Poop Treats Parkinson’s (and Allergies, and MS, and Liver Disease, and...)
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- Опубліковано 7 лют 2025
- Fecal transplants are often associated with treating intestinal issues, but they have uses far beyond that. In this List Show, we explore five surprising conditions they improve.
Hosted by: Hank Green (he/him)
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I’ll say anecdotally that my worst symptoms from autism are improved when I am focusing on my gut health; more fiber, fermented foods, more water, overall healthier (more plants!) seems to make my sensory issues, overwhelm/overstimulation, etc better.
That’s something that I’ve often heard from the autistic community
Maybe there's some low key immune response going on all the time too. It's the same for me, and taking an antihistamine (cetirizine) after eating unhealthy for a few days helps quite a bit. I'm supposedly not allergic to anything i'm eating drinking or breathing... though there's probably something maybe one of the byproducts of breaking down the trash food. Give it a shot maybe it helps you as well :)
That's good to know. My granddaughter seems to feel worse when she's eaten fast foods and not drinking enough water.
keto did wonders to me
I have personally witnessed juvenile onset diabetes become more easily treated when the diet was as you describe.
For widespread implementation, they should call it "intestinal microbial transplant". Getting an IMT sounds less gross than eating poop.
I think that you're on to something there!
I prefer
Transpoosion
As someone with rheumatoid arthritis, severe allergies, and IBS, I really hope this research speeds along and treatment is available to people once the science demonstrates it is safe and effective. I worry that unless it is seen as profitable, the progress will be very slow especially with the new administration's slash and burn approach to government funding for medical research and communication.
People at home after watching this: “Honeeeeey! i got a weird ask, and I swear it’s not a fetish thing” 😂
1min in..
"Further a deuce" 😂
Dis gonna be a good one!
They know about the spice. The spice melange.
the spice..
@@false_alice the brown water of life.
damn it, you beat me to it!! xD
lol only clicked on the story to see this comment from the South Park episode One for the ladies
Spice must flow!
Ahahaha I have MS and when I saw the title of this video my brain broke for a moment
I do too which is why I clicked on this
@@eblckmn Same here. After I recovered from my broken brain I was left with nothing but more questions and intrigue
I hope you haven't been suffering long. This treatment has long been know to reduce inflammatory responses that people with neurological and other issues suffer from.
However, it's hard to make a profit off it since you can't patent poop. Currently FMT is illegal in the USA with the rare exception for C. Diff. overgrowth infection.
Maybe our new HHS secretary will be able to reform the system a bit but I'm not holding my breath (unless dealing directly with the product. 😂😂😂😂
Do you know Dr Wahls? Please look in to their research and experience
Gotta be honest, I just saw the 30 second preview and I haven't watched the whole thing but I have to say "without further a-deuce" really got me. Good one.
Would be very interested to try this. With serious IBS, stubborn allergies and autism to boot.
Who knows where the future of medicine can take us!
Sorry, FMT is illegal in the US with rare exception. Maybe someday it will be available.
eating ass?
Removing sugar and carbs helped me enormously.
They kill the healthy gut bacteria.
@@The_Savage_Wombat Wrong. Fecal microbiota transplants (FMTs) are not illegal in the United States, but they are regulated by the FDA. They are usually covered by health insurance plans, but coverage depends on the plan and the circumstances.
My mother recently died of MS after being diagnosed 34 years ago. It was to the point where she was having trouble swallowing and breathing. She also had excruciating nerve pain and headache. I wish we had known about this.
So sorry for your loss. It's tragic how much suffering comes from inflammatory diseases.
FMT has been known to reduce all sorts of inflammatory diseases for many decades. But FMT can't be patented and it's illegal in the US with the rare exception of C. Diff. overgrowth infection.
There hasn't even been many studies comparing the microbiomes of those suffering from inflammation with healthy people. It would be so easy to do this and it would tell you which microbes you need (probably hundreds are missing due to antibiotics and pesticides in food).
@@The_Savage_Wombat it's unbelievably tragic that the only thing holding things back is a damn patent.
Love the little poo pun cascade at the start! You and John remain my favourite dad joke dispensers.
I’m autistic. AuDHD to be precise..I have self-experimented with various probiotics and have noticed a degree of change in my mood, motivation, and bowel movements. I still have autism, i just suffer from it differently depending on how healthy i am, what I’ve been eating, the sleep i manage to get, and I’m sure all that influences my microbiome. I also noticed that if i am forced to take an antibiotics without taking a probiotic too, i fall into an abyss of despair and depression. I think it’s very much plausible that a microbiome transplant might have an effect on all those things if my resident populations get an upgrade in genetic variance and microbe diversity. I do not know if I’d be willing to ingest something that came out of someone’s back end though…unless the colonies have been isolated. I’d consider self-experimenting with it then. :D
Very few probiotics make it to the point of the digestive tract where they're needed. Even then, there may be hundreds of different types that are needed for a healthy immune system and you are only getting a few of them. FMT is the way to go but there is no money in it since you can't patent it. Also, it's illegal in the US except in rare instances.
It does need more study since there was a single case of a person who contracted hepatitis from it. It needs to be done safely.
Fecal transplants is something we teach in sixth grade science classes in California, at least in schools using the Amplify Science Curriculum. The unit is about the gut microbiome, and fecal transplants are the main phenomenon we focus on for the unit.
Love this episode! also studies have been done on another autoimmune condition - ankylosing spondilitis and a strange overgrowth of bacteria (klebsiella) in microbiome that could be contributing to it. With more research, studies and trials - its possible that fecal transplant could be used to treat this condition too.
“There’s no money to be made”. Sadly this is true. There’s no drug to produce, no highly skilled procedure to perform.
What an excellent video to watch while I make lunch!
0:27 Hank you enjoyed saying this too much
To treat GI stasis in guinea pigs, some vets advocate encouraging the sick piggie to eat healthy guinea pig droppings, or even feeding them a "poop soup". I wondered when the idea would catch on for humans, especially now that we've learned more about gut biomes, microflora and so on.
i'd like to try this...but not as a poop soup, sorry! has me thinking of brown potato soup with chunks of, well, yeah, no.
@@chrisperry3525 🤣🤣Good thing you're not a guinea pig with gut stasis!
I don't think it would catch on, as most people hate the idea.
If the treatment was swallowing capsules containing freeze dried "product", or having a small amount of liquid squirted inside, then that would be tolerable to most people, if their doctors would recommend it.
Soup no, but capsules or enema yes.
@ People, yes. We are conditioned from birth about the "ick". But coprophages like guinea pigs and rabbits need to eat their cecal pellets, which are totally different from their fecal pellets. In a herd of guinea pigs, those that are ailing will often eat fresh droppings from others and get better in several days.
@@rachelwickart275yup. Different digestive systems. The first poops of animals that digest food twice is different. We don't process poop that way and I would think it's too risky to go fresher than a time released capsule to consume.
I lost it at "without further a-deuce" 😂😂😂😂
What a wonderfully worded word play to start this webisode: “without further a- deuce here’s what poo poo can doo doo for you”
OMG - I need this so badly. My year round allergies are insane.
My stepdad drank a lot, his cirrhosis of the liver eventually turned to liver cancer. This rate that they finding other options to help people in those predicament.
Would love to try it to manage IBS. If any scientists out there need to collect data, I am up for it
There's plenty of evidence for it helping with that too! Microbiome transplants are wild
If you search Google, you can find a site that lets you sign up for clinical trials. I did it for depression, so I believe you could find trials for your IBS. Good luck with it.
Yes, we can all provide loads of evidence.
When I tell someone to "eat sh*t" I'm really just looking out for their health. I've been misunderstood this whole time. ☹️
2:38 if somebody gave me an enema and it didn’t even do anything, I’d be pissed. Somebody owes that control group an apology.
Well, now I'm about to go down a rabbit hole researching about how poop could be helping my MS...THANKS 😂
Which biologist looked at the Australian Drop Bear and thought: "If it works for them, it could work for us as well"?
Ohmigosh I love Hank soo much! What poo poo can doo doo for you 😂😂😂
you will not believe this but i just recently started working in a company who are doing a first time full scale trial for FMTs in India focusing on Ulcerative colitis, and everyday, to motivate myself, i watch Hank's Ulcerative colitis song video. we have so many more innovative approaches to this and hoping to come up with a standardised version of this procedure! was gonna pose a question for DHAJ but here you are!
Didnt they do a south park episode about this?
Yes
THANK YOU. IVE BEEN TELLING PEOPLE THIS FOR LIKE 7 YEARS AND NO ONE LISTENS BECAUSE NHS DOESNT RECOGNIZE THE IMPORTANCE AND INFLUENCE OF YOUR GUT MICROBIOME ON EVERY ASPECT OF YOUR HEALTH.
I have a hypothesis regarding the allergy topic.
Lower microbiome diversity's affect on the immune system could, both increase your suseptibility to allergies and at the same time supercharge your immune system so that you just don't get common communicable diseases.
Allergies are also linked to a lack of worm infections. Worms normally surpess your immune system and when released from that supression our immune systems become overactive. That overactivity would not just have negative consequences, it would also make our first line defence against infection more effective at prevention.
If some gut bacteria have this same addaptation to supress the immune system like paracitic worms do (they are presented with the same selective pressure in the same environment so its pretty likely).
*Parasitic.
Certain innocuous worms can have a beneficial effect on inflammation. But is it the worms or is it the microbiome the worms bring with them?
Other types of worms can be really dangerous.
that matches up with the study that found microbiome has a strong effect on cravings. what you crave and such
I found this myself. If I eat a lot of sugary food, then I crave sugary food. So the idea that gut bacteria can change how you think, matches with my own experiences.
Parasites can also change their hosts behaviour, so bacteria affecting their hosts, may have a similar chemical signalling mechanism.
also anxiety. my worst anxiety is when I eat poorly late at night then wake up and start worrying about all the worlds problems. I think all or most of my anxiety is also diet and exercise related as well. The less we think of the gut bacteria as our gross little tummy zoo and more of we are their big meat bags performing the functions they desire the better. They aren't happy when their meat bags don't treat them properly and let us know, but we misinterpret these messages. Early days humans mostly only had to worry about where to get their next meal so general anxiety gets you on the right track of solving the problems our microbiome underlords desire
@@Billionth_Kevin I love the way you describe things. "Gross little tummy zoo"... "Big meat bags..." "Microbiome underlords". Awesome.
@@Billionth_Kevin I'm curious if you heard about breathing exercises to calm you down during panic attacks?
I'll get a plastic bag, and breath in and out of that. The enclosed air gets enriched with exhaled carbon dioxide, which calms me down rapidly. It works faster than any tablet, and there's no tolerance.
Depression is my main thing, but I hear anxiety can be equally debilitating. I hope you're able to figure out what works for you, and be able to not let it restrict your life too much.
Woooah! This is really exciting! :) Hopefully research keeps going into all these things!
I wish we actually understood the human microbiome and could control which bacteria are in us so we could only have to good stuff and none of the bad stuff. I have SIBO (methane variant) and am a mega-methane producer. Humans are really not meant to have methane in them and I have TONS of it. I'm constantly distended, nauseous, severely constipated and in pain. But there's no antibiotic that can kill the archaea that produce methane gas. :/ I've tried tons of treatments and none have worked. Methane SIBO is known for being almost impossible to clear and remission rarely lasts long. We really need to learn how to properly manipulate the microbiome.
Remind me not to anally kiss you 😬
There probably are some microbes that can kill the methanogens effectively, but I haven't looked into that subject. My guess would be if you've already explored commercially available probiotics (e.g. Akkermansia muciniphila, Bifidobacterium breve, Bifidobacterium infantis, Lactobacillus reuteri, Saccharomyces boulardii, Bacillus subtilis, Bacillus coagulans, etc.), then some more obscure fermented foods from far-flung regions might have bacteria or yeast that are capable of doing it. Just a guess, though.
@@zivzulander It's a problem that also extends to the livestock industry-- since methane is so damaging to the atmosphere we've been trying to figure out how to reduce these emissions from cows... But we still haven't figured it out, even with that huge incentive.
That's a horrible situation. I hope a fecal transplant can help.
I'd need to try both and then see which I prefer.
For people who are interested in whether this would help your medical condition, you can look for a clinical trial. This seems very promising but also the donors need to be screened well to make sure you’re not ending up worse off in some unanticipated way.
This medical research seriously needs more people studying in it and more funding.
Omg, UC is the worst. I’ve been keeping an eye on fecal transplant / gut microbiome research for like over a decade now. It’s really interesting stuff.
So, some of those poop eating vids I have "heard about" on the dark recesses of the web had something therapeutic behind them, lol. 🤣😁👍
Dang. I was listening to the beginning and thinking to myself 'man, if only this would work on my m.s., I'd do it in a heartbeat.' I wonder what my doctor is gonna say when I ask about this.
"Here's what poo poo can doo doo for you you"
There I fixed it TuT
This may sound awful, but I'd totally like to have one of those for my microbiome diversity! I have so many issues with my digestion 😢
wild foraged mushrooms can do this too, a great healthy habit.
@jesipohl6717 just be careful to not pick the wrong ones 🤢
Me too. I'm ready to sign up.
Dogs are smarter than us all!
Turns out the human centipede is the ideal form for humanity!
I can believe the gut has something to do with Parkinson's, allergies, and autism. I have all 3 and I've noticed that what I eat determines how severe the symptoms will be around 48 hours later. Junk food became a thing when I was in my early 20s. By my middle 20s I was starting to show symptoms of sensitivity to junk food. But I was dependent on the stuff, due to a chaotic lifestyle, so eliminating fast food, and commercially prepared foods, wasn't easy. Now that I'm in my 80s, I'm paying a heavy price for my food addictions. I'd be more than happy to use fecal therapy but first I have to clean up my diet that is still too heavy on the wrong foods.
The question I have is how does the science/medical community evaluate what a healthy gut biome / poop sample candidate is? Can we introduce new problematic conditions to a patient because we don’t know what to look for in a fecal donor yet?
Diversity of microbes is what they are looking at, first and foremost, besides fewer pathogens. There are some keystone bacteria and yeast, as well, that can hint at a relatively healthy gut microbiome.
Overgrowth of a few species vs an abundance of probiotic strains usually hints at a less healthy microbiome, the same way a macro scale biome (or ecosystem) will have a balance of different organisms (e.g. a city vs a pristine rainforest).
That said, it's still early days in this field.
I absolutely know that gut bacteria affect autism symptoms. More attention needs to be paid to this!
12:33 THIS. People are not gonna pay a lot for poop.
It sounds like my allergies, my IBS, & my ASD might be interrelated. Not surprised. Can I get in on one of these studies?
Fecal transplants could also help people with hypothyroidism and hashimotos.
Fun fact: In the fourth century in China, diarrhea was treated with yellow soup, a broth made from fermented or dried stool from a healthy donor.
I have Lupus, Fibromyalgia, Osteoarthritis, Osteoporosis, Juvenile Rheumatoid Arthritis, and IBS-C. I wonder how much a poop transplant might help me.
I need this hope they start using this more
Anyone going to mention orgies as a study case for this? 😂 I feel like people have been transplanting fecal matter unintentionally already (along with stds sadly)
For anyone grossed out, it’s ok, I grossed myself out as well.
Now can’t wait to see people bragging about being universal fecal donors 😂
Alan Alda is going to love this!
I think this has been an ongoing thing for longer than a few years. I recall hearing about it many years ago when my mother sent me a link to the studies being done. I've dealt with autoimmune issues since i was young. My immune system has always been pretty crappy. I had a ton of infections when i was a kid, especially UTIs and upper respiratory ones. I was on antibiotics a lot, so my gut biome is shot to hell. I take probiotics here and there, but sometimes they give me issues in my gut, so i lay off for awhile. I'm sure all the medication I've been on for years, including every SSRI on the market, has added to the imbalance in my poor gut.
I'd honestly love to do a fecal transplant, but since it's still in its infancy regarding testing, it's probably not available to me, at least in the way of insurance covering it.
It's sad as hell that money is one of the contributing factors of this amazing discovery not being tested like crazy. That's a capitalistic society for you. 🙄 I hope other countries are doing the testing instead. This needs to be utilized in clinical settings asap. So many lives can be made better if this is something all doctors can prescribe/recommend as a viable treatment option.
What a cool video!
Lol they used the same microscope stock footage at 3:50 that Veritasium used in his video a couple days ago
How do they standardize this? For this to work, the donated fecal matter needs to be good. You could even get unlucky and receive sub par fecal matter which would either do nothing good for you or even worsen your symptoms? Cant we just do it the probiotic way? Figure out the good ones and make it into a suppository?
How do they pick the "donors?" Do they have to undergo a large series of tests first? I don't know who would want to do that
They recently offered to pay people in Winnipeg if they are incredibly healthy, like go to the gym and they have very consistent bowel movements, to get paid for stool samples
So at the moment it’s like “do you 💩 good? give us some!”
The get paid for your poop donation posters on billboards and telephone poles.
They test the feces to see if it has a normal spectrum of bacteria and other microbes, and do other normal screening tests beforehand.
i am working on this and have reviewed almost every paper published on this topic. the donors chosen are usually the relatives of the patients and they are quite determined to set this out even if they have to pay plenty of money for it. we're looking at some "standard donors" who have the most ideal microbiome to work best for all recipients. the technique is pretty new so we're doing a full scale donor focused trial to determine the standard procedure for screening.
Pooping back and forth forever ☺️
Who wrote that banger line before the intro, I need to know
Now we need to study if people with a skat fetish have a lower than average incidents of these various conditions.
not my autistic ass simultaneously watching Hank and a bird for a few seconds before it sinks in that Hank is at that very moment explaining that this is a symptom 😅
Can the bacteria just be grown and put in capsule form to take without the poop?
We have to find out exactly which families of bacteria it will be (& it will be several groups of bacteria & not just one or two) & isolate those before we can simply "make a pill" out of them. This research will likely take years.
@@DrachenGothik666 Agreed but maybe a parallel study to know what kinds of food to eat to maintain the change in the biome
i already knew about this but its cool scishow is getting it to the wider public! my uncle has severe crohns and we've often thrown around the idea of a poop transplant from his daughter (who has like... the healthiest gut/intestines/colon in the world. its crazy). sadly its not really feasible. but its been years of us talking about it. my mom and i joke she should give me some of her poop (i have ibs-c, autism, adhd, ocd, arthritis. what a fun mix of issues that can link to a gut microbiome!) but lately my moms been having tummy troubles so maybe i should ask my cousin lol. i didnt realise a poop transplant could help other autoimmune conditions tho, i thought it was just IBD and IBS, the directly-poop issues. my aunt has ankylosing spondilitis (yes, we are a lucky family huh lmao. my gram also has crohns and a couple cousins have ulcerative colitis. my mom and cousin are so healthy compared to the rest of us).
It can improve people’s health, but we can’t make money from it. Y’all. What are we even doing at this point, why is everyone willing to accept widespread pain and suffering because a small segment of people is obsessed with hoarding money?
whoever becomes the champion of fecal transplants should be crowned the king of poop
So the doctor lied to ten people by saying you just ate sheet ! Aaaahahahah
Why is the coffee here so expensive?....You don't want to know lol.
Give your body lots of antioxidant foods to process. Antioxidants are anti-inflammatory and there are a host of inflammatory illnesses that plague the human body and brain. Some of the most anti-inflammatory foods are beans: red beans, black beans, lentils, pretty much anything that is colorful. The great thing about beans is they take a while to digest. I have found that if I have six or seven ounces of beans in the morning I can go six or seven hours without getting hungry again. For me, that's a big improvement. Before we start a whole bunch of jokes about flatulence let me say that if you are serious about adding beans to your diet plan on using Beano for 1 to 3 months. After that you really won't have problems. For me that's an indication that the beans I've added to my diet have in fact engineered a new biome. My gut bioreactor is working more efficiently with the beans and not producing the gas. I would say it has to be because I have more bacteria that are up to the job.
All this time we’ve been avoiding fecal matter. We should celebrate it!
"Magic brown bullet" the disappointed face I made. lol
Vegan poo ftw!
(Was there a mistake ~@7:10? Prevotella is associated with plant-based diets, anti-inflammatory and believed to be helpful not just with Parkinsons but also MS)
Can I pick an option that doesn’t involve somebody else’s poop?
And first comment lol
@@GPatch your comment is second
you're not gonna taste the poop when swallowing a capsule of dried poop.
And by the end of the video after seeing all the benefits, I’d say if I had to I’d rather it go in where it comes out rather than in where the food goes.. because no matter what you do you can’t clean it enough because you want the bacteria in it. So I just rather not have to taste that if I didn’t have to.
What about your poop ? would it help if it technically came from your body 😂?
well, I drink the city water... so I already kinda do!
Well that’s a crappy solution
Secretin by IV in 1999, among two dozen kids in our autism school, about one third had dramatic improvements that lasted, about a third had temporary improvements that dissapaited over time, and the remaining third had no change. Then we could not get secretin in those dosages or providers willing to do IV infusions on kids ages 3-10, so it is was a small group single "study"
*Dissipated.
Ok that’s a lot of info, but my mind started drifting off imagining how there’s a scientist out there shoving human poop into mice… for science. “How was your day dear?”
Maybe that's why your dog likes to eat it so much
I'm convinced that along with selecting for more amylase production, when domestication of dogs happened, their sense of what tastes good was chucked down the drain. Dogs just eat SO many things that don't have any resemblance to food - I remain unconvinced that they truly know what food is.
I knew it! I was put on a drug for my back pain. The thing I really noticed was that I didn't seem to experience my misophonia while I was on it. The name of that drug suggested to me it had something to do with gaba or the job gaba would normally do.
8:52 that is NOT Parkinson 😂
It may sound crazy but a French kiss may be a way to share our biodiversity ?
Kissing in general already is. It's how kids get a lot of theirs from their parents lol
It's a great way to catch cavities too.
@@anthonywroblewski1802 there’s many ways to exchange bugs ….
@@anthonywroblewski1802 there is many ways to share our bugs …
@@anthonywroblewski1802 Cavities aren't contagious. Unless you think the bacteria that causes them has to be caught from somewhere else first. I don't think it works that way. Interesting idea, though. Might go some way toward explaining why I don't have a lot of cavities--I don't kiss people. LOL
The saddest thing about all these researchers/research is that it will be defunded in the current administration
It's been known since the 1950's in the US. Can't blame just one crackpot for 70 years of neglect.
It feels like this gets dangerously close to “panacea” land. I get suspicious of things that claim to be good for everything.
Kind of like how every CHD marketer claims to be good for everything every human has ever suffered.
What about the panacea of diseases caused by some inflammatory substances?
It works both ways occasionally.
I've heard about this for years-- when can we try it? 🥺 I'm so ill im ready to try it.
Can it be made into a pill
Yes, that has been done, in at least one FDA approved pill, as well as others in trials or elsewhere in the world.
This is one situation where less accurate labeling would be preferred.
“James butler, august 22 2024, morning after breakfast, 1lb 2oz”
But is the change permanent?
It might not be, at first. You have to establish a large enough colony to be self-sustaining. So, it might require multiple treatments to establish a permanent colony.
When can I expect ads from the Red Cross for a local poop drive? I don't think there's a shortage yet, but it's best to be prepared.
I like you using meeples in your infographics
The doo doo poo poo for you you... Cmon sci poetry
I wish it also fixed chronic rhinitis, antihistamines and even a turbine reduction hasn't fixed mine completely 😭
It's really simple why this kind of thing is good about treating health problems. Bacteria produce the chemical parts and processes that your body needs to function. Having them living inside you naturally produces the chemicals cheaply over time as well as processing other machines and chemicals in your body in ways that keep you healthy. Taking medicine has a huge drawback by comparison. Bacteria will cure diseases that we don't even know we have. I always wonder why so much focus on bacteria that produce bad reactions in humans are given more scrutiny than the ones that do good. It's just like social media.
It'd be interesting to see a comparison between fecal transplants and just eating your 30 different veggies per week.
The spice, he knows about the spiccccce.
This is it, the most cursed hank intro
SciShow video that starts off "would you rather" oh boy
My lunch has been enhanced
SOUTH PARK PREDICTED THIS!!
Another good reason why we shouldn't gobble antibiotics, unless it is really needed.
I think we know more about the brain than we do the link between health and internal bacteria.