Antiviral Pharmacology

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  • Опубліковано 6 лип 2024
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

КОМЕНТАРІ • 98

  • @Lucky-ff9pd
    @Lucky-ff9pd 4 роки тому +248

    The voices of med school I've become very attached to: Dr. Sattar, Dr. Ryan, Sketchy Micro guy, and Dirty USMLE

  • @professorkhan5315
    @professorkhan5315 4 роки тому +47

    Really great video!! I wanna add that a major differentiating factor between Foscarnet and Cidofovir is that Foscarnet has a seizure risk (I just think of S for seizure)

  • @redache467
    @redache467 4 роки тому +48

    -previr = protease
    -buvir = 5B RNA bolymerase
    -asvir = 5A

  • @alitantawy2222
    @alitantawy2222 2 роки тому +11

    one way to remember the hep c drugs :
    -If it ends with "previr" like "previous" so think NS3/4A , also starts with p as in protease .
    -" ASVIR " like after and starts with an A so think "NS5A"
    -"BUVIR" starts with b so think "NS5B"

  • @user-ul2sd8yc3g
    @user-ul2sd8yc3g 3 роки тому +34

    As usual, Great video
    One note , i think that viral thymidine kinase adds only one phosphate to some of the anti-herpetic drugs ( acyclovir , valacyclovir and famciclovir as I remember) and the other 2 phosphate groups are added by cellular kinases, not the viral one

  • @obadadaher4851
    @obadadaher4851 2 роки тому +15

    give CIDofovir with probeneCID

  • @IG-qv6sh
    @IG-qv6sh 3 роки тому +6

    I'm waiting for part 2 of it. This was the most helpful thing in my learning antivirals

  • @Umir445566
    @Umir445566 4 роки тому +31

    Thank you so much dude You are a legend. Any chance we can get a signaling mechanisms videos for hormones?

  • @akinolarukayat6475
    @akinolarukayat6475 2 роки тому +2

    Have had trouble remembering and understanding these drugs. You made it easier to assimilate. Thank you

  • @brookeanderson2631
    @brookeanderson2631 Рік тому

    Love the way you come up with tips and tricks to remember names and mechanism of action. Thanks!

  • @latifullah8574
    @latifullah8574 3 роки тому +5

    You made it so easy and I am waiting eagerly for HIV anti vitals. Thanks for helping us

  • @SG-gw5xo
    @SG-gw5xo 2 роки тому

    Thank you so much for the video, you deserve 1 million subscribers!!!

  • @serellamadole
    @serellamadole 2 роки тому

    Great video! You made the material so easy to digest.

  • @Muuip
    @Muuip 4 роки тому

    Great summary!
    Very helpful! 👍

  • @saintsam7397
    @saintsam7397 2 роки тому +1

    THANKYOU FOR NEVER ADDING MUSIC TO YOUR GOLDEN VIDEOS.

  • @raulblancoazcuy8308
    @raulblancoazcuy8308 3 роки тому

    I loved your video. Thanks

  • @xxamulyaxx
    @xxamulyaxx 4 роки тому +1

    thanks mate...
    simple slides...
    love from INDIA.

  • @xaaboopinkly
    @xaaboopinkly 4 роки тому +3

    I really don’t know how to thank you!!!!!!

  • @4agus
    @4agus Рік тому

    Great video, so useful! you made it really easy. Thanks Dirty

  • @pallavighatnekar1653
    @pallavighatnekar1653 2 роки тому +2

    For cidofavir you can remember given IV saline as I V is in the name cidofa VI r. Thanks so much for your information Dirty Medicine.

  • @marianacostaR
    @marianacostaR 3 роки тому

    Very good!! As usual

  • @AnilKumar-lo5rn
    @AnilKumar-lo5rn 3 роки тому

    i watchd ur videos ovarion tumours very excellent sir....nice pneumonice.....its very help a lot for me

  • @ambersani6889
    @ambersani6889 3 роки тому

    Thank you, Sir... plz upload part 2 as well

  • @PowderChaser
    @PowderChaser 3 роки тому

    Another beautiful video!

  • @drswetaruparel
    @drswetaruparel 4 роки тому

    Very helpful !!! Thanks 👍

  • @wacomundo9599
    @wacomundo9599 Рік тому

    Dude, thanks so much! I’ve had to give avyclovir a handful of times in the ED and i never new the actual mechanism behind it.

  • @ddfelder2
    @ddfelder2 4 роки тому

    Thank you!

  • @junaidmushtaq9421
    @junaidmushtaq9421 3 роки тому

    Thank you so much.. This is high yield for board examinations and u made is easy for us.😍

  • @marine3144
    @marine3144 4 роки тому +2

    You just taught me better than my prof

  • @raghadraghad7976
    @raghadraghad7976 2 роки тому

    so helpful ! thanks a lot

  • @stephenharris-dr
    @stephenharris-dr 8 місяців тому

    8:23 - I think it is because of the purine ring structures in the drugs (Acyclovir, Valcyclovir and Famcyclovir). Anyway, your channel help me a lot during my preparation for MRCP part 1 and part 2 written exams. I really appreciate it. Thank you.

  • @mahnoor7726
    @mahnoor7726 Рік тому

    Love all of your videos 👌👌👌👌

  • @tijinmathew6478
    @tijinmathew6478 3 роки тому

    In hepatis C NS5B inhibitor which is a RNA -DEPENDENT RNA polymerase is supposed to block step n0 .3 right?

  • @drhoneybee973
    @drhoneybee973 2 роки тому

    Dirty med you are great👍👍..thank you for making things easy-peesy..by any chance we could get a vid on anti-microbials!!!

  • @luckymaisha
    @luckymaisha 4 роки тому +26

    Can you possibly do one on antibiotics/microbials? Love your videos by the way!!! Thanks so much for making them

  • @awesomepabla7061
    @awesomepabla7061 3 роки тому

    God bless you

  • @vinodalbuquerque2488
    @vinodalbuquerque2488 2 роки тому

    Sir plz explain on Lamuvidine HBV antivirals inhibitors.

  • @tinashealthbeautyworld8396
    @tinashealthbeautyworld8396 4 роки тому +4

    Can you also please do Molecular cell videos too? Thank you 🙏 so much in advance

  • @abdulmohsenalmutairi7102
    @abdulmohsenalmutairi7102 2 роки тому

    Thx 🙏

  • @Lucky-ff9pd
    @Lucky-ff9pd 4 роки тому +1

    Cellular enzymes add the 2nd and 3rd phosphate

  • @enginoengin1174
    @enginoengin1174 4 роки тому +3

    Part 2 pretty please 🤓🤓

  • @Greanestbean
    @Greanestbean 6 місяців тому

    Awesome

  • @bhatwasim2831
    @bhatwasim2831 3 роки тому +1

    Love from Kashmir

  • @emerecene
    @emerecene 10 місяців тому

    Can you do one about NSAIIs and Antibiotics? And I wonder why you didn't mention other Hepatitis types?

  • @pramodthapa2517
    @pramodthapa2517 4 роки тому +1

    desperately waiting Viral Hepatitis doc

  • @ramzarukia120
    @ramzarukia120 4 роки тому

    love it

  • @cayladoo_1
    @cayladoo_1 Рік тому

    u r amazing

  • @Lopakaracing
    @Lopakaracing Рік тому

    I can't find the JOIN button anywhere.

  • @mohamedmetwalli3064
    @mohamedmetwalli3064 2 роки тому

    awesome

  • @yashpawate1306
    @yashpawate1306 4 роки тому +3

    This is just in time for my Microbiology shelf exam. Thank you so much! Please upload the HIV drugs too before saturday!

  • @MedManiac1
    @MedManiac1 3 роки тому

    legend!🔥🔥

  • @kenmiguel2986
    @kenmiguel2986 3 роки тому

    Please do an HiV antiviral video

  • @crimzonart1269
    @crimzonart1269 3 роки тому +1

    Please upload video on floppy infant
    Regards
    Dr. Gawher

  • @nurulaliahrizal
    @nurulaliahrizal 4 роки тому +1

    You're an incredible teacher! Btw please do anti-HIV video.

  • @christopherpatrick6949
    @christopherpatrick6949 4 роки тому +9

    Dirty, the absolute worst topic to learn is pediatric developmental milestones. If you could make a video for that I would be eternally grateful.

  • @alih6953
    @alih6953 3 роки тому +1

    Great video mate amazing job! I think there is mis-spelling. It is Simeprevir

  • @monirafarah4391
    @monirafarah4391 3 місяці тому

    Is this for step 2 only? I heard him say step 2 and I’m studying for step 1?

    • @kenibe3507
      @kenibe3507 2 місяці тому

      You need to know this for step 1.

  • @PtolemyXVII
    @PtolemyXVII 4 роки тому

    Very interesting! However 1) the antivirals in the AMI group would also block exosomes- due to exosomes uptake of sialic acid, and therefore also affect exosomes' action on T-cells by inhibiting them. Wouldn't this be hugely problematic and compromise the immune system? 2) the antivirals in the cyclone group, wouldn't it also inhibit RNA polymerase in cardiac cells as well as other normal cells due to its inhibition of thyamine kinase? This would mean that normal cells wouldn't be able to replicate. Thoughts?

    • @Ifeany1
      @Ifeany1 3 роки тому

      the drugs are activate by the virus....the first phosphylation step, making it more specific to cells infected by the virus.

  • @usmleislife3396
    @usmleislife3396 4 роки тому +2

    Hey can u make video on biostat hypothesis alpha and beta errors confidence interval... it will be very helpful

    • @otto9875
      @otto9875 4 роки тому

      Search on here USMLE biostatistics. There’s a guy i think his names Dr. randy something who Dirty endorsed for his bio stats review. It’s good

  • @elsatkkful
    @elsatkkful 4 роки тому +7

    Hey Dirty! Thank you for your videos, I know you're working hard to bring us these videos. Could you please make a video on the high yield microbiology. Thank you

    • @DirtyMedicine
      @DirtyMedicine  4 роки тому +11

      It’s a huge topic of that I would need to break into several smaller videos

    • @aj7147
      @aj7147 4 роки тому +1

      @@DirtyMedicine pls make more and more pharma and immuno videos pleaseeee !you the besttt....pls open a blog too like medicoawesome

    • @christopherpatrick6949
      @christopherpatrick6949 4 роки тому +2

      This is what sketchy is for

  • @yasinozkul6590
    @yasinozkul6590 3 роки тому +1

    l-e-d-i-p-A-svir (5A)
    s-o-f-o-s-B-uvir (5B)

  • @mohammadadnan6374
    @mohammadadnan6374 3 роки тому

    U need to make your own course like pathoma or b@b

  • @Ruqaya_pearl
    @Ruqaya_pearl 4 роки тому +4

    I dont know why im here, i have a surgery exam!

  • @lichh64
    @lichh64 3 місяці тому

    I love u.

  • @missionvision99
    @missionvision99 9 місяців тому

    3:39 6:14 8:11 10:15 11:12 12:29 17:27 18:40 fo SSS carnet

  • @majidbashir7102
    @majidbashir7102 4 роки тому +1

    Hi sir.
    Isn't part 2 yet available,???
    Part 2 of this video Non HIV drugs ??

  • @lgchinadragon
    @lgchinadragon 3 місяці тому

    thymidine kinase, not thymididine kinase, which you keep on saying. I get this too with phenylalanine lol

  • @alhasanmd7305
    @alhasanmd7305 4 роки тому

    Pharmacology profs disliked this video

  • @coverton
    @coverton 2 роки тому

    Sofo5Buvir

  • @maryalex9316
    @maryalex9316 3 роки тому

    I just wanna express my gratitude to Dr.Ono on UA-cam for curing my HSV 1&2. God will bless you Dr Ono

  • @bobbyboygaming2157
    @bobbyboygaming2157 3 роки тому

    your video would be half as long and easier to watch if you didnt wast so much time saying "this is like so high yield" like every 5 seconds

  • @younaskhan7343
    @younaskhan7343 Рік тому

    For best pharmacology classes follow Dr Malik Nouman official