How to determine the protein concentration with the BCA Protein Assay

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  • Опубліковано 17 лис 2024

КОМЕНТАРІ • 27

  • @Kuroirena
    @Kuroirena 9 місяців тому +7

    You just saved me from failing my lab report! thank you! I didn't grasp anything my prof was saying and this just made everything make sense

  • @ludovico_fusco
    @ludovico_fusco 2 роки тому +6

    EXACTLY the video I was searching for 😍
    You used the same procedure my lab professor used, but explained it 100x better. I didn't even undarstand it was a BCA test until I saw this video...

  • @cwkgochan4733
    @cwkgochan4733 11 місяців тому +2

    Thank you so much! I have no idea what was going on in BCA assay until I saw your video

  • @CR-uu1rr
    @CR-uu1rr Рік тому +1

    Amazing video 🤩 😢Very detailed clear exhaustive you have taken away all my doubts . Spectacular step by step. Thanks a lot

  • @shinigemiX
    @shinigemiX 5 місяців тому +1

    Exactly what I was looking for, thank you so much 🙏
    Amazing video 👍👍

  • @dhilipkumar9146
    @dhilipkumar9146 Місяць тому +1

    THANK YOU HENRIK

  • @SpartanAegis
    @SpartanAegis 2 роки тому +4

    An excellent video, concise with relevant detail too

  • @iontach9844
    @iontach9844 2 роки тому +4

    Thank you for an excellent and very detailed video. I have a question about when you mentioned extrapolating the data to work out the unknown protein concentration. Shouldn't you say interpolate instead of extrapolate as the concentration is being determined within the range of known protein concentrations from the standards based on their absorbance values and the absorbance value of the unknown protein sample? I really enjoy watching your videos.

  • @albertkuo562
    @albertkuo562 3 місяці тому +1

    this video literally save me ,thank u!

  • @gabrieledomingosjardim5358
    @gabrieledomingosjardim5358 25 днів тому +1

    But how do we calculate the concentration using the equation?

  • @chinenyeezeneche7838
    @chinenyeezeneche7838 Рік тому +2

    Thank you so much for the video. Your explanation was excellent.
    Please, does the linear curve indicate any meaning to the experiment?
    How do we calculate the protein concentration using the equation of the standard curve?

    • @henrikslab
      @henrikslab  Рік тому +2

      Hey, thanks for that! The linear curve is of meaning to the experiment. You plot the absorbance value for each of your standard concentrations (use microsoft excel for that). If you have plotted the curve, you can see the formula of that plotted curve (you need that to calculate your sample concentration). Now, you replace "y" with the absorbance value of your sample and calculate "x". This is your sample concentration.
      Best, Henrik

  • @sillygoose4532
    @sillygoose4532 2 роки тому +2

    Very good explanation!! By the way, did you do all the animation by yourself?!!

  • @sadpineapple4123
    @sadpineapple4123 2 роки тому +3

    Gut gemacht mann!

  • @TheFlia
    @TheFlia 2 роки тому +3

    Thanks for this informing video. I have a question. After getting the concentrations (I am getting them in ug/mL unit) should I have to divide to 20? Because I am taking 200uL from the working buffer and putting 10uL of the sample. In the end, should I divide to 20 or multiply it by 20?

    • @henrikslab
      @henrikslab  2 роки тому

      If the device/program is not calculating the concentration itself, you would have to multiply by 20. But read into your device/program since many programs are calculating this already :)

    • @rrandaa1
      @rrandaa1 Рік тому

      Maybe a weird question but what number at the end is needed to be multiplied by 20 and why? Trying to myself understand how to get results to mg of protein.

  • @lovelyking9197
    @lovelyking9197 Місяць тому

    I wanna ask that I have a sample in powder form, so how do I convert it into liquid?

  • @misakostic2524
    @misakostic2524 Рік тому +1

    I am doing CSF prot.conc. and it is said to be 350µg/ml (micrograms per milliliter). This standard curve do not work so I am thinking to create 800/400/200/100/50µg/mL which is 10x more sensitive. Any thoughts if this will work at all?

    • @henrikslab
      @henrikslab  Рік тому +1

      Can´t tell, I would suggest to try it out and look at the standard curve!

  • @unknownbeliever4660
    @unknownbeliever4660 Рік тому +1

    Awesome man

  • @antimatter31
    @antimatter31 2 роки тому +2

    What part of Germany are you from?

    • @henrikslab
      @henrikslab  2 роки тому +1

      The area where I am from is called Ruhr area (german: Ruhrgebiet)

  • @openyourmind...
    @openyourmind... 2 роки тому

    Why 37 °C for 30 min ??? I believe that is not sufficient ...

  • @PoeJanice
    @PoeJanice 2 місяці тому

    Rodriguez Christopher Robinson Jason White Gary