Medical School Pathology: Clinical Aspects of Neoplasia

How does cancer cause harm? This video for medical students focuses on the effects that a tumor has on the patient: local and hormonal effects, cachexia and paraneoplastic syndromes. Tumor grading and staging are also addressed. This material is based on Robbins & Kumar Basic Pathology, 11th edition.

[@PathologyCentral]

Have you ever wondered WHY & HOW cancer kills? WHY patients with advanced cancer become incredibly thin and weak? This video helps make the connection between the basic science (pathophysiology) and your future patients!

[@ahmedsiro1656]

Thank you so much for uploading these video's. Its really helpful to use as a supplemental notes for pathology

[@moshesadofsky9429]

I like this topic. Another way to distinguish Stage from Grade: Stage is only about anatomic location. You really don't need to examine the cells at all, just know where they are. Are they are only in their original location? Have they invaded locally? Have they spread to lymph nodes? More distant locations?
Grading is any description of the individual cells, and can include appearance, mutations, mitotic activity, proteins they make or secrete. Sequence information is usually part of Grading, although this can contribute to subtle aspects of staging. Immunochemistry too is a part of grading. Both are important for clinical decision making, and sequence information is increasingly important.

[@PathologyCentral]

A most excellent contribution, Dr. Sadofsky. Thank you!