Peter, you described the "labeling" process to identify a coronavirus as beginning with injecting coronavirus into a mouse. How do you know you are injecting the mouse with a coronavirus?
Put simply, take the virus sample from a patient who has coronavirus. If it's a totally unknown virus, you can still do the mouse antibody generation. Then you can confirm that new samples have the same virus. If you want to compare the virus to other known viruses (like the class of viruses known as coronavirus), you do molecular biology to it. Some examples: Filter the sample for size and look for blobby shapes consistent with coronavirus (requires expertise). Then do a PCR test to confirm (requires primers generated from other coronaviruses). Then do deep sequencing to confirm (this is the new hotness, basically grind up a bunch of viruses and read out their genes all at once). Then do an antibody test from some other coronavirus to confirm. Based on all of that, the sample has coronavirus. Then proceed to make antibodies.
You failed to explain how you separate all of the coronavirus antibodies from all of the other antibodies that mouse has in its blood, you are trying to make stained coronavirus antibodies arent you? Or are you just making stained antibodies that will bind to any of pathogines the mouse has antibodies for already, im confused , im pretty sure that mouse has a lot more in its blood than just coronavirus antibodies and you are going to have to explain your process of extracting only coronavirus antibodies from the blood if thats what yoi plan on doing, please be thorough in your explaination.
It is a good sign that you ask doubts, questions. But , remember the topic is vast and many concepts get into answering your questions. and he cannot do ALL that in 6 minute video.
Not me specifically. These images are from other peoples' papers. But yes, coronaviruses have been studied for a long time. They just have not evolved into a famous pandemic until recently.
Recap my shallow orientation on viruses i been told on biology 80% of my dna are viruses origin, viruses were before us, they are dormant, they protect host plants, animals, humans, inducting regular clean authopagy, upgrade in antibodies and are integrate system to DNA. 🤔 just not even history adds up1931, the first electron microscope invented and mention of speric viruses 20nm to 50nm in human not sure in what? 1965 uk full papers in nature edited by maddox, naming even symptomps rest is so bonkers or get Sars/ mars racial or wirdo imagining from tech tem /sem grey alien to picasso corona art? Do they even have any colour?🤔
Peter, you described the "labeling" process to identify a coronavirus as beginning with injecting coronavirus into a mouse.
How do you know you are injecting the mouse with a coronavirus?
Put simply, take the virus sample from a patient who has coronavirus. If it's a totally unknown virus, you can still do the mouse antibody generation. Then you can confirm that new samples have the same virus. If you want to compare the virus to other known viruses (like the class of viruses known as coronavirus), you do molecular biology to it. Some examples: Filter the sample for size and look for blobby shapes consistent with coronavirus (requires expertise). Then do a PCR test to confirm (requires primers generated from other coronaviruses). Then do deep sequencing to confirm (this is the new hotness, basically grind up a bunch of viruses and read out their genes all at once). Then do an antibody test from some other coronavirus to confirm. Based on all of that, the sample has coronavirus. Then proceed to make antibodies.
labelling antibody is a new idea which i learned from this video.
Very knowledgeable guy with interesting content. Really enjoyed watching just wish the video was longer.
Glad you enjoyed it!
You failed to explain how you separate all of the coronavirus antibodies from all of the other antibodies that mouse has in its blood, you are trying to make stained coronavirus antibodies arent you? Or are you just making stained antibodies that will bind to any of pathogines the mouse has antibodies for already, im confused , im pretty sure that mouse has a lot more in its blood than just coronavirus antibodies and you are going to have to explain your process of extracting only coronavirus antibodies from the blood if thats what yoi plan on doing, please be thorough in your explaination.
It is a good sign that you ask doubts, questions. But , remember the topic is vast and many concepts get into answering your questions. and he cannot do ALL that in 6 minute video.
Thanx !
Interesting
So u imagined corona in 1991?
Not me specifically. These images are from other peoples' papers. But yes, coronaviruses have been studied for a long time. They just have not evolved into a famous pandemic until recently.
Recap my shallow orientation on viruses i been told on biology 80% of my dna are viruses origin, viruses were before us, they are dormant, they protect host plants, animals, humans, inducting regular clean authopagy, upgrade in antibodies and are integrate system to DNA. 🤔 just not even history adds up1931, the first electron microscope invented and mention of speric viruses 20nm to 50nm in human not sure in what? 1965 uk full papers in nature edited by maddox, naming even symptomps rest is so bonkers or get Sars/ mars racial or wirdo imagining from tech tem /sem grey alien to picasso corona art? Do they even have any colour?🤔