Ozempic's Metabolic Impact: What You Need To Know | Dr. Tyna & Mindpump 2360
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- Опубліковано 27 лип 2024
- 00:00 Intro
02:21 How she got into practice and how she got into the GLP-1 space.
10:41 Peptide vs a drug.
11:14 The dose matters.
15:36 The GLP-1 deficiency factors.
20:07 Running into the resistance wall.
22:11 The downstream effects of GLP-1s on our metabolism.
25:34 The musculoskeletal impacts of GLP-1s.
28:41 Breaking down the GLP-1 peptides.
32:06 The thickening.
34:46 A wonderful tool/opportunity for people to get their lives back.
37:44 Wiring the brain through the use of these neurogenerative peptides.
42:45 Who is the best candidate for this peptide?
45:00 Addressing the fears surrounding these GLP-1s.
56:50 Is supplementation more important when on GLP-1s?
58:00 Understanding the incentives of a compounding pharmacy.
1:02:41 Speculating on the smear campaign against GLP-1s.
1:08:51 Why we’re Pottenger's cats.
1:11:23 Be an example to your children.
1:16:09 Addressing the autoimmune crisis.
1:18:53 The importance of educating yourself and being proactive as a patient.
1:20:36 Strength training is NON-NEGOTIABLE!
1:23:21 Lessons learned from her mentor.
1:26:30 One tool in the toolbox.
1:28:08 Her favorite peptides.
1:30:03 This is a slow and low process.
1:31:21 Why losing weight is the easier part. Maintaining it is hard.
Related Links/Products Mentioned
Ozempic Uncovered Course
www.drtyna.com/ozempicuncovered
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Ozempic: A Weight Loss Miracle or Metabolic Menace? A Discussion with Dr. Tyna Moore & Calley Means
drhyman.com/blog/2024/04/17/p...
Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018
pubmed.ncbi.nlm.nih.gov/35798...
Adverse Effects of GLP-1 Receptor Agonists
www.ncbi.nlm.nih.gov/pmc/arti...
Evidence-Based Guideline for Adult Sedation, Pain Assessment, and Analgesia in a Low Resource Setting Intensive Care Unit: Review Article
www.ncbi.nlm.nih.gov/pmc/arti...
Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial
www.thelancet.com/journals/ec...
Mind Pump #2110: Ozempic The Miracle Fat Loss Peptide: The Truth With Dr. William Seeds
mindpumppodcast.com/2110-ozem...
Mind Pump #2187: Why Building Muscle Is More Important Than Losing Fat With Dr. Gabrielle Lyon
mindpumppodcast.com/2187-why-...
How Affordable Could Generic Ozempic Be? As Low as $5 a Month, Study Finds
www.healthline.com/health-new...
Pottenger's Cats: Early Epigenetics and Implications for Your Health
price-pottenger.org/blog/pott...
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Peptide World Congress - Seeds Scientific Research & Performance
peptideworldcongress.com/
Mind Pump Podcast - UA-cam
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Mind Pump Free Resources
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Featured Guest/People Mentioned
Dr. Tyna Moore (@drtyna) Instagram
Website
www.drtyna.com
The Dr. Tyna Show Podcast
app.searchie.io/hub/8AVo25GRrX/
Mark Hyman, M.D. (@drmarkhyman) Instagram
Layne Norton, Ph.D. (@biolayne) Instagram
Dr. William Seeds (@williamseedsmd) Instagram
Leonard Pastrana. Pharm D
ssrpinstitute.org/medical-fac...
Dr. Gabrielle Lyon (@drgabriellelyon) Instagram
Drew Canole (@drewcanole) Instagram
Lily Nichols RDN (@lilynicholsrdn) Instagram
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THIS is how you have a conversation about medical issues! They were respectful to one another, questioned one another respectfully, no rude interrupting or being overly emotional because one person wasn't able to dominate the conversation. I want to understand and this is helpful.
One of the best podcasts regarding this topic. Please bring Dr. Tyna back. I have been listening to her prodcast but with the guys thrown in the mix, i just enjoyed it more.
Dr. Tyna is the one that made me feel comfortable trying tirzepatide, and I appreciate her research so much! As a woman at 42 years old with a long history of hashimotos (diagnosed at 8 years old), it's been great for inflammation and brain fog so far. I'm also very muscular, but this extra fat since my age changes is horrible.
Compounded glp-1 semaglutide reversed anything negative for me. Everything you have mentioned I concur. It reversed Weight struggles yo-yo, severe memory loss, brain function improvement, mental health, obsessive thoughts about anything addictive including alcohol (,alcohol free since 2019), on-line shopping (,i was totally out of control), my real estate career is back on track and it saved me during a really rough menopause. I'm a different person. My body composition is also so different than past weight loss. Also, I've been self-dosing semaglutide only as needed.....micro dosing since August 2022 and my mindset is completely changed for the better. I am in the driver's seat. Semaglutide Compounded is a miracle. It's my way of being in control of my hormones.
Oh amd last month I had new bloodwork and it was in th3 words of my gyno....."Chef's kiss!" 👨🍳💋
Amazing! Would you mind sharing what a microdosing amount\time frame looks like?
Please let me know what a micro dose of oral pill is? TIA
Im 62 and I had to beg my doctor to give me ozempic, I am on the lowest dose I have high blood sugar type 2. I also find it hard to lose weight because of my back injuries, had three level fusion and a total knee replacement. But I am working with strengthening my muscles with band resistance. Thank you for all your important information, it really helped me. Thank you so much again. I am one week in. And I already lost 10lbs... Can't wait to see where this goes....
Be prepared for stalled weight loss. Your not gonna keep losing 10 lb per week. Make sure to eat protein so you don't lose all of the muscle you have left at 62..
Ten lbs in one week IS NOT healthy. I am on Mounjaro duemto being type 2 diabetic and I'm happy with 10 lbs lost so far in about two months of using it. If I exercised I could've lost more.
Depending on your bmi and fluid retention, 10 pounds may be a perfectly healthy first weeks loss, not always 2-4 pounds for everyone. Be mindful, lots of water and protein with body weight strength training. Enjoy!!
Why on gods earth would you do that. Find a real fix and not these false empty promises.
this is my first week and I have lost nothing but I will soldier on
Wow! Thank you Dr Tyna, for this fascinating and comprehensive and wide-ranging conversation. You are blowing the doors wide open for people to heal so many debilitating conditions. Thank you for being open and vulnerable about your own experiences. You're a badass!!
I need Dr. Tyna!!! Everything she was going thru I am right now! Working out daily, watching macros, and just like overnight 25 lbs
Dr. Tynan is amazing. I love her podcast, and bringing her to mind up is the perfect fit. This is a must-see episode for anyone on or thinking about going on glp1. I've been on mounjaro for 21 months and lost 185 lbs with 5 days of strength training n 45-minute daily walk. I was 480 lbs and currently at 295 lbs. Mounjaro has helped remove my joint pain and help heal my heart. I'm no longer taking blood pressure medication. My brain fog is gone. I feel like my brain is functioning, like when I was in my 20s. My A1C went from 6.9 to 5.1. All my blood tests are normal. Getting my health back, I also discovered my testosterone was 250 and now on trt. I feel amazing and blessed.
Congratulations on your journey! What diet were/are you following?
@mistydaniels3163 prioritize protein. 1g of protein per ideal body weight. My goal 250g a day of protein.
Love Dr. Tyna I am currently on Semi and she speaks truth. I have not moved up from .25 due to listening to her and luckily my pcp agrees as long as I feel good we can stay slow and low. I am 7 weeks in and really no need to move up!
What dose r u using . Do u cycle . Trying to find a starting point to talk to doc with
I love Dr. Tyna!! Such a brave and informed woman. Her findings have only confirmed my personal experience with GLP1. The benefits are more than weight loss. I’m so glad you guys brought her onto the show. ❤
I give you five stars even 10 stars for your knowledge. It is so refreshing to hear someone who really knows what they’re talking about. I am 67 and still in very good shape out three times a week. Wait not a lot of cardio. Thank you for all your advice Pam.
Adam mentioned Dr. Tyna a few weeks ago and I have been binging her ever since. One of the things I love about your show…your mindful choices in guests and then I get to learn more from them. Great interview! Thank you!
I'm so happy you got Dr. Tyna... I just discovered her over the weekend and did a deep dive into her podcasts about GLP-1's and was thinking she'd be a great guest on your show! Then I woke up this morning to check out what new episodes you had and there she was! Great guest, reports the facts. LOVE. Also - love your show.
I was watching an interview with Dr. Tyna on this topic for the first time literally as you were posting this video. Afterwards, saw that you had posted and, skrrrt, here I am.
Dr. Tyna is amazing! So happy you guys had her on! As with most issues, it's never black and white. We should use every tool available to help people, and we should do it wisely!!👏👏👏👏
So helpful. Answered so many of my questions. Mind Pump has the best guests and does interviews better than anyone else!
She is wonderful, thank you for having her!!
Listening to Dr. Tyna is what started me on my path with microdosing semaglutide with a functional medicine doctor. Looking forward to seeing how this will help my inflammatory health issues.
Really enjoying this episode... I need to find Dr Tyna's podcast as soon as I finish watching.
I love Dr. Tyna And your show. I’m 65 losing weight and building muscle… I feel great for the first time in 25 years.
Dr Tyna Rocks! I want her for my doctor!
Thanks SO much guys! Dr Tyna is AWESOME!!! Great conversation!!!
Thank you for introducing Dr Tyna. Great interview! Thanks guys 💪
My 12 year old plays rec soccer. Parents still see the need to set up a snack schedule for games where everyone brings cookies, Gatorade and chips. I refuse to participate. I don’t see how refueling after a sporting event with toxic “food” is beneficial.
What happened to the oranges
Such an important conversation!! Thank you for this nuanced take!
Thanks for having more content on this topic. A loved one is thinking about starting this treatment, so hearing more information on this is very helpful!
This is such an amazing discussion. I always love to hear Dr Tyna’s thoughts so very enlightening. And you guys inputs is making this episode more engaging and so much more interesting. We need another episode with her as a guest.
Thank you for covering this topic! I’ve been hearing so much about these peptides but it’s hard to know what’s the truth behind them and how they work! This explains it so clearly for those of us without a medical background!
it is absolutely amazing that you have her on
So excited about this episode!!!
Really enjoyed the episode. Thank you for the great information.
What a great podcast… I learned so much today. Dr Tyna is so informed and so easy to understand!
Glad to see Dr. Tyna on your show! Great conversation! I also discovered Dr. Tyna on that Dr. Hyman interview/debate. I had never heard the perspective she presented about peptides. Since that time, I’ve been listening to her podcasts where she discusses a number of other health related topics.
Great interview I loved hearing more from Dr Tyna after also watching the Dr Hyman conversation
Loved everything about this. I'm considering a GLP-1 for the healing properties and not for weight loss. I love everything you guys do. Thank you for always being so inspiring
What a brilliant lady! Thoroughly enjoyed listening to her explain something she is obviously very passionate about! Great sense of humour, too! :)
I got so excited when I saw that you interviewed Dr. Tyna. I also watched her interview on Dr. Hyman’s podcast. I am a Registered Dietitian and Personal Trainer and am diving deep into learning more about the semaglutides. I have been watching Mind Pump regularly and am interested trying one of your fitness/nutrition packages. Thank you for bringing Dr. Tyna on your show and for keeping my finger on the pulse for current health news.
Brenda, I am also educated in dietetics. I'm curious what your thoughts are on whether the standard American diet (no need to chew) could contribute to low GLP-1? My hypothesis is that chewing, or proper biomechanics of chewing and swallowing, stimulates release of GLP-1.
Love you guys! Very beneficial podcast
Loved, loved, loved this episode! As a T2 diabetic and currently on 5ml of Mounjaro I found this extremely helpful. I've been on this GLP1 for 2 months but strangely enough when I adjusted my diet and started walking, I also started lifting dumbbells. Recently made the shift from focusing on fat intake (Keto) to more protein. This episode definitely helped me content some of the dots. Thanks guys!
Much awaited topic!
Very enlightening! Fantastic Interview
I’ve been waiting for this interview! ✨👍🏽
You guys are awesome made my life less confusing and I made all the over-working out mistakes my whole life, with little results. I have always been a non meat/ fish/ chicken/ just carbs and cheese mainly...sad to say, but once I got your info of more protein and less processed, and little "time wise" workouts, but more often. Now I am seeing results, but I also had some current health issues, just before I discovered you guys. Now I'm on a much better path. Thank you for relating to me similar stories that describe me almost exactly in the way of popular mistakes.
Wishing everyone a blessed happy Father's Day praise God praying for everyone everyday God bless you all..
Fantastic interview, thank you! Love you guys! Just passed the NSCA CPT exam and your podcast totally helped me prepare. Would love to start training with the RGP bundle!!
OMG, great video... Sharing with all my family 🫶
So far interesting episode! I will need to listen to this twice for sure
I do love learning new things so I will be paying good attention like always because you guys rock
Thank God Adam is back!
Loved this conversation
Thanks for this. I got a lot from this interview!
I found Dr Tyna preaching deadlifting before the pandemic when I went on a keto/ carnivore/ weight training journey. And wow, I love this episode. I had no idea how much potential there is in these peptides. I’m very interested to learn more now, and thinking about trying GLPs myself.
Just an amazing conversation
What an awesome episode
Great podcast!!
I have several programs but not the RGB bundle so hopefully soon I’ll get it 😉 Thanks for the guest. I saw her on Chalene and since you support her, it means even more.
award winning episode 🥇
GLP1s got me to strength train and eat right. Period. Don’t waste these moments ❤
Dr TYna I’m so glad I found your station. So much good information. I’ve sent it to everyone. Have you found any information on CLL patients. Thank you
I love dr tyna she’s amazing ❤
Love all the information! I’m in Canada, I’m 45 yrs old going through perimenopause. I’m overall fit, strength training 5 days a week and eat a high protein diet. How would someone like me get this peptide? I’m not obese, don’t have diabetes. If I asked my doctor to be micro dosed she’s think I was crazy. Is there a way for someone who is healthy but wants to be healthier to get trizepitide? Please help a Canadian girl out 🙏🏻
I was wondering how Adam got it? Do you need a prescription? Or is that only for the name brand versions?
I'm not sure if it works the same in Canada but here your best bet is to find a Dr or health care provider that is able to prescribe meds but is also independent of medical conglomerates,
which here typically means you pay up front and health insurance is little to no help
Then the prescription is taken to a compounding pharmacy,
which means they prepare the medication in house customized to your specific needs!
I am in Canada, and we can buy it from Canadian stores. Biosynergen peptides and Cantides research peptides sell for research purposes. I am trying a low dose to reduce inflammation. So far it’s working and I lost weight too. Though I wasn’t looking to lose any weight. We have to pay for it ourselves.
@KaapiGlen0ra just curious...how much do you pay for the sake of comparison?
Did she really claim that "if caught early enough it can reverse type 1 diabetes "? As a 25 yr type 1 I've never heard this before and honestly don't believe it. From everything I was taught, once your pancreas shuts down it can never be restarted
Idk man I think early enough means before it shuts down if that’s the case that it won’t reactivate
I think she is referring to LADA which is a type of type one diabetes (also auto immune) that happens gradually over time. I was on it and it worked WONDERS I went from a 12.7 A1C to 6.5% and I was on the smallest dose.
I wish I could have followed through with increasing dose but my dr. Said if I want to get pregnant I can’t be on anything but metformin and insulin 😢
If Wegovy or Ozempic are going to help us to heal our bodies, I'm going for it. I am working with doctors and dieticians from Stanford now. I will start strength training and do this right. Yes, I have Wegovy. It's good to get the right information. Thank you😊
Wow- what a GREAT podcast!!!! Thank you SO much ❤
Amazing !
Ive been waiting for the interview. I've been following Dr. Tyna since standing her truth with the big C. Definitely considering a microdose as i have about 30 pounds to lose.
This was frickin' 🔥 🔥 💥💥💥
I totally agree with the thought of muscle marbling and water. I've been pre diabetic with high blood pressure for over a decade and went pure carnivore. Now, I was a PT and weight trained 15 years ago. Being on carnivore and weight training for 3 and half months I've lost 55 lbs. 20 of it was muscle and the rest was fat! But my strength has increased and my blood pressure has went back to normal.
I am very interested in ozempic but I've always wanted to do things "naturally". Very interesting podcast. I would love to be a guinea pig for the small doses Dr. Tyna is exploring!
Thank you! I am off glp-1 almost three weeks now. I am over insulin resistance, past insatiable cravings, , no longer have to have alcohol just because my friends are drinking, have gained discipline. But my joints are feeling stiff. I’m 68, post menopause. After my next Dexa I may look at a micro dose if my joints continue to feel stiff.
Dr Tyna is gangster. I discovered her during covid, she was one of the few sane and rational voices in regards to the hype around the vaccine, which hindsight has shown she was correct in her position. Love this crossover, great conversation and very informative!
I've been on semaglutide about 2 months, im 38. No to mention weight loss, but I just feel like I'm in my 20s again. I feel lighter, I think clear again, so much motivation it's amazing peptide!
Experimental only..I would like to try these peptides. How can I get glp1?
Loved this episode so much. I wish a dexa scan and weight lifting was a part of the Rx. Should be mandatory.
Omg!!!🔥🔥🔥🔥🔥 these guys are the real AVENGERS! Let’s take out BIG PHARMA 🖤🖤🖤
Thank you for all you do!
@Sarai0293 Winner! Please email: ann@mindpumpmedia.com with a screenshot of your youtube username, winning episode number, and the email address you would like the program under and we will get you hooked up!
I got emotional watching this… it caught me off guard… not sadness but like an exhale I didn’t know I was waiting on. Sheesh …
Thank you❤
Mounjaro has helped me so much Losing 95 lbs, I eat more whole and clean now, my A1C went from 6.0 to 5.1.
This is really interesting. I wasn't really aware of everything, outside of the weight loss, that this could affect. Really has me wondering about being able to heal my heart issues, relatives" fertility issues or my kids dairy allergy and/ or growth problems. How does one really go about finding a Dr that knows about everything related here?
7:35 - What does Dr. Tyna mean by the delivery? What Novo Nordisk and the others did is make the peptide survive for more than 2 minutes in the body. That's what they actually are charging for, that you only have to do it every week instead of every few minutes.
She’s insane ❤️
I would love to see some studies not only about GLP1 deficiency but GLP1 excess! I really believe this is a thing. I’m so thankful for the invention of these GLP1’s because finally people understand how I feel. I am never hungry. No hunger and no thirst. I get so full on half a sandwich that I can’t finish it. I also suffer from a lot of nausea for absolutely no reason. Although I’ll never have a weight problem I’m constantly fatigued. Hearing Adam’s experience with the GLP1 was exactly how I feel every day. It leaves me wondering if they could use my DNA to make stem cells for transplant into those with deficiencies. I always feel so bad for people who can’t stop eating. So many struggle with this and I have zero interest in food. Take my peptides!!! lol
Omg omg omg- “the thickening!!!!!!!!!!
The thickening!!!!!!!!!😂
I have Liver problems! Does GLP-1 GOP-1 what does this do to your liver? Thank you!
This is amazing!! Help please! How do I find a doctor near me who can work with me on this? I’m finding it hard to find a physician who thinks this way. They either dismiss me or want to do a hysterectomy! I’ve been searching for years for some solution like this!
Hello, reach out to your insurance. They can help you find a great doctor.
Around 30:39 is Dr. Tyna saying Semaglutide? I’m struggling with my craving to drink. When I do all of my gains from the day go out the window. I’d love to get ride of my hedonistic behavior. I’d like to try some of that peptide.
How does the average person get semaglutide prescribed without spending thousands a month?
Exactly. The cost 😮😭
250 monthly for me. Utah
@slackjef wow that's awesome! Is it thru you're regular Dr ?
I know Hims now has it
@thelonesquid7886 Thank you
Where do I find a practitioner that will prescribe a GLP1 if I’m not diabetic? I would love to try this for all of the other benefits, but I’m not Type II diabetic or obese.
I'm having trouble figuring out how to get prescribed for the plethora of "off label" uses, as most doctors see a "normal weight" individual with history of eating disorders as an undesirable candidate, failing to see the vast nuance.🙄 Maybe I'm missing something, but I don't hear anyone talking about how they are obtaining these GLP-1s so easily.
Find a health professional that believes in these types of meds. It is similar to a man who sees a traditional dr who says 400 testosterone is “normal”.
@@slackjef UPDATE: I placed my order through Transcend last Friday! You're right; GP is a no go.
@@meredithhoward3733 best of luck. I have lost a ton of bad weight and added a ton of good weight and these meds are a god send. I went from 40% body fat in May 2023 to 13.5% June 2024. I began lifting and it is now my life. Everything this podcast speaks to rings true to me.
Anyone mico dosing now if so age weight and starting dose? Curious 🧐
I’m SO confused and “annoyed” /frustrated with all this! From everything I’m hearing…sounds like we would all significantly benefit from these peptides. I know I would for so many reason - but how to we afford this - if we can’t get a subscription? It’s so hard to hear all the benefits of cycling this into a healthy lifestyle- but frustrating that it’s so out of reach.
You go online and buy it from a peptide place with third party testing.
What Vegas conference were they talking about, pls?
How come for those of us who may be around 25lbs overweight we can not get prescribed glp1,s? They are saying you must have bmi 27. For me BMI 26 I do have high blood pressure and am pre diabetic
Where can I get a low compound made for me?
Thank you guys for always bringing us great information! I love your show🙌🏼
Loved this, but can’t seem to find the answer to what “micro dosing” means? Can someone share actual dosages and would this mean daily droplet intake or still weekly?
In another interview she talked about starting at .1 and only going up to .25
But please don't rely on me! Check out her website. I think there's more info there.
@yensounta6501 I'm not qualified to give medical advice... just passing on what I remember her saying in passing. She also mentioned having a protocol available on her website. I haven't checked that out, but even if it I have to buy the info from her, I think having her expertise is worth it.
What wad the name of the doctor they mentioned in the podcast?
do you have a compoundeding pharmacy you recommend?
I’m on it for 8 weeks. Low dose no weight loss. I’m going up next week so I’m hoping to lose some weight. My blood sugar is better I’m down to one Metformin a day if needed.
My problem is now I’m having night mares. So I do think that ozempic does something to the brain. Never had nightmares ever. I’m hoping once my body adjusts … the nightmares stop.
Very interesting. I recently read that carbs inhibit GLP1 production and protein (not specific which) improves it. Assuming that is corrects, could it be a reson why some people have good health results on a Keto diet aside of weight loss?
It is generally important to really understand what is going on with these peptides and especially why many people are deficient in the first place.
A save guess is likely a lack of exercise and shitty nutrition. But what exactly is bad for your health and why seems to still be open, right?
Personally, I have some skin issues that have been really persistent and I'd be curious to try GLP1s, but it's only covered by insurance for diabetics and under strict rules. so I'd likely have to pay myself and I dont even know which one I'd need and how much.
Additionaly, the ideal conclusion would be to figure out how to fix these issues naturally or prevent them in the first place.
I guess it might come back to the classics: Exercise, healthy nutrition (what exactly is healthy?), sunlight, sleep, stress
So it sounds like this could help with the ails of menopause but I don’t understand how to try micro dosing. I do not need to lose weight (although if I gain just a little it becomes the “thick”, which I hate )and goes only to belly,and cannot afford the cost if not covered by insurance. And no doc would prescribe for me for weight loss because I am relatively lean.But based on your conversation I am doubting compounding pharmacies. can u be more clear on what to say to a doctor as far as microdosing? I have some gut issues and the brain implications are fascinating but how does the normal, unconnected person proceed to test all the premises discussed here