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Endoplasmic reticulum and Golgi bodies | Biology | Khan Academy

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  • Опубліковано 6 січ 2014
  • Structure of the endoplasmic reticulum and Golgi body (Golgi apparatus), and how they function in secretion of proteins from the cell.
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КОМЕНТАРІ • 190

  • @KainusGulch
    @KainusGulch 10 років тому +251

    Has any one told Khan he has a good voice for this stuff. Thanks for the vid.

  • @shivathanu1
    @shivathanu1 5 років тому +411

    endoplasmic reticulum sounds more like a harry potter spell than anything

  • @asimgodil8008
    @asimgodil8008 6 років тому +46

    The thing I like about Sal is his thoroughness. He really truly explains everything and that is why his videos are great.

  • @CRockstroem
    @CRockstroem 10 років тому +43

    Are you intentionally making these videos right in time for my exam next week? Gotta love what you do!

  • @jjjkeel1260
    @jjjkeel1260 10 років тому +51

    Laughed with that thing you said about the endoplasmic reticulum sounding good as a band name! Haha your videos are the best. in time for my exam in a few days, thank you so much!

  • @cardogkitchen4106
    @cardogkitchen4106 8 років тому +106

    I will name my next dog Endoplasmic Reticulum just because it sounds cool.

  • @amansaxena7872
    @amansaxena7872 8 років тому +132

    4 minutes and 30 seconds into the video:
    ''This is what we are going to focus on in this video"

    • @sexydds2010
      @sexydds2010 7 років тому +4

      Thanks for the heads up

    • @acalp
      @acalp 6 років тому +16

      The beauty of these videos is the background introduction. One need to learn that for better presentation.

    • @oliviaok625
      @oliviaok625 4 роки тому +1

      I personally feel like the introduction is really important because it's a review of the topics already learned that lead up to this concept. It shows how they all fit together in a sequence :)

  • @leesj6327
    @leesj6327 9 років тому +13

    'perhaps an even better name for a band' haha cutest thing I've ever heard ;)

  • @jomppe1428
    @jomppe1428 7 років тому +5

    These videos you upload veritably help to understand the bigger picture of a certain event in a cell. Making it possible to dig deeper into transporters etc. in med school. Thanks!

  • @TheHarabeli100
    @TheHarabeli100 8 років тому +84

    Thank you! I understand you much better than my books that are in my native language.

  • @jaquelinebello5219
    @jaquelinebello5219 6 років тому +3

    You are just the best. Your voice is strong, you explain everything so plausible ( and english is not my first language ) and I love!!! how you repeat things while you write them out. This way I don't even have time to get
    distracted. Its such a great way of teaching. Thank you so much!

  • @80601136
    @80601136 10 років тому +106

    wow I never knew that cytoplasm is everything in the cell ;___;

  • @210monther
    @210monther 9 років тому +9

    شكرا جزيلا

  • @rmcelhatton151
    @rmcelhatton151 8 років тому +28

    Was hoping for something a little more complicated Didn't add anything to my knowledge. Need more detail i.e COPI and II vesicles and vesicular tubular clusters or more about the Golgi-E.R retrieval pathway were soluble proteins require a receptor for their 4-amino acid recognition sequence (KDEL).

    • @lanapshtiwan2117
      @lanapshtiwan2117 5 років тому

      This is more of an high school video, and it is in the SAT Bio Test playlist like you see, so I don't think it should be that advanced to get into such details.

  • @sqrt-1646
    @sqrt-1646 4 роки тому +5

    4:14 The relevant part in accordance to the title.

  • @kionimarshall8920
    @kionimarshall8920 5 років тому +1

    This was so clear, before I watched this I was so confused what a Lumen was, and the internet did NOT help. THANK YOU!

  • @sciencenerd7639
    @sciencenerd7639 2 роки тому +2

    I'm happy that he clearly explained the fact that the nuclear envelope consists of two separate membranes (for a total of four leaflets). Great job!

  • @hopnotbellatrix290
    @hopnotbellatrix290 10 років тому +9

    Mr. Khan., thanks for yet another great illustrative video.

  • @mccplayzmc7113
    @mccplayzmc7113 4 роки тому +8

    after watching this video twice, i now possess great intellectual capacities. i can cause natural disasters by sneezing.

  • @user-gr9fh2tb8g
    @user-gr9fh2tb8g 3 роки тому +1

    Really kind description about Golgi apparatus. Thank you for this video.

  • @sciencenerd7639
    @sciencenerd7639 2 роки тому +1

    The mRNA does not find a ribosome associated with the endoplasmic reticulum. Translation always begins in the cytosol, then when the ribosome gets to the signal sequence of the mRNA, then the ribosome and mRNA attach to the endoplasmic reticulum and translation proceeds there.

  • @saherreda9454
    @saherreda9454 8 років тому +2

    khan this video is awesome keep it up but i just have a little note which is when you drew the ribosome you drew a circle but you didnot clarify that ribosomes donot have any membrane so people would misunderstand thank you for your work!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

  • @zakirhossain9554
    @zakirhossain9554 6 років тому +1

    east and west khan academy is the best

  • @MoizAsimagar
    @MoizAsimagar 7 років тому

    Man i could swallow all the lectures given by him ! Now i love Biology !

  • @demotorjohnrobieh.9322
    @demotorjohnrobieh.9322 3 роки тому +1

    I love how you explain this lesson. This helped me understand the process😄

  • @extremelyhappysimmer
    @extremelyhappysimmer 5 років тому +3

    so it's effectively a quadruple lipid layer?

  • @mechikaboombayah4960
    @mechikaboombayah4960 5 років тому +3

    Now that I think of it ENDOPLASMIC RETICULUM is actually a really good name for a Band😂😂👍👍

  • @yettibunny6906
    @yettibunny6906 2 роки тому +1

    you sound like Kronk from Emperor's New Groove and it helped me get this so thanks lol

  • @mynameissumzpower4793
    @mynameissumzpower4793 7 років тому

    thanks so much! Watched it 2 times, I understand it now.
    Keep doing what you're doing, really helpful. I have a confusing teacher.

  • @kianadiykia4914
    @kianadiykia4914 Рік тому +1

    Thank you so much.

  • @zsofiaszabo5383
    @zsofiaszabo5383 4 роки тому

    Very hood video, thank you! Finally I understood how ER work, and why.

  • @Be1smaht
    @Be1smaht 6 років тому +4

    So simple yet so complicated

  • @chuggaroo
    @chuggaroo 5 років тому +1

    Domo Arigatogozaimashita Sal Khan! Watashi wa anata ga shite iru koto ni totemo kansha shite imasu! Watashi wa anata no oshie no naka kara nihongo o manabimashita!

  • @itsReallyLou
    @itsReallyLou 2 роки тому

    You are doing a great job. Please take the following as a very minor suggestion: I, for one, would appreciate les re-iteration in the dialog. This may only be me, so please take with a grain of salt.

  • @anouarbou1829
    @anouarbou1829 2 роки тому

    You're such a bless to humanity !

  • @kin4seikatsu844
    @kin4seikatsu844 7 років тому

    Why are you not teaching my class!!! This makes so much more sense then how my professor explained it... Thanks you!!!!!

  • @MysticMD
    @MysticMD 10 років тому +3

    Thank you so much! Always informative and accurate!

  • @tyronebigsby2169
    @tyronebigsby2169 Рік тому

    Extremely clear and concise thank you!!!!!!

  • @nirbhaysingh4232
    @nirbhaysingh4232 3 роки тому

    students can understand 100 percent concept, by watching your video

  • @zoyeb100
    @zoyeb100 6 років тому +1

    Wow.....I used to think cytosol and cytoplasm are the same thing.

  • @malolansriram6328
    @malolansriram6328 4 роки тому +1

    Sal...you Rock 🔥🔥🔥🔥🔥

  • @aryakeykhosravi4345
    @aryakeykhosravi4345 2 роки тому

    thank you brother that was useful

  • @rashminijhawan3151
    @rashminijhawan3151 7 років тому

    finally understood why some proteins are translated in cytoplasm and some in ER! :D

  • @subhajitganguly6291
    @subhajitganguly6291 4 роки тому +2

    7:01 in this time ur laughing 🤣

  • @johntindell9591
    @johntindell9591 4 роки тому +1

    thank you

  • @marinpz1827
    @marinpz1827 5 років тому +3

    When you put it on x2 it sounds like he repeats the phrase 10 times. Or x0.25.

  • @MYfriendsknow
    @MYfriendsknow Рік тому

    THANK YOU & PEACE

  • @sahidurrahaman314
    @sahidurrahaman314 4 роки тому +1

    The sir like a week and like after disease 😒😑 but enthusiastic

  • @kashafseducationalsite363
    @kashafseducationalsite363 6 років тому

    Ur lecture make this topic so easy

  • @laylaa.hassanbiology1264
    @laylaa.hassanbiology1264 Рік тому

    thank you very much.
    is there any benefit from connection between perinuclear space and lumen of endoplasmic reticulum?

  • @bubbybear6215
    @bubbybear6215 4 роки тому

    Does anyone know if I’m just starting on these cellular things which khan academy vid shd i start from to get the fundamental idea

  • @ximelp7268
    @ximelp7268 6 років тому +1

    Ximena Leyva Peralta
    Do the Rough E.R. and the smooth E.R. look different from each other?

    • @josephdahdouh2725
      @josephdahdouh2725 5 років тому +1

      Yes Smooth has no Ribosomes while rough do have them(like circular dots on them).

  • @leesiuki
    @leesiuki 7 років тому

    really useful for my studies. Thank you !

  • @sahidurrahaman314
    @sahidurrahaman314 4 роки тому

    When I read in class 5 to 10 .I have to read to provide money but now I am 11 and I learn many things without money

  • @JessicaAMercado
    @JessicaAMercado 7 років тому

    i can't believe i found the videos my high school teacher showed us. He wouldn't even teach, just show this freaking videos

  • @nerinkyazimova2119
    @nerinkyazimova2119 4 роки тому

    It is wrong to say that the protein is synthesized in the ER. It should be made clear that only specific ones are going there, the ones which have specifiek signal sequence for it. Some protein are synthesized in the
    cytosol.

    • @nerinkyazimova2119
      @nerinkyazimova2119 4 роки тому

      Proteins wich have specifiek signal sequence are synthesized in ER.

  • @vladusa
    @vladusa 3 роки тому +1

    This is beautiful. Thank you Khan!

  • @samiakhan6659
    @samiakhan6659 5 років тому

    All on a sudden biology had become fearful and boringstuff for me.Thnx for making me enjoy it again.

  • @alrayyaniQtr
    @alrayyaniQtr 8 років тому +4

    The nucleus is surrounded by a double nuclear membrane and each membrane is a bilayer. Well is it the same as a phospholipid bilayer?

  • @tranghyunnie2483
    @tranghyunnie2483 10 років тому

    very good for me! tks u so much

  • @user-ik6hl9wu5t
    @user-ik6hl9wu5t 5 місяців тому

    Is it a bilipid layer or lipid bilayer? If bilipid, what are the two lipids? "Bilipid layer" yields nothing in a search.

  • @user-wf6qs8um8f
    @user-wf6qs8um8f 2 роки тому

    nice veido, and detialed explanation. But dont be nervous, you can do better!

  • @janwaynerayverrasco1571
    @janwaynerayverrasco1571 Рік тому +1

    I think there's a story behind why you are laughing when mentioning ER as band name🤣

  • @medukameguca5071
    @medukameguca5071 2 роки тому

    We've been told to give a presentation on this and I honestly don't know how I would go about presenting without knowing the stuff going on.
    Tldr: Idk anything and I'd be in a pickle without Khan Academy 😂

  • @aena_
    @aena_ 3 роки тому

    Great sir thanks

  • @xoxomangakcorxoxo
    @xoxomangakcorxoxo 7 років тому

    What happens to the protein inside of the ER? Does it just get wrapped up and sends it to places? And where else does he proteins move inside the cell? (Besides the golgi body)

  • @parinozakrami9768
    @parinozakrami9768 6 років тому

    The best you are, Khan academy.

  • @Alesha07
    @Alesha07 8 років тому

    Thank you! This video really helped.

  • @mariamanescu7809
    @mariamanescu7809 2 роки тому

    Thank you !😍

  • @kazebeck5016
    @kazebeck5016 5 років тому

    better than my lecturer :) thanks for the video. (y)

  • @butyoudidnt4387
    @butyoudidnt4387 2 роки тому

    You are a grade-saver, sir

  • @deepikasaxena01
    @deepikasaxena01 4 роки тому

    My Kids can learn from you

  • @sakura5948
    @sakura5948 2 роки тому

    Hmm did u missed the point that the protein that join the golgi body carbohydrate is added to form glycoprotein ?

  • @rijabakhtawar8197
    @rijabakhtawar8197 7 років тому

    Correct me if I am wrong, but I think that PROTOplasm is everything inside the cell, which Sal confuses here for CYTOplasm, which is the gel like fluid around the organelles.

    • @tofireworks
      @tofireworks 6 років тому

      Cytoplasm= includes everything in the cell except the nucleus. Cytosol= soluble part of cytoplasm (gel-like fluid)

  • @ahmadawaiz6833
    @ahmadawaiz6833 4 роки тому

    Sir khAn your voice is awesome👌👌👌👌👌

  • @kt22ski
    @kt22ski 4 роки тому +1

    Anyone else regretting signing up for the SAT subject test after having not taken for biology for three years? meeeeeeeee

    • @Jewelbrean
      @Jewelbrean 4 роки тому

      Rachel Delaney I’m with you too 💁🏾‍♀️ We got this

  • @ayeshamansoor991
    @ayeshamansoor991 4 роки тому

    everthing was explained amazingly but i got a question .....what is cytogel?

    • @rudra8293
      @rudra8293 4 роки тому

      If you want to know what Cytogel is, its a company. But I'm pretty sure it's Cytosol but he might have said cytogel in the video. Cytosol is, in short, a water based solution that contains ions, small molecules, and macro molecules. It is a place where a lot of metabolic reactions take place.

    • @ayeshamansoor991
      @ayeshamansoor991 4 роки тому

      @@rudra8293 thanks i had studied about cytogel that its a part of cytoplasm and so is cytosol and i was told that cytgel is the near the nucleus part the one with lots of thickness

  • @isajadbhat
    @isajadbhat 8 років тому

    THIS IS GREAT!

  • @clashingkingamv4315
    @clashingkingamv4315 6 років тому

    Omg golgi hma matag very nice explanation

  • @amnakhushi4571
    @amnakhushi4571 6 років тому

    Actually..i have a confusion ..golgi is also formed from the budding of SER and also modify the proteins coming from ER..?

  • @johntindell9591
    @johntindell9591 6 років тому

    Thank you, so helpful

  • @lauelibre
    @lauelibre 7 років тому +13

    watch on 1.25x

  • @bradsavard8339
    @bradsavard8339 10 років тому

    These vids are great!

  • @Bot12-w9u
    @Bot12-w9u 4 роки тому

    I wish i would be compatible to your pronounciation

  • @jesselee.
    @jesselee. 6 років тому

    wowsers this is awesome

  • @nickolausafon5458
    @nickolausafon5458 4 роки тому

    Insaene in the Memebraene!!

  • @shannonmcclain2036
    @shannonmcclain2036 5 років тому

    Yes! Yes! Yes!

  • @originallassics2859
    @originallassics2859 3 роки тому

    Nucleus doesn't have double membrane it's one membrane with two parts

  • @arrianah5080
    @arrianah5080 3 роки тому

    so after the mRNA spits out the protein into the ribosome, it still goes out to the cytosol as drawn in the picture, but what happens to it?

  • @justinli3830
    @justinli3830 4 роки тому

    And on the 8th day, god created Sal Khan.

  • @AlexandroGiovanni
    @AlexandroGiovanni 3 роки тому

    Understood everything

  • @AvoirJoseph
    @AvoirJoseph 3 роки тому

    so... did you make a band named Endoplasmic Reticulum?

  • @m7warelcon622
    @m7warelcon622 Рік тому

    Can i study from this to the emsat exam?

  • @dlldll7482
    @dlldll7482 7 років тому +6

    I feel like in the entire video, all I got is "let me just draw....."

  • @hiitssofie
    @hiitssofie 4 роки тому +1

    ok watching this in 2019 and I have a question-- so how is the protein processed and "matured" when mRNA attaches itself to a free-floating ribosome instead of one that's attached to an E.R.?

    • @ROMAGNUM45
      @ROMAGNUM45 4 роки тому

      That's because of the mRNA. mRNA destined for the ER begins with what's called a signal peptide. As soon as that's translated a protein called SRP binds to it and then binds to the ER. The signal peptide is later cut off from the peptide string.
      A bit late but that is the gist of it.

  • @awesomenathan100
    @awesomenathan100 8 років тому

    Thank you so much this helped so much

  • @tariqkhanPathanKabuliwala
    @tariqkhanPathanKabuliwala 8 років тому

    Thank You

  • @surabhikanade3693
    @surabhikanade3693 8 років тому

    Thanks a ton

  • @that_one_girl_8064
    @that_one_girl_8064 5 років тому

    so is the cytosol the same as the cytoplasm, its just cytosol is more specific meaning out the substance between the organelles, or do you know have to know them both? and would you be penalised if you didnt?

    • @josephdahdouh2725
      @josephdahdouh2725 5 років тому +1

      Lol cytosol is everything that surrounds the organelles of the cell meaning without the Endoplasmic reticulum, nucleus... While cytoplasm is everything in the cell as a whole

  • @taamardhwaj
    @taamardhwaj 4 роки тому

    Why cell synthesise protein when we can have it by food?