Damn, really wish I would have found this channel in the beginning of my semester instead of the end. Oh well, useful for biochem 2 next semester! Thanks!
Thank you for this video. I was wondering about what the effects of too much CO2 and too little CO2 and the effects on the human body buffer system and BANG - This. Again, thank you for this video. It was excellent. Keep on with the great videos my good man.
Very thorough and helpful vid! The example to treat hyperventilation by using a paper bag is good for understanding but should never really be done (at least that's what i'm learning). If the hyperventilation/alkalosis is a result of overcompensation due to metabolic acidosis then giving the person a paper bag to breathe into could drop their pH dangerously low. Although, I suppose if the hyperventilation is definitely caused by anxiety then it could be useful.
If CO2 is increased and the equalibrium shifts to the right (producing more H+), then shouldn't bicarbonate also increase by the same rate? If so, then doesn't that result in no overall change in pH? as opposed to a lower pH?
@@V1P3r4 I think (but not 100%) on this: pH is literally just to do with [H+] (concentration). So regardless of negative ions present in a solution (and therefore overall charge), pH is only concerned with the concentration of free H+ in a solution. I could be wrong but hopefully not XD. I'm sure we will find out one day Filip! haha
@@hrperformance LOL, you're missing the point of your own the question--Shifting of that equilibrium from CO2 to H+ produces an equimolar amount of bicarb as well, so he's asking why wouldn't that simply buffer the H+ produced and thus have no net effect on pH. IOW why would increasing PCO2 produce acidosis at all??
NKSULLY.. I watch Khan Academy quite a bit, and though it's a similar sort of video Moofs voice is so different then Salman Khan's is. They are different people.
+NKSULLY Lol. There's no way you're serious. Sal Khan is the man and a person I look up to, and he, among others, inspired me to create this channel, but this video is absolutely not his. It's 100% mine. Every video on this channel was made by me.
So helpful. Thanks for all this. If possible, could you please make videos of med school subjects like anatomy, biochem, physio? It's hard finding lectures for those online.
I'm glad you found it helpful. I haven't made videos for anatomy and physiology, but I'm working on a medical biochemistry video course that can be found on courses.moofuniversity.com. Be sure to check that out!
Hey, sorry, but how come people actually develops acidosis after a while they are hyperventilating? Like in an asthma attack? I know they initially are alkalemic for the reason you explained, but from what I studies I know that they eventually develop acidosis and I really do not understand how this works!
Great video. But one thing bothers me: Hyperventilation: decrease of CO2 => decrease of H+ => increase of pH Similar for hypoventilation. That just doesn't make sense to me, since pH depends on [H+]
+Vitaly Borisov The pH can be calculated using [H+] which is the concentration of H+, namely pH= - log([H+]). Since it's a negative logarithm, the pH will be higher with a lower concentration and therefore increase if the concentration decreases.
can someone please for the love of god explain this to me.... i understand why increase CO2 would result in an overproduction of H+, however, does it not also result in an over production of bicarb? and wouldn't the 2 just cancel each other out since H is acidic and bicarb is alkaline?
In blood carbonic anhydrase is unavailable to catalyst conversion of proton and bicarb to carbonic acid.. The bicarbs by means of chloride shift is taken back by the rbcs so the co2 is exhaled out..hence neutralisation of h+ by bicarb can occur only in presence of CA which is not available in blood.. I think this is one of the reasons
Between acidosis and alkalosis , in general acidosis is by far the worse for our health. Therefore hyperventilating can have positive regulatory impacts on blood ph. You heard it hear first lol .
Brent Wheeler actually there is a ratio in our body between carbonic acid and carbonate ion, in healthy state a ratio of 1 part carbonic acid to 20 parts bicarbonate provide a noramal pH. so when co2 incresed the carbonic acid increses and to maintain the healty ratio the 20 bicarbonates used to neutrilize the effect of 1 carbonic acid and the H+ incresed and the pH goes down. If you want i can make u understand by a video.
@@anilmandiwal8467 Wow, that makes absolutely no sense. 1 mole of carbonic acid breaks down to 1 mole of H+ and 1 mole of bicarb. That's just basic chemistry. So from one mole of carbonic, how the hell does it take 20 moles of bicarb to buffer 1 mole of H+???
If a person is hyperventilating and is still conscious and able to follow commands you COACH them to breath normally. Never put a bag over their mouth.
If un damaged the respiratory centers of the brain will eventually take over. They may faint. But it will compensate. Unless there are other factors. But never occlude a person's airway!!!!!!
Damn, really wish I would have found this channel in the beginning of my semester instead of the end. Oh well, useful for biochem 2 next semester! Thanks!
This video was amazing, I had the hardest time with acid/base imbalances in nursing school and then watched this and totally got it...thank you!!!
Summer Shepherd Thank you for the kind words! I'm glad the video helped! :]
absolute legend this helped so much with my chem assignment!!!
Thank you for this video. I was wondering about what the effects of too much CO2 and too little CO2 and the effects on the human body buffer system and BANG - This. Again, thank you for this video. It was excellent. Keep on with the great videos my good man.
Very thorough and helpful vid! The example to treat hyperventilation by using a paper bag is good for understanding but should never really be done (at least that's what i'm learning). If the hyperventilation/alkalosis is a result of overcompensation due to metabolic acidosis then giving the person a paper bag to breathe into could drop their pH dangerously low. Although, I suppose if the hyperventilation is definitely caused by anxiety then it could be useful.
If CO2 is increased and the equalibrium shifts to the right (producing more H+), then shouldn't bicarbonate also increase by the same rate?
If so, then doesn't that result in no overall change in pH? as opposed to a lower pH?
Exactly my question! I am still looking for a response for like 2 days ago.
@@V1P3r4 I think (but not 100%) on this: pH is literally just to do with [H+] (concentration). So regardless of negative ions present in a solution (and therefore overall charge), pH is only concerned with the concentration of free H+ in a solution.
I could be wrong but hopefully not XD. I'm sure we will find out one day Filip! haha
@@hrperformance LOL, you're missing the point of your own the question--Shifting of that equilibrium from CO2 to H+ produces an equimolar amount of bicarb as well, so he's asking why wouldn't that simply buffer the H+ produced and thus have no net effect on pH. IOW why would increasing PCO2 produce acidosis at all??
Thank you so much, this is so so so helpful. especially before an exam!
Moof is da Truth!!!!
shout out to Khan academy for inspiring great videos like this!
+Andres Chavez Lol. Word! Big ups to Sal Khan and Khan Academy for sure! I've got mad respect for that dude and for what he's built.
what is the application or the tool used in this video
Yes, this was, infact, a fabulous video!
This has been extremely helpful.
Thank you for explaining this so well! I'm very grateful! Keep making great videos!
Joseph Veit Sure thing, dude!
+Moof University Now - I will point out you did not make this video. Do not take credit for Sal Khan's work...
NKSULLY.. I watch Khan Academy quite a bit, and though it's a similar sort of video Moofs voice is so different then Salman Khan's is. They are different people.
+NKSULLY Lol. There's no way you're serious. Sal Khan is the man and a person I look up to, and he, among others, inspired me to create this channel, but this video is absolutely not his. It's 100% mine. Every video on this channel was made by me.
+Joseph Veit Indeed - I am a different person. Lol.
thank you! I really needed this!
What about the Na element in this equation?
Thank you for explaining this✨
saved my life as well!! keep doing what you do!!
Thank you for your video. It is very clear and easy to understand. Very helpful.
MsJls143 You're very welcome! I'm happy you found it clear and helpful in getting you to understand.
So helpful. Thanks for all this. If possible, could you please make videos of med school subjects like anatomy, biochem, physio? It's hard finding lectures for those online.
I'm glad you found it helpful. I haven't made videos for anatomy and physiology, but I'm working on a medical biochemistry video course that can be found on courses.moofuniversity.com. Be sure to check that out!
excellent video!! Everything was explained in slow easy steps. Thanks a lot !
great video. You explained everything so clearly! tbh I never knew what people did for Hypoventilation... it's so obvious.
Just saved my life. Thank you!
Awesome! You're very welcome!
I'm very grateful for this video explanation
Thank you so much! You are a wonderful teacher!!
Hey, sorry, but how come people actually develops acidosis after a while they are hyperventilating? Like in an asthma attack? I know they initially are alkalemic for the reason you explained, but from what I studies I know that they eventually develop acidosis and I really do not understand how this works!
Ilaria Giudiceandrea I'm actually not sure about that. I'd have to look that up, but perhaps you can direct me to the source you're getting this from?
Wow thank you for this video sir
8:44
The range of normal pH is : 7.35-7.45
Thanks Moof!!
Great video. But one thing bothers me:
Hyperventilation: decrease of CO2 => decrease of H+ => increase of pH
Similar for hypoventilation. That just doesn't make sense to me, since pH depends on [H+]
+Vitaly Borisov The pH can be calculated using [H+] which is the concentration of H+, namely pH= - log([H+]). Since it's a negative logarithm, the pH will be higher with a lower concentration and therefore increase if the concentration decreases.
Nathalie B
Ah yeah. My bad. Got a bit confused. Makes total sense. [H+] goes down, [OH+] goes up and pH also goes up.
Thank you sooo much!!
This video helped me so much, Thank you!
very nice and clear video thanks
FLmanity You got it, dude!
Thanks so much form NSW Australia ...
can someone please for the love of god explain this to me....
i understand why increase CO2 would result in an overproduction of H+, however, does it not also result in an over production of bicarb? and wouldn't the 2 just cancel each other out since H is acidic and bicarb is alkaline?
In blood carbonic anhydrase is unavailable to catalyst conversion of proton and bicarb to carbonic acid.. The bicarbs by means of chloride shift is taken back by the rbcs so the co2 is exhaled out..hence neutralisation of h+ by bicarb can occur only in presence of CA which is not available in blood.. I think this is one of the reasons
Amazing, thank you!!!
Thank you. I get it!
Pretty good video, but all I could focus on after like half the video was how often you said "right, right, right",.... "right" lol
+Melanie M Lol. Everyone's got their quirks. I suppose that's one of mine.....right? Haha.
Moof University right....😂great video
Between acidosis and alkalosis , in general acidosis is by far the worse for our health. Therefore hyperventilating can have positive regulatory impacts on blood ph. You heard it hear first lol .
Thank you so much!
mathieu mcconaughey is teaching
New subscriber here. I have a chance at a better grade now. LOL Thank you.
right
But it's a very good explanation. I loved it.
Thank you :)
Basicosis! made me laugh =D thank you, you are great! =)
If u increase the CO2, u increase the H2CO3. Then u increase the H+. Won't u also increase the HCO3 ?????
Same question
I am confused
Brent Wheeler actually there is a ratio in our body between carbonic acid and carbonate ion, in healthy state a ratio of 1 part carbonic acid to 20 parts bicarbonate provide a noramal pH. so when co2 incresed the carbonic acid increses and to maintain the healty ratio the 20 bicarbonates used to neutrilize the effect of 1 carbonic acid and the H+ incresed and the pH goes down. If you want i can make u understand by a video.
@@anilmandiwal8467 Wow, that makes absolutely no sense. 1 mole of carbonic acid breaks down to 1 mole of H+ and 1 mole of bicarb. That's just basic chemistry. So from one mole of carbonic, how the hell does it take 20 moles of bicarb to buffer 1 mole of H+???
If a person is hyperventilating and is still conscious and able to follow commands you COACH them to breath normally. Never put a bag over their mouth.
Ahhh this is good, but soooo slow lol
BamBina RM 😂😂😂 you are right
Because if they can respond to commands they are not yet in true respiratory alkalosis. They just need to calm down.
If un damaged the respiratory centers of the brain will eventually take over. They may faint. But it will compensate. Unless there are other factors. But never occlude a person's airway!!!!!!
NO PAPER BAGS EVER
Please don't perpetuate old wives tales that can hurt people