The Binding of Isaac: Afterbirth+ - Synergy Lab: ULTIMATE DEMON BONE PORTAL!

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  • Опубліковано 31 гру 2024

КОМЕНТАРІ • 644

  • @remyzk9424
    @remyzk9424 7 років тому +75

    Wow, today I was thinking "man I wish there was a new synergy lab" rage have you finished your mind reading machine?

    • @chrishuisman2806
      @chrishuisman2806 7 років тому

      Rickstery i think he has........ well our privacy is screwed

    • @remyzk9424
      @remyzk9424 7 років тому +6

      chris huisman meh I think rage is too much of an incompetent villain to know what to do with it to create world domination

    • @user-mj8yx5tx3q
      @user-mj8yx5tx3q 7 років тому +1

      Rickstery yeah as long as he doesn't- oh ummm I'll shut up now..

    • @heheheiamasupahstardiogran7131
      @heheheiamasupahstardiogran7131 7 років тому

      BONES

    • @remyzk9424
      @remyzk9424 7 років тому +1

      Hadooking Productions he already knows what you were gonna say

  • @leoxesyude2021
    @leoxesyude2021 7 років тому +9

    9:25
    Rage, it's obvious! Isaac is Kimimaru from the Naruto Shippudden anime.
    *Both die at the end*.

  • @dragzking
    @dragzking 7 років тому +12

    little horns effect is what is killing the blocks, not your damage

  • @sirdoggydawg8600
    @sirdoggydawg8600 7 років тому +21

    If my initials were my evil villain name I would be "Orange Headed murderer" ... watch your back kids ima juice you .

    • @CloroxBleach-bn1by
      @CloroxBleach-bn1by 7 років тому

      Sir DoggyDAWG hott

    • @sirdoggydawg8600
      @sirdoggydawg8600 7 років тому

      Clorox Bleach U know ;)

    • @sirdoggydawg8600
      @sirdoggydawg8600 7 років тому

      Hadooking Productions or Super Jerk Squirrel

    • @CrazedKitsune
      @CrazedKitsune 7 років тому

      I am Calicifying Axe Baron, your death can be swift or agonizingly slow depending on how I choose to hack at you.

    • @wetsock6334
      @wetsock6334 7 років тому

      Sir DoggyDAWG mines it tria

  • @lunatheluma3804
    @lunatheluma3804 7 років тому +26

    Definitely bring back mod of the week if you want to it was a amazing series🙂

  • @SunkenEgo
    @SunkenEgo 7 років тому +5

    David Wiltner Menezes so.....
    Deadly winter menace
    Yeeeeee
    I like it

  • @fio9930
    @fio9930 7 років тому +33

    At least blood boobs don't exist in Isaac

    • @EmersonHacker
      @EmersonHacker 7 років тому +7

      Y E T

    • @jamierawson8979
      @jamierawson8979 7 років тому

      Fion Li. yet

    • @awillers55
      @awillers55 7 років тому +2

      Fion Li That's my new project. make a mod for Isaacs that has blood boobs

    • @sythrus
      @sythrus 7 років тому +3

      YOU HAD TO SAY IT

    • @Tachiiiiii
      @Tachiiiiii 7 років тому +2

      Fion Li thank the patrons for thst

  • @onyxdrawsoffical9399
    @onyxdrawsoffical9399 7 років тому +1

    Rage, you're an awesome youtuber, the synergy lab being very nice to watch. You're also amusing to listen to while I'm drawing.

  • @remyelle
    @remyelle 7 років тому

    Also Rage, in terms of finding Delirium's Boss Room, it has to fit on the map as a 2x2 room without touching any room but the entrance room, even though the map will only show a normal sized room. The only thing this really allows you to do is guarantee that some rooms are NOT the Delirium fight, but it's better than nothing

  • @heheheiamasupahstardiogran7131
    @heheheiamasupahstardiogran7131 7 років тому +5

    RATTLE ME BONES, RATTLE ME BONES, TAKE WHAT YE WILL BUT DONT RATTLE ME BONES

  • @lorraineslakinski5148
    @lorraineslakinski5148 7 років тому +10

    ummmm, rage are you able to make a whole entire synergie based around tiny planet?

  • @BIAKaboose
    @BIAKaboose 7 років тому

    In terms of finding Delirium, I believe that since it is a 2x2 room there has to be proper space for it to not connect to any room but one. For example the void layout that you got this run only one of the boss rooms in the bottom right would have been a viable spawn location because it would cause the rooms to touch if there was a 2x2 boss room in all but the very far corner one.

  • @nicholasmckelvey3823
    @nicholasmckelvey3823 7 років тому +5

    EYE do SEE the swarm of eyes Rage.

  • @shadydoctor9169
    @shadydoctor9169 7 років тому +44

    RAGE I HAVE A SOLUTION
    record the mmo rpg then you work and have fun at the same time so you can justifiably waste time on them and who cares what the therapist thinks because they no nothing

    • @williamwang4188
      @williamwang4188 7 років тому +1

      Shady Doctor therapists actually know a lot

    • @piculra7441
      @piculra7441 7 років тому +2

      They no nothing? So they yes everything?

    • @shadydoctor9169
      @shadydoctor9169 7 років тому +2

      piculra ummm yes I English
      but it could work as they just sit there saying yes and nodding and agreeing while making notes on how insane you are

    • @cloud_and_proud
      @cloud_and_proud 7 років тому

      The therapist is all in his head anyways.

    • @krisman0659
      @krisman0659 7 років тому

      Yeah

  • @SidnerTheNiceGuy
    @SidnerTheNiceGuy 7 років тому

    FYI the little horn item effect kills any none-boss enemies instantly and as such can kill immortal enemies such as spike blocks and stonies.

  • @malade3000
    @malade3000 7 років тому

    It's not because it's "So powerful" that you kill spike blocks, it's the black orb that turns tears into the quantum looking thing. Every non boss enemy dies in one hit no matter your damage, works with spike blocks, every enemy that can turn invincible(like the skeleton things) and the haunt's ghost before they are killable

  • @Zweyrohn
    @Zweyrohn 7 років тому

    delirium inhabits one set boss room, and it is a big one although not being displayed on the map, so because it can only have one entrance you can estimate where he is going to be.

  • @happycreepersdk
    @happycreepersdk 7 років тому

    7:40 "If you were an evil genius scientist type person. What would your name be?" Haha. I often what my name would be if i wasn't.

  • @alexdecarli2933
    @alexdecarli2933 7 років тому +1

    rage you should do a synergy lab where all you use are all the trinkets, trinket smelter, and mom's box for the bonus power boost for the trinket

  • @derpymuffin4504
    @derpymuffin4504 7 років тому

    Hey, Rage. I like your puns, and this was an AMAZING Synergy Lab™ buuuuut I got TIBIA honest with you I thought it looked more like you were drawing their life essence from them and absorbing it, but, whenever it passes over enemies, it's like a magnet and just takes their life essence with it. But man! There was no SKULLing around with this run. I mean, I'd love to see a FEMUR like it, I'd be FIBIA-ing to you if I said I didn't. Aaaanyway, I loved this synergy and would also like to see Mod Of The Week come back, but only ones you think are worthwhil, like you said. It would be SANS-ational if you saw this, but knowing my luck karma's gonna be VERTABRAE-ting me over the head. I'm absolutely BONE-d when it comes to luck. See ya!

  • @Blue_Carbon_
    @Blue_Carbon_ 7 років тому

    there is also a delirium hush which if u got the delirium item as Eden on greed mode you have a chance of having the hush as an ally doing the waves for you (and it can spawn charmed zombies)

  • @somdudewillson
    @somdudewillson 7 років тому

    FYI Rage, Little Horn is what's killing the spike blocks. It instakills anything with a health bar that's not a boss.

  • @heheheiamasupahstardiogran7131
    @heheheiamasupahstardiogran7131 7 років тому +7

    That's cocaine on the floor

  • @haljoa5165
    @haljoa5165 7 років тому +2

    Rage how have you not made a selfish synergy? With tiny planet, my reflection and other things that keep the stuff near you. And of course you need head of the keeper and soy milk with the trinket cancer.

  • @abhaysharma7919
    @abhaysharma7919 7 років тому

    I just have to thank you, Rage, for inspiring me to buy this game.
    Got Brimstone on my first run and killed Mom. I love it already.

  • @darkraimaster1293
    @darkraimaster1293 7 років тому

    Rage, for future reference it was not your damage that killed the invincible enemies, the void tear from little horn (the item) has the ability to do that if it hits them.
    Have a nice day!

  • @lmawo_2725
    @lmawo_2725 7 років тому +5

    How do I download this mod? I can't find it anywhere and I really would enjoy experiencing some of these synergies for myself

    • @xanderlopez6268
      @xanderlopez6268 7 років тому +2

      Branden Limauro ur not allowed to

    • @horesfan400
      @horesfan400 7 років тому

      Branden Limauro
      You can download other mods and use the console commands to create the synergy for yourself

  • @verareed9921
    @verareed9921 7 років тому

    This is just a great channel. It has great gameplay and the best commentary of any youtube channel.

  • @DJBaphomet
    @DJBaphomet 7 років тому

    Compound Fracture + Cricket's Head + The Parasite = infinite tears.

  • @gferrol118
    @gferrol118 7 років тому +1

    Rage, I've got a bone to pick with you. You were talking about insects then said "that's something that's always bugged me" how did you not mention the pun?!

  • @TarynBeeswax
    @TarynBeeswax 7 років тому

    The things in your muscles that push and contract... Rage, I'll give you a hint: That's EXACTLY WHAT THE MUSCLE DOES!!! Not what gives you strength, or what makes your arms puff out, but what gives you the ability to move...

  • @johnspiders
    @johnspiders 7 років тому +10

    my evil scientist name would be
    Crooked
    Impulsive
    Snake
    yea i dont know either

  • @Jackson-qe9dd
    @Jackson-qe9dd 7 років тому

    delirium becomes what ever bosses you've killed during that run

  • @TheOblivion5
    @TheOblivion5 7 років тому

    1. My youtube name is OmniTerra so taking the letters of that would suck.2. You have opened a portal into a dimension filled with beholders.3. I honestly did not expect to get a lesson on the difference between simian and human hand muscles. Although not in-appreciated.4. I wouldn't mind seeing the occasional Mod of the Week every now and then.5. Hah, bone puns. I find those humerus.

  • @OmGbRuBeN
    @OmGbRuBeN 7 років тому

    About the gorillas, were you thinking of tendons, while talking about their hand motion precision during the facts?

  • @Mackinz92
    @Mackinz92 7 років тому

    Rage, the Ark is completely impossible. The pyramids are just an example of modern day humans underestimating the ingenuity of older human societies.

  • @WhallexKing
    @WhallexKing 7 років тому

    10:36 Do you mean Joints?

  • @dragonfig6460
    @dragonfig6460 7 років тому +7

    3:24 by dogs u mean bitches cause bitches love the bone

    • @dragonfig6460
      @dragonfig6460 7 років тому +1

      It's 2017, should have seen that one coming

    • @alluviumboar
      @alluviumboar 7 років тому

      But is a bastard a male dog?

  • @awillers55
    @awillers55 7 років тому

    yes bring back mod of the week. In fact I am in the middle of creating a Greek mythology mod, which is an overhaul to the characters and items. it's not going to be an over powered mod, it's just to add a bit of variety to the game

  • @Anonymous-zv1ew
    @Anonymous-zv1ew 7 років тому +1

    this is one of the best videos you have made :-)

  • @chikendoodle1628
    @chikendoodle1628 7 років тому

    i feel like the bone isnt the main focus after a while and it turns into an eye of the belial thing. I was thinking for a bone that you have one huge bone you fire every so often and have extremely low shot speed

  • @Gimebooze19792
    @Gimebooze19792 7 років тому

    Watching yo throw us a bone. I've been thinking this whole time thinking that when they hit a wall or enemy they explode making me think the bone could be used to make a new fireworks synergy.

  • @FailedNorSeling
    @FailedNorSeling 7 років тому

    The Synergy is so powerful that it can kill Unkillable, Floating, Biting skulk heads

  • @buttersddragon
    @buttersddragon 7 років тому

    Rage, I'm pretty sure the Loki's horn effect kills things instantly including invincible things i.e. the spike block, so it wasn't your power doing that, it was just the spike block.
    Also, if you count my nickname, my evil villain name would be Juicy Bodacious Murderous Laxative.
    ... OKAY I WENT WITH THE FIRST WORDS THAT CAME TO MIND DON'T JUST ME

  • @gferrol118
    @gferrol118 7 років тому +1

    Man, you are boning a lot of enemies in this

  • @PR0CKBP
    @PR0CKBP 7 років тому

    what's up Rage! I've been watching for your videos since December I think. I love your binding of Isaac content.:) Can we get the info for your mod?

  • @edgelordj1419
    @edgelordj1419 7 років тому

    The destroying of the spike blocks is an effect of the little horn!

  • @ravingrabbid215
    @ravingrabbid215 7 років тому

    the word you were looking for at 10:38 ~ its tendon im pretty sure

  • @JDaGoat0713
    @JDaGoat0713 7 років тому

    Have you figured out what made that black cloud of tears from your first ab+ episode

  • @buttersddragon
    @buttersddragon 7 років тому

    Instead of Mod of the Week, you could do Mods of the Week, as many mods are just simple changes or with Afterbirth+ just an additional item, trinket, or sometimes a character. You could do multiple mods for each episode or you for characters you could do one per video (and I'd personally be more than okay with you using some of the characters and other mods for synergy lab especially one that I'm about to mention). For example, there's this one character mod that adds the character Mei who instead of firing tears has fires/tears surrounding her and circling her and she like extends the shape they rotate in in one direction. I haven't seen if this works, but if it does, she would work really well with this one mod that adds a tech 0 item that connects your tears with a tech beam.

  • @Smooshmoosh
    @Smooshmoosh 7 років тому

    There actually is a full scale replica of Noah's ark that was built near Lexington Kentucky in the United States

  • @Chris111294
    @Chris111294 7 років тому

    You somehow actually managed to kill one of the invincible Death's Faces at 17:51.

  • @flagrus7901
    @flagrus7901 7 років тому

    Have you tried using the smelter to absorb every trinket in the game? I wonder what that would result in... Would require a ton of batteries tho...

  • @alkatron768
    @alkatron768 7 років тому +2

    I'll call this synergy: BONETROUSLE

    • @chara7678
      @chara7678 7 років тому +2

      Alkatron I was waiting for the undertale comment :)

    • @chara7678
      @chara7678 7 років тому +1

      Alkatron I call it *A bad time*

  • @pistachio1293
    @pistachio1293 6 років тому

    Every time you hit an enemy, its severed flesh entices the swarm to rip off the flesh of any being for their master...

  • @GorlRoxy
    @GorlRoxy 7 років тому

    Actually, Rage, it's pretty much known now how the Egyptians built the pyramids. Well, at least, theories.

  • @blazeflamesthesilverfox9762
    @blazeflamesthesilverfox9762 7 років тому

    This makes me think that your actually absorbing the power of your enemies using the energy ball

  • @leecairnduff8021
    @leecairnduff8021 7 років тому

    Still surprised rage hasn't done an all companions run considering how much it's been reccomened

  • @milk3923
    @milk3923 7 років тому

    3 cool synergies
    1. All angel room items
    2.All devil room items
    3. All fimiliars

  • @talonhowe8131
    @talonhowe8131 7 років тому

    Toenail
    Maniacal
    Helicopter
    I'm imagining an insane guy on a helicopter throwing giant toenails as boomerangs.

  • @Swift_The_Leapzard
    @Swift_The_Leapzard 7 років тому

    The synergy makes it look link your extracting all the guts,blood and bone from whoever touches your death orb.

  • @blue3149
    @blue3149 7 років тому

    Little horn tear effect kills EVERYTHING (except bosses)

  • @whitelotus7457
    @whitelotus7457 7 років тому

    My evil initials name would be Tectonic Moon Maniac. I only do evil things when I can see the moon, and you'd better freaking hope there isn't a full moon out, or I'll release my tectonic trivia! and bore you with moon facts! COWER BEFORE MY POWER

  • @aonodensetsu
    @aonodensetsu 7 років тому

    Tyrael:
    Totally
    Young,
    Reasonably
    Advanced,
    Electric
    Lion
    first thing that came to my mind, will need to tweak it

  • @Janokins
    @Janokins 7 років тому

    Tendons or ligaments, I forget which is which, one connects bone to muscle the other connects muscle to muscle I think.

  • @totallynotapuffball9119
    @totallynotapuffball9119 7 років тому

    I think having a supervillain like that would be awesome.

  • @birbinabasket
    @birbinabasket 7 років тому

    MORE MOD OF THE WEEK!
    There are sooo many good AB+ Mods :)
    also the portal uses the target as a host to spawn all of the demons, sucking the host dry :)

  • @AmbrosiaPoly-yolkEgg
    @AmbrosiaPoly-yolkEgg 7 років тому

    MRPJ - Mr. Pajamas does not seem all that intimidating for a evil genius name

  • @danlemongton7534
    @danlemongton7534 7 років тому

    I feel like afterbirth+ added fantastic items with a few good bosses and one good floor, while antibirth added fantastic bosses and floors with a few good items.

  • @cosaur7175
    @cosaur7175 7 років тому

    it's either a ligement or tendon. I think it's a tendon that connects muscle

  • @meekalmenors
    @meekalmenors 7 років тому

    0:16
    "Drag the mouse away from the X."
    I didn't know there was an X on the like button...

  • @shard20001
    @shard20001 7 років тому

    Delerium randomly picks any boss that you've fought in the run, so i think the only bosses it can't be are megasatan and ultra greed

  • @abbyandbenbrady1857
    @abbyandbenbrady1857 7 років тому

    at the end of the story god tells Noah he will never flood the earth again and if it ever rains so much that people think he will, he will create a rainbow which is supposed to represent god setting down his bow

  • @oslozombie1742
    @oslozombie1742 7 років тому +1

    Genious Of the Realy Derpy Norway!

  • @Xeroc_0
    @Xeroc_0 7 років тому

    Great synergy lab Rage. And, I was playing Rebirth on my phone and picked up experimental treatment, only to have it SHUFFLE ALL MY ONLY TWO HEALTH AWAY!!!
    So god damn triggered.

  • @CreatureChaos
    @CreatureChaos 7 років тому

    I have a synergy idea, maybe call it real dad, or perhaps the kings squire,
    Items:
    King baby
    Familiars that look like baby's or have their shape
    BFF
    Light crown
    And anything else you feel would fit

  • @ripgasbaron9716
    @ripgasbaron9716 7 років тому

    the truth is tha Little Horn (the item) kills EVERYTHING, including Stoneys, Spike Blocks, etc.

  • @mikeymaher147
    @mikeymaher147 7 років тому +5

    do a synergy with every new item

    • @gaspi8352
      @gaspi8352 7 років тому

      Mikey Maher he did already

    • @xanderlopez6268
      @xanderlopez6268 7 років тому

      gaspiLP no he did it before AB+

  • @charlottechambers139
    @charlottechambers139 7 років тому +2

    i would love to see what would happen if u picked up every item

    • @bookmarker2891
      @bookmarker2891 7 років тому

      cameron chambers already done

    • @Anonymous-zv1ew
      @Anonymous-zv1ew 7 років тому +1

      cameron chambers he has

    • @rhyno4152
      @rhyno4152 7 років тому +1

      Book Marker that was afterbirth though, not afterbirth+

  • @gferrol118
    @gferrol118 7 років тому

    That void thing is a bug. It doesn't happen for me, which means either they deliberately did it, and my game is bugged so I don't have to, or your game is bugged which makes you have to do it

  • @Tatousu
    @Tatousu 7 років тому

    Rage issac's arm has a bone coming out his shoulder so he a freak of nature

  • @juibly2967
    @juibly2967 7 років тому

    cool synergy lab idea:choose a pokemon and become it.
    marowak=bone tears+boomerang tears
    extra points for fashion 🤗

  • @demon1ckn1ght39
    @demon1ckn1ght39 7 років тому

    My dog actually loves watching his channel

  • @purpur5
    @purpur5 7 років тому

    The full story of Noah's Ark was: humans were corrupted, God decided to kill them all except for the only noble man that was Noah, and he told him to build an ark so that he, his family and all animals would survive and everyone else perish, so the humanity would be defined by a noble man, and not by, well, Kain and such.

  • @stachio4265
    @stachio4265 7 років тому +1

    My name would be Malevolent Alien X-rays, neat.

    • @und3adninja108
      @und3adninja108 7 років тому

      Major Spacecore i'm stupid invincible bitch

  • @anthonywarthen967
    @anthonywarthen967 7 років тому

    Little horn is what kills the spike blocks btw Rage

  • @TheguynamedT
    @TheguynamedT 7 років тому

    If i was an evil scientist my name would be Dr. Totally Nice Guy. Nobody will ever see through it.

  • @somethingsomething9017
    @somethingsomething9017 7 років тому

    Evil villain name, eh? Mine would be Señor Stabby. It's pretty obvious what crimes I'd commit.

  • @cark9418
    @cark9418 7 років тому

    If my initials were a evil doctor name it would be "Academic Electric Nuclear Cat", My quote is: Cam (come) nir (near) ma (me)......

  • @voicelessnameless5913
    @voicelessnameless5913 7 років тому

    10:30 They're called tendons Rage.

  • @nedbennett6786
    @nedbennett6786 7 років тому

    Rage, if you go to the righthand wall and then SNEAK over to the portal you can enter it. Gotta be all stealth like ;)

  • @Kronos3900
    @Kronos3900 7 років тому +1

    Rage can you try the five nights at mom achievement win 5 games in a row as 5 different people you will unlock super secret tinted rocks

  • @Phhase
    @Phhase 7 років тому

    Try: Conjoined Transformation, The Wiz, Dead Turnip, Cricket's Body, The Parasite, and Tractor Beam

  • @qijiasun45
    @qijiasun45 7 років тому

    It looks like you are draining the blood(eye of belial), soul(holy light), and bones of the enemies.

  • @GooberLP
    @GooberLP 7 років тому

    Do you think this mod will ever go public? Im sure some of your evil henc-*cough cough*... Lab assistants would love to help find synergies. :P

  • @jkljosh7392
    @jkljosh7392 7 років тому

    little horn can kill spike blocks,turrets and any other invisible entity

  • @WickedWinter
    @WickedWinter 7 років тому

    Where can I get the synergy lab mod? I'm sorry if this has been asked before but I searched the steam workshop and I couldn't find it.

  • @templehang4489
    @templehang4489 7 років тому

    *Grabs Soy Milk* "that wasn't entirely effective, and I don't know why."

  • @cpuvioletheart3789
    @cpuvioletheart3789 7 років тому

    "all of my eyes get brought to me" Rage, 2017

  • @livingchaosmatrix
    @livingchaosmatrix 7 років тому

    Our initials? Angry Malevolent Ostrich Raiser.