PROTEIN SYNTHESIS: A-level Biology. Transcription, translation and pre-mRNA modifications

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  • Опубліковано 7 чер 2024
  • Learn protein synthesis in this video for A-level Biology. Learn the process of transcription, what pre-mRNA and mRNA are, and the process of translation. I emphasise all the key marking points for the AQA exam board.
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КОМЕНТАРІ • 131

  • @adxm0382
    @adxm0382 3 роки тому +72

    Needed this, have my exam tomorrow. Another great video!

  • @epicfunnyvideos9289
    @epicfunnyvideos9289 Рік тому +4

    Thank you so much for your efforts the explanation is excellent and finally now i understood what is happening

  • @lara3024
    @lara3024 3 роки тому +15

    Great video! Everything’s explained really well, thank you!

  • @harrydonna90677
    @harrydonna90677 2 роки тому +2

    OH MY DAYYYYSSSS TY SM!!!! THIS HAS RLLY HELPEDXXXX

  • @daaragoodluck
    @daaragoodluck 3 роки тому +3

    Your Vids are Great!

  • @FriedaWilhelm
    @FriedaWilhelm 3 дні тому +1

    Thank you miss estruch

  • @danix6452
    @danix6452 3 роки тому +2

    Love this!!

  • @kayceelondon
    @kayceelondon 3 роки тому +3

    great video!

  • @javishulo3905
    @javishulo3905 3 роки тому

    THANK YOU!!!!! SO HELPFUL

  • @gobi9783
    @gobi9783 Рік тому

    Redoing my paper 1 mock from year 12 on thursday crazy how i learnt this in like 10 mins

  • @officialusherrunozivei
    @officialusherrunozivei 10 місяців тому

    Well explained I can't believe I understood today and I have my bio p2 exam tommorow

  • @tct5757
    @tct5757 25 днів тому +1

    So helpful

  • @BLACKWHITE-og3rg
    @BLACKWHITE-og3rg 6 місяців тому

    thank u tea cher for explaining love u

  • @ryou6453
    @ryou6453 4 місяці тому +1

    thanks!

  • @ajtv6208
    @ajtv6208 2 роки тому

    Have my exam on Wednesday, amazing vid

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому

      Good luck!!

    • @ajtv6208
      @ajtv6208 Рік тому

      @@MissEstruchBiology i did alot better using your videos thank you !!! my teacher recommended you

  • @reiwasaru
    @reiwasaru 6 місяців тому +2

    I actually understand it now wow

  • @domanidouglas9192
    @domanidouglas9192 3 роки тому +2

    I have my exam in an hour!! Thank UUU

  • @Nickuxx7
    @Nickuxx7 2 роки тому +1

    i dont understand why for your method you say dna helicase unwinds the double helix but in other videos rna polymerase is joined at the start and the hydrogen bonds are broken ?? which is right

  • @dannycartwright579
    @dannycartwright579 Рік тому

    Thank you

  • @Wojbes
    @Wojbes 18 днів тому +1

    you should have a beyond the spec section at the end for things beyond the spec but some people want to learn more i seen another channel do it

  • @mikrokosmos1652
    @mikrokosmos1652 Рік тому +2

    Your videos are so helpful for the IMAT too!
    After RNA polymerase joins the RNA bases with the complimentary DNA bases and pre-mRNA is created, what happens to the DNA strand that you took the bases from? Does it remain baseless? Or do the bases 'grow back'?
    Also since tRNA already has an amino acid attached to it, does this mean protein synthesis only refers to putting amino acids in the correct sequence to form a particular polypeptide?
    I used to think protein synthesis was the process of making an amino acid so I was a little confused.
    I'd be really grateful if you could clear this up for me since I have no base in biology.

    • @adailyfact
      @adailyfact Рік тому

      Good luck with the IMAT, hope you got into medical school!

  • @shannonharper2460
    @shannonharper2460 3 роки тому +5

    How much would you recommend the workbook? Is it full of exam style questions or more useful for the preliminary learning stage? Many thanks for all your videos!!

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +2

      Hey,
      Which workbook are you referring to?
      Glad you like the videos 😊

  • @whomer3197
    @whomer3197 3 роки тому +2

    Helpful video series! But doesn't rer do protein folding or do the Golgi and rear both do it?

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +1

      Hello,
      The main function of RER is to synthesise proteins as they have ribosomes. These proteins are then sent to the golgi to be processed and packaged.
      Hope that helps.

    • @whomer3197
      @whomer3197 3 роки тому

      @@MissEstruchBiology sorry, so rer does not do protein folding?

  • @esmmm990
    @esmmm990 Рік тому

    7:02 do we need to know the name of the enzyme for aqa

  • @destined0645
    @destined0645 9 місяців тому

    Please answer, some source state that it is RNA polymerase that does both unwinding and synthesis of the strand in transcription. But for DNA replication it is DNaA helicase . So it is RNA POLYMERASE that unwinds or helicase in transcription ?

    • @yoirfhmumfthtf
      @yoirfhmumfthtf 9 місяців тому

      DNA helicase unzips the DNA strand during DNA replication and it starts from the first hydrogen bond and travels to the end. But because the helicase enzyme can't 'see' where the specific genes it needs to unzip start(in transcription), RNA polymerase has to unzip the small sections of DNA instead as it knows where genes start and end. This is what my Biology teacher told me but it's better to just go with whatever your textbook says.

  • @user-vq4qy2hq5i
    @user-vq4qy2hq5i 4 місяці тому

    In the Spec (3.4.3) for AQA, it states 'Gene mutations involve a change in the base sequence of chromosomes. They can arise spontaneously during DNA replication and include base deletion and base substitution. Due to the degenerate nature of the genetic code, not all base substitutions cause a change in the sequence of encoded amino acids. Mutagenic agents can increase the rate of gene mutation.' Are we just supposed to know that this can happen, or the detail of what the substitutions and deletions do? Also, is there a video covering this?

  • @claudiaperretta6249
    @claudiaperretta6249 2 роки тому +3

    Hey, thanks for the vid! Is this still ok to revise from for the OCR exam board? Thank you!

  • @zariyahsaoirse5952
    @zariyahsaoirse5952 3 роки тому +1

    Isn’t DNA gyrase the one responsible for the unwinding of the DNA double helix, miss?

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому

      in reality there is more than one. For AQA, DNA helicase is all that students need.

    • @zariyahsaoirse5952
      @zariyahsaoirse5952 3 роки тому

      @@MissEstruchBiology I see, thanks miss!

  • @aaronrajimon312
    @aaronrajimon312 3 роки тому

    Hello, could we say free RNA nuclotides complantery pair with exposed base pairs or are we suppose to say free MRNA nuclotides???

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому

      hello,
      RNA nucleotides should be sufficient as long as you refer to the fact it is forming mRNA somewhere in your answer.

    • @aaronrajimon312
      @aaronrajimon312 3 роки тому +1

      @@MissEstruchBiology thank you

  • @DogeDogeriffic
    @DogeDogeriffic 2 роки тому +7

    Hello, I’m currently really tempted to buy your A-Level biology notes for topics 1-8 but it’s a tad bit pricey is it possible to get the 25% bursary discount despite not being on bursary?

  • @alevelphysics6606
    @alevelphysics6606 3 роки тому +2

    ❤️

  • @ibrahimmiah562
    @ibrahimmiah562 3 роки тому +3

    Is it not the enzyme rna polymerase which unwinds the helix?

    • @MissEstruchBiology
      @MissEstruchBiology  3 роки тому +4

      no, but the cgp textbook says that in error. Any enzyme that is a polymerase makes a polymer

    • @ibrahimmiah562
      @ibrahimmiah562 3 роки тому +2

      @@MissEstruchBiology oh ok thank you!

    • @aleezaahmed3947
      @aleezaahmed3947 3 роки тому +1

      i think gyrase enzyme is what unwinds the helix

  • @shahzarbukhlaw5963
    @shahzarbukhlaw5963 Рік тому

    I’m confused is it DNA helicase or RNA polymerase to break the hydrogen bonds at 3:35

    • @MissEstruchBiology
      @MissEstruchBiology  Рік тому

      DNA helicase breaks the H bonds

    • @lilyberchem
      @lilyberchem Рік тому +1

      Yeah DNA helices breaks the bonds, RNA polymerase makes the phosphodiester bonds -- I believe

  • @massacres2118
    @massacres2118 3 роки тому

    Legend you

  • @jencyauriavales4278
    @jencyauriavales4278 2 роки тому +3

    Hi, as your an experienced biology teacher, I wanted some advice..... I'm half way into yr 12 and I haven't made proper notes and have not consolidated content we have been taught. I have realised my mistake but I am wondering whether its too late to start as I know I want to do really well but I have also wasted half a year.
    Thank you so much

    • @freyaskuse6476
      @freyaskuse6476 2 роки тому +2

      Hi! I'm probably not the person you're hoping an answer from, but if you search up 'Biology with Olivia' on a website called TES, she has condensed notes available for free for the whole of year 12! I have made my own notes as well, but they should be useful to you as it would be difficult to make notes alongside learning the rest of year 12 content. I hope it helps :)

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому +5

      Hey,
      Definitely not too late.
      If you are after notes, I have the full AQA A level notes available here.
      missestruch.co.uk/product/a-level-aqa-biology-notes-full-set-topics-1-8-copy/
      These include all the theory for Y12 and Y13, highlight keywords and essay links for all topics. With these you won't need to make any extra notes, so instead you can focus on active revision strategies.
      Hope that helps 😁

    • @jencyauriavales4278
      @jencyauriavales4278 2 роки тому +1

      @@freyaskuse6476 heyyy!!!! Thank you sooo much...... you didn't even have to help me but you did which was very kind of you! I looked it up and now only topic 1 is free and I have to pay for 2,3 and 4 but nonetheless those topic 1 noted will be very helpful..... I was thinking the same thing on how I will manage to learn new content while making notes for old content. Are you doing biology a level at the moment or have you already finished?
      Thank you so much once again

    • @user.004
      @user.004 2 роки тому +4

      @@jencyauriavales4278 Hey I have her topics 1-4 notes, if you'd still like them? i can only send them as an email attachment though

    • @user.004
      @user.004 2 роки тому +1

      @@jencyauriavales4278 Hi, I can send them now if you'd like? And no problem x

  • @icysid7855
    @icysid7855 2 місяці тому

    this is RAD dawg yhhhh

  • @tomrackham693
    @tomrackham693 3 роки тому +3

    HERO

  • @ak-7865
    @ak-7865 2 роки тому +1

    2 amino acids delivered by tRNA ????? Isn't it one

    • @ak-7865
      @ak-7865 2 роки тому +1

      Also if u don't mind me asking aren't u meant to mention phosphodiester bonds forming in transcription pls respond😀

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому

      hello, two amino acids are delivered at a time by two different tRNA molecules.

    • @MissEstruchBiology
      @MissEstruchBiology  2 роки тому

      depends of the exam board. RNA polymerase joins adjacent RNA nucleotides together is the key marking point for AQA, but yes that is by phosphodiester bonds

  • @jkjfk9225
    @jkjfk9225 2 роки тому

    bro stop