New Long Covid Breakthrough! First step towards a treatment?? Dr Gill

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  • Опубліковано 17 чер 2024
  • New Long Covid Breakthrough! Inflammatory Markers Identified? Dr Gill
    One of the major problems with long Covid, as we don't really know what is that is the underlying mechanisms behind the symptoms we're dealing with.
    But a new paper for Dr Liew et al may have shed some light on this and allowed the identification of five different phenotypes of Long COvid
    Here is the paper in question
    www.nature.com/articles/s4159...
    #DRGill #Longcovid #Covid
    00:00 - Introduction
    00:19 - Overview of the Study
    01:05 - Importance of the Study and Its Future Impact
    01:34 - Details of the Patient Group Studied
    02:40 - Study Methodology
    03:27 - Key Findings of the Study
    04:05 - Why is Long COVID So Tough to Crack?
    05:24 - Complement System Activation and Processes
    09:07 - Complement System and Long COVID
    10:04 - Future Treatment Directions
    11:50 - Final Thoughts
    13:31 - Closing Remarks

КОМЕНТАРІ • 107

  • @AM_o2000
    @AM_o2000 Місяць тому +11

    As someone who has been disabled by ME/CFS for more than a decade, this video just gave me a glimmer of hope that the condition might be understood and possibly even treatable in my lifetime.

  • @slickrat
    @slickrat Місяць тому +41

    I think I speak for many that we still feel so bad for Diana "The Physics Girl" here on UA-cam, for her Long-Covid simptoms (being bed-bound for years).
    My heart goes to all people in a similar situation...
    (may studies like this one bring some hope)

    • @ronbunn1349
      @ronbunn1349 Місяць тому

      @@neox6439usually people who study physics are not scientifically illiterate anti-vax types

  • @aarongomes314
    @aarongomes314 27 днів тому +5

    As a long covid sufferer I appreciate you providing us with some positive news - sounds like we are one step closer to a potential treatment. Please keep us informed of any further advancements. Cheers.

  • @shelley7209
    @shelley7209 Місяць тому +41

    I want a CURE not a test

    • @MyFriendPeter
      @MyFriendPeter Місяць тому +3

      Post viral illness has been known about for decades to centuries.
      Unfortunately we are so far behind research and treatment that we are starting at the beginning of diagnosis.
      You can blame Drs for not treating the illness seriously or believing it.
      Government for misspending taxes on rubbish for people who don't deserve help.
      The pharmaceutical industry for not caring
      And the rest of the population shouting louder at their supposed problems for help.
      Berlin Cures seem to be the hope to look out for on their work of autoimmunity

  • @borge2014
    @borge2014 Місяць тому +7

    A serious subject made easy to digest and visualize. Thank you! I can listen to Dr. Gill for hours.

  • @cuteface88
    @cuteface88 Місяць тому +7

    Such a travesty what the professionals have done to us all. A real crime against humanity.

  • @cocolamonte2458
    @cocolamonte2458 Місяць тому +7

    Amazing break down of the study, thank you so much. Excellent that you mentioned ME too as 80% of ME patients became ill after a virus or infection. I’ve thought for a long time it’s an autoimmune condition so I await more studies like this into LC with optimism

  • @georgewalford7027
    @georgewalford7027 Місяць тому +11

    This was great, would love to see more like this.

  • @dbulat
    @dbulat Місяць тому +7

    Nearly 2 years of suffer. F This disease. Please, find a cure for that mess.

  • @Noellius2
    @Noellius2 Місяць тому +5

    Unfortunately, insurance companies in the USA are starting to deny coverage of biologics for those of us who are symptomatic but without diagnostic tools to specify the mechanism that's going wrong.

  • @keittomaster
    @keittomaster Місяць тому +3

    Yes, real scientific and academic analysis on youtube! What a breath of fresh air!

  • @jamesbuerger9361
    @jamesbuerger9361 Місяць тому +2

    My life will peak if I learn the cure for long covid via ASMR
    Seriously, as a person on medical leave from long covid, please do more of these!

  • @VampyressVA
    @VampyressVA 10 днів тому

    Thank you for the amazing content. You are so witty and soft spoken, I could listen to you forever!

  • @Iwoodlikethat
    @Iwoodlikethat Місяць тому +9

    I liked this format and would appreciate more please

  • @EdBrewster
    @EdBrewster Місяць тому +1

    Wow, thank you SO SO much for this, you explained it really well, and as a Long Covid sufferer myself, gave me a tiny bit of hope. You’re a legend, Dr Gill.
    Please explain more papers!

  • @gwilkins4617
    @gwilkins4617 Місяць тому +4

    Keep the long COVID/ CFS vids coming!

  • @stoneblue294
    @stoneblue294 Місяць тому

    Thank you for putting together this video.

  • @jamiew.2718
    @jamiew.2718 Місяць тому +16

    ++ for more paper discussions!

  • @Nucl34r_W1nt3r
    @Nucl34r_W1nt3r Місяць тому +1

    Very informative doc. Would love to see more like this !

  • @Jay-bv4yy
    @Jay-bv4yy 3 дні тому

    Great video!!! Thank you 🙏

  • @msaditu
    @msaditu Місяць тому

    Excellent video! Very good information.

  • @saffire301
    @saffire301 Місяць тому

    Great job

  • @helenhucker346
    @helenhucker346 Місяць тому +3

    Thank you very much Dr Gill and I would certainly appreciate more such videos.
    Does this latest research suggest that Long COVID has now become another autoimmune disease?

  • @garnerblair5179
    @garnerblair5179 10 днів тому

    With homocysteine being a marker for so many disease processes, i propose that MTHFR polymorphisms will make up the bulk of long-covid/vax sufferers. Also notable that even if you dont have a MTHFR polymorphism, you can mimick it with the modern/western diet .

  • @rosschambers1987
    @rosschambers1987 Місяць тому +1

    Thanks for the interesting video. Does the same apply for those suffering with long term systemic illness similar to long covid but instead related to the medical intervention we all took? I am struggling with palpitations, exercise induced fatigue, brain fog/unpleasant sensations in my head, insomnia. I get a few good days but then get slammed back down. Trying HBOT at the moment and have previously tried so many other different things with no joy.

  • @TenkoBerry
    @TenkoBerry Місяць тому +1

    This is Pretty Good Information 👌

  • @black.pinktrading5705
    @black.pinktrading5705 Місяць тому +1

    This was so interesting, the explanations made so much sense even to someone who has zero medical knowledge ahah 😂 I would love too more videos like this in the future 😌😌😌

  • @hannafloyd
    @hannafloyd Місяць тому +1

    First thing I thought of was hope for Physics Girl ❤

  • @rainerwein8604
    @rainerwein8604 Місяць тому

    interesting it took the researchers such a long time to identify the blood as a related problem, though the acquired antiphospholipidsyndrome due to PostVac and PostCovid has been known since quite some years by now....

  • @user-fo5ic3nz6j
    @user-fo5ic3nz6j Місяць тому

    I now have been diagnosed with COPD and Asuma

  • @PurposefulPorpoise
    @PurposefulPorpoise Місяць тому

    Remnant Viral Reservoir. Thats my bet. Treatment will have to be similar to Hep C. Heat Therapy or some miraculous new anti-viral.

  • @Gina-dn6xm
    @Gina-dn6xm Місяць тому +3

    I had a research doctor in which I took a special blood test . I tested positive for high inflammation markers. The protocol included an AIDS drug and a steroid. The trouble here in the US , doctors can lose their licenses for prescribing off label drugs. After asking 5 doctors, I just gave up.
    The AIDS medication is an immune modulator. By the way, I'm mostly bed bound and home bound by extreme fatigue.

    • @lowandslow3939
      @lowandslow3939 29 днів тому

      Was that Dr. Bruce Patterson and his team? I had tons of bloodwork done by his lab and also took HIV drugs off label. The numbers in my bloodwork improved but my symptoms continued until I got Covid for the second time. I’ll do one or two half days of work and then have to sleep for several days, all damn day and night. So sick and tired of being sick and tired.

    • @Gina-dn6xm
      @Gina-dn6xm 29 днів тому

      @lowandslow3939 Yes, that is the doctor I was referring to. I'm sorry the treatment didn't work for you. I have heard that it works for some people but not all. I know what it is like to try to chase a cure, and nothing is working. I hope someday research can find medications that can help us all. But to be honest, I'm not holding my breath on that one. I've been sick too long, like you.

    • @lowandslow3939
      @lowandslow3939 28 днів тому +1

      @@Gina-dn6xm Thanks for the response. I also believe his protocol helps many, but not all. I’ve pretty much accepted that this is my life for the foreseeable future. It sucks and it’s better than being dead, but not by much.

    • @Gina-dn6xm
      @Gina-dn6xm 28 днів тому

      @lowandslow3939 I totally agree. I think I will be dead before they find medication that either cures us or keeps us in remission. The cruel thing about this disease is you don't die and you don't get better; you are a living, breathing, mostly bedbound person . The days turn into months, the months to years, and nothing changes.

    • @lowandslow3939
      @lowandslow3939 27 днів тому +1

      @@Gina-dn6xm Another horrible aspect is that family members don’t understand and constantly tell me what they think, or heard will cure it. I’ve tried everything you can think of. I’m writing most of them off, almost wishing that just one of them would get it too, and validate my claims. My own mother tells me that if I don’t follow her directives, then I just don’t want to get better. She has no medical education but watches podcasts. Thanks mom but Ivermectin won’t cure it.

  • @ground752
    @ground752 5 днів тому

    I do wish a fix was possible

  • @traianliviudanciu8665
    @traianliviudanciu8665 29 днів тому

    May be trigger is some IgM cryoglobuline ?

  • @lessons9745
    @lessons9745 7 днів тому

    I got post infectious illness after I got a bacterial hospital acquired superbug infection in 2016 ..I have pots and who knows what else . have you heard of Berlin cures ?

  • @lowandslow3939
    @lowandslow3939 29 днів тому +1

    I was a patient of Dr. Bruce Patterson and did a ton of bloodwork, consultations and meds, including off label HIV meds. My bloodwork numbers improved but my symptoms hit a plateau. After my second case of Covid, they worsened considerably. Are you familiar with his work? We knew more than a year ago that I have severe inflammation but not how to rein it in. I’m bed bound about 3-4 days per week. So tired of this.

    • @MichaelMerritt
      @MichaelMerritt 27 днів тому +1

      I’ve done the same with his protocol. My LC is strongly mast cell with some heart rate issues and mild dysautonomia. I’ve had some recent luck managing symptoms with ivermectin (blocks prostaglandins and reduces inflammation) and mast cell stabilizers like oral sodium cromolyn. Everyone is different but that has been helping me a lot.

    • @MichaelMerritt
      @MichaelMerritt 27 днів тому

      I’m still waiting to figure out how to rid of viral persistence if that’s the root of all this mess. Miraviroc wasn’t it for me.

  •  Місяць тому +1

    I have had Long-Covid for over 4 years now, Dr Gill. The symptoms seem to be very much consistent with symptoms of Mast Cell Activation Syndrome, which is often hard to detect, diagnose and treat as well. Could there be a link between Long-Covid and MCAS in your view?

    • @MichaelMerritt
      @MichaelMerritt 27 днів тому +1

      I’ve had a lot of luck managing symptoms with oral sodium cromolyn (liquid 100mg bottle; start slow) and ivermectin 15mg every 3 days. Took me from bed ridden to functioning and occasionally able to workout. I’ve had LC for 4 years now. Not a cure but as close as I’ve gotten. Ivermectin helps reduce some of the cytokines and blocking prostaglandins which triggers mast cells. Helped a lot with brain fog. I hope you get well.

    • @Ytdeletesallmycomments
      @Ytdeletesallmycomments 25 днів тому

      Yes!
      Change your dieet.
      Fast
      Than omad
      Low histamine food
      No sugar and processed food
      Tulsi
      Quercetine
      Vit c d zink
      B
      Woodworm
      Charcoal
      Milk thistle
      Kurkuma
      After two days you will feel it.
      Go outside or sit on a bad day in the sun.
      Keep moving.
      Smile.
      Eat bad
      Crash
      Start over
      ...

    • @MJR1117
      @MJR1117 21 день тому +1

      Long covid isn't just one condition. It can be 2 or more. MCAS is one of the most common

  • @Fliptheflipflop
    @Fliptheflipflop 29 днів тому +1

    I've been hearing a lot about how it could be viral persistence, this would imply it's not an autoimmune problem right?

    • @DrJamesGill
      @DrJamesGill  29 днів тому +1

      I think there are several processes. Clotting issue, autoimmune responses, histamine reaction, gut dysbiosis and viral persistence / reactivation
      The question is which are symptoms and which are causative

    • @Fliptheflipflop
      @Fliptheflipflop 29 днів тому

      @@DrJamesGill thanks for the reply doc

  • @user-fo5ic3nz6j
    @user-fo5ic3nz6j Місяць тому

    I coded twice in the hospital fighting for my life in ICU, life support, trak,intabated, total kidney failure and dyalises. Now my kidneys are working at 40%. I have had 2 ANA blood test done my number is 42. I hurt, I had dropped feet and feet stopped working and my left arm and left side of my face and had swallow issues while in the hospital, I can move my left arm and I am finally walking, but have limitations in my feet and legs, my hands and fingers are still problematic

    • @jamesneilsongrahamloveinth1301
      @jamesneilsongrahamloveinth1301 10 годин тому

      Could it be related to the medical intervention which was supposed to stop Covid (but didn't) . . .

  • @user-fo5ic3nz6j
    @user-fo5ic3nz6j Місяць тому

    I have lost of pain,I'm tired all the time, I am now medically disabled

  • @user-fo5ic3nz6j
    @user-fo5ic3nz6j Місяць тому

    Is there any chance of getting treatment or a way to help with my pain. I have anxiety and stress and depression. Have lots of painful inflammatory issues.

    • @Ytdeletesallmycomments
      @Ytdeletesallmycomments 25 днів тому

      Change your dieet.
      Fast
      Than omad
      Low histamine food
      No sugar and processed food
      Tulsi
      Quercetine
      Vit c d zink
      B
      Woodworm
      Charcoal
      Milk thistle
      Kurkuma
      After two days you will feel it.
      Go outside or sit on a bad day in the sun.
      Keep moving.
      Smile.
      Eat bad
      Crash
      Start over
      ...

  • @samir5118
    @samir5118 Місяць тому

    Hey doctor. When we eat meat, the stomach digests the meat. But why, when we are hungry, does the stomach not digest itself when it is made of meat?

  • @wzupppp
    @wzupppp 29 днів тому

    Is autoimmunity caused by wrong signals from the brain?

  • @user-fo5ic3nz6j
    @user-fo5ic3nz6j Місяць тому

    I had Covid19 July of 2020 and came home January 2021

  • @traianliviudanciu8665
    @traianliviudanciu8665 29 днів тому

    High SARS COV2 replication will, theoretically,induce more inflammatory reaction.
    Did we know at what tissue temperature did SARS COV2 better replicate ?
    Why ?
    Because in 2020 at TWiV 659 at min29 virologist Christian Drosten suggest that SARS COV2 better replicate at low tissue temperature (35 -34C)

  • @wolfblood178
    @wolfblood178 Місяць тому

    ive had covid 3 times, i might now have it a 4th...

  • @user-tn8fd4xo8t
    @user-tn8fd4xo8t Місяць тому +5

    Two years long....so tired of this....

    • @DrJamesGill
      @DrJamesGill  Місяць тому +1

      Oh dear. I’m sorry you’ve had it that long. I do honestly believe we’ll get better treatments. We’re trying to use as much information as possible for our patients

    • @ArtTaggerr-223
      @ArtTaggerr-223 Місяць тому

      @@DrJamesGillI believe the key to understanding this illness is to compare those vaccinated to non-vaccinated, and the degree-symptoms of Covid long. Surely AI can help! The challenge is to get both sample groups to admit to ANY health changes.

    • @buppiano
      @buppiano Місяць тому +1

      Four years with diagnosed Long Covid, POTS, MCAS, Not vaxed. Could really use a cure so I can have a life.

    • @Ytdeletesallmycomments
      @Ytdeletesallmycomments 25 днів тому

      ​@@buppianoChange your dieet.
      Fast
      Than omad
      Low histamine food
      No sugar and processed food
      Tulsi
      Quercetine
      Vit c d zink
      B
      Woodworm
      Charcoal
      Milk thistle
      Kurkuma
      After two days you will feel it.
      Go outside or sit on a bad day in the sun.
      Keep moving.
      Smile.
      Eat bad
      Crash
      Start over
      ...

  • @sonrog8877
    @sonrog8877 9 днів тому

    The voice quality is so bad it’s painful to listen to. Any way to improve?

  • @user-fo5ic3nz6j
    @user-fo5ic3nz6j Місяць тому

    I have long Covid19

  • @danmarquez3971
    @danmarquez3971 Місяць тому +3

    I say that long COVID is the result of exposure to COVID or COVID vaccines during a condition that increases IL-4 and IL-10. Why? These increase IgG4. So an ongoing allergy increases IL-4. Hypoxia increases IL-10. So the cure may be a reduction of LI-4, IL-10, and IgG4.

    • @danmarquez3971
      @danmarquez3971 Місяць тому +1

      I also suspect that BanLec may fix IgG4 by making it trigger liver complement cascades.

  • @pauljarvis5384
    @pauljarvis5384 Місяць тому +39

    I have long baldness

    • @jamiew.2718
      @jamiew.2718 Місяць тому +2

      Have you tried keeps

    • @kathrynletchford5114
      @kathrynletchford5114 Місяць тому +1

      😂😂😂

    • @Bryce433
      @Bryce433 Місяць тому

      @@shelley7209 yes

    • @jamiew.2718
      @jamiew.2718 Місяць тому +2

      @@shelley7209 are you making fun of people with hair loss?

    • @shelley7209
      @shelley7209 Місяць тому

      @@jamiew.2718 I’m happy you came to a site where people have lost their health, homes and way of life over baldness! Thanks for coming

  • @grahamcracker7129
    @grahamcracker7129 Місяць тому

    All that just to say… no one still has a clue what’s going on.

  • @snorgonofborkkad
    @snorgonofborkkad Місяць тому +1

    What’s long covid?

    • @DrJamesGill
      @DrJamesGill  Місяць тому +1

      The definition is Covid symptoms remaining 12 weeks after initial infection, and here is the crucial bit, not explained by other pathology.
      In the long Covid clinic we spend a long time ruling out other things

    • @ArdGeal
      @ArdGeal 11 днів тому

      A vague set of symptoms attributable to people who enjoyed furlough so much they couldn't face going back to their shi**y jobs and wa*ker bosses.... be interested to see the stats for "long covid" vs jabbed and unjabbed status though....

  • @user-lf4zw4es7i
    @user-lf4zw4es7i 5 годин тому

    Long vaccine

  • @jamesneilsongrahamloveinth1301
    @jamesneilsongrahamloveinth1301 10 годин тому

    How much Long Covid is actually the side effects of the medical intervention which was mandated to so many . . . ?

  • @Mr.propre1
    @Mr.propre1 Місяць тому

    Peut-on dire que c'est de la faute des immigrés ? Je pose la question.

  • @matthewfurlani8647
    @matthewfurlani8647 Місяць тому +3

    strange, you don't have a "please contact the CDC for more information" placard on your video. very interesting 🤔

    • @DrJamesGill
      @DrJamesGill  Місяць тому +13

      I’m not American and this was a British study, I don’t have any connection to the Cdc

    • @charlietango936
      @charlietango936 Місяць тому

      ...🤨

    • @DrJamesGill
      @DrJamesGill  Місяць тому +3

      Ok my side it has a link to the NHS now. Perhaps just took time for the system to do it’s thing 😊