Can We Cure Aging?: Unpacking the Interventions | Andrew Steele, PhD | The Proof Podcast EP

Поділитися
Вставка
  • Опубліковано 23 лис 2024

КОМЕНТАРІ • 59

  • @DrAndrewSteele
    @DrAndrewSteele Рік тому +20

    Thanks for having me on the show! :)

    • @bonniek7228
      @bonniek7228 Рік тому +4

      It’s depressing listening to these young people talking about 60 year olds like we’re dinosaurs! I don’t know how I got this old so fast - but I’m looking for some hope and guidance to stay healthy as long as possible. Not sure I found much in this interview. But there’s hope for my kids- so that’s good!

    • @DrAndrewSteele
      @DrAndrewSteele Рік тому +6

      ​@@bonniek7228 I don’t think 60-somethings are dinosaurs! :) Very sorry if anything came across that way, and I really think it would be great if there were some more older voices discussing ageing-we didn’t get onto this in our chat, but the exclusion of older people from both advocacy and research is something I talk about in my book. It’s frustrating that many or most users of eg cancer medicines might be older adults, but the drug trials are often done in young, otherwise healthy people to make it more likely to get a positive result… And please do call me out if I do unintentionally say anything dinosaur-accusation-adjacent. :)

  • @greensmoothieparty
    @greensmoothieparty Рік тому +26

    My elderly mom had a follow up appointment with her physician last week.
    According to the Levine Biological Age Calculator based on her latest bloodwork test results, she has now aged minus 18 years during the last 4 years. She eats a Slow Carb, Slow Fat diet style - whole plant food carbs and whole plant food fats both with fiber, helping the body fully assimilate the nutrients without overwhelming its metabolic systems and pathways.
    Here is her menu for a typical day:
    Breakfast: Organic steel cut oats with some buckwheat and wild blueberries, raspberries, 1/2 banana, tablespoon of ground flax and ground chia seeds, tablespoon of hemp seeds, organic soy milk, Ceylon cinnamon.
    Lunch: Green smoothie heavy on the low-oxalate greens (frozen kale or collard greens, frozen pineapple, banana, orange, lemon wedge with rind, organic soy milk, avocado sliver, amla powder, dulse flakes, apple cider vinegar, blackstrap molasses, nutritional yeast, small scoop of hemp protein powder, fresh ginger, medjool date, fresh kale, cold-pressed flax oil) with a small handful of almonds and walnuts - or - some soup and salad.
    Before dinner snack: one apple.
    Dinner: Variety of simple meals including spaghetti, chili, vegetable soup with beans, lintel miso soup with organic tofu cubes/onions/mushrooms/kale, split pea soup with onions/mushrooms/carrots/celery/potato, roasted vegetables (squash/carrots/potatoes), rice and beans bowl with onions/mushrooms/kale/peppers/salsa, organic tofu scramble with onions/mushrooms/peppers/kale/turmeric/nutritional yeast, broccoli, asparagus, green beans, etc.
    Dessert: frozen banana whip with papaya or strawberries topped some days with a couple of macadamia nuts or a Brazil nut - or - some red grapes.
    Make sure to include G-Bombs every day for optimal immune system (i.e. - greens, beans, onions, mushrooms, berries, seeds).
    Avoid most processed foods. Include tofu perhaps twice a week but not more. Stop eating after an early dinner except for a few pistachios before bedtime.
    Cheers!

    • @plants_and_wellness1574
      @plants_and_wellness1574 Рік тому +2

      Wow, thank you so much for sharing this 🙏💕

    • @southerngirl1408
      @southerngirl1408 Рік тому +1

      Thank you for all that helpful information! It’s wonderful that she’s aging backwards and eating such a healthy diet. What is the real age of your Mom?

    • @greensmoothieparty
      @greensmoothieparty Рік тому +2

      @@southerngirl1408 84 1/2 but please don't tell anyone 😮

    • @southerngirl1408
      @southerngirl1408 Рік тому +1

      @@greensmoothieparty She’s Amazing! I promise not to tell anyone her age, Lol 😂

    • @TheOakenwulf
      @TheOakenwulf Рік тому

      Whoa! That's almost exactly how I make oatmeal.

  • @carinaekstrom1
    @carinaekstrom1 Рік тому +12

    Getting older without deteriorating. I'm holding out hope.

    • @jmc8076
      @jmc8076 Рік тому +2

      Same. For me Dr Ellesworth Wareham was/is my inspiration. He lived very long but also very well. Retired from heart surgery at 95.

  • @StephenMarkTurner
    @StephenMarkTurner Рік тому +4

    When I was younger, there was the anti aging info from Durk Pearson and Sandy Shaw on tv talk shows. They are still with us, so I guess they did a pretty good job with the science at that time.

  • @susymay7831
    @susymay7831 Рік тому +1

    Please keep up with the fabulous timestamps!! ❤❤❤❤❤

  • @SirTenenbaum
    @SirTenenbaum Рік тому +7

    This was an excellent interview. I also found Andrew Steele's book "Ageless" to be very informative on the scientific research targeting the biology of aging.

    • @DrAndrewSteele
      @DrAndrewSteele Рік тому +1

      Thank you! Really glad you enjoyed Ageless, and it was a pleasure to chat to Simon!

  • @EugeniaSergeeva
    @EugeniaSergeeva Рік тому +7

    the ideal speaker... does exist)) no need to change speed settings😁

    • @DrAndrewSteele
      @DrAndrewSteele Рік тому +3

      Hahaha yeah sometimes I have to recommend people use the 0.75× speed control…

    • @EugeniaSergeeva
      @EugeniaSergeeva Рік тому +1

      @@DrAndrewSteele 👍😅

  • @jaynepower4330
    @jaynepower4330 Рік тому

    Brilliant interview like all the others I’ve seen on your channel, THANKS!
    Notice a lot of folks with questions about high blood pressure. Have you covered hibiscus tea?
    I’m 72 in recovery from major operations with massive muscle loss…a newbie to the science of protein, now getting stronger.
    But couldn’t get my BP down with exercise.
    Still very limited movement but perfect pressure now thanks to daily yoga breathing & the tea. My doctors are amazed at the improvement. 170/95 to consistent readings around 130-35/70-80.
    I’m learning so much, finally making progress thanks to people like you & your wonderful guests. 🙏

  • @Jaelri
    @Jaelri Рік тому +2

    Such a clear communicator. Really interesting stuff.

  • @k.h.6991
    @k.h.6991 Рік тому +3

    My guess would be that climate change and other environmental issues are going to negatively influence life expectancy as well as health span.

  • @creativesource3514
    @creativesource3514 Рік тому +2

    Can you make a chart please presenting what Steele, Attia, Bryon Johnson , David Sinclair and Aubrey deGrey think? What do they all agree on and what do they each emphasise?
    I am confused with all the information in this field. They all claim to be evidence based.

  • @k.h.6991
    @k.h.6991 Рік тому +1

    about meditation: it just doesn't work for everybody. So the starting point with that kind of intervention should be: does it work for you? Complicated by the fact that for some people the positive effect of meditation can be felt right away. For others it takes ages for it to 'stick'. And probably there are people for whom it doesn't work at all - though teasing that out is tough as well.

  • @kst157
    @kst157 Рік тому +2

    Excellent interview - very detailed, ahead on new technologies and the future, and wide ranging questions & balanced answers - thank you Andrew and Simon.

  • @SMT_2024
    @SMT_2024 Рік тому

    Some people are in a permanent race for fitting in or for gaining or for building a family which always is based on lying in order to show up as a “model” for others, that kind of person who trusts medical care and ends up in hospitals to solve problems which are only a consequence of their actions, there are a few along side those people living side by side but not together who are different and determined to participate at collective consciousness through personal growth, those people are very careful with themselves and the others if necessary, very aware and quite sensitive if it comes to noticing their own body, because we definitely are biological beings and our bodies sends us signals before the beginning of an illness, but only a few are aware of this simple fact… veganism and sports improves the level of awareness! Genes are important but this is not a life sentence, anything can be improved! Thank you Simon for great talks!😊

  • @tosca...
    @tosca... 10 місяців тому

    Such an interresting interview. I feel as though things I haven't thought about at 72 has exploded in my WFPB brain. There was so much fast talking that 1. Will have to listen again, and 2. Will have to buy the book. I will read it very fast! 😂

  • @arleenm7367
    @arleenm7367 Рік тому +3

    Thanks again for another interesting discussion. I'm wondering if there a website or resource where people can go to sign up to take part of one of these nutrition studies?

  • @carinaekstrom1
    @carinaekstrom1 Рік тому +1

    Thank you, very encouraging.

  • @b.p.6246
    @b.p.6246 Рік тому +1

    What if we got rid of half the chemicals in the environment and provided healthier food instead of always looking at bandaids?

  • @musicmonsterman8395
    @musicmonsterman8395 Рік тому +1

    Hey Simon I am pretty confused with the concept of dietary cholesterol. You have people in the plant based movement like Dr. Greger who say any amount of cholesterol whatsoever is unhealthy and dangerous. And then you have guys like Dr. Attia and Dr. Hyman (both of whom I respect) saying dietary cholesterol doesn't effect serum levels, so it is safe to eat eggs, chicken and lean meats etc as long as saturated fat is kept in check. Wondering if you could address this or make a quick video on the topic.

    • @musicmonsterman8395
      @musicmonsterman8395 Рік тому +1

      By the way, for what it's worth, I think a GREAT video would be a careful and unbiased list of the healthiest and unhealthiest animal foods based on the current research so folks have an idea of what to aim for if they should decide to eat such foods.

    • @musicmonsterman8395
      @musicmonsterman8395 Рік тому +1

      @@TheProofWithSimonHill Yeah, I need to watch that interview you did with Thomas but that makes sense to me so thank you! I asked Gil the same question and he gave me a similar response.

  • @StephenMarkTurner
    @StephenMarkTurner Рік тому +1

    Joel Fuhrman would probably say that calorie restriction should be very small, perhaps 50 Calories per day, and nutrient density should be very high as you are only trying to restrict the fat and carbohydrate, not fibre and nutrients.

    • @StephenMarkTurner
      @StephenMarkTurner Рік тому +1

      @@TheProofWithSimonHill That is wonderful. I think you will enjoy that conversation. This current guest sounded a bit like Joel when he talked about protein 'quality'.

    • @creativesource3514
      @creativesource3514 Рік тому

      What do you mean calorie restriction of 50 cal / day? You mean a caloric deficit of 50 cal/ day?

    • @johnsmith-zf1fd
      @johnsmith-zf1fd Рік тому +2

      @@TheProofWithSimonHill Amazing, waited a long time for a Fuhrman interview on this show!

  • @peterz53
    @peterz53 Рік тому +1

    thanks. Good discussion. On the metformin study, the definition of non diabetic likely includes HbA1c of < 5.7%, which includes a lot of people who are not optimum in terms of biometrics. Would be interesting to parse the results against people who have HbA1c around 5% or a bit less, confirmed to also have very low insulin. Seems too easy to jump to the conclusion, which Andrew does not do, that metformin is a good adjunct for people with optimum biomarkers, as opposed to acceptable biomarkers.

    • @carinaekstrom1
      @carinaekstrom1 Рік тому +1

      I agree about Metformin. I wouldn't take for granted that the lowest HbA1c is necessarily what reflects the best health, though.

    • @DrAndrewSteele
      @DrAndrewSteele Рік тому +2

      Glad you enjoyed it! Yes, there are loads of caveats with the observational stuff on metformin… I just wish someone would stump up the last few million so TAME could do the proper randomised version and we could stop trying to read tea leaves!

  • @angelahorsburgh9954
    @angelahorsburgh9954 Рік тому +1

    Great interview! Thank you. Andrew Steele is super amusing as well as informative. Am struggling to convince my husband to cut off his testicles so he can live as long as me 😂

  • @donatina1987
    @donatina1987 Рік тому +3

    One of the best episodes!
    Is there a way to not get white hair? 😂😂 I found two the other day … 😅

    • @MindVersusMisery
      @MindVersusMisery Рік тому

      I'm not sure about grey/white hair. That may have more to do with genetics than lifestyle, but I don't know. I'm personally awaiting Dr Michael Gregers book How Not To Age, which is released in december, to learn more about anti-aging. And some of my motive for wanting to learn this is vanity. I want to look good for longer. 😉

  • @squamish4244
    @squamish4244 21 день тому

    I think the only way we're going to crack this problem for people alive today with very powerful AI that can make sense of the 5,000 medical papers published _every day_ to sort out the best interventions, plus all the new technologies being implemented in drug discovery or will be over the next decade or so. There's just no way otherwise, it will take a century to do this.

  • @janetbrowning6602
    @janetbrowning6602 Рік тому

    Longevity is decreasing in the western industrial counties, not increasing.

  • @alexmason420
    @alexmason420 Рік тому

    Imagine to live till 2150

  • @sethboviper
    @sethboviper Рік тому +1

    The conflict of interest issue is what bothered me about the interview with Matt. The whole interview he presented as a scientist who seemed to have found some interesting findings, but when it came out at the end that he was starting to go into business based on these findings red flags were raised. The soy guy saying glyphosate is safe lessened my trust in him as well.

    • @sethboviper
      @sethboviper Рік тому

      @@TheProofWithSimonHill yes and no. Andrew made a comment about conflict of interest in nutritional research about half way through the convo, which reminded me of the 2 previous guests of yours that i thought were slightly sketchy in that regard. for instance, wrt soy I think the consensus is it's good and I eat tofu and especially tempeh, but I sure as heck eat organic soy to avoid/minimize herbicide exposure.

  • @iwnunn7999
    @iwnunn7999 11 місяців тому

    Why's he speed talking??

  • @TheProofWithSimonHill
    @TheProofWithSimonHill  11 місяців тому

    Hello Friends,
    I'm curious to know which part of the conversation you found the most insightful and engaging. Also, if you have any other questions related to this subject, please post them below this comment. I'll make sure to include them in our next discussion.