6:00 Before adding the Grignard reagent, if we conjugate the two double bonds wouldn’t it be easier? MgBr still attacks on the O- ion and forms OH and the methyl group attaches to the +ve charge on meta position.
Gilman reagents can undergo both addition and nucleophilic reactions. In the case of alpha, beta unsaturated ketones, it's (conjugate) addition. For alkyl halides, it's a carbon-carbon-making SN2 reaction
Final Exams and Video Playlists: www.video-tutor.net/
Full-Length Math & Science Videos: www.patreon.com/mathsciencetutor/collections
Whenever I see you've made a video about one of the lectures in my class I feel an overwhelming sense of serenity peace and safety
You should be nominated for the nobel prize
Thanks you are the best tutor on youtube.
THANK YOU FOR SAVING ME!!!!!!❤❤ AND THANK YOU FOR TEACHING BETTER THAN THE SCHOOL TEACHERS
Thanks for the example at the end, that was really helpful for understanding the point of Gilman
Bro this is underrated video, its an AIEEE 2005 question :)
Thnx really helped for my grade 12 exams
Like your videos. Love from india😘😘😘😊🤗
I am also from india for which are you preparining
@@ashokchoudhary4709 I know you came here after solving ms chouhan Grignard reagent chapter
@@nevermind4329 woow
@@ashokchoudhary4709 jee advanced 2024
6:00
Before adding the Grignard reagent, if we conjugate the two double bonds wouldn’t it be easier?
MgBr still attacks on the O- ion and forms OH and the methyl group attaches to the +ve charge on meta position.
The sole reason i am passing OChem right here
Thank you once again.
Is this topic (the gilman reagent) a very popular question on the PCAT?
Haha Gilman reagent the same week we mention them
First exam next Tuesday 👌🏾
Last question was helpful
You're amazing 👌❤️
Sick!! But wheres the mechanism dawg? Is this a metal mediated thing? Association? Reductive elimination?? Whats going on my dude?
Underrated
How is it that Gilman reagents can replace halides on sp2 hybrodized carbons (seeing as that can't happen w/ the SN2 mechanism). Is this mech not SN2?
Gilman reagents can undergo both addition and nucleophilic reactions. In the case of alpha, beta unsaturated ketones, it's (conjugate) addition. For alkyl halides, it's a carbon-carbon-making SN2 reaction
Amazing 👍👍👍
thank you
Do we really memorize all of this chemical reaction one by one??? is there any theory that makes sense for all of the reaction ????
But sir grignard also do 1-4 addition
Thanks
What’s a veno or aero halide
isnt a big part of gilman reagents that they can replace the Cl of a acid chloride
Yes, into a ketone, and it reacts no further.
show the curly arrows please
Hello does anyone know if it is possible to use (cyclopentyl)culi ?
please make more biology videos thanks