FERTILITY SPECIALIST APPOINTMENT | TREATMENT FOR NK CELLS & ALLOIMMUNE IMPLANTATION DYSFUNCTION
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- Опубліковано 10 лют 2025
- FERTILITY SPECIALIST APPOINTMENT | TREATMENT FOR NK CELLS & ALLOIMMUNE IMPLANTATION DYSFUNCTION
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Hello beautiful people!
Sorry it's taken me so long to get this video up!
Please see below link to the video I mentioned re immune dysfunction & how it could very well play a role in your unexplained infertility, recurrent miscarriage, recurrent failed IVF transfers, or secondary infertility etc, plus another video below that might make it a little easier to understand the basics of immunology. Both videos are from the Sher Fertility Clinic.
"Webinar - Geoffrey Sher, MD - Immunologic Causes of Infertility":
• Webinar - Geoffrey She...
"Understanding Immunology":
• Understanding Immunology
We have our second Lymphocyte Immunization Therapy, (LIT), treatment coming up next week, which means we'll have a 6 month window to make a baby & pray the treatment works for us! We're not yet sure on how soon we plan to transfer our frozen embryo, however we're currently thinking it'll either be March or April.
Thanks so much for watching! :)
Love, light & baby dust xo
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FIND US ON INSTAGRAM: / tim.celeste.x
FIND US ON FACEBOOK: / timandceleste
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TTC & LIFE UPDATE | SURPRISE PARTY & FIRST LIT TREATMENT EXPERIENCE FOR RECURRENT MISCARRIAGE
• TTC & LIFE UPDATE | SU...
DQ ALPHA GENE MATCH | LYMPHOCYTE IMMUNIZATION THERAPY FOR RECURRENT MISCARRIAGE & FAILED IVF
• DQ ALPHA GENE MATCH | ...
DQ ALPHA GENE RESULTS | EXPLANATION FOR RECURRENT MISCARRIAGE, IVF FAILURE & NK CELLS
• DQ ALPHA GENE RESULTS ...
LAPAROSCOPY SURGERY RECOVERY TIPS!
• LAPAROSCOPY SURGERY RE...
FERTILITY CLINIC DRAMAS | OBTAINING SURGICAL NOTES
• FERTILITY CLINIC DRAMA...
SHOCKING NEWS FOLLOWING LAPAROSCOPY SURGERY
• SHOCKING NEWS FOLLOWIN...
EMOTIONAL LIVE PREGNANCY TEST | IVF FET 8dp5dt
• EMOTIONAL LIVE PREGNAN...
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CONTACT US:
Email: tim.celeste.x@gmail.com
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Music by Epidemic Sound (www.epidemicsou...)
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OUR TTC BACKGROUND:
~ Married- May 2013
~ Conceived naturally after a couple months trying, ended in missed miscarriage at 9w4d- Oct 2014
~ D&C
~ Laparoscopy surgery after 1 unsuccessful year of TTC following first miscarriage- Nov 2015
~ Surgery revealed blocked tubes due to infection following D&C
~ Conceived naturally prior to starting IVF, ended in another missed miscarriage at 7w6d- Feb 2016
~ Another D&C
~ Conceived naturally again prior to starting IVF, ended in chemical pregnancy- March 2016
~ IVF #1- April 2016
~ Fresh embryo transfer ended in chemical pregnancy with 0 embryos frozen
~ IVF #2- June 2016
~ Fresh embryo transfer ended in chemical pregnancy with 1 embryo frozen
~ Conceived naturally, slow rising HCG & ended in blighted ovum- Sept 2016
~ Yet another D&C
~ FET #1, never happened as our 1 frozen embryo didn't survive the thawing process- Dec 2016
~ IVF #3- May 2017
~ FET #2- September 2017- Heartbreaking BFN with PGS normal embryo...
~ Another Laparoscopy & Hysteroscopy surgery- November 2017.... TUBES NO LONGER BLOCKED!
~ DQ Alpha gene partial match- unexplained infertility FINALLY explained!
~ Alloimmune Infertility
After 6 pregnancy losses, 9 surgeries, (including egg collections), & almost 4 years of receiving bad news after bad news, we are ready for this 'bad luck' to end & to finally hold our longed for rainbow baby in our arms.
I have this same hope & desire for all of my other TTC sisters! xx
"Be gentle with yourself. You are doing the best you can."
I am so fascinated by this LIT treatment! It’s so wonderful you have access to this! I am praying with all my heart that this is the solution for you and Tim! I can’t wait to see you with your beautiful little miracle rainbow baby Celeste! 💕🤞🏻🙏🏻🤞🏻🙏🏻🤞🏻💕 I’m so sorry about the rough time you guys have been having lately, I hope things start looking up soon 😊
It is fascinating & I do feel so lucky to have access to it! Thank you Krystal- you're always so lovely & supportive! Hope your beautiful baby girl is doing well!
I am so excited for you! I don't know what it was, but you brought tears of joy to my eyes. I see you pregnant in March and holding your precious little baby by Christmas. I just feel like this is finally your prayers being answered. Can't wait for the good news. Hugs ❤️
Oh you're so lovely- thank you so much for your kindness & positivity! xx
Crossing fingers and praying!! You are so amazing for continuing this journey after all that you have been through!!
Love Dr. Sher. I’ve learned so much from him! I’m going to watch the webinar you’ve linked just to better understand your situation! Love you ❤️
Me too! He's been great- so glad he did so many UA-cam videos! Helped thousands around the world xx
Hi Celeste, So glad you are getting answers and that you are going to try again..yay! This month I did immune suppression with prednisone and it worked,I also was on fragmin (blood thinner) just to cover everything by chance there is any clotting issue. Start the prednisone and see how you feel,maybe you might want to wait a month before transferring but always go with your gut💕 I went on prednisone on Day 1 and did my transfer the same month with one of my lower grade embryos ( BB) I only transferred one and so far 🤞 we are pregnant again. I go for my beta Monday..I will be 4 weeks. I wish all the best and I can keep you updated on how this pregnancy goes taking the prednisone if you like. You and Tim are both in my heart and thoughts❤️
You & Tim are so very strong and brave. I know in my heart you two will have you're rainbow baby very soon! Sending all of my love, prayers, and baby dust your way. Lots of love headed your way!
Hi Celeste I am on an immune suppressing protocol and I have been told I need to take the meds for two cycles before trying so my NK cells levels are low enough for a pregnancy to take place.
I am on hydroxychloroquine this time around and will also have intralipids from positive test and every 4 weeks to 16 weeks. I am also on baby asprin along with omega 3, D3 and pregnanvare prenatals. Again I have had to take these 2 months before trying again.
I am so glad that you found the LIT treatment. Also pleased to know it’s available in the UK. I would try this avenue if this next protocol fails for us.
Fingers crossed for you! I have a great feeling
Thanks for sharing your protocol! The reproductive immunologist I had a phone consult with following this video said I would need to be on steroids/immune suppressants for around 6 weeks prior to a transfer. So I guess around the 2 month mark sounds ideal. I discovered when watching the Dr Sher webinar, that people with alloimmune dysfunction need to be on intralpids for longer than those with an autoimmune problem. He said alloimmune patients need to be on intralipids up until the 24th week of pregnancy. It's interesting how the importance of duration differs between the two different immunological issues. Praying your immune suppressing protocol works for you!! Keep me posted- will be thinking of you
Tim and Celeste thank you so much. I will also be keeping you both in my thoughts. You are a very lovely and deserving couple.
It is all so interesting finding out about different protocols and how they work. I feel I have gained so much knowledge lately. .
Praying rainbows are coming our way
I just found your channel and am subscribing. You are such a beautiful person inside and out, and I just know you will get your thb very soon Celeste!
Oh you're so lovely- thank you! xx
Don’t feel ridiculous about getting opinions. I feel you’ve learned something whether good or not good . Praying for you and Tim 🤗✨
Crazy all that we go through! Your story is so inspiring and I’m learning so much watching you!! Jealous of your summer BTW! ☀️
Praying for peace & success! ❤️👶🏼👶🏼👶🏼
p.s.- on a totally different note, I finally realized who you look like. Gillian Anderson as Agent Scully in the X Files! 👽
Thank you for your lovely prayers! Oh yes- I do too! lol
I’m completely fascinated by this treatment and in awe of your extensive research - and determination. It shouldn’t be this hard but I just love your attitude and truly believe that you’ll be rewarded with a beautiful baby at the end of it. All the best to you and Tim. Love from South Africa 🇿🇦
You're right, it shouldn't be this hard, but I'm just so grateful for the resources I've had available to me as they've helped me reach this point of discovery. Thank you
Makes me think....("you should just relax and it will happen") Can you imagine if you had listened to that 'useful' advice, or if you had just listened to your Dr's?...(After all they went to medical school). You have done an amazing job researching and advocating for yourself and getting to the bottom of things.
You seem to have direction now.. and i love that
Light at the end of the tunnel. Looking forward as always to more updates xxx
I'm so happy things are ramping up! It may be that within a month you will be optimally suppressed. My guess is that peak level will last a few months and then begin slowly to decline until you hit that 6 month mark? I can see, if you are not sure, taking an extra month would probably be fine (just based on how you feel). Ultimately you don't want to have doubts about that because I'm guessing you want to eliminate that as a doubt (if things don't work). Also how nice would it be for it to just happen naturally! I already decided even before my surgery to take an extra cycle more than required before planning a transfer... I just don't want to wonder if I was fully healed if the embies don't implant. Ive totally watched most of Dr Sher's webinars (so amazing to have as resources) and my clinic is connected to his original practice.
Yeah I'd say the first few months would be the peak level- I need to find that out for sure, but it would make sense. If that is the case, perhaps it would be best to do our FET sooner rather than later. Yes, eliminating doubt as much as possible is so important! I probably would've done the same as you following surgery. Oh yes, aren't we lucky to have the resources we have online! xx
Journey to baby C's mom here. So grateful for Dr Sher and his lifelong journey in helping improve IVF outcomes. He helped my daughter in 2017 and we are now anxiously awaiting the arrival of my first grandchild. 🤰🌈 27 weeks gestation. God bless you!
Hello! Yes, your daughter is so lovely! I have thoroughly enjoyed following her journey & so happy she's finally expecting her little rainbow! Such a magical time for you all- you're going to have one much loved granddaughter on your hands! x
Sounds like things are moving in a positive direction! Looking forward to hearing what the immunologist said 🙂
I am glad you looked into Dr. Sheer i found his webinars very interesting
I cannot thank you enough for sharing these resources!
I always look forward to your videos, you’re one of the few infertility youtubers who has (unfortunately) had similar struggles as I have.
After my 5th loss, a loss of a PGS normal embryo, I’m strongly of the belief that I have some type of immune system disorder. I also have premature ovarian failure and the ones that I do have are chockful of imbalances and translocations. I’m 26 but my eggs are that of someone 20+ years older than me. Wondering if that’s immune related too.
You really have encouraged me to keep going, to be strong and to keep fighting! I’ve found a new RE who is more aggressive, and is open to reproductive immunology as a developing field.
I wish all the best for you and Tim, and I truly hope that LIT is it, and that your frozen embryo is healthy and strong and results in a healthy little one born around the end of the year!
I'm so sorry you've experienced similar struggles! Sounds like you have something immunological going like me too. I have read that immune issues can have a negative affect on egg quality. I'm so glad to read you've found a proactive & experienced sounding RE who has an open mind!
Thank you so much for your kind words :) Wishing you nothing but the best too! Please keep me posted on how you go with your new RE. Sending all love & many prayers your way! xo
Im praying this works for you i just stumbled across your video one day and i pray this works for you and your family
Thank you so so much for getting more women to see Dr Sher's webinar!!! I do not want others to suffer so much. Could you ask your consultant where in the UK LIT treatment is offered as in UK?? The various national fertility websites send me round and round to each other and none answer a basic question of where a treatment is available...they basically say contact all of therm in the UK after the run around. I would really really like to know. I am wondering whether if I tried embryo adoption would I need treatment. I think....and I spend much my time thinking that if I were you Celeste, I would try FET into healthy young (possibly not a relative) surrogate AND try naturally at the same time. Best video yet. Xxx
Such a great webinar! Thanks so much for sharing it with me!! I can try to find out where in the UK LIT is available. Sounds like it's been a struggle for you to find someone though! I don't think I'm at the point of going down the surrogacy path just yet. It's so challenging here in Victoria, with some pretty crazy laws. I'm not at all against it as an option for the future, but I'm just not ready to give up my hopes of being pregnant & staying pregnant. I want to at least give this treatment plan a go & pray it works.. xxx
Fingers crossed for you both good luck and baby dust ✨🌈🤞🏻👶🏼
A plan! Yes!!! Fingers crossed, love
Only difference i know between dexa and prednisone is.. dexa passes placenta barrier... so prednisone considered to be considerably safe. You can ask about Dhea and Melatonin CoQ10 and vit E to improve egg quality in case you consider natural or fresh ivf to
Reproductive immunologist. Mine in Sydney added that to me. With immune problems.. amino acid content also reduces so.. L' agenine also helps alot. Due to steroids bones get weak, so vit d is what specialist also added.
Ah ok, good to know! Thank you! I've been on Melatonin, Ubiquinol (CoQ10), vitamin E & D for almost a year now- started taking them a couple of months prior to my 3rd IVF stim cycle. Never heard of L'agenine, so I'll be sure to look that one up- thank you! :)
I am a patient of Dr. Sher. I am going to Las Vegas in May from
NYC for treatment. He did the HLA and HQ alpha panel on me and my Husband.. turns out we are an EXACT match for both genes. We are looking at alloimmunity in conjunction with Natural Killer Cells...i am devastated but it is so great to finally have answers....
Oh hun, I'm so sorry you've discovered you're an exact match for both genes.. You're definitely in the best hands though, so praying praying praying you achieve success when you go to Las Vegas in May! Please keep me posted! It is great to finally have answers- all we can do is hope the treatment will work! We will be sure to keep you & your husband in our prayers! xx
Celeste, Dexamethasone and Prednisone are doing the same. There is also Prednisolone which does‘t pass the placenta. The other two do. Maybe you ask your specialist about it.
I was under the impression Prednisone & Prednisolone were the same thing? Interesting- I'll have to look into that! Thank you :)
Your videos are very informative. Thank you.
I hope it works for you both! Why is your consultant suggesting a transfer in March? Is it because he wants to make sure you'd be 4 months or so pregnant and thinks the more pregnant you are, the less chance of miscarriage? If so, probably better to do the transfer first, then try naturally if that doesn't work. My clinic stopped offering embryo glue because the medical evidence was that outcomes were worse than without it. Also, your issue doesn't seem to be implantation, it seems to be a post-implantation issue that's causing your pregnancies not to continue, so not sure how embryo glue would help you? It sounds as if you're in the right track with the immunes - good luck!
Tim and Celeste's first child might well be a boy, as there was a study done some years ago, that I read, written in Sweden or Norway about secondary infertility involving recurrent miscarriage, where a much higher proportion of cases, the first surviving child was male, followed by recurrent miscarriages. My first and only surviving child is male, after two miscarriages, and followed by eight later miscarriages. You two have a better chance than I had to have more than one child, with the testing and knowledge you sought so hard for.
Praying for you 💛
If they suppress you well enough it's very possible you could fall pregnant naturally considering your surgery results. Did your doctor say how long through this process before you are suppressed to the level he feels you should be? Stay well during this time, catching a virus is your biggest threat at the moment. Doing this during the summer and not flu season is wise.
I am further down alloimmune/autoimmune recurrenmiscarriage journey...and time, than where you are, and you are closer to testing answers and diagnosis. Here is something to ponder, if I had a 12th natural conception I would go for LIT, steroids, blood thinners, intralipids until 24 weeks and progesterone pessaries (in UK if I can find LIT specialist). There are 3 other options. If I go for egg donation and husbands sperm would I have to go for full treatments as reaction to husbands alloimmune stuff is back where I have always been, just with less related younger egg. Surviving son's sperm and donor egg might bypass alloimmune problem and no treatment needed, if he had the magic gene combination (no treatment pregnancy, full term), also would be grandchild we would be equally related to! A 3rd option is totally unrelated embryo as might need no treatment. Any thoughts, as I value your thoughts. Maybe try all 3 options with and without treatments....life not long enough.
Celeste have you tried ENDOMETRIAL SCRATCH ? After my wife did it she finally conceived.
Molecular Human Reproduction Journal will have a scientific paper by Professor Evelyn Telfer, an Edinburgh University researcher (I live in Scotland) on maturing human eggs from immature ovarian tissue biopsied from 10 young cancer patients, where they got 87 follicles to mature and 9 good quality eggs. Exciting science, UK national news breaking story on Friday.
Another video! 😍
I hope you get the answers from the next consult.
Thank you :)
Hi Celeste please excuse the profile picture it’s of my son..
I have been trying for baby no 2 for 11 years and I actually have an autoimmune disorder which my specialist for that has said there can be difficulties with implantation!
I have seen multiple fertility specialists in Melbourne and have spent almost $100’s of thousands on treatment with very little help..
Please can you share with me You fertility specialist name and where they are based as I need to find someone who understands autoimmune and can help us
Thank you in advance
Kim
If you are both heterozygous for dqalfa, 25% of embryos will be purebred, 50% heterozygous, and 25% free of gene mutations by my thinking. This makes sense based on my results of ten losses, one was trisomy so not of concern. Nine losses, and one success...10% success rate, so maybe 75% odds against me, 25% chance of success....on top of regular loss risk...weak eggs, conditions, etc, so chances less than 25% for me. You have more hope with more and better treatments from earlier in your journey..
I really really hope this works for you. x
Have you ever had a mock transfer done?
No I haven't. I'm not even sure what's involved with that?
A plan! F A N T A S T I C 🌸
It’s your turn 🌈
How much prednisolone you take ?
farinaz fazaeli 20mg
So if you used donor sperm could you get pregnant? Not that you would but just curious
You’re so pleasant and beautiful. Your baby is going to be adorable. :)
😚😚😚😺😺suerte ánimo
why don't you just put the embryo in a surgate and have someone else carry it for you
Avery Hopkins because she doesn’t want that