I'm slightly curious about graft vs. host. I thought that T cells need to develop from their own "home" bone marrow and mature in their own "home" thymus. Sure, if the graft is something like CD34 cells (don't know if that's done) or bone marrow, yes, I can see the graft cells having a footing and proliferating at least some in the host. But some other organ? How would graft t cells be able to mount an attack without having the support of their own thymus, etc.? A solid organ would only be bringing at least somewhat mature t cells, it seems. I'm probably misunderstanding something.
Hyperacute---not a type II hypersensitivity. It's "directly comparable to a type III hypersensitivity, in which immune-complex deposition causes complement activation within blood vessel walls." ---The Immune system, 3rd ed. Peter Parham
Following renal transplantation a patient develops high-grade fever with chills and cough productive of mucopurulent sputum. Chest radiograph shows foci of consolidation. Which bacterial infection would you most suspect in this patient? a. Staphylococcus aureus b. Klebsiella pneumoniae c. Pseudomonas d. Streptococcus pneumoniae e. Legionella pneumophilia
Hey my opinion is Pseudomonas aeruginosa. Why? I think you are taking care of an immune supress patient where he passed a lot of time in hospital so pseudomonas could fit as an hospital adquires bacteria. Also is it possible that can be the other ones that pneumonia. My opinion as medical student (that doesnt know much so far) your information is not enough you such provide more about the clinacal history of the patient.
Very nice "nut shellization" of the topic! Everybody wants to be a doctor but nobody wants to learn these complex-ass mechanisms :D
Thanks, very helpful! quick and concise. Perfect!
Excellent! I loved the graft vs host part - the human body is amazing!
This vid is just simply amazing, pretty much sums it up. thank you.
This is very helpfull thank you so much😢❤
Wait i just realised this video is 10 years ago, when i was 10 yo😅
Thank You :'( very helpful. This is the most simplified and concise explanation I have ever heard.
You are very helpful! And I love your voice ;)
Tq for sharing ur valuable knowledge with us.... ur just awesome .........loved ur videos so much
Great Videoo!!!
I'm slightly curious about graft vs. host. I thought that T cells need to develop from their own "home" bone marrow and mature in their own "home" thymus. Sure, if the graft is something like CD34 cells (don't know if that's done) or bone marrow, yes, I can see the graft cells having a footing and proliferating at least some in the host. But some other organ? How would graft t cells be able to mount an attack without having the support of their own thymus, etc.? A solid organ would only be bringing at least somewhat mature t cells, it seems. I'm probably misunderstanding something.
Thank you
That was super helpful. Thanks a lot! ❤
Exccellent video and explanations. Youre awesome!
Hyperacute---not a type II hypersensitivity. It's "directly comparable to a type III hypersensitivity, in which immune-complex deposition causes complement activation within blood vessel walls." ---The Immune system, 3rd ed. Peter Parham
+Matthew Kresca All the text books I've looked in say it's a type II hypersensitivity as well
thank you for an awesome video keep up the good work
Thank you! This was awesome!
Awesome!!!
Big like for your efforts :-)
Following renal transplantation a patient develops high-grade fever with
chills and cough productive of mucopurulent sputum. Chest radiograph
shows foci of consolidation. Which bacterial infection would you most
suspect in this patient?
a. Staphylococcus aureus
b. Klebsiella pneumoniae
c. Pseudomonas
d. Streptococcus pneumoniae
e. Legionella pneumophilia
Hey my opinion is Pseudomonas aeruginosa. Why? I think you are taking care of an immune supress patient where he passed a lot of time in hospital so pseudomonas could fit as an hospital adquires bacteria. Also is it possible that can be the other ones that pneumonia. My opinion as medical student (that doesnt know much so far) your information is not enough you such provide more about the clinacal history of the patient.
thank u miguel
Woah! That was fast and finest
Thank you so much sir!!!!
Nice video
great video! helped a lot.
well explained , god bless you
Thanks. That really helped clear it up and give me the basics.
very helpfulthanks a lot
if the rejection occurs within 2nd day,3rd day or anyday before a week what is that??is that hyperacute rejection??
anjana joshi no that's supercute rejection
That's acute,,,,after 24hrs to some weeks
Hyperacute is within 24hrs
thanks man!
thanks,was helpful
Which organs dont show graft vs host reaction
Thanks ❤
Super easy
its gud..but b more specific...tq
good one
thank you allllot
nice
need to explain more broadly n in simpler manner
Awesome!!!
Big like for your efforts :-)