This is why i love biology. So much is happening inside our body and we don't even realise it. I read these process multiple times in my book and then watched the animation. It really helped me thank you!
some of the first viewers are probably settled doctors by now. Same video that helped them continues to help us pre meds 16years later. What a legacy. What great content.
clearly explained, but with a few missing points, so it definitely helps a lot in my revision. 1. eukaryotic initiation factors first need to bind to the small ribosomal subunit to position the initiator tRNA properly at the P site. the later dissociate to allow binding of the large ribosomal subunit 2. the release factor adds a water molecule to the polypeptide to terminate translation and release the polypeptide chain 3. the amino acid is bound to the tRNA via an ester bond 4. peptide bonds are formed between the amino acids in the growing polypeptide chain 5. the entire process requires the hydrolysis of ATP
ATP Hydrolysis is necessary, but prior to the steps they are showing. The energy used from the hydrolysis of ATP is captured within the ester bond of tRNA to the amino acid.
This video is only 3 minutes long but it does such a better job than pages worth of textbook or 15 minute long videos. Thank you so much for making this, translation makes so much more sense now and it's actually way less complicated than it's made out to be in class.
Hi armies 😭😭 my mind is not in control, my exams are here and it's an imp toppic and I was only focusing on pictures😭... I think I will be broke throughout my life because I cannt focus and surely my marks will be low and hence broke for a life and will never be able to buy bts concert tickets👁👄👁 !!!! But I will try to focus 💜and that's only an option left eghh 😵
@@fine1876 Hi :) don't worry too much about it, yeah? Just try your best. Find a study method that suits you. Figure out when you need to start studying to cover all topics. In the last minute, I usually just scan through the notes and then locate the keyword. In the end, if you fail this one exam, don't beat yourself up too much. There are many things you can explore and learn so this failure should not define you.
This plus the transcription video have helped so much. I’m a visual learner so seeing this in an animation actually made me learn the material. My prof is the most monotone person Ive ever heard, and basically just tried to explain it all in words.
i was crying because the translation process was very difficult in the textbook , i was feeling like i will can't understand anything whatever i tried , i really feel happy because I found your talented channel you are helpful ❤️
I do a level biology and none of this was explained at all, not even in textbooks so I was very confused as to why the tRNA was even needed. I was also never told that the mRNA is between the sub units, this makes it so much more clearer, thank you!!
I am from India and targeting the neet exam which is basically a medical exam.......this video helps me more to understand the concept very clearly and sharply in a very Conqueised manner......So, lot's of love from india to this channel and i hope you will gain more and more subscriber and basically the translation is one of the most difficult topic as far as i know and many indian Neet aspirant r facing to understand this topic so your teaching method with 3d animation is just amazing😍👍🤩😍.......hope everyone will understand.....
This is the best video on translation ever! Maybe for more advanced students talk about how the bond between the amino acids is a Carbon-Nitrogen covalent bond. Also, something to add is that when translocation happens which is when the Ribosome moves down the mRNA it uses GTP as energy. When the first tRNA binds to the initiation codon it also uses GTP. When the amino acids are bound together it uses Peptidyl Transferase. A polysome is a single mRNA strand with all of the multiple ribosomes translating it at the same time. The signal on the end of the new polypeptide tells the ribosome to deliver it to the ER which is then post-translationally modified and edited.
Trust me better late than never! I love watching these videos and paraphrasing the contents to suit my exam questions :) Images in lecture notes help but seeing them actually MOVE is so much better! :D
THANK YOU! After hours of Kaplan Biochem, Doctors in Training, and essentially every other resource one can use for the USMLE Step 1, this topic still gave me fits. Your video changed that. God bless.
When studying from textbook... I found this so difficult and uninteresting... after struggling for a few days... Idk from nowhere it came to mind to look for a animation video for this process...and trust meh this one is the best... it's really helpful.. thanks again ❤
I couldnt visualize a thing. This video helped me so much. Lots of love from India. LOL it was made when i was 3 yo. Seen it 16 years later in college.
Clear and simple, and thanks for explaining the 5' 3' directionality! No mention of the proteins involved (such as peptidyl transferase which is what merges the amino acid of the A-site to the polypeptide of P-site), but a very nice guide to the overall process!
I have to say, I watched this video a year and a half ago for my first college Bio class and loved it. I am taking a similar class now and when we discussed it in class I was hoping I would find it again- and I did!
Really it's a awesome vdo..... Literally I just struggled with this topic.... But you make this crystal clear in just a minute.... Thankyou sooooo much
learned translation from this video in 10th grade and it's even a great refresher in college level bio! Will always visualize translation this way thanks to this perfect video!
The whole animation of this video is just so satisfying to watch plus the concept is explained so beautifully.. never understood this in class and now my mind is blown lol
Overall a nicely made video. Chemically, the transfer mechanism as cartoonized here, doesn't make sense, though: the peptide chain does not dissociate from the tRNA in the P-site and then attaches to the tRNA in the A-site. It's the amino group of the amino acid in the A-site that first attacks the carbonyl group of the amino acid in the P-site, forming a covalent bond in a tetrahedral intermediate, then forming the peptide bond and simultaneous breaking of the bond to the tRNA in the P-site.
I tried to read this in my textbook and had no idea what the HELL it was saying, you helped me get it in 3 and a half minutes. Thank you!
hahahaha same here
still hasnt watched the video yet. my hopes r high now
i think the problem with textbook explanations is, that it is quite abstract to be described with words. So the animation is very helpful
yeah. excellent explanation.👌👌
Hahaha. Yes same here kind-off 😂
I wasn't even born when this video was created, now after 16 years i'm watching this..... This video helped me a lot
This is why i love biology. So much is happening inside our body and we don't even realise it. I read these process multiple times in my book and then watched the animation. It really helped me thank you!
some of the first viewers are probably settled doctors by now. Same video that helped them continues to help us pre meds 16years later. What a legacy. What great content.
I WANT TO KISS THE PERSON WHO INVENTED THIS CHANNEL!
haha me too this channel is amazing...im in love
Batool Ali
U guys are gay
@@HASSAN-ey2qf how come u gotta know the person who opened this channel is a guy or an gal ?
Arpita Sahani maybe he’s bi nd doesn’t care shit of whome he’s kissin
Who's watching it in 2024?
Edited : wow now it's 2025 😀
me!
Me also
Meee😂
Mee to bro 🎉
And realizing it’s lgbtq
I found out about this video while in college. Helped me pass bio2, and now using it for biochem. Thanks, very helpful
+Julien Prégent im watching this video and im in 10th grade honors bio and we are doing this but yes super helpful! XD
+Koda Beck how are you in 10 grade and in honors bio
Im like in the 8th grade and this is basic Bio for us
@@alyannanedlei2 well congralations you learned a university level subject already
clearly explained, but with a few missing points, so it definitely helps a lot in my revision.
1. eukaryotic initiation factors first need to bind to the small ribosomal subunit to position the initiator tRNA properly at the P site. the later dissociate to allow binding of the large ribosomal subunit
2. the release factor adds a water molecule to the polypeptide to terminate translation and release the polypeptide chain
3. the amino acid is bound to the tRNA via an ester bond
4. peptide bonds are formed between the amino acids in the growing polypeptide chain
5. the entire process requires the hydrolysis of ATP
ATP Hydrolysis is necessary, but prior to the steps they are showing. The energy used from the hydrolysis of ATP is captured within the ester bond of tRNA to the amino acid.
POPsongsADDICT that was the very first step called charging of tRNA but its not added in the video
Yes some enzymes along with GTP are not mentioned.
😌
Thank you
@@doreamonunofficial848 * ATP
This video is only 3 minutes long but it does such a better job than pages worth of textbook or 15 minute long videos. Thank you so much for making this, translation makes so much more sense now and it's actually way less complicated than it's made out to be in class.
how does my body know how to do this and my brain can’t 😭
NICE😂
That's the saddest part of life 😢
😀😀
😂😂
And the biggest flex is that our brain cells know how to do it but our brain can't get it...
awesome....
no stupid useless disturbing background music
great explanation.
And no annoying accent
@@izgit meaning...
@@rahmahdalhat8484 I think they were being racist
This video was the first of many I've seen that actually had a easy to understand depiction of the continuous process of making proteins. Wonderful.
11 years old video. I was 7 years old when they uploaded it. Now here i am watching it the night before my A Level biology exam :)
Wish me luck :)
😊
how are you now?
Probably the most accurate and easy to understand videos about biological procedures on UA-cam thank you!
Are u Alive
Why am I paying £9000 a year?
9250
$35,000 lol love america
1,86,000 rupees....lol ,hate india
5000 RMB
@@sameersachan8427Rs.6000/yr. Gov. college still can't able to get this from books.
The process seems so long when I read it in the textbooks. So, thanks for this video! Very helpful!
they did leave a decent amount out (GTP expecially) but its a great start!
Wanna add what they left out?
You would also be a lifesaver thenXD
Hey Army ...
Hi armies 😭😭 my mind is not in control, my exams are here and it's an imp toppic and I was only focusing on pictures😭... I think I will be broke throughout my life because I cannt focus and surely my marks will be low and hence broke for a life and will never be able to buy bts concert tickets👁👄👁
!!!!
But I will try to focus 💜and that's only an option left eghh 😵
@@fine1876 Hi :) don't worry too much about it, yeah? Just try your best. Find a study method that suits you. Figure out when you need to start studying to cover all topics. In the last minute, I usually just scan through the notes and then locate the keyword. In the end, if you fail this one exam, don't beat yourself up too much. There are many things you can explore and learn so this failure should not define you.
This plus the transcription video have helped so much. I’m a visual learner so seeing this in an animation actually made me learn the material. My prof is the most monotone person Ive ever heard, and basically just tried to explain it all in words.
All joking aside this was a beautiful video 10/10 would watch again
AllTimeSnowman I CANNOT HELP IT I AM WATCHING AGAIN
AllTimeSnowman GOD HELP ME IT IS TOO BEAUTIFUL
Existential Sloth you must be done with school by now huh
@@ExistentialSlothWriting same i cant stop watching it
@@terigonUSAS12 I watched this like 10 times, a true masterpiece.
i was crying because the translation process was very difficult in the textbook , i was feeling like i will can't understand anything whatever i tried , i really feel happy because I found your talented channel you are helpful ❤️
@asimnissar no it's not 💀💔
This animation movie saved me from failing ~✨
@asimnissar i thought so too 😂
3h de travail incompréhensibles résumées en 3 minutes... merci !
Est-ce que je peux aller aux toilletes
Wait this was published 15 years ago??
This is so helpful thank uuuuu
Thank you so much! I’ve been staring at countless paragraphs and diagrams and not understanding translation, and this video helped a lot!
Man this video is fucking majestic and glorious as fuck. 10/10 would bang.
youre god damn fucking right this video is fucking gorgeous, i'd fuck it with a 10/10 fuckin A rating
@thepainkiller4939
best simplified, informative, soothing, well explained animation video i have ever seen. it was produced in 2008!
this is fucking beautiful... fucking amazing
Absolutely fucking gorgeous. Simply fucking spectacular.....
Truly fucking astounding.. fucking marvelous
I mean fuck me, this is good fucking shit.
you guys are so fucking right, I can't fucking even, I just fucking can't
Fuck me. Fuck the books, I fuck with that youtube fucking shit. It's fucking beneficial to my brain. Fuck.
Omg i have tears of joy, ncert is driving me nuts 😢 thank u so muchhhh
Studying for my test right now and this helped a lot! Thanks! :)
atb
This was very amazing, thank you so much! 16 years later and still helping students around the globe
waaay better than my lecturers at medical school!
Look at the mind blowing graphics. Hats off
This just saved my life. Thank you so much!!!!
After searching all other complex videos on UA-cam, I finally found this heavenly awesome video and got what I needed ......thanks...
I spent an hour studying this from my book but couldn't imagine well. But damn this video explained in to me within 4mins.
Wow, very nice. I understood the process in a simple and uncomplicated way. Following you from Iraq 🌼
AWESOME video. Thank you so much! This was so well explained - our professor should just use this video instead of showing us lecture slides.
Wait, aren't you that guy who made a liquid cooling PC guide? World is so small
i was crying with grief after reading the textbook and now I'm crying from happiness
This is one of greatest video i've seen in my whole life.
I share this video with all of my intro bio students and it is truly a God-send, as is this entire channel.
When I graduate, I'll ask for your hand in marriage.
Cool bruh💜
We will defined attend the wedding
Waoo😂😍😍
Woah 😀
Are you a graduate now?
I do a level biology and none of this was explained at all, not even in textbooks so I was very confused as to why the tRNA was even needed. I was also never told that the mRNA is between the sub units, this makes it so much more clearer, thank you!!
I am from India and targeting the neet exam which is basically a medical exam.......this video helps me more to understand the concept very clearly and sharply in a very Conqueised manner......So, lot's of love from india to this channel and i hope you will gain more and more subscriber and basically the translation is one of the most difficult topic as far as i know and many indian Neet aspirant r facing to understand this topic so your teaching method with 3d animation is just amazing😍👍🤩😍.......hope everyone will understand.....
Same
i
Such a great video - simple and explained everything clearly and concisely; what very student wants.
Keep making these :)
This is the best video on translation ever! Maybe for more advanced students talk about how the bond between the amino acids is a Carbon-Nitrogen covalent bond. Also, something to add is that when translocation happens which is when the Ribosome moves down the mRNA it uses GTP as energy. When the first tRNA binds to the initiation codon it also uses GTP. When the amino acids are bound together it uses Peptidyl Transferase. A polysome is a single mRNA strand with all of the multiple ribosomes translating it at the same time. The signal on the end of the new polypeptide tells the ribosome to deliver it to the ER which is then post-translationally modified and edited.
grear work.. our teacher should try this in the class!!
this is the best video about translation on youtube this was so well explained OMG
Trust me better late than never! I love watching these videos and paraphrasing the contents to suit my exam questions :)
Images in lecture notes help but seeing them actually MOVE is so much better! :D
Brilliant , precise and comprehensible explanation. Well done.
Amazing !!!
Love it so much..
thank you for beautiful animation
THANK YOU! After hours of Kaplan Biochem, Doctors in Training, and essentially every other resource one can use for the USMLE Step 1, this topic still gave me fits. Your video changed that. God bless.
Who is watching today>>>>>
Thank you so much, this has been so helpful. Please never take it down!
Excellent for biology students!!
13 years ago
Im still watching it and its still helping 😭😭😭😭
What
wow thanks to this video, I will pass my test!!!
I found this video to be really very helpful.The brief and animated description made translation topic extremely easy.
BLESS YOUR SOUL.
When studying from textbook... I found this so difficult and uninteresting... after struggling for a few days... Idk from nowhere it came to mind to look for a animation video for this process...and trust meh this one is the best... it's really helpful.. thanks again ❤
Neet walo hands up
Thank you. Easier to understand than just reading my textbook
thank you so much this was very helpful
I couldnt visualize a thing. This video helped me so much. Lots of love from India. LOL it was made when i was 3 yo. Seen it 16 years later in college.
I GET IT NOW
Clear and simple, and thanks for explaining the 5' 3' directionality! No mention of the proteins involved (such as peptidyl transferase which is what merges the amino acid of the A-site to the polypeptide of P-site), but a very nice guide to the overall process!
The most complicating part in all molucular biology 😭😭😭😭
finally i found such a fantastic animation video about the topic after searching an hour . really admirable sir keep it up.
Is this the protein produced by the hypothetical "gay gene"?
Thought so too!!! Hahaha
16 years later....and the legacy continues
I thought that i am the one who watches this video after 16 yearssss!!!! 😢😢😢
Btw I was just 3 years old,, when it was uploaded.. 🤧
THANK YOU U JUST SAVED MY BUTT FOR MY BIO TEST TODAY. I DIDNT GET ANYTHING AT ALL.
How are you in college and still play Minecraft
Giving you 10 out of 10 seriously so much helping video.... So beautifully depiction and easy style of speaking.... So helpful 🙏🙏
Help me I didn't get it
Who’s here from Ritu ma’am’s class (Vedantu)
Me but who are you?
After 15 year I'm hear for watching the video..! And thx for helping us📚🔬👏🏻
why is the protein gay?
.LOL😂😂😂
Theory wise ....it was cleared to me but...this video gave me a high quality imagination..🔥🔥
Praise to Jesus Christ!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Even this video is not detailed, it helped me to understand the basis of translation. Thank you❤
Thanks to this video, I've got a good score on biology exam. Thank you very much!
Since I'm a spatial learner...i found this video very useful and understood the concept very well...thanks
Thank you, beautiful human being who made this video, thank you.
I have to say, I watched this video a year and a half ago for my first college Bio class and loved it. I am taking a similar class now and when we discussed it in class I was hoping I would find it again- and I did!
Good!
It didn't take much of our time.
Was able to grasp the concept within a short span of time 🤩
thanku "christiana johnson" for making a amzing animation....u cleared my doubts...god bless u
Today is my biology board exam this helped me so much thankyou❤❤❤❤
such an amazing video please never delete❤🎉
This deserves more views ....
Really good video and simple explanation
Really it's a awesome vdo..... Literally I just struggled with this topic.... But you make this crystal clear in just a minute.... Thankyou sooooo much
After the 5 years of study now I get it in 3 mins. thank u..
THANK YOU!!! This made so much sense and the visuals really helped
learned translation from this video in 10th grade and it's even a great refresher in college level bio! Will always visualize translation this way thanks to this perfect video!
Thank you so much 🥰 I understood this concept so easily 🤗😄 Millions blessings to you 💞💞💫💫🧿🧿
They write it so complicated and hard to understand in books,and look how actually simple it looks on this animation
I find this video when I got totally confused about the translation proces but this animation make this really easy to understand.
IT EXPLAINS THE PROCESS SO CLEARLY! HELPS A LOT!!!!!!!!
Really good presentation. Finally, I understood the translation process. Thanks guys!
Why your voice is so awesome.
Jokes apart!
Thank you.. You made everything so simple
The whole animation of this video is just so satisfying to watch plus the concept is explained so beautifully.. never understood this in class and now my mind is blown lol
This video made my concept crystal clear 😌.....tqsm 🤗
Overall a nicely made video. Chemically, the transfer mechanism as cartoonized here, doesn't make sense, though: the peptide chain does not dissociate from the tRNA in the P-site and then attaches to the tRNA in the A-site. It's the amino group of the amino acid in the A-site that first attacks the carbonyl group of the amino acid in the P-site, forming a covalent bond in a tetrahedral intermediate, then forming the peptide bond and simultaneous breaking of the bond to the tRNA in the P-site.
absolutely helpful! I have a test tomorrow and I couldn't understand this! thank you so much!
U r amazing i love you 💕💕💕💕 thankyou for making this i just needed this right now