Pathogenesis of Neuropsychiatric (CNS) Systematic Lupus Erythematosus- Prof Graham Hughes

The neuropsychiatric systemic lupus erythematosus (NPSLE) is the least understood, yet perhaps the most prevalent manifestation of lupus. The pathogenesis of NPSLE is multifactorial and involves various inflammatory cytokines, autoantibodies, and immune complexes resulting in vasculopathic, cytotoxic, and autoantibody-mediated neuronal injury.
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