
    @kwats 3 місяці тому

    This is a Great interview .. Wondering, any of you guys getting that symptom of lacking feeling down there? Mine is primarily in the morning but I also feel like I'm not getting the feeling I used too.. (dont wanna use numb) but almost.. I just hit 50 yrs today.. I'm pretty healthy overall.. only thing I can think is that I occasionally use Delta 8 gummies to help me relax.. any feedback here from people reading the comments would be GREATLY appreciated.

  • @gif24gt60
    @gif24gt60 7 місяців тому +1

    What about low dose cialis with low dose telesmisartan?
    How do u reduce refractory period?
    Can't nattokinase or serrapeptidase help clear plaque?
    Inquiring minds need to know.

  • @alexryan9869
    @alexryan9869 26 днів тому

    What about endrocine disrupters. Hormone disrupters are everywhere. Also how about systemic enzymes to dissolve the fibrin. Also nattokinase, serrapeptase and k2 dissolves artierial plaque.

  • @clydeespinosa6286
    @clydeespinosa6286 26 днів тому

    Thanks Doc i love your channel. I’m 52 on 100 T sub q at 0.25 Sunday/Thursday and feel great for 6 months i have always had high LDL low triglycerides and high HDL. i don’t really want to take a statin however i saw another of your videos showing you take rouvastatin every other day and am curious i way 180 good music not over weight but could be a little leaner thanks

  • @karlstrand3328
    @karlstrand3328 11 місяців тому +6

    This information is amazing, but it would be so much better if Peter would quit interrupting his guest.

  • @jdsirrom4314
    @jdsirrom4314 9 місяців тому +1

    This is simply cured from much rest, diet, and exercise (the more consistent; the more the benefit!)! Remember when you were a child?

  • @FiberFairy22
    @FiberFairy22 11 місяців тому +6

    I wish the conversation was first about the connection between ED and vascular health - tiniest arteries in a man's bodies in that part so improving diet and lifestyle often improve ED! No drugs necessary in many cases 🥳

  • @eddiemartinez1337
    @eddiemartinez1337 11 місяців тому +2

    Is daily cialis better to be taken at night or in the morning

  • @unkwm128
    @unkwm128 19 годин тому

    That was my question: Would Heparin be used ? But Aspirin would work.

  • @patricklachance6880
    @patricklachance6880 8 місяців тому

    What about using DHEA for normalizing hormone levels like testosterone in men?

  • @hughtoobin7207
    @hughtoobin7207 7 місяців тому

    I am very interested in the kinetics of exogenous testosterone. I would appreciate a link to the studies that show that SC is 20% better that IM and that cypionate is more anabolic than enanthate. I have been searching but cannot find any study that demonstrates these claims. Thank you.

  • @darcybrown7369
    @darcybrown7369 8 місяців тому +1

    I've seen a few youtube videos about risks of blindness with use of PDE5 drugs such as cialis/viagra ? Primarily damage to the optic disc and nerves around that, any idea how common this is and if it affects men with certain pre-existing conditions? If it is a risk how often should men using such drugs get the back of their eye checked? Just figured if anyone could clarify this it would be you. Maybe you could interview consultant optometrists or similar. Thanks for all you do.

  • @jeffrey4577
    @jeffrey4577 10 місяців тому

    138:00 Dr attia were both anemic with low t and shbg etc it's our anemia but doesn't hold us back because we're metabolically fit

  • @MXF11
    @MXF11 11 місяців тому +4

    "Intratesticular testosterone." I like it.

  • @stephm4047
    @stephm4047 11 місяців тому +2

    45:59 a new daily training routine for Peter Attia now 😂😂😂

    • @mrv2308
      @mrv2308 7 місяців тому

      I can guarantee you a lot of dudes on here went and got that device.😂😂😂

  • @Dedicated_.1
    @Dedicated_.1 11 місяців тому +4

    Finally, no paywall!

  • @snasnusnaba3361
    @snasnusnaba3361 11 місяців тому +6

    Mdma worked extremely well to get rid off premature ejaculation for me. Never heard it mentioned anywhere. It's not a cure but a great tool... It's also not just adding 3-4min to the act, more like 30-40min.🎉

    • @macfin4862
      @macfin4862 11 місяців тому

      I found this in my younger years. I think it's very common unless you over do it and can't get it up

    • @bgoodorhell4u
      @bgoodorhell4u 8 місяців тому

      Where do you get MDMA from?

    • @oooooooohhhYEAH
      @oooooooohhhYEAH 8 місяців тому

      Seretonin plays a massive role in lasting long in bed

    • @milenavidmar2733
      @milenavidmar2733 7 місяців тому

      ​@@bgoodorhell4ufrom your dealer. Mdma is ecstasy in crystal form

  • @yashsawalkar8493
    @yashsawalkar8493 6 місяців тому

    Well I am 22 years old and have Peyronie's disease. I got when I was 16 years old

  • @drainmonkeys385
    @drainmonkeys385 Місяць тому

    Acoustic wave therapy is advertised around here is that a good option and for who, if utmis