Melanocytes vs Keratinocytes Made Easy: 5-Minute Pathology Pearls

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  • Опубліковано 10 вер 2024
  • A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/pos... (dermpath) & kikoxp.com/pos... (bone/soft tissue sarcoma pathology).
    Melanocytes and keratinocytes both can develop artifactual clear vacuoles around them. To dermpath beginners, this can make them difficult to tell apart. Once you know the trick, you can usually distinguish vacuolated melanocytes from vacuolated keratinocytes easily on H&E. And yes, I know this one is technically longer than 5 minutes. ;-)
    Thanks to my former medical student, Sophia Ly, for typing up the transcript of this video so it could have accurate closed caption/subtitles! You can access a text version of her transcript of my video here: kikoxp.com/pos...
    Other videos:
    - Normal Skin Histology: • Normal Skin Histology ...
    - Melanoma Basics: • Melanocytic Dermpath B...
    This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
    Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
    Follow me on:
    Snapchat: JMGardnerMD
    Twitter: @JMGardnerMD
    Instagram: @JMGardnerMD
    Facebook: / jmgardnermd

КОМЕНТАРІ • 70

  • @JMGardnerMD
    @JMGardnerMD  3 роки тому +4

    A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

  • @triad6425
    @triad6425 5 років тому +39

    I can't tell you how amazingly clear this video was. No one I asked could ever tell me why a melanocytes was a melanocyte.

    • @JMGardnerMD
      @JMGardnerMD  5 років тому +4

      I am so happy it helped you! Makes me glad to know these videos are benefiting others.

  • @janexu9653
    @janexu9653 10 місяців тому +1

    I would rather ditch my histology class and just watch your video. Thank you for making it fun to watch and learn

  • @giulianomorgantetti9533
    @giulianomorgantetti9533 5 років тому +12

    Dr Gardner, thank you so much for sharing your knowledge. People all around the world benefit from your help. Please have my gratitude

    • @yilmerchiquito2799
      @yilmerchiquito2799 3 роки тому

      hi everyone ,if anyone else wants to discover keratosis pilaris home remedies try Elumpa KP Remedy Alchemist (Have a quick look on google cant remember the place now ) ? Ive heard some pretty good things about it and my buddy got cool results with it.

  • @radosawwujec959
    @radosawwujec959 5 років тому +8

    OMG... Ive got no idea how many hours I've spent on that topic .... when its so easy,... wish I was doing residency under your supervision... anyway HUDGE thanks.

  • @GiuseppeG1993
    @GiuseppeG1993 5 років тому +6

    Dear Dr. Gardner, thanks for your videos. I am an Italian DVM and Inter of the Veterinary Pathology Division of Utrecht University, I will start my residency in veterinary pathology in the near future. For me your videos are something great, they are clear, easy to understand and as this one, short, so a perfect combination. I wanted to say only thanks for what you do, is very useful and interesting!

  • @shadana.s.3575
    @shadana.s.3575 4 роки тому +1

    I can't thank you enough.
    u r a role model.
    how amazing are your videos.

  • @harishchenna2486
    @harishchenna2486 5 місяців тому

    Thank you, good differentials between melanocyte and keratinocyte

  • @tokunbohodubanjo5301
    @tokunbohodubanjo5301 2 роки тому

    I like to talk about these cells as if they're people. Dr Gardner is a nerd, like most other pathologists are. I know because I'm a pathologist too. Thank you for another clear and helpful video. I'm a huge fan of your videos, your work and your mastery of the subject of Dermpath in general.

  • @palkagouria7428
    @palkagouria7428 2 роки тому

    Crystal clear concept.
    Thank you Dr Gardner for that amazing explanation.

  • @poprostuklaudia
    @poprostuklaudia 5 років тому +3

    Wow now I can say that I understood the melanocytes 🙌🙏 thank you!

    • @JMGardnerMD
      @JMGardnerMD  5 років тому +1

      Awesome! If you want to learn more about melanocytes, check out my nevus video (ua-cam.com/video/jKZDqJez9jw/v-deo.html) and my melanoma video (ua-cam.com/video/8N0IZZpF8ts/v-deo.html) too.

    • @JMGardnerMD
      @JMGardnerMD  5 років тому

      Awesome! If you want to learn more about melanocytes, check out my nevus video (ua-cam.com/video/jKZDqJez9jw/v-deo.html) and my melanoma video (ua-cam.com/video/8N0IZZpF8ts/v-deo.html) too.

  • @evelyne7071
    @evelyne7071 3 роки тому +1

    BEAUTIFUL

  • @RaulRodriguez-sh6vb
    @RaulRodriguez-sh6vb 2 роки тому

    Very helpful video. I had never heard these very important details to differentiate between the two. Amazing

  • @christinemorsink1993
    @christinemorsink1993 2 роки тому

    Excellent teaching video. Humanizing the human cells is a helpful in making the distinctions “stick” for me. Poor keratinocytes, naked and alone. I’d love to see you examine some, woven into tough fibers, from a patient with Morgellon Disease. Also to hear what you think about the unique physiology.
    Thanks for teaching us well.

  • @TheBradmd
    @TheBradmd 2 роки тому

    What a great pearl. Thank you for doing this video.

  • @LanTran-wb7dd
    @LanTran-wb7dd 5 років тому +1

    I really like your videos. Thank you for making it available to all of us.

  • @preethipaul7180
    @preethipaul7180 5 років тому +1

    Superb teaching video! Love the quality and staining of slides as well. Thank you so much, Dr Gardner, for doing what you do and being an inspiration to many.

  • @IzzatAlJaberi
    @IzzatAlJaberi 4 роки тому +1

    Thank you so much sir for your amazing videos ! Love from Jordan

  • @dibyanshusekharmohapatra9929
    @dibyanshusekharmohapatra9929 4 роки тому

    Beautiful demonstration. Thank you sir

  • @DocRicForensicSpecialist
    @DocRicForensicSpecialist 2 роки тому

    Another very clear discussion..thanks doc

  • @HonMaguro792
    @HonMaguro792 Рік тому

    Thanks jerad! This video helps me a lot!❤

  • @amberk7459
    @amberk7459 2 роки тому

    Great video! I’d love to see a video about how/why these melanocytes respond to 532 or 755nm laser.

  • @hayder5391
    @hayder5391 4 роки тому +1

    thank you sir for this amazing video🙏

  • @rubeenabano4803
    @rubeenabano4803 3 роки тому

    Thank you for the great video. Waiting for more videos on dermpath

    • @JMGardnerMD
      @JMGardnerMD  3 роки тому +1

      A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

  • @zainabnasir8943
    @zainabnasir8943 2 роки тому

    Thanks 🙏🏻

  • @molayroy123
    @molayroy123 3 роки тому

    Very well explained. Thank u so much🙏🏼🙏🏼

  • @cthulhu9306
    @cthulhu9306 Рік тому

    Thank you sir😊

  • @AnhNgoc-qf8db
    @AnhNgoc-qf8db 2 роки тому

    Very helpful video. Thank you so much❤

  • @drbonitaborah6752
    @drbonitaborah6752 4 роки тому +1

    Cant thank you enough

  • @missknowall
    @missknowall 5 років тому

    So beautifully described! Thank you.

  • @josefsterner6000
    @josefsterner6000 3 роки тому

    Great explanation!!! Thanks dr buddy!

  • @reshmakini8701
    @reshmakini8701 6 місяців тому

    Fantastic

  • @xiaoouli9021
    @xiaoouli9021 5 років тому

    The explanation is brilliant!

  • @luciakim5668
    @luciakim5668 8 місяців тому

    Why is it that the vacuole forms outside of the melanocyte during processing? I'd expect it to shrink with the cytoplasm not emerge outside of it.

  • @hamedisya1267
    @hamedisya1267 2 роки тому

    Thank you for the great video

  • @bosnian_beauty
    @bosnian_beauty 5 років тому +1

    Thank you!!!❤

  • @aparnavinod007
    @aparnavinod007 5 років тому

    Thank you sir... beautiful description....

  • @rabiataseer8369
    @rabiataseer8369 5 років тому

    Beautiful, thanks.

  • @crenapun57
    @crenapun57 3 роки тому +1

    tq

  • @docdihya2466
    @docdihya2466 5 років тому

    Thank you

  • @drritikasondhi9432
    @drritikasondhi9432 5 місяців тому

    Sir pls upload video on vesiculobullous disorders of skin

  • @evelyne7071
    @evelyne7071 10 місяців тому

    Beautiful melanoma. Is it true that African Americans have extra-cellular melanin, whereas European Americans have intra-cellular melanin (as shown)? It would be interesting to see the differing histology of their skin side by side for comparison. Where does the “melanin cap” reside in people of African descent ? Is that why they don’t get melanoma except in their nails and soles of feet ? Please clarify why they are immune to the sun’s ultraviolet effects.

  • @Dresaivanikb4644
    @Dresaivanikb4644 3 роки тому

    Sir u are rocking 😀

  • @amaliyadipita6906
    @amaliyadipita6906 6 місяців тому

    ❤❤❤❤❤

  • @lukedebenham208
    @lukedebenham208 6 місяців тому

    VVVV nice video

  • @sirwanahmed3561
    @sirwanahmed3561 Рік тому

    👏👏👏

  • @jasspreet5686
    @jasspreet5686 5 років тому +1

    nice video explanation, can u explain koilocytotic change if possible?

    • @JMGardnerMD
      @JMGardnerMD  5 років тому +2

      Will try to cover that at some point. I think I touch on it in this video if I recall. ua-cam.com/video/G31xlSgYSlw/v-deo.html

  • @firdauszakaria7794
    @firdauszakaria7794 3 роки тому

    thank you for simplifying this! are there any videos where you show eos/neutrophils?

    • @JMGardnerMD
      @JMGardnerMD  3 роки тому

      Maybe I should make an eosinophils vs neutrophils video. Good idea! Thanks!

  • @pangalaxy9332
    @pangalaxy9332 Рік тому

    Well, good video. But how vitiligo works then. Do you know?

    • @JMGardnerMD
      @JMGardnerMD  Рік тому

      It’s a type of autoimmune disease where lymphocytes (white blood cells) attack the melanocytes and destroy them. This leads to loss of skin pigment in the affected areas.

  • @mass131987
    @mass131987 3 роки тому

    wow

  • @c.rguez7404
    @c.rguez7404 Рік тому

    You are so goood!

  • @roseanacoscos6789
    @roseanacoscos6789 3 роки тому

    Who discovered keratinocytes or who named keratinocytes

  • @goharrehman7710
    @goharrehman7710 5 років тому

    Dr Jerad please show us langerhhans cells

    • @JMGardnerMD
      @JMGardnerMD  5 років тому +1

      I discuss Langerhans cells in ua-cam.com/video/yQQ2Dmz42Vs/v-deo.html

  • @giuseppebuonocunto6769
    @giuseppebuonocunto6769 2 роки тому +1

    Dr Gardner can you speak More slowly? Please and thenks

    • @JMGardnerMD
      @JMGardnerMD  2 роки тому +2

      I have been trying to speak more slowly my whole life but unfortunately I’ve been unsuccessful so far! Even most native English speakers say that I speak too rapidly. I’m sorry! Some of my videos have English subtitles. Also you can adjust playback speed to slow the video down. Click settings button in bottom right of video for these options. Best wishes.

    • @giuseppebuonocunto6769
      @giuseppebuonocunto6769 2 роки тому

      @@JMGardnerMD thank you for. All Dr Garder