The Breath of Life: Demystifying the Ventilation-Perfusion Ratio in Respiratory Physiology! | MBBS |
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- Опубліковано 27 вер 2024
- What is the normal V/Q ratio? What is the effect of gravity on this ratio? What will be this ratio in the condition of weightlessness? Watch the video for the answers.
Dive into the intricate world of respiratory physiology as we unravel the concept of the ventilation-perfusion ratio. This video is your gateway to understanding how our lungs optimize the exchange of oxygen and carbon dioxide to sustain life. We'll explore the dynamic relationship between ventilation (airflow) and perfusion (blood flow) in the lungs, and how imbalances can impact respiratory health. Whether you're a medical student, a healthcare professional, or simply curious about the mechanics of breathing, this video provides a comprehensive and enlightening guide to the ventilation-perfusion ratio. Join us and breathe in the knowledge of how our bodies maintain the delicate balance of respiration!
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Sir u r a best physiology teacher that i have been seen.......
Thanks!
Thanks for the words of appreciation. I will try to live up to the expectations of students.
Regards,
Conceptual lecture ❤️
Thank you sirr
Thankyou sir!
Thank you
thanks a lot.so clearly explained
👌
Thnq sir
Tqq sir :)
Sir what will be the effect on ventilation and perfusion when alveoli are compressed due to weight of lungs,
When alveoli near the base of the lung are compressed due to weight of the lung, one fall out of that is - they are smaller in radius. It means, surfactant is concentrated. This results in a lower surface tension, and higher compliance. Hence, ventilation per unit lung volume is said to be greater at the base as compared to apex. Blood vessels donot get compressed due to the weight (to a large extent). Reason - Higher pressure in those vessels , as blood is going TOWARD gravity.
The best vedio.... Thank you sir😊
Thanks….regards.
Sir U gave an mcq in class
Helium dilution method was used to measure RV. Initial He conc =10%, Final He conc=6%.
Volume of spirometer= 2L. How much is RV.
U didnt explain how to calculate
V2= v1(c1-c2) /c2. V2=2 (10-6)/6= 1.33 litres
@@dr.rishisharma8535 IS NOT IT THE FRC?
Sir i have couple of ques to ask..
1.Why does the ventilation Increase down the lungs..??
2.Is there any relation between V/q ratio & size of alveoli..??
3.in case of physiologic shunt why does the Alveolar pO2 in normal istead of it should be more as the alveoli at base are small & so there are capable of inhaling more air..??
1) Why ventilation goes increasing toward the base? Two reasons - (a) The shape & architecture of the lung. It makes the expansibility less at the apex and more toward the base. The conical shape at the apex can be pulled only in certain dimensions. Toward the base, the additional downward pull of the diaphragm is causing the alveoli/lungs to expand in greater dimensions. (b) Alveoli near the base are small at the start of inspiration (compressed due to weight of the lung). So, they have lower surface tension and higher compliance.
2) Relation between V/Q ratio and size of the alveoli - Ventilation itself is determined by the size of the alveoli. Thereby, it does influence V/Q ratio. But, the ratio itself is governed by TWO factors - ventilation (size of the alveoli) and the blood perfusion.
3) Alveolar PO2 also differs from apex to base. This is the reason why certain foci (e.g. TB) are found more in certain regions (apex in the case of TB). For instance, more of ventilation and RELATIVELY lower blood flow at the apex makes the PO2 at the apical alveoli higher (as diffusion from alveolus to blood is less, due to less blood flow).
So yes, PaO2 value of 104 mm Hg is an averaged out value. It's different in different regions.
Can you explain all this but in supine posture?
Sir if at base of lung there is decrease surface tension and increased compliance... Sir, then Will increased compliance doesnt lead to increased ventilation?
Another question is
Ambient pressure at which plasma water will boil spontaneously?
Is it 47mm hg?
So in case of zero gravity there will be no physiologic dead space n shunting? V/q ratio will be same throughout lungs?
Basically, it is the gravity that influences the blood flow; different flows in different regions. Gravity (weight of the lung) also compresses the alveoli near the base of the lung. Thus, gravity creates these variations in the V/Q relation. In the absence of gravity, V/Q ratio will remain the same throughout the lung.
Great thank you soo much
Thank u so much sir
👍👍👍
Sir ; in alveolar ventilation coupling
increase perfusion due to increase cardiac output so the ventilation must be increse due to increase perfusion what cause this ??
Can you please elaborate on the doubt? Ventilation and perfusion are independent of each other. Ventilation is due to the respiratory movements; perfusion is due to cardiac pumping. They don't influence each other.
@@VivekSirsPhysiology yes sir
This what written in our book
That when the ventilation increase o2 cause realese of nitric oxide that cause vasodilation and this in turn increse the blood flow at the same time because of low co2 it cause constriction to the muscle that surrounded the bronchiole to prevent co2 from reaching to very low level.sorry sir this point very confuse me
@@VivekSirsPhysiology sorry sir do u have any thing to contact with u we need u so much ur the best explinator
@@tibayounis9977 Fb page/messenger , insta account . All have the same name 'vivek sir's physiology'. Communication is easier and rapid on those channels.