How HIV kills so many CD4 T cells | Infectious diseases | NCLEX-RN | Khan Academy

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  • Опубліковано 25 чер 2015
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КОМЕНТАРІ • 180

  • @JillTheOddity
    @JillTheOddity 5 років тому +59

    This is the best explanation I've found regarding how HIV actually causes the loss of T cells. Thank you!

    • @ruzigold3606
      @ruzigold3606 3 роки тому

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    • @raesavage1892
      @raesavage1892 3 роки тому

      Have you tried watching the immunology wars video?

    • @scottseptne5239
      @scottseptne5239 Рік тому

      Why are you still living with HIV when *Dr Alued on UA-cam* have herbal remedy that cure HIV and other STD ? 🌹🌺💐

    • @jameswilliams3443
      @jameswilliams3443 Рік тому

      This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

  • @carlahead2945
    @carlahead2945 7 років тому +15

    I hope and pray that a cure for both AIDS and HIV can soon be found because there are so many people who are dying a horrible death. They suffer needlessly,you know? My heart goes out to people suffering with both HIV and AIDS.

    • @rivvermoune7770
      @rivvermoune7770 4 роки тому +2

      there are no cure for viruses...what you just have to do is to let your body mass produce those cells again...by consuming at least 20grams of ascorbic acid per day.

    • @Matthew-yc6nx
      @Matthew-yc6nx Рік тому

      ​@@rivvermoune7770Are you stupid?

    • @rivvermoune7770
      @rivvermoune7770 Рік тому

      @@Matthew-yc6nx you are the stupid...viruses are part of nature..and our immune system cells are part of nature too..let your immune system cells defeat those viruses and boost your immune systems cells

    • @Matthew-yc6nx
      @Matthew-yc6nx Рік тому

      @rivvermoune7770 Yes, viruses are part of nature. But telling people just to take ridiculously high doses of vitamin c to fight things like HIV is incredibly dangerous pseudo-scientific mal-advice.

    • @rivvermoune7770
      @rivvermoune7770 Рік тому

      @Matthew it is up to you if you want to follow what I suggested. high-dose of ascorbic acid and enough zinc and chromium and magnesium are good

  • @peytonwilliams1975
    @peytonwilliams1975 3 роки тому +17

    I work in a Computational Chemistry drug design lab, and my group simulates ligands with particular HIV proteins that aid in infection. This video and the previous one have been hugely helpful in my understanding of the life cycle of this virus. Thank you for your accessible and informative content.

    • @thomashelen856
      @thomashelen856 3 роки тому

      I’m completely cured from HIV virus 🦠 with the help of Dr.Auchi on UA-cam channel, I am finally free from HIV VIRUS..🙏🙏🙏

    • @danielioandima6020
      @danielioandima6020 3 роки тому +1

      Peyton Williams did you performed the HIV virus isolation in the blood stream /fresh drop blood from an infected person?

    • @thomashelen856
      @thomashelen856 3 роки тому

      @@danielioandima6020 HIV virus have cure and the best way to cure it is Herba medicine

    • @danielioandima6020
      @danielioandima6020 3 роки тому

      @@thomashelen856 wtf did saw the isolated HIV virus? of what it was cured?

    • @thomashelen856
      @thomashelen856 3 роки тому

      @@danielioandima6020 yes Dr.Auchi on UA-cam can help you cure your HIV virus 🦠

  • @markotomasevic8028
    @markotomasevic8028 4 роки тому +20

    It would be really cool if you also wrote some links for research papers in the info! :)

    • @scottseptne5239
      @scottseptne5239 Рік тому

      ❤ Why are you still living with HIV when *Dr Alued on UA-cam* have herbal remedy that cure HIV and other STD ? 🌹🌺💐

    • @jameswilliams3443
      @jameswilliams3443 Рік тому

      This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

  • @EMunozRN
    @EMunozRN 9 років тому +1

    Great explanation!!! Many thanks 😃

  • @rian.frealde
    @rian.frealde 5 років тому +1

    Wow... thank you for this video...
    Great job dude.

  • @peaceseeker9927
    @peaceseeker9927 3 роки тому

    Excellent insight. And the graphics were very well done.

  • @missfluffybuns7759
    @missfluffybuns7759 7 років тому +2

    mannnn.. thank you so much for this video

  • @tantralin735
    @tantralin735 8 років тому +1

    it is really helpful~~~get beeter understand for HIV~~Tks a lots~~

  • @mamiyah2934
    @mamiyah2934 4 роки тому +2

    Simplicity is your game thanks for downloading information on t-cells

  • @jacobwhite9791
    @jacobwhite9791 8 років тому +5

    This is so dope.

  • @imadakrame4463
    @imadakrame4463 3 роки тому +1

    Thanks a lot !

  • @snafu98104
    @snafu98104 7 років тому +6

    thank you very well put together and easy to understand for a laymen as myself

    • @snafu98104
      @snafu98104 7 років тому +1

      Sullivan Richard I have been HIV+since 87 thought the reason maybe I was taking tegretol which helps siezure disorders and bi polar and it supresess the white blood count in 87 my white blood count was low therefore low RNA particles also I was given shots in the army and Navy I am not a hematologist and I should of died along time ago how is it medically possible that I am alive today I take anti vitals today I want to give researchers my blood to study I knew for me this was going to be treated as a chronic illness thank God for rubbers cause I never would get laid I read the cure in Mexico something about positive molecules dropping an positive charge on HIV RNA and killing it can you explain hey I worked on helicopters now I know troubleshooting ch47's just can't figure out why I'm still breathing please answer this video is the bomb 😇😇😇🐺🐺🐺🐺

  • @LordM7md77
    @LordM7md77 8 років тому +1

    thank you

  • @ClemensLode
    @ClemensLode 3 роки тому +4

    Thank you for the video!
    Do you have examples against which type of diseases this chain reaction is/was evolutionary useful?

    • @scottseptne5239
      @scottseptne5239 Рік тому

      🎉🎉 Why are you still living with HIV when *Dr Alued on UA-cam* have herbal remedy that cure HIV and other STD ? 🌹🌺💐

  • @valtus
    @valtus 4 роки тому +1

    You're so insanely good at explaining stuff. Just fascinating watching your video.

    • @jameswilliams3443
      @jameswilliams3443 Рік тому

      This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

  • @bomhayhay
    @bomhayhay 7 років тому +1

    thanks

  • @1x1x1is1
    @1x1x1is1 5 років тому

    Thank you 🖖

  • @meredithgrey1297
    @meredithgrey1297 3 роки тому +1

    Thanks for existing 😭🦋❤️ loved this channel for the bottom of my hypothalamus ❣️

    • @jameswilliams3443
      @jameswilliams3443 Рік тому

      This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

  • @connorwilloughby2222
    @connorwilloughby2222 7 років тому

    Brilliant

  • @piyushchaturvedi632
    @piyushchaturvedi632 3 роки тому

    Thankyou ❤️🙏🏾

  • @senthilkumarpanneerselvam6657
    @senthilkumarpanneerselvam6657 7 років тому

    Awesome video

  • @IshantGupta5
    @IshantGupta5 8 років тому

    thank you for making it so easy!

    • @md.shanto8917
      @md.shanto8917 7 років тому

      Whо Elsе Wants Тo Cure Тheir Yeаst Infеeeеctiоn, Regаin Тhеir Naturаl Innеr Bаlancе aаnd Aсhieve LАSTING Freеdоm Frоm Caааndidа Rеlatеd Sуmрtоms?Clicссk Hеre -->twitter.com/cb89668e78b13a87f/status/784262969735516160 How HIV kills sо manу CD4 Т сееееlls

  • @odungaeunniey2258
    @odungaeunniey2258 Рік тому

    Very helpful. A big thank you

    • @jameswilliams3443
      @jameswilliams3443 Рік тому

      This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

  • @msfeezayousoff5290
    @msfeezayousoff5290 4 роки тому +1

    I wonder, how does it affect the cd8 t cells? or are they not affected at all?

  • @fraserwetende1729
    @fraserwetende1729 Рік тому

    really educative

    • @jameswilliams3443
      @jameswilliams3443 Рік тому

      This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

  • @rockoquels
    @rockoquels 4 роки тому

    #Mind Blown!!

  • @reneerenata6858
    @reneerenata6858 6 років тому +7

    Ur voice is nice n soft🙄. Good explanation tho👍

  • @bernardnathaniel
    @bernardnathaniel 3 роки тому

    can anyone explain what happen to the T cells that exposed to HIV but not being infected that then migrate to lymph nodes ? what will happen after that particular T cells enter the lymph nodes ?

  • @BrizAU
    @BrizAU 4 роки тому

    This may be a stupid question, but can NSAIDs or Corticosteroids help reduce cell death? Also, since HIV destroys CD4+ cells, can it be possible to somehow artificially stimulate cytokine production in the body to continue natural immune responses?

  • @pranavpieces
    @pranavpieces 6 років тому +1

    Does pyroptosis damage other T cells when not in lymph node?? For example like in blood stream??

    • @glitzyx4x852
      @glitzyx4x852 4 роки тому

      Pranav Venkatesh yes albeit not as often

  • @Frottagecub
    @Frottagecub 6 років тому

    As a Rh Negative blood type. Ebola and HIV doesn’t directly connect to blood types like A- . If they knew about Rh negative blood behavior - is it because the population is only 15% of possible elite controllers and it took 30 years to put two and two together finally? I have only intro to anatomy and physiology under my belt and can see the importance and possibilities. I am 41 and have lost loving, amazing human beings that could have been saved all this time if my blood and other Rh Negative blood types used for trials.
    I think there’s a huge underlining green to keeping things set back in this day and age.

  • @dawindersandhu4302
    @dawindersandhu4302 4 роки тому

    Abhi tak koi medicne nhi bani cd 4 cell ko incres krne ki . Onley art hai kya

  • @lanchanoinguyen2914
    @lanchanoinguyen2914 7 років тому +1

    and it would help the leukemia patient in the final stage.

  • @FeartheReaper54
    @FeartheReaper54 8 років тому +1

    I might've missed it, but how do cells behave with other retroviruses? Is pyroptosis a response from the common cold?

    • @glitzyx4x852
      @glitzyx4x852 4 роки тому

      FeartheReaper54 no the common cold viruses are harmless the immune system is trying to kick it out

  • @clo852able
    @clo852able 3 роки тому +1

    Love these videos but staying awake is hard with the practically whispering voices 😂

  • @andrewjichi3724
    @andrewjichi3724 3 роки тому +1

    i did not understand why they go to the lymph node, can someone help please

    • @thomashelen856
      @thomashelen856 3 роки тому

      I’m completely cured from HIV virus 🦠 with the help of Dr.okougo Herbalhome on UA-cam channel, I am finally free from HIV VIRUS..🙏🙏🙏

  • @KunalSingh-lz4jj
    @KunalSingh-lz4jj 3 роки тому

    Hello i am exposed with hiv pos girl 9 month ago. She was my wife sonhad sex multiple time but when she got pregnent we gone for test she tested pos and my hiv 4th generation test come out to be negetive. Since then i am testing every month my hiv test reports are negetive but my cd 4 count is very low now its 234. What to do ?Tried all type of test from PCR to western blot. All shoes negetive but when i go for cd4 count it is decreasing . The starting test shows me cd4 990 and presently it is 234. And i guess symptoms like fatigue is always there with me . Please help.

  • @corydross3367
    @corydross3367 7 років тому +1

    so lymph nodes are useless to hiv. I might have it. I believe but am not sure that I was exposed to hiv. 24 hours later my lymph nodes are pulsing for another 24 hours. I'm just scared now.

    • @ahansen9583
      @ahansen9583 6 років тому +1

      Komodo,
      Many types of infections can cause swollen lymphnodes, sometimes this is the result of an insignificant illness like a minor cold or allergy, and sometimes can be related to severe illness, this alone is not an indicator of HIV infection.
      Unlike risk groups of HIV infection in Africa that is purported to cause AIDS in men, women, and children equally (a reflection of government grants for HIV driven associations vying to substantiate receiving federal monies)..In the USA and Europe AIDS is biased, affecting and killing mainly men with substantial drug addictions, regardless of HIV seropositivity. Hemophiliacs are prone to developing AIDS related to the number of Factor 8 blood transfusions they endure, irrespective of wether or not they have an actual HIV infection.
      So, if you live in one of these countries, unless you meet the criteria above...it’s unlikely that you’ll ever develop AIDS, even if you were HIV positive and had no treatment.
      In addition, HIV is grown by labs in immortal T Cell lines without causing a single T Cell to die, HIV is not very toxic to T cells as indicated by the video...it infects very few T Cells and is not directly responsible for the majority of cell death. As long as any enviornmental toxic exposures are limited, the human body can replace lost T cells faster than HIV could potentially kill them, which is why HIV does not ever result in AIDS in healthy people.
      An online readable copy of a published book describing the symptoms, history, infection, risk groups, therapy, and co-founders of HIV/AIDS and the extent of the medical literature with medical citations and can be read for free here: www.whale.to/c/Inventing-the-AIDS-Virus%20(1).pdf

    • @elhombredeoro955
      @elhombredeoro955 5 років тому +1

      Get a test buddy. Though HIV is a serious infection, it's not as nightmarish as people make it to be.

  • @francescoranchi7415
    @francescoranchi7415 4 роки тому

    Hello, very clear explanation but what I'm having trouble understanding is how does the not infected cell fail. U said that it isn't infected, but right after u said that protein ifi16 detects rna transcription and activates caspase 1 which then creates interleukin b1 etc...
    But when RNA transctiption starts, isn't the cell infected? or can the transcription take place without the cell being infected.
    So when does the cell become infected?

    • @msfeezayousoff5290
      @msfeezayousoff5290 4 роки тому

      Hi, I understand your confusion. I think the uninfected cd4 cell death occur in the lymph nodes, when one of it's cd4 secretes IL b1 and undergoes pyroptosis, triggering chain reaction to the bystander cd4 cells. I think that's what he meant by uninfected cd4 t cells death.

  • @jameswilliams3443
    @jameswilliams3443 Рік тому +1

    This has been a challenging time, and I appreciate you so much Dr Alued, you have created a life that I thought was lost, thank you so much for curing my sister from genital HIV I am grateful

    • @UfunuoSt
      @UfunuoSt Рік тому

      Dear James, please I need your help, how did she get out of that? Help me please, I am loose a life too.

  • @amazonfire8145
    @amazonfire8145 2 роки тому

    The ones that need to go into self destruct the most are the resovoir ones. Why don't they?

  • @charted8015
    @charted8015 2 роки тому

    The real question is even if pyroptosis does bot happen, do cd4 cells still get killed by hiv eventually? If so, the pyroptosis is not the real problem. The real problem is still how to eradicate the virus in the body.

  • @joshuarandall6041
    @joshuarandall6041 6 років тому

    Wow.

  • @Me-the-One-G
    @Me-the-One-G 4 роки тому

    I ve read that sebhorreic dermatitis it s relatit whit hiv but i think that it coul be related to other desease, as like as angular cheilites, beside so many hiv negative tests after so long perioud. All hiv symtoms i think could be from another desease....similar maybe...a herpesvirus...somth

    • @sandrodream5418
      @sandrodream5418 3 роки тому +1

      yes but you have to make more analysis after a while

    • @Me-the-One-G
      @Me-the-One-G 3 роки тому

      @@sandrodream5418 i retest hiv ag 1 ab 1 M Oand Hiv 2 ab...after 2 year and all negative..a wb test for Hiv 1 negative...but i have always all syntomps...i ve tested all other desease and negative....i have arthritys...dyarheea ..rashes etc....it ruin my life...from over 1 year ago i ve testet 3 cd 4 cd8 counting....the first has over limit cd8 and cd4 was 1170....than the second test get cd 8 in regular limits but cd 8 961and 2 days ago again cd 8 over limit at 1150 and cd 8 1250....cd 4 percent was 44 % , 46% and 44% again...pls give ame an advice....thanks

    • @Me-the-One-G
      @Me-the-One-G 3 роки тому

      It can be some strain or group undetectable by 4 th gen tests?!....i ve made it 10 times in different clinics...

    • @Me-the-One-G
      @Me-the-One-G 3 роки тому

      At the very first time 2 years ago....beside other symptoms i ve loss 7 kg weigh....

    • @sandrodream5418
      @sandrodream5418 3 роки тому +1

      @@Me-the-One-G if you wanna be 100% sure you have to make ELISA 4th generation test but I think you are OK, dont worry dude

  • @parecheg
    @parecheg 8 років тому +10

    The big bang is easier to understand

  • @clydecash5659
    @clydecash5659 Рік тому +1

    Antivaxxers say this is fake

  • @giselleshrestha6871
    @giselleshrestha6871 2 роки тому +1

    Thank you #Drkanayo
    Peterson on UA-cam for being the reason why am smiling today after so many failures,
    your 14 days herbal supplement for hiv is indeed an active one. Keep saving lives sir.