Cre-Lox, Optogenetics, and the Brain Reward System

[@johnkim8070]

Amazing video. So well explained!

[@adamschwarz7186]

guys u are the best !! I would love to see more videos summarizes cool papers and methods from neuroscience !!

[@senorsuraj8428]

This video bouta save my Midterm grades. Bless up!

[@sristyhalder6551]

Thank you so much.... Cant appreciate enough... Keep it up....

[@dannyholley]

Excellent video. Well done, you! :-)

[@MateusSilva-qs3wx]

Well done! Thank you for the video.

[@JosieYapsALot]

Came for the neuroscience, stayed for the evil laugh 😈

[@melhel21]

Isn't halorhodopsin an ion pump and not a channel??

[@hcantu8705]

Well done!

[@kirstiebelanger7757]

This video was great, thank you so much!

[@marinab2177]

This video has been very helpfull to me! Thanks a lot

[@jy4205]

save my day, thanks!

[@kierandesmond6479]

awesome

[@ireneoirapta7011]

Now you know what the covid vaccines are for.

[@1Sinep1]

Hi neural academy, quick question, wouldn't it be an option to inject the AAV virus carring a TH specific promotor with the Channel rhodopsin gene in the VTA, instead of using the CRE recombinase mechanism trough a transgenic mouse model?
Great video btw

[@MicTott]

Hey Evert, you may have found this answer already, but incase you didn't or anyone is also curious: AAVs have a limited carrying capacity and a cell-type specific promotor simply takes up too much space. So, for now scientists are stuck using Cre-driver lines with AAVs, but other viral vectors are being worked on, such a lentiviruses, which have much greater carrying capacity.

[@1Sinep1]

@@MicTott interesting, thanks

[@DiegoErnesto7]

Thank you for the video! Very useful! :)

[@Ben-ok2ue]

Super helpful thank you

[@ihorabsent1280]

Amazing video, thank you very much for telling this information)
I'm inspired) *guy who has opened optogetics for himself recently*)))

[@addoul99]

MWAHAHAHAHAHA